Sir James Mackenzie
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Sir James Mackenzie
Sir James Mackenzie (12 April 1853 – 26 January 1925) was a Scottish cardiologist who was a pioneer in the study of cardiac arrhythmias. Due to his work in the cardiac field he is known as a research giant in primary care, and was knighted by King George V in 1915. Biography James Mackenzie was born at Pictonhill in Scone, where his father was a farmer. He left school at Perth Academy aged 14 and was apprenticed to a chemist. In 1873 he was offered a partnership in the chemist's firm but turned it down in order to study medicine. After private tuition in Latin he passed his entrance examination for the University of Edinburgh in October 1874 and qualified as a doctor in 1878. After completing his residency in Edinburgh, Mackenzie became a general practitioner in borough of Burnley in Lancashire, England where he continued to practice medicine for more than a quarter of a century. While he was engaged in a busy practice, he made many original observations, completed his MD deg ...
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Scone, Scotland
Scone (; gd, Sgàin; sco, Scuin) is a town in Perth and Kinross, Scotland. The medieval town of Scone, which grew up around the monastery and royal residence, was abandoned in the early 19th century when the residents were removed and a new palace was built on the site by the Earl of Mansfield. Hence the modern village of Scone, and the medieval village of Old Scone, can often be distinguished. Both sites lie in the historical province of Gowrie, as well as the old county of Perthshire. Old Scone was the historic capital of the Kingdom of Scotland. In the Middle Ages it was an important royal centre, used as a royal residence and as the coronation site of the kingdom's monarchs. Around the royal site grew the town of Perth and the Abbey of Scone. Scone and Scotland Scone's association with kings and king-making gave it various epithets in Gaelic poetry; for instance, ''Scoine sciath-airde'', "Scone of the High Shields", and ', "Scone of the Noisy Shields". Scotland its ...
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Sphygmograph
The sphygmograph ( ) was a mechanical device used to measure blood pressure in the mid-19th century. It was developed in 1854 by German physiologist Karl von Vierordt (1818–1884). It is considered the first external, non-intrusive device used to estimate blood pressure. The device was a system of levers hooked to a scale-pan in which weights were placed to determine the amount of external pressure needed to stop blood flow in the radial artery. Although the instrument was cumbersome and its measurements imprecise, the basic concept of Vierordt's sphygmograph eventually led to the blood pressure cuff used today. In 1863, Étienne-Jules Marey (1830–1904) improved the device by making it portable. Also he included a specialized instrument to be placed above the radial artery that was able to magnify pulse waves and record them on paper with an attached pen. In 1872, Frederick Akbar Mahomed published a description of a modified sphygmograph. This modified version made the sphygmo ...
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Myocardial Infarction
A myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops to the coronary artery of the heart, causing damage to the heart muscle. The most common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck or jaw. Often it occurs in the center or left side of the chest and lasts for more than a few minutes. The discomfort may occasionally feel like heartburn. Other symptoms may include shortness of breath, nausea, feeling faint, a cold sweat or feeling tired. About 30% of people have atypical symptoms. Women more often present without chest pain and instead have neck pain, arm pain or feel tired. Among those over 75 years old, about 5% have had an MI with little or no history of symptoms. An MI may cause heart failure, an irregular heartbeat, cardiogenic shock or cardiac arrest. Most MIs occur due to coronary artery disease. Risk factors include high blood pressure, smoking, diabetes, ...
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Coronary Artery Disease
Coronary artery disease (CAD), also called coronary heart disease (CHD), ischemic heart disease (IHD), myocardial ischemia, or simply heart disease, involves the reduction of blood flow to the heart muscle due to build-up of atherosclerotic plaque An atheroma, or atheromatous plaque, is an abnormal and reversible accumulation of material in the inner layer of an arterial wall. The material consists of mostly macrophage cells, or debris, containing lipids, calcium and a variable amount ... in the arteries of the heart. It is the most common of the cardiovascular diseases. Types include stable angina, unstable angina, myocardial infarction, and sudden cardiac death. A common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Occasionally it may feel like heartburn. Usually symptoms occur with exercise or emotional Stress (psychological), stress, last less than a few minutes, and improve with rest. Shortness of breath may also o ...
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Sir Thomas Lewis
Sir Thomas Lewis, CBE, FRS, FRCP (26 December 1881 – 17 March 1945) was a British cardiologist (although he personally disliked the term, preferring cardiovascular disease specialist). He coined the term "clinical science".Biography, ''Oxford Dictionary of National Biography'' Early life and education Lewis was born in Taffs Well, Cardiff, Wales, the son of Henry Lewis, a mining engineer, and his wife Catherine Hannah (née Davies). He was educated at home by his mother, apart from a year at Clifton College, which he left due to ill-health, and the final two years by a tutor. Already planning to become a doctor, at the age of sixteen he began a Bachelor of Science (BSc) course at University College, Cardiff, graduating three years later with first class honours. In 1902 he entered University College Hospital in London to train as a doctor, graduating MBBS with the gold medal in 1905. The same year he was awarded a Doctor of Science (DSc) degree from the University of Wales fo ...
