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Jenner Institute
The Jenner Institute is a research institute on the Old Road Campus in Headington, east Oxford, England. It was formed in November 2005 through a partnership between the University of Oxford and the UK Institute for Animal Health. It is associated with the Nuffield Department of Medicine, in the Medical Sciences Division of Oxford University. The institute receives charitable support from the Jenner Vaccine Foundation. The institute is led by Prof. Adrian Hill. The institute develops vaccines and carries out clinical trials for diseases including malaria, tuberculosis (vaccine MVA85A), ebola, and MERS-Coronavirus. In 2020, the institute successfully developed the Oxford–AstraZeneca COVID-19 vaccine, in a project backed by private companies including Oxford Sciences Innovation, Google Ventures, and Sequoia Capital, among others. When developed, the UK government backed trials, purchased 100million does, and encouraged Oxford to work with AstraZeneca, a company based in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adrian V
Pope Adrian V (Latin: ''Adrianus V''; c. 1210/1220 – 18 August 1276), born Ottobuono de' Fieschi, was the head of the Catholic Church and ruler of the Papal States from 11 July 1276 to his death on 18 August 1276. He was an envoy of Pope Clement IV sent to England in May 1265 who successfully completed his task of resolving disputes between King Henry III of England and his barons. Adrian V was elected pope following the death of Innocent V, but died of natural illness before being ordained to the priesthood. In the ''Divine Comedy'', Dante meets Adrian V in the fifth terrace of ''Purgatorio'' where Adrian V cleanses for the vice of avarice. Biography Ottobuono belonged to a feudal family of Liguria, the Fieschi, counts of Lavagna. His first clerical position came in 1243, when he was created a papal chaplain. Subsequently, he received several ecclesiastical benefices, becoming archdeacon in Bologna (1244) and Parma (1244/48–1255), canon and chancellor of the cathedral ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxford–AstraZeneca COVID-19 Vaccine
The Oxford–AstraZeneca COVID19 vaccine, sold under the brand names Covishield and Vaxzevria among others, is a viral vector vaccine for prevention of COVID-19. Developed in the United Kingdom by Oxford University and British-Swedish company AstraZeneca, using as a vector the modified chimpanzee adenovirus ChAdOx1. The vaccine is given by intramuscular injection. Studies carried out in 2020 showed that the efficacy of the vaccine is 76.0% at preventing symptomatic COVID-19 beginning at 22 days following the first dose, and 81.3% after the second dose. A study in Scotland found that, for symptomatic COVID-19 infection after the second dose, the vaccine is 81% effective against the Alpha variant (lineage B.1.1.7), and 61% against the Delta variant (lineage B.1.617.2). The vaccine is stable at refrigerator temperatures and has a good safety profile, with side effects including injection-site pain, headache, and nausea, all generally resolving within a few days. More rarely, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edward Jenner
Edward Jenner, (17 May 1749 – 26 January 1823) was a British physician and scientist who pioneered the concept of vaccines, and created the smallpox vaccine, the world's first vaccine. The terms ''vaccine'' and ''vaccination'' are derived from ''Variolae vaccinae'' ('pustules of the cow'), the term devised by Jenner to denote cowpox. He used it in 1798 in the title of his ''Inquiry into the Variolae vaccinae known as the Cow Pox'', in which he described the protective effect of cowpox against smallpox. In the West, Jenner is often called "the father of immunology", and his work is said to have saved "more lives than any other man". In Jenner's time, smallpox killed around 10% of global population, with the number as high as 20% in towns and cities where infection spread more easily. In 1821, he was appointed physician to King George IV of the United Kingdom, George IV, and was also made mayor of Berkeley, Gloucestershire, Berkeley and justice of the peace. A member of the Ro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immunization
Immunization, or immunisation, is the process by which an individual's immune system becomes fortified against an infectious agent (known as the immunogen). When this system is exposed to molecules that are foreign to the body, called ''non-self'', it will orchestrate an immune response, and it will also develop the ability to quickly respond to a subsequent encounter because of immunological memory. This is a function of the adaptive immune system. Therefore, by exposing a human, or an animal, to an immunogen in a controlled way, its body can learn to protect itself: this is called active immunization. The most important elements of the immune system that are improved by immunization are the T cells, B cells, and the antibodies B cells produce. Memory B cells and memory T cells are responsible for a swift response to a second encounter with a foreign molecule. Passive immunization is direct introduction of these elements into the body, instead of production of these elements b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
BBC One
BBC One is a British free-to-air public broadcast television network owned and operated by the BBC. It is the corporation's flagship network and is known for broadcasting mainstream programming, which includes BBC News television bulletins, primetime drama and entertainment, and live BBC Sport events. It was launched on 2 November 1936 as the BBC Television Service and was the world's first regular television service with a high level of image resolution. It was renamed BBC TV in 1960 and used this name until the launch of the second BBC channel, BBC2, in 1964. The main channel then became known as BBC1. The channel adopted the current spelling of BBC One in 1997. The channel's annual budget for 2012–2013 was £1.14 billion. It is funded by the television licence fee together with the BBC's other domestic television stations and shows uninterrupted programming without commercial advertising. The television channel had the highest reach share of any broadcaster in th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Andrew Marr Show
