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Coca Wine
Coca wine is an alcoholic beverage combining wine with cocaine. One popular brand was ''Vin Mariani'', developed in 1863 by French-Corsican chemist and entrepreneur Angelo Mariani. At the end of the 19th century, the fear of drug abuse made coca-based drinks less popular. This led to the prohibition of cocaine in the United States in 1914 via the Harrison Narcotics Tax Act, and the removal of cocaine from coca wine, though coca leaf remained. Coca wine itself became illegal in the United States when its other main drug, alcohol, was banned just a few years later with the Eighteenth Amendment in 1920. Peruvian Wine of Coca.png, Peruvian Wine of Coca Médaille Coca Mariani revers O.Roty.JPG, Coca Mariani medal by Louis-Oscar Roty Related beverages In Atlanta, John Pemberton, a pharmacist, developed a beverage based on Vin Mariani, called Pemberton's French Wine Coca. It proved popular among American consumers. In 1886, when Georgia introduced Prohibition, Pemberton had to repl ...
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Vin Mariani Publicite156
Vin or VIN may refer to: Arts, entertainment, and media * Vîn TV, a Kurdish language satellite television channel founded in 2007 * ''Vos Iz Neias?'', an American Jewish online news site * Coastal radio station VIN Geraldton (callsign), a station in the former Australian coastal radio service Fictional characters * Vin, a character in the video games ''Jak II'' and ''Jak 3'' * Vin, the primary character in the ''Mistborn'' series by Brandon Sanderson * Vin Gonzales, a Spider-Man/Marvel Comics supporting character * Vin Petrol, a character in the ''Corner Shop Show'' Places * Havryshivka Vinnytsia International Airport (IATA code), Vinnytsia, Ukraine * Vin, California, an unincorporated community in the US * Saint Vincent and the Grenadines (country code) Science and technology * Vehicle identification number, a 17-character unique identifying code for motor vehicles * Voltage input (''Vin''); for example in a voltage divider * Vulvar intraepithelial neoplasia, particular ch ...
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Atlanta
Atlanta ( ) is the capital and most populous city of the U.S. state of Georgia. It is the seat of Fulton County, the most populous county in Georgia, but its territory falls in both Fulton and DeKalb counties. With a population of 498,715 living within the city limits, it is the eighth most populous city in the Southeast and 38th most populous city in the United States according to the 2020 U.S. census. It is the core of the much larger Atlanta metropolitan area, which is home to more than 6.1 million people, making it the eighth-largest metropolitan area in the United States. Situated among the foothills of the Appalachian Mountains at an elevation of just over above sea level, it features unique topography that includes rolling hills, lush greenery, and the most dense urban tree coverage of any major city in the United States. Atlanta was originally founded as the terminus of a major state-sponsored railroad, but it soon became the convergence point among several rai ...
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Mixed Drinks
A mixed drink is a beverage in which two or more ingredients are mixed. Types * List of non-alcoholic mixed drinks -- A non-alcoholic mixed drink (also known as virgin cocktail, boneless cocktail, temperance drink, or mocktail) is a cocktail-style beverage made without alcoholic ingredients. * Soft drink Psychoactive * Coffee drinks: Iced coffee * List of chocolate drinks — chocolate contains a small amount of caffeine * Energy drink * Kava — not traditionally flavored, however, it is occasionally flavored like alcoholic drinks. * Teas Alcoholic A "spirit and mixer" is any combination of one alcoholic spirit with one non-alcoholic component, such as gin and tonic, whereas a cocktail generally comprises three or more liquid ingredients, at least one of which is alcoholic. * List of cocktails * List of beer cocktails * List of flaming beverages * List of national drinks * List of wine cocktails Supplies * List of glassware * List of common edible cocktail garnishes * List ...
