Seiichiro Tarui
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Seiichiro Tarui
is a Japanese physician and metabolic disorder researcher. He received the Uehara Award in 1990 while working as a professor at the University of Osaka. He also received the Takeda Medical Science Prize in 1995. Biography Seiichiro Tarui was born in Kōshien, Nishinomiya, Hyōgo Prefecture. He qualified in medicine at the University of Osaka in 1953. From 1959 he was an assistant in the Second Department of Internal Medicine at this university, where he conducted clinical research on disorders of carbohydrate metabolism. He was appointed as Associate Professor of Internal Medicine in 1966, and in 1978 he was elevated to the chair of internal medicine. He retired with emeritus status in 1991. He then became Director of Otemae Hospital, Osaka. Associated eponyms Tarui's disease – An inborn error of glycogen metabolism Metabolism (, from el, μεταβολή ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main function ...
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Japanese Person
The are an East Asian ethnic group native to the Japanese archipelago."人類学上は,旧石器時代あるいは縄文時代以来,現在の北海道〜沖縄諸島(南西諸島)に住んだ集団を祖先にもつ人々。" () Japanese people constitute 97.9% of the population of the country of Japan. Worldwide, approximately 129 million people are of Japanese descent; of these, approximately 122.5 million are residents of Japan. People of Japanese ancestry who live outside Japan are referred to as , the Japanese diaspora. Depending on the context, the term may be limited or not to mainland Japanese people, specifically the Yamato (as opposed to Ryukyuan and Ainu people). Japanese people are one of the largest ethnic groups in the world. In recent decades, there has also been an increase in the number of multiracial people with both Japanese and non-Japanese roots, including half Japanese people. History Theories of origins Archaeological evidence in ...
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Physician
A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the study, diagnosis, prognosis and treatment of disease, injury, and other physical and mental impairments. Physicians may focus their practice on certain disease categories, types of patients, and methods of treatment—known as specialities—or they may assume responsibility for the provision of continuing and comprehensive medical care to individuals, families, and communities—known as general practice. Medical practice properly requires both a detailed knowledge of the academic disciplines, such as anatomy and physiology, underlying diseases and their treatment—the ''science'' of medicine—and also a decent competence in its applied practice—the art or ''craft'' of medicine. Both the role of the physician and the meaning ...
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Metabolic Disorder
A metabolic disorder is a disorder that negatively alters the body's processing and distribution of macronutrients, such as proteins, fats, and carbohydrates. Metabolic disorders can happen when abnormal chemical reactions in the body alter the normal metabolic process. It can also be defined as inherited single gene anomaly, most of which are autosomal recessive. Signs and symptoms Some of the symptoms that can occur with metabolic disorders are lethargy, weight loss, jaundice and seizures. The symptoms expressed would vary with the type of metabolic disorder. There are four categories of symptoms: acute symptoms, late-onset acute symptoms, progressive general symptoms and permanent symptoms. Causes Inherited metabolic disorders are one cause of metabolic disorders, and occur when a defective gene causes an enzyme deficiency. These diseases, of which there are many subtypes, are known as inborn errors of metabolism. Metabolic diseases can also occur when the liver or pancre ...
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Uehara Award
Uehara (written: lit. "upper plain" or lit. "planted plain") is a Japanese surname. In Okinawan language, it's pronounced as 'Wiibaru. Notable people with the surname include: *, Japanese golfer *, Japanese classical pianist *, Japanese singer *, Japanese singer and soldier *Edwin Uehara (born 1969), Peruvian-Japanese footballer *, politician and cabinet minister *, Japanese musician *, Japanese jazz composer and pianist *, Japanese actor *, Japanese manga artist *, Japanese fencer *Koichi Uehara (born 1947), Japanese golfer *, Japanese baseball player *, Japanese kickboxer *, Japanese speed skater *, Japanese actress *, Japanese gravure idol and television personality *, Japanese long-distance runner *, Japanese singer-songwriter *, Imperial Japanese Army flight captain *, Japanese automotive engineer *, Japanese footballer *, Japanese singer and actress *, Japanese general *, Japanese boxer Fictional characters * , a character from the manga series '' Great Teacher Onizuka' ...
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Osaka University
, abbreviated as , is a public research university located in Osaka Prefecture, Japan. It is one of Japan's former Imperial Universities and a Designated National University listed as a "Top Type" university in the Top Global University Project. The university is often ranked among the top three public universities in Japan, along with the University of Tokyo and Kyoto University. It is ranked third overall among Japanese universities and 75th worldwide in the 2022 QS World University Rankings. Osaka University was one of the earliest modern universities in Japan at its founding in 1931. The history of the institution includes much older predecessors in Osaka such as the Kaitokudō founded in 1724 and the Tekijuku founded in 1838. In 2007, it merged with Osaka University of Foreign Studies and became the largest national university in Japan. Osaka University is one of the most productive research institutions in Japan. Numerous prominent scholars and scientists have attended or w ...
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Takeda Medical Science Prize
is a Japanese family name.1990 Census Name Files
Throughout the course of the Sengoku period (16th century) of Japan, the famed Takeda clan of Kai Province had many descendant branch families. * Takeda clan (Aki) is a family in the Aki Province *

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Nishinomiya, Hyōgo
270px, Nishinomiya City Hall 270px, Aerial view of Nishinomiya city center 270px, Hirota Shrine is a city located in Hyōgo Prefecture, Japan. , the city had an estimated population of 484,368 in 218948 households and a population density of 4800 persons per km². The total area of the city is . Nishinomiya is an important commercial and shipping city in the Kansai region with the third largest population in Hyōgo Prefecture. Nishinomiya is best known as the home of Kōshien Stadium, where the Hanshin Tigers baseball team plays home games and where Japan's annual high school baseball championship is held. Geography Nishinomiya is located in southeast Hyōgo Prefecture between