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Angina Pectoris
Angina, also known as angina pectoris, is chest pain or pressure, usually caused by insufficient blood flow to the heart muscle (myocardium). It is most commonly a symptom of coronary artery disease. Angina is typically the result of obstruction or spasm of the arteries that supply blood to the heart muscle. The main mechanism of coronary artery obstruction is atherosclerosis as part of coronary artery disease. Other causes of angina include abnormal heart rhythms, heart failure and, less commonly, anemia. The term derives from the Latin ''angere'' ("to strangle") and ''pectus'' ("chest"), and can therefore be translated as "a strangling feeling in the chest". There is a weak relationship between severity of angina and degree of oxygen deprivation in the heart muscle, however, the severity of angina does not always match the degree of oxygen deprivation to the heart or the risk of a myocardial infarction (heart attack). Some people may experience severe pain even though the ...
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Ischemic Heart Disease
Coronary artery disease (CAD), also called coronary heart disease (CHD), ischemic heart disease (IHD), myocardial ischemia, or simply heart disease, involves the reduction of blood flow to the heart muscle due to build-up of atherosclerotic plaque in the arteries of the heart. It is the most common of the cardiovascular diseases. Types include stable angina, unstable angina, myocardial infarction, and sudden cardiac death. A common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Occasionally it may feel like heartburn. Usually symptoms occur with exercise or emotional stress, last less than a few minutes, and improve with rest. Shortness of breath may also occur and sometimes no symptoms are present. In many cases, the first sign is a heart attack. Other complications include heart failure or an abnormal heartbeat. Risk factors include high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, po ...
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Knight
A knight is a person granted an honorary title of knighthood by a head of state (including the Pope) or representative for service to the monarch, the church or the country, especially in a military capacity. Knighthood finds origins in the Greek ''hippeis'' and '' hoplite'' (ἱππεῖς) and Roman '' eques'' and ''centurion'' of classical antiquity. In the Early Middle Ages in Europe, knighthood was conferred upon mounted warriors. During the High Middle Ages, knighthood was considered a class of lower nobility. By the Late Middle Ages, the rank had become associated with the ideals of chivalry, a code of conduct for the perfect courtly Christian warrior. Often, a knight was a vassal who served as an elite fighter or a bodyguard for a lord, with payment in the form of land holdings. The lords trusted the knights, who were skilled in battle on horseback. Knighthood in the Middle Ages was closely linked with horsemanship (and especially the joust) from its origins in th ...
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Fellow Of The Royal Society
Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the judges of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural science, natural knowledge, including mathematics, engineering science, and medical science". Fellow, Fellowship of the Society, the oldest known scientific academy in continuous existence, is a significant honour. It has been awarded to many eminent scientists throughout history, including Isaac Newton (1672), Michael Faraday (1824), Charles Darwin (1839), Ernest Rutherford (1903), Srinivasa Ramanujan (1918), Albert Einstein (1921), Paul Dirac (1930), Winston Churchill (1941), Subrahmanyan Chandrasekhar (1944), Dorothy Hodgkin (1947), Alan Turing (1951), Lise Meitner (1955) and Francis Crick (1959). More recently, fellowship has been awarded to Stephen Hawking (1974), David Attenborough (1983), Tim Hunt (1991), Elizabeth Blackburn (1992), Tim Berners-Lee (2001), Venki R ...
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Digitalis
''Digitalis'' ( or ) is a genus of about 20 species of herbaceous perennial plants, shrubs, and biennials, commonly called foxgloves. ''Digitalis'' is native to Europe, western Asia, and northwestern Africa. The flowers are tubular in shape, produced on a tall spike, and vary in colour with species, from purple to pink, white, and yellow. The scientific name means "finger". The genus was traditionally placed in the figwort family, Scrophulariaceae, but phylogenetic research led taxonomists to move it to the Veronicaceae in 2001. More recent phylogenetic work has placed it in the much enlarged family Plantaginaceae. The best-known species is the common foxglove, ''Digitalis purpurea''. This biennial is often grown as an ornamental plant due to its vivid flowers which range in colour from various purple tints through pink and purely white. The flowers can also possess various marks and spottings. Other garden-worthy species include ''D. ferruginea'', ''D. grandiflora'', ''D. ...
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Atrioventricular Node
The atrioventricular node or AV node electrically connects the heart's atria and ventricles to coordinate beating in the top of the heart; it is part of the electrical conduction system of the heart. The AV node lies at the lower back section of the interatrial septum near the opening of the coronary sinus, and conducts the normal electrical impulse from the atria to the ventricles. The AV node is quite compact (~1 x 3 x 5 mm).Full Size Picture triangle of-Koch.jpg
Retrieved on 2008-12-22


Structure


Location

The AV node lies at the lower back section of the