''The Andrew Marr Show'' is a Sunday morning talk show presented by Andrew Marr. It was broadcast on BBC One from 2005 to 2021. The programme replaced the long-running ''Breakfast with Frost'' as the network's flagship Sunday talk show when David Frost decided to retire. Originally launched as ''Sunday AM'', it was renamed ''The Andrew Marr Show'' in September 2007 when the show returned after its summer break. Marr interviewed political figures and others involved in the current events of the week in every episode. The programme begins with a review of the Sunday papers, for which Marr is joined by two or three different guests. It also featured BBC News and BBC Weather updates. The programme shared a studio with ''Sunday Politics'', ''Newsnight'' and ''HARDtalk'', ''BBC World News'', ''GMT'', ''Impact'', ''Global'' and ''Focus on Africa''. Following Marr's departure from the BBC in 2021, the show was broadcast under the temporary title ''Sunday Morning''. Editors included Rob B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Lancet
''The Lancet'' is a weekly peer-reviewed general medical journal and one of the oldest of its kind. It is also the world's highest-impact academic journal. It was founded in England in 1823. The journal publishes original research articles, review articles ("seminars" and "reviews"), editorials, book reviews, correspondence, as well as news features and case reports. ''The Lancet'' has been owned by Elsevier since 1991, and its editor-in-chief since 1995 has been Richard Horton. The journal has editorial offices in London, New York City, and Beijing. History ''The Lancet'' was founded in 1823 by Thomas Wakley, an English surgeon who named it after the surgical instrument called a lancet (scalpel). Members of the Wakley family retained editorship of the journal until 1908. In 1921, ''The Lancet'' was acquired by Hodder & Stoughton. Elsevier acquired ''The Lancet'' from Hodder & Stoughton in 1991. Impact According to the ''Journal Citation Reports'', the journal has a 202 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sarah Gilbert
Dame Sarah Catherine Gilbert (born April 1962) is an English vaccinologist who is a Professor of Vaccinology at the University of Oxford and co-founder of Vaccitech. She specialises in the development of vaccines against influenza and emerging viral pathogens. She led the development and testing of the universal flu vaccine, which underwent clinical trials in 2011. In January 2020, she read a report on ProMED-mail about four people in China suffering from a strange kind of pneumonia of unknown origin in Wuhan. Within two weeks, a vaccine had been designed at Oxford against the new pathogen, which later became known as COVID-19. On 30 December 2020, the Oxford–AstraZeneca COVID-19 vaccine she co-developed with the Oxford Vaccine Group was approved for use in the UK. As of January 2022, more than 2.5 billion doses of the vaccine have been released to more than 170 countries worldwide. Early life and education Sarah Catherine Gilbert was born in Kettering, Northamptonshire ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
COVID-19 Vaccine
A COVID19 vaccine is a vaccine intended to provide acquired immunity against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), the virus that causes coronavirus disease 2019 ( COVID19). Prior to the COVID19 pandemic, an established body of knowledge existed about the structure and function of coronaviruses causing diseases like severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). This knowledge accelerated the development of various vaccine platforms during early 2020. The initial focus of SARS-CoV-2 vaccines was on preventing symptomatic, often severe illness. In January 2020, the SARS-CoV-2 genetic sequence data was shared through GISAID, and by March 2020, the global pharmaceutical industry announced a major commitment to address COVID19. In 2020, the first COVID19 vaccines were developed and made available to the public through emergency authorizations and conditional approvals. Initially, most COVID19 vaccines were two ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Merck Group
The Merck Group, branded and commonly known as Merck, is a German multinational science and technology company headquartered in Darmstadt, with about 60,000 employees and present in 66 countries. The group includes around 250 companies; the main company is Merck KGaA in Germany. The company is divided into three business lines: Healthcare, Life Sciences and Electronics. Merck was founded in 1668 and is the world's oldest operating chemical and pharmaceutical company, as well as one of the largest pharmaceutical companies in the world. Merck operates in Europe, Africa, Asia, Oceania and the Americas. It has major research and development centres in Darmstadt, Boston, Tokyo and Beijing, as well as other Research and Development units in Taiwan, France, Israel, South Korea, India and in the UK. Merck pioneered the commercial manufacture of morphine in the 19th century and for a time held a virtual monopoly on cocaine. Merck was privately owned until going public on the Frankfu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Merck & Co
Merck & Co., Inc. is an American multinational pharmaceutical company headquartered in Rahway, New Jersey, and is named for Merck Group, founded in Germany in 1668, of whom it was once the American arm. The company does business as Merck Sharp & Dohme or MSD outside the United States and Canada. Merck & Co. was originally established as the American affiliate of Merck Group in 1891. Merck develops and produces medicines, vaccines, biologic therapies and animal health products. It has multiple blockbuster drugs or products each with 2020 revenues including cancer immunotherapy, anti-diabetic medication and vaccines against HPV and chickenpox. The company is ranked 71st on the 2022 ''Fortune'' 500 and 87th on the 2022 ''Forbes'' Global 2000, both based on 2021 revenues. Products The company develops medicines, vaccines, biologic therapies and animal health products. In 2020, the company had 6 blockbuster drugs or products, each with over $1 billion in revenue: ''Keytruda'' ( ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UK Government
ga, Rialtas a Shoilse gd, Riaghaltas a Mhòrachd , image = HM Government logo.svg , image_size = 220px , image2 = Royal Coat of Arms of the United Kingdom (HM Government).svg , image_size2 = 180px , caption = Royal Arms , date_established = , state = United Kingdom , address = 10 Downing Street, London , leader_title = Prime Minister (Rishi Sunak) , appointed = Monarch of the United Kingdom (Charles III) , budget = 882 billion , main_organ = Cabinet of the United Kingdom , ministries = 23 ministerial departments, 20 non-ministerial departments , responsible = Parliament of the United Kingdom , url = The Government of the United Kingdom (commonly referred to as British Government or UK Government), officially His Majesty's Government (abbreviated to HM Government), is the central executive authority of the United Kingdom of Great Britain and Northern Ireland. [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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