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Seahorse Bioscience
Seahorse Bioscience is a private company that develops and manufactures cellular bioenergetics analytical instruments. Seahorse also manufactures consumable labware products, and consumables for measuring cell metabolism. The company was formerly known as Thermogenic Imaging. Recognized for developing novel, leading-edge cellular bioenergetic technologies, the company is best known for developing the XF Extracellular Flux Analyzer. XF technology makes cellular bioenergetic studies simple, efficient and user-friendly by combining an electro-optical instrument with ‘smart plastic’ cartridges that enable the real-time measurement of cellular bioenergetics in a non-invasive, multi-well microplate format. The first in vitro metabolic measurement, XF technology non-invasively profiles the metabolic activity of cells in minutes, offering scientists a physiologic cell-based assay for the determination of basal oxygen consumption, glycolysis rates, ATP production, and respiratory ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
North Billerica, Massachusetts
North Billerica is an unincorporated village of the town of Billerica, Massachusetts, United States, one of the nine sections (hamlets) that make up the Town of Billerica. It is the home to Faulkner and Talbot mills and the North Billerica Train Depot. The Middlesex Canal was built through the village in 1783 and the Boston and Lowell Railroad was put through in the 1840s. North Billerica has its own ZIP Code (01862) and post office which also takes in the village of West Billerica and parts of River Pines. History In the late 19th and early 20th centuries, there was a building on Station Street, next to the depot, that served as the North Fire Station, Town Hall Annex, and Post Office. The building was called Union Hall. It served North Billerica as the local Social Club with dances and shows being held on the second floor. It closed down in the 1960s after the Fire Station was relocated a mile away to Lowell Street and the Town Hall Annex was closed. The Post Office ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Agilent Technologies
Agilent Technologies, Inc. is an American life sciences company that provides instruments, software, services, and consumables for the entire laboratory workflow. Its global headquarters is located in Santa Clara, California. Agilent was established in 1999 as a spin-off from Hewlett-Packard. The resulting IPO of Agilent stock was the largest in the history of Silicon Valley at the time. Agilent focuses its products and services on six markets: food, environmental and forensics, pharmaceutical, diagnostics, chemicals and advanced materials, and research. From 1999 to 2014, the company also produced test and measurement equipment for electronics; that division was spun off to form Keysight. Products and services Agilent serves analytical laboratories and the clinical and routine diagnostics markets with a full suite of technology platforms. These include: automation, bioreagents, FISH probes, gas and liquid chromatography, immunohistochemistry, informatics, mass spectrometry ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
FLIR Systems Inc
Forward-looking infrared (FLIR) cameras, typically used on military and civilian aircraft, use a thermographic camera that senses infrared radiation. The sensors installed in forward-looking infrared cameras, as well as those of other thermal imaging cameras, use detection of infrared radiation, typically emitted from a heat source (thermal radiation), to create an image assembled for video output. They can be used to help pilots and drivers steer their vehicles at night and in fog, or to detect warm objects against a cooler background. The wavelength of infrared that thermal imaging cameras detect is 3 to 12 μm and differs significantly from that of night vision, which operates in the visible light and near-infrared ranges (0.4 to 1.0 μm). Design Infrared light falls into two basic ranges: ''long-wave'' and ''medium-wave''. Long-wave infrared (LWIR) cameras, sometimes called "far-infrared", operate at 8 to 12 μm and can see heat sources, such as hot ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurodegenerative Diseases
A neurodegenerative disease is caused by the progressive loss of structure or function of neurons, in the process known as neurodegeneration. Such neuronal damage may ultimately involve cell death. Neurodegenerative diseases include amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease, multiple system atrophy, and prion diseases. Neurodegeneration can be found in the brain at many different levels of neuronal circuitry, ranging from molecular to systemic. Because there is no known way to reverse the progressive degeneration of neurons, these diseases are considered to be incurable; however research has shown that the two major contributing factors to neurodegeneration are oxidative stress and inflammation. Biomedical research has revealed many similarities between these diseases at the subcellular level, including atypical protein assemblies (like proteinopathy) and induced cell death. These similarities suggest tha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity or excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. In the developing world, 15% of cancers are due to infections such as ''Helicobacter pylori'', hepatitis B, hepatitis C, human papillomavirus infection, Epstein–Barr virus and human immunodeficiency virus (HIV). These factors act, at least partly, by changing the genes of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diabetes
Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level ( hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased appetite. If left untreated, diabetes can cause many health complications. Acute complications can include diabetic ketoacidosis, hyperosmolar hyperglycemic state, or death. Serious long-term complications include cardiovascular disease, stroke, chronic kidney disease, foot ulcers, damage to the nerves, damage to the eyes, and cognitive impairment. Diabetes is due to either the pancreas not producing enough insulin, or the cells of the body not responding properly to the insulin produced. Insulin is a hormone which is responsible for helping glucose from food get into cells to be used for energy. There are three main types of diabetes mellitus: * Type 1 diabetes results from failure of the pancreas to produce enough insulin due ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Obesity
