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Vaccitech
Vaccitech plc is a biotechnology company developing vaccines and immunotherapies for infectious diseases and cancer, such as hepatitis B, HPV and prostate cancer. Technology The company's platform includes Chimpanzee Adenovirus Oxford ( ChAdOx) and Modified Vaccinia Ankara (MVA), two viral vectors which safely mimic viral infection in human cells and elicit antibody and T cell responses to pathogens and tumours. History The company was founded in 2016 as a University spin-off by Sarah Gilbert and Adrian V. S. Hill at The Jenner Institute, University of Oxford. Vaccitech has been financed and supported by M&G Catalyst, Google Ventures (GV), Fosun International, Tencent, Huawei, Sequoia Capital, GeneMatrix, Liontrust Asset Management, Korea Investment Partners and Oxford Sciences Innovation (OSI). In early 2020, Vaccitech and the University of Oxford co-invented a vaccine for COVID-19 using the ChAdOx platform. COVID-19 vaccine In July 2020, it was reported that people in ...
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Sarah Gilbert
Dame Sarah Catherine Gilbert (born April 1962) is an English vaccinologist who is a Professor of Vaccinology at the University of Oxford and co-founder of Vaccitech. She specialises in the development of vaccines against influenza and emerging viral pathogens. She led the development and testing of the universal flu vaccine, which underwent clinical trials in 2011. In January 2020, she read a report on ProMED-mail about four people in China suffering from a strange kind of pneumonia of unknown origin in Wuhan. Within two weeks, a vaccine had been designed at Oxford against the new pathogen, which later became known as COVID-19. On 30 December 2020, the Oxford–AstraZeneca COVID-19 vaccine she co-developed with the Oxford Vaccine Group was approved for use in the UK. As of January 2022, more than 2.5 billion doses of the vaccine have been released to more than 170 countries worldwide. Early life and education Sarah Catherine Gilbert was born in Kettering, Northamptonshire. ...
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Oxford University Innovation
Oxford University Innovation Limited (OUI) is a British technology transfer and Consultant, consultancy company created to manage the research and development (R&D) of University spin-offs. OUI is a wholly owned subsidiary of the University of Oxford, and is located on Botley Road, Oxford, England. OUI was previously known as The Isis, Isis Innovation (1988–2016) and Oxford University Research and Development Ltd (1987–1988). Overview The company was established in 1987 as Oxford University Research and Development Ltd and was renamed Isis Innovation a year later, becoming Oxford University Innovation in 2016. Oxford University Innovation and its sub-divisions manage the university's intellectual property (IP) portfolio, working with University academics and researchers who wish to commercialise their work by identifying, protecting and marketing technologies through patenting and licensing, Corporate spin-off, spin-off company formation, consulting and material sales. Oxford ...
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Jenner Institute
The Jenner Institute is a research institute on the Old Road Campus in Headington, east Oxford, England. It was formed in November 2005 through a partnership between the University of Oxford and the UK Institute for Animal Health. It is associated with the Nuffield Department of Medicine, in the Medical Sciences Division of Oxford University. The institute receives charitable support from the Jenner Vaccine Foundation. The institute is led by Prof. Adrian Hill. The institute develops vaccines and carries out clinical trials for diseases including malaria, tuberculosis (vaccine MVA85A), ebola, and MERS-Coronavirus. In 2020, the institute successfully developed the Oxford–AstraZeneca COVID-19 vaccine, in a project backed by private companies including Oxford Sciences Innovation, Google Ventures, and Sequoia Capital, among others. When developed, the UK government backed trials, purchased 100million does, and encouraged Oxford to work with AstraZeneca, a company based in ...
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Sarah Gilbert (scientist)
Dame Sarah Catherine Gilbert (born April 1962) is an English vaccinologist who is a Professor of Vaccinology at the University of Oxford and co-founder of Vaccitech. She specialises in the development of vaccines against influenza and emerging viral pathogens. She led the development and testing of the universal flu vaccine, which underwent clinical trials in 2011. In January 2020, she read a report on ProMED-mail about four people in China suffering from a strange kind of pneumonia of unknown origin in Wuhan. Within two weeks, a vaccine had been designed at Oxford against the new pathogen, which later became known as COVID-19. On 30 December 2020, the Oxford–AstraZeneca COVID-19 vaccine she co-developed with the Oxford Vaccine Group was approved for use in the UK. As of January 2022, more than 2.5 billion doses of the vaccine have been released to more than 170 countries worldwide. Early life and education Sarah Catherine Gilbert was born in Kettering, Northamptonsh ...
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Public Company
A public company is a company whose ownership is organized via shares of stock which are intended to be freely traded on a stock exchange or in over-the-counter markets. A public (publicly traded) company can be listed on a stock exchange ( listed company), which facilitates the trade of shares, or not ( unlisted public company). In some jurisdictions, public companies over a certain size must be listed on an exchange. In most cases, public companies are ''private'' enterprises in the ''private'' sector, and "public" emphasizes their reporting and trading on the public markets. Public companies are formed within the legal systems of particular states, and therefore have associations and formal designations which are distinct and separate in the polity in which they reside. In the United States, for example, a public company is usually a type of corporation (though a corporation need not be a public company), in the United Kingdom it is usually a public limited company (plc), ...
