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Shyamala Gopalan
Gopalan Shyamala (December 7, 1938 – February 11, 2009) was a biomedical scientist at the Lawrence Berkeley National Laboratory, whose work in isolating and characterizing the progesterone receptor gene stimulated advances in breast biology and oncology. She was the mother of Vice President of the United States Kamala Harris and Maya Harris, a lawyer and political commentator. Early life and education Shyamala was born on December 7, 1938, in Madras, Madras Province, British India (present-day Chennai, Tamil Nadu, India) to Rajam Gopalan and P. V. Gopalan, a civil servant. Her parents were from two villages near the town of Mannargudi in Madras Province. According to ''The Los Angeles Times'', "Gopalan was a Tamil Brahmin, part of a privileged elite in Hinduism’s ancient caste hierarchy". According to Shyamala's brother, Balachandran, their parents were broad-minded in raising the children, all of whom led somewhat unconventional lives. Gopalan began his professional ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Madras
Chennai (, ), formerly known as Madras ( the official name until 1996), is the capital city of Tamil Nadu, the southernmost Indian state. The largest city of the state in area and population, Chennai is located on the Coromandel Coast of the Bay of Bengal. According to the 2011 Indian census, Chennai is the sixth-most populous city in the country and forms the fourth-most populous urban agglomeration. The Greater Chennai Corporation is the civic body responsible for the city; it is the oldest city corporation of India, established in 1688—the second oldest in the world after London. The city of Chennai is coterminous with Chennai district, which together with the adjoining suburbs constitutes the Chennai Metropolitan Area, the List of urban areas by population, 36th-largest urban area in the world by population and one of the largest metropolitan economies of India. The traditional and de facto gateway of South India, Chennai is among the most-visited Indian cities by f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lady Davis Institute For Medical Research
The Jewish General Hospital (JGH; french: Hôpital général juif), known officially as the Sir Mortimer B. Davis Jewish General Hospital (french: Hôpital général juif Sir Mortimer B. Davis) since 1978, is an acute-care teaching hospital in Montreal, Quebec, Canada. The hospital is affiliated with McGill University and has 637 beds, one of the most of a hospital site in Canada. In 2019, Newsweek ranked the hospital 4th in Canada and 1st in Quebec. History The Jewish General Hospital, which opened its doors in 1934, was founded as a general hospital, open to all patients regardless of race, religion, language or ethnic background. It was founded by the Jewish community of Montreal in part as a response to the anti-Semitic "Days of Shame" doctor's strike at the Hôpital Notre-Dame in Montreal, Quebec, Canada where all interns at the hospital walked off the job for four days to protest the hiring of a Jewish senior intern, Dr. Samuel Rabinovitch and then only returned to work a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Calcutta
Kolkata (, or , ; also known as Calcutta , List of renamed places in India#West Bengal, the official name until 2001) is the Capital city, capital of the Indian States and union territories of India, state of West Bengal, on the eastern bank of the Hooghly River west of the border with Bangladesh. It is the primary business, commercial, and financial hub of East India, Eastern India and the main port of communication for North-East India. According to the 2011 Indian census, Kolkata is the List of cities in India by population, seventh-most populous city in India, with a population of 45 lakh (4.5 million) residents within the city limits, and a population of over 1.41 crore (14.1 million) residents in the Kolkata metropolitan area, Kolkata Metropolitan Area. It is the List of metropolitan areas in India, third-most populous metropolitan area in India. In 2021, the Kolkata metropolitan area crossed 1.5 crore (15 million) registered voters. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bombay
Mumbai (, ; also known as Bombay — the official name until 1995) is the capital city of the Indian state of Maharashtra and the ''de facto'' financial centre of India. According to the United Nations, as of 2018, Mumbai is the second-most populous city in India after Delhi and the eighth-most populous city in the world with a population of roughly 20 million (2 crore). As per the Indian government population census of 2011, Mumbai was the most populous city in India with an estimated city proper population of 12.5 million (1.25 crore) living under the Brihanmumbai Municipal Corporation. Mumbai is the centre of the Mumbai Metropolitan Region, the sixth most populous metropolitan area in the world with a population of over 23 million (2.3 crore). Mumbai lies on the Konkan coast on the west coast of India and has a deep natural harbour. In 2008, Mumbai was named an alpha world city. It has the highest number of millionaires and billionaires among all cities i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New Delhi
New Delhi (, , ''Naī Dillī'') is the capital of India and a part of the National Capital Territory of Delhi (NCT). New Delhi is the seat of all three branches of the government of India, hosting the Rashtrapati Bhavan, Parliament House, and the Supreme Court of India. New Delhi is a municipality within the NCT, administered by the NDMC, which covers mostly Lutyens' Delhi and a few adjacent areas. The municipal area is part of a larger administrative district, the New Delhi district. Although colloquially ''Delhi'' and ''New Delhi'' are used interchangeably to refer to the National Capital Territory of Delhi, both are distinct entities, with both the municipality and the New Delhi district forming a relatively small part of the megacity of Delhi. The National Capital Region is a much larger entity comprising the entire NCT along with adjoining districts in neighbouring states, including Ghaziabad, Noida, Gurgaon and Faridabad. The foundation stone of New Delhi was l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tamil Brahmin