Obesity is a medical condition, sometimes considered a disease, in which excess body fat has accumulated to such an extent that it may negatively affect health. People are classified as obese when their body mass index (BMI)—a person's weight divided by the square of the person's height—is over ; the range is defined as overweight. Some East Asian countries use lower values to calculate obesity. Obesity is a major cause of disability and is correlated with various diseases and conditions, particularly cardiovascular diseases, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and osteoarthritis. Obesity has individual, socioeconomic, and environmental causes. Some known causes are diet, physical activity, automation, urbanization, genetic susceptibility, medications, mental disorders, economic policies, endocrine disorders, and exposure to endocrine-disrupting chemicals. While a majority of obese individuals at any given time are attemptin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drug Manufacturing
Pharmaceutical manufacturing is the process of industrial-scale organic synthesis, synthesis of pharmaceutical drugs as part of the pharmaceutical industry. The process of drug manufacturing can be broken down into a series of unit operations, such as mill (grinding), milling, Granulation (process), granulation, Coated tablet, coating, tablet pressing, and others. Scale-up considerations Cooling While a laboratory may use dry ice as a cooling agent for reaction selectivity, this process gets complicated on an industrial scale. The cost to cool a typical reactor to this temperature is large, and the viscosity of the reagents typically also increases as the temperature lowers, leading to difficult mixing. This results in added costs to stir harder and replace parts more often, or it results in a non-homogeneous reaction. Finally, lower temperatures can result in crusting of reagents, intermediates, and byproducts to the reaction vessel over time, which will impact the purity of th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Denmark
) , song = ( en, "King Christian stood by the lofty mast") , song_type = National and royal anthem , image_map = EU-Denmark.svg , map_caption = , subdivision_type = Sovereign state , subdivision_name = Kingdom of Denmark , established_title = Consolidation , established_date = 8th century , established_title2 = Christianization , established_date2 = 965 , established_title3 = , established_date3 = 5 June 1849 , established_title4 = Faroese home rule , established_date4 = 24 March 1948 , established_title5 = EEC accession , established_date5 = 1 January 1973 , established_title6 = Greenlandic home rule , established_date6 = 1 May 1979 , official_languages = Danish , languages_type = Regional languages , languages_sub = yes , languages = GermanGerman is recognised as a protected minority language in the South Jutland area of Denmark. , demonym = , capital = Copenhagen , largest_city = capital , coordinates = , ethnic_groups = , ethnic_g ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bioscience
''BioScience'' is a monthly peer-reviewed scientific journal that is published by Oxford University Press on behalf of the American Institute of Biological Sciences. It was established in 1964 and was preceded by the ''AIBS Bulletin'' (1951–1963). The journal publishes literature reviews of current research in biology, as well as essays and discussion sections on education, public policy, history of biology, and theoretical issues. Abstracting and indexing The journal is abstracted and indexed in MEDLINE/PubMed (1973–1979), the Science Citation Index, Current Contents/Agriculture, Biology & Environmental Sciences, The Zoological Record, and BIOSIS Previews. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor of 8.589. References External links * {{Official website, http://bioscience.oxfordjournals.org/ Journal pageat the American Institute of Biological Sciences The American Institute of Biological Sciences (AIBS) is a nonprofit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Copenhagen
Copenhagen ( or .; da, København ) is the capital and most populous city of Denmark, with a proper population of around 815.000 in the last quarter of 2022; and some 1.370,000 in the urban area; and the wider Copenhagen metropolitan area has 2,057,142 people. Copenhagen is on the islands of Zealand and Amager, separated from Malmö, Sweden, by the Øresund strait. The Øresund Bridge connects the two cities by rail and road. Originally a Viking fishing village established in the 10th century in the vicinity of what is now Gammel Strand, Copenhagen became the capital of Denmark in the early 15th century. Beginning in the 17th century, it consolidated its position as a regional centre of power with its institutions, defences, and armed forces. During the Renaissance the city served as the de facto capital of the Kalmar Union, being the seat of monarchy, governing the majority of the present day Nordic region in a personal union with Sweden and Norway ruled by th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
China
China, officially the People's Republic of China (PRC), is a country in East Asia. It is the world's most populous country, with a population exceeding 1.4 billion, slightly ahead of India. China spans the equivalent of five time zones and borders fourteen countries by land, the most of any country in the world, tied with Russia. Covering an area of approximately , it is the world's third largest country by total land area. The country consists of 22 provinces, five autonomous regions, four municipalities, and two Special Administrative Regions (Hong Kong and Macau). The national capital is Beijing, and the most populous city and financial center is Shanghai. Modern Chinese trace their origins to a cradle of civilization in the fertile basin of the Yellow River in the North China Plain. The semi-legendary Xia dynasty in the 21st century BCE and the well-attested Shang and Zhou dynasties developed a bureaucratic political system to serve hereditary monarchies, or ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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