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Fosun International
Fosun International Limited is a Chinese multinational conglomerate holding company. Founded in 1992 by Guo Guangchang and four others, the company is headquartered in Shanghai and was incorporated in Hong Kong in 2004. Its Co-CEOs are Chen Qiyu and Xu Xiaoliang. Wang Qunbin joined Guo Guangchang as co-chairman in early 2020. The company is located in 16 countries and is one of the largest privately owned conglomerates in China. It was ranked 371st on the Forbes Global 2000 ranking in 2020. History 1990s Fosun Group was founded in 1992 as the Guangxin Technology Development Company by five graduates of Fudan University in Shanghai: Guo Guangchang, Liang Xinjun, Wang Qunbin (), Fan Wei (), and Tan Jian (). Fosun started its business by doing market research. The major holding company of the group, Fosun High Technology, was incorporated in 1994 in mainland China. Then Fosun extended its business into the healthcare industry (as Fosun Pharmaceutical), real estate, and ...
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Google Ventures
GV is a venture capital investment arm of Alphabet Inc., founded by Bill Maris, that provides seed, venture, and growth stage funding to technology companies. Founded as Google Ventures in 2009, the firm has operated independently of Google, Alphabet's search and advertising behemoth, since 2015. GV seeks to invest in startup companies in a variety of fields ranging from the Internet, software, and hardware to life science, healthcare, artificial intelligence, transportation, cyber security and agriculture. History The group was founded on March 31, 2009, with a $100 million capital commitment, by Bill Maris who also became GV's first CEO. In 2012, that commitment was raised to $300 million annually, and the fund has $2 billion under management. In 2014, the group announced $125 million to invest in promising European startups. By 2014, it had invested in companies such as Shape Security. In December 2015, the company was renamed GV and introduced a new logo. As of 2016, GV h ...
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Bloomberg News
Bloomberg News (originally Bloomberg Business News) is an international news agency headquartered in New York City and a division of Bloomberg L.P. Content produced by Bloomberg News is disseminated through Bloomberg Terminals, Bloomberg Television, Bloomberg Radio, ''Bloomberg Businessweek'', ''Bloomberg Markets'', Bloomberg.com, and Bloomberg's mobile platforms. Since 2015, John Micklethwait has served as editor-in-chief. History Bloomberg News was founded by Michael Bloomberg and Matthew Winkler in 1990 to deliver financial news reporting to Bloomberg Terminal subscribers. The agency was established in 1990 with a team of six people. Winkler was first editor-in-chief. In 2010, Bloomberg News included more than 2,300 editors and reporters in 72 countries and 146 news bureaus worldwide. Beginnings (1990–1995) Bloomberg Business News was created to expand the services offered through the terminals. According to Matthew Winkler, then a writer for ''The Wall Street Journal ...
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University Of Oxford
The University of Oxford is a collegiate research university in Oxford, England. There is evidence of teaching as early as 1096, making it the oldest university in the English-speaking world and the world's second-oldest university in continuous operation. It grew rapidly from 1167 when Henry II banned English students from attending the University of Paris. After disputes between students and Oxford townsfolk in 1209, some academics fled north-east to Cambridge where they established what became the University of Cambridge. The two English ancient universities share many common features and are jointly referred to as ''Oxbridge''. Both are ranked among the most prestigious universities in the world. The university is made up of thirty-nine semi-autonomous constituent colleges, five permanent private halls, and a range of academic departments which are organised into four divisions. All the colleges are self-governing institutions within the university, each controlling ...
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University Spin-off
University spin-offs (also known as university spin-outs) are companies that transform technological inventions developed from university research that are likely to remain unexploited otherwise. They are a subcategory of research spin-offs. Prominent examples of university spin-offs are Genentech, Crucell, Lycos and Plastic Logic. In most countries, universities can claim the intellectual property (IP) rights on technologies developed in their laboratories. In the United States, the Bayh–Dole Act permits universities to pursue ownership of inventions made by researchers at their institutions using funding from the federal government, where previously federal research funding contracts and grants obligated inventors (wherever they worked) to assign the resulting IP to the government. This IP typically draws on patents or, in exceptional cases, copyrights. Therefore, the process of establishing the spin-off as a new corporation involves transferring the IP to the new corporation or ...
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Tumour
A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists in growing abnormally, even if the original trigger is removed. This abnormal growth usually forms a mass, when it may be called a tumor. ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of uncertain or unknown behavior. Malignant neoplasms are also simply known as cancers and are the focus of oncology. Prior to the abnormal growth of tissue, as neoplasia, cells often undergo an abnormal pattern of growth, such as metaplasia or dysplasia. However, metaplasia or dysplasia does not always progress to neoplasia and can occur in other conditions as well. The word is from Ancient Greek 'new' and 'formation, creation'. Types A neoplasm can be benign, potenti ...
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Pathogen
In biology, a pathogen ( el, πάθος, "suffering", "passion" and , "producer of") in the oldest and broadest sense, is any organism or agent that can produce disease. A pathogen may also be referred to as an infectious agent, or simply a germ. The term ''pathogen'' came into use in the 1880s. Typically, the term ''pathogen'' is used to describe an ''infectious'' microorganism or agent, such as a virus, bacterium, protozoan, prion, viroid, or fungus. Small animals, such as helminths and insects, can also cause or transmit disease. However, these animals are usually referred to as parasites rather than pathogens. The scientific study of microscopic organisms, including microscopic pathogenic organisms, is called microbiology, while parasitology refers to the scientific study of parasites and the organisms that host them. There are several pathways through which pathogens can invade a host. The principal pathways have different episodic time frames, but soil has the ...
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