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Cocaine
Cocaine (from , from , ultimately from Quechuan languages, Quechua: ''kúka'') is a central nervous system (CNS) stimulant mainly recreational drug use, used recreationally for its euphoria, euphoric effects. It is primarily obtained from the leaves of two Coca species native to South America, ''Erythroxylum coca'' and ''Erythroxylum novogranatense''. After extraction from coca leaves and further processing into cocaine hydrochloride (powdered cocaine), the drug is often Insufflation (medicine), snorted, applied topical administration, topically to the mouth, or dissolved and injection (medicine), injected into a vein. It can also then be turned into free base form (crack cocaine), in which it can be heated until sublimated and then the vapours can be smoking, inhaled. Cocaine stimulates the mesolimbic pathway, reward pathway in the brain. Mental effects may include an euphoria, intense feeling of happiness, sexual arousal, psychosis, loss of contact with reality, or psychomo ...
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Cardiotoxic
Cardiotoxicity is the occurrence of heart dysfunction as electric or muscle damage, resulting in heart toxicity. The heart becomes weaker and is not as efficient in pumping blood. Cardiotoxicity may be caused by chemotherapy (a usual example is the class of anthracyclines) treatment and/or radiotherapy; complications from anorexia nervosa; adverse effects of heavy metals intake; the long-term abuse of or ingestion at high doses of certain strong stimulants such as cocaine; or an incorrectly administered drug such as bupivacaine. One of the ways to detect cardiotoxicity at early stages when there is a subclinical dysfunction is by measuring changes in regional function of the heart using strains. See also * Cardiotoxin III * Batrachotoxin * Heart failure * Drug interaction Drug interactions occur when a drug's mechanism of action is disturbed by the concomitant administration of substances such as foods, beverages, or other drugs. The cause is often the inhibition of the speci ...
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Cocaethylene
Cocaethylene (ethylbenzoylecgonine) is the ethyl ester of benzoylecgonine. It is structurally similar to cocaine, which is the methyl ester of benzoylecgonine. Cocaethylene is formed by the liver when cocaine and ethanol coexist in the blood. In 1885, cocaethylene was first synthesized (according to edition 13 of the ''Merck Index''), and in 1979, cocaethylene's side effects were discovered. Metabolic production from cocaine Cocaethylene is the byproduct of concurrent consumption of alcohol and cocaine as metabolized by the liver. Normally, metabolism of cocaine produces two primarily biologically inactive metabolites—benzoylecgonine and ecgonine methyl ester. The hepatic enzyme carboxylesterase is an important part of cocaine's metabolism because it acts as a catalyst for the hydrolysis of cocaine in the liver, which produces these inactive metabolites. If ethanol is present during the metabolism of cocaine, a portion of the cocaine undergoes transesterification with ethanol, ...
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Coca-Cola
Coca-Cola, or Coke, is a carbonated soft drink manufactured by the Coca-Cola Company. Originally marketed as a temperance drink and intended as a patent medicine, it was invented in the late 19th century by John Stith Pemberton in Atlanta, Georgia. In 1888, Pemberton sold Coca-Cola's ownership rights to Asa Griggs Candler, a businessman, whose marketing tactics led Coca-Cola to its dominance of the global soft-drink market throughout the 20th and 21st century. The drink's name refers to two of its original ingredients: coca leaves and kola nuts (a source of caffeine). The current formula of Coca-Cola remains a closely guarded trade secret; however, a variety of reported recipes and experimental recreations have been published. The secrecy around the formula has been used by Coca-Cola in its marketing as only a handful of anonymous employees know the formula. The drink has inspired imitators and created a whole classification of soft drink: colas. The Coca-Cola Company p ...
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Syrup
In cooking, a syrup (less commonly sirup; from ar, شراب; , beverage, wine and la, sirupus) is a condiment that is a thick, viscous liquid consisting primarily of a solution of sugar in water, containing a large amount of dissolved sugars but showing little tendency to deposit crystals. Its consistency is similar to that of molasses. The viscosity arises from the multiple hydrogen bonds between the dissolved sugar, which has many hydroxyl (OH) groups. Culinary syrup There are a range of syrups used in food production, including: * Agave syrup, made from agave stem * Cane syrup, made from sugar canes * Chocolate syrup * Corn syrup * Glucose syrup * Golden syrup, a by-product of refining crystallized sugar * High fructose corn syrup, widely used in the US * Maple syrup Common syrups A variety of beverages call for sweetening to offset the tartness of some juices used in the drink recipes. Granulated sugar does not dissolve easily in cold drinks or ethyl alcohol. Since ...