Tamil Brahmins are an ethnoreligious community of Tamil-speaking Hindu Brahmins, predominantly living in Tamil Nadu, though they number significantly in Telangana, Andhra Pradesh, Kerala, Karnataka, in addition to other regions of India, as well as Sri Lanka. They can be broadly divided into two denominations: Iyengars, who are adherents of Sri Vaishnavism, and Iyers, who follow the Srauta and Smarta traditions. Denominations Tamil Brahmins are divided into two major denominations: Iyers, who follow the Smartha tradition, and Iyengars, who adhere to the tradition of Sri Vaishnavism. Iyer Iyers are '' Srauta-Smartha'' Brahmins, whose members follow the ''Advaita'' philosophy propounded by Adi Shankara. They are concentrated mainly along the Cauvery Delta districts of Nagapattinam, Thanjavur, Tiruvarur and Tiruchirapalli where they form almost 10% of the total population. However the largest population reside in Nagercoil, making up to 13% of the city's population. G. S. G ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Madras Province
The Madras Presidency, or the Presidency of Fort St. George, also known as Madras Province, was an administrative subdivision (presidency) of British India. At its greatest extent, the presidency included most of southern India, including the whole of the Indian states of Tamil Nadu, Andhra state and some parts of Kerala, Karnataka, Odisha and the union territory of Lakshadweep. The city of Madras was the winter capital of the Presidency and Ootacamund or Ooty, the summer capital. The coastal regions and northern part of Island of Ceylon at that time was a part of Madras Presidency from 1793 to 1798 when it was created a Crown colony. Madras Presidency was neighboured by the Kingdom of Mysore on the northwest, Kingdom of Cochin on the southwest, and the Kingdom of Hyderabad on the north. Some parts of the presidency were also flanked by Bombay Presidency (Konkan) and Central Provinces and Berar (Madhya Pradesh). In 1639, the English East India Company purchased the villa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mannargudi
Mannargudi () is a town in Thiruvarur district in the Indian state of Tamil Nadu. It is the headquarters of the Mannargudi taluk. The town is located at a distance of from the district headquarters Thiruvarur, 36 km from Kumbakonam, 40 km from Thanjavur and from the state capital Chennai. Mannargudi is known for the Rajagopalaswamy temple, a prominent Vaishnavite shrine. Mannargudi was founded as an ''agraharam'' village by the Medieval Cholas during the 7th century A.D. The town was subsequently ruled by various dynasties including the Chola king Rajadhiraja Chola (1018–1054 CE), Vijayanagar Empire, Delhi Sultanate, Thanjavur Nayaks, Thanjavur Marathas and the British Empire. Mannargudi was a part of the erstwhile Tanjore district until India's independence in 1947 and Thanjavur district until 1991. It subsequently became a part of the newly formed Tiruvarur district. The town is known for agriculture, metal working and weaving. The region around Mannargudi has considerab ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vice President Of The United States
The vice president of the United States (VPOTUS) is the second-highest officer in the executive branch of the U.S. federal government, after the president of the United States, and ranks first in the presidential line of succession. The vice president is also an officer in the legislative branch, as the president of the Senate. In this capacity, the vice president is empowered to preside over Senate deliberations at any time, but may not vote except to cast a tie-breaking vote. The vice president is indirectly elected together with the president to a four-year term of office by the people of the United States through the Electoral College. The modern vice presidency is a position of significant power and is widely seen as an integral part of a president's administration. While the exact nature of the role varies in each administration, most modern vice presidents serve as a key presidential advisor, governing partner, and representative of the president. The vice president ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oncology
Oncology is a branch of medicine that deals with the study, treatment, diagnosis and prevention of cancer. A medical professional who practices oncology is an ''oncologist''. The name's etymological origin is the Greek word ὄγκος (''ónkos''), meaning "tumor", "volume" or "mass". Oncology is concerned with: * The diagnosis of any cancer in a person (pathology) * Therapy (e.g. surgery, chemotherapy, radiotherapy and other modalities) * Follow-up of cancer patients after successful treatment * Palliative care of patients with terminal malignancies * Ethical questions surrounding cancer care * Screening efforts: ** of populations, or ** of the relatives of patients (in types of cancer that are thought to have a hereditary basis, such as breast cancer) Diagnosis Medical histories remain an important screening tool: the character of the complaints and nonspecific symptoms (such as fatigue, weight loss, unexplained anemia, fever of unknown origin, paraneoplastic phenome ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Progesterone Receptor
The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells. It is activated by the steroid hormone progesterone. In humans, PR is encoded by a single ''PGR'' gene residing on chromosome 11q22, it has two isoforms, PR-A and PR-B, that differ in their molecular weight. The PR-B is the positive regulator of the effects of progesterone, while PR-A serve to antagonize the effects of PR-B. Mechanism Progesterone is necessary to induce the progesterone receptors. When no binding hormone is present the carboxyl terminal inhibits transcription. Binding to a hormone induces a structural change that removes the inhibitory action. Progesterone antagonists prevent the structural reconfiguration. After progesterone binds to the receptor, restructuring with dimerization follows and the complex enters the nucleus and binds to DNA. There transcription takes place, resulting in formation of messenger RNA that is tra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