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Prohibition In The United States
In the United States from 1920 to 1933, a Constitution of the United States, nationwide constitutional law prohibition, prohibited the production, importation, transportation, and sale of alcoholic beverages. The alcohol industry was curtailed by a succession of state legislatures, and finally ended nationwide under the Eighteenth Amendment to the United States Constitution, ratified on January 16, 1919. Prohibition ended with the ratification of the Twenty-first Amendment to the United States Constitution, Twenty-first Amendment, which repealed the Eighteenth Amendment on December 5, 1933. Led by Pietism, pietistic Protestantism in the United States, Protestants, prohibitionists first attempted to end the trade in alcoholic drinks during the 19th century. They aimed to heal what they saw as an ill society beset by alcohol-related problems such as alcoholism, Domestic violence, family violence, and Saloon bar, saloon-based political corruption. Many communities introduced al ...
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Pemberton's French Wine Coca
Pemberton's French Wine Coca was a coca wine created by the druggist John Pemberton, the inventor of Coca-Cola. It was an alcoholic beverage, mixed with coca, kola nut, and damiana. The original recipe contained the ingredient cocaethylene (cocaine mixed with alcohol), which was removed, just like the alcohol had before it, in 1899 because of a social stigma surrounding the rampant use of cocaine at the time. History French wine coca is a combination of cocaethylene (a unique drug made by mixing cocaine and alcohol) and French wine. In 1863, a Parisian chemist Angelo Mariani combined coca and wine and started selling it under the name " Vin Mariani". This became extremely popular. Jules Verne, Alexander Dumas, and Arthur Conan Doyle were among literary figures said to have used it, and the chief rabbi of France is quoted to have said, "Praise be to Mariani's wine!" Pope Leo XIII reportedly carried a flask of it regularly and gave Mariani a medal. Seeing this commercial su ...
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John Pemberton
John Stith Pemberton (July 8, 1831 – August 16, 1888) was an American pharmacist and Confederate States Army veteran who is best known as the inventor of Coca-Cola. In May 1886, he developed an early version of a beverage that would later become Coca-Cola, but sold his rights to the drink shortly before his death. He suffered from a sabre wound sustained in April 1865, during the Battle of Columbus. His efforts to control his chronic pain led to morphine addiction. He began to experiment with various painkillers and toxins. In the end, after development of an earlier beverage blending alcohol and cocaine, this led to the recipe that later was adapted to make Coca-Cola. Background Pemberton was born on July 8, 1831, in Knoxville, Georgia, and spent most of his childhood in Rome, Georgia. His parents were James C. Pemberton and Martha L. Gant. The Pembertons were of English lineage, the direct paternal ancestor Phineas Pemberton and his family from Lancashire, traveled aboard ...
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Louis-Oscar Roty
Louis-Oscar Roty usually known as Oscar Roty (11 June 1846 – 23 March 1911) was one of the most celebrated medallists of the Art Nouveau period. Biography Louis-Oscar Roty was born on 11 June 1846 in Paris. He first studied painting and sculpture, working under Lecoq de Boisbaudran, Augustin-Alexandre Dumont and Hubert Ponscarme, his mentor, was largely responsible for the renewal of medallic art at the end of the nineteenth century. In 1867 he had abandoned the medal rim in his design for his medal of Naudet, the background and graphics becoming part of the sculpture. Roty, along with Champlain, Alexandre Charpentier, and others, influenced by the Art Nouveau movement, advanced this resurgence of art in medal design. Roty, in particular, introduced the Renaissance form of the plaquette, which further emphasized the significance of the medal as a work of art. He designed hundreds of art medals celebrated for their graceful designs. Following some difficulties early in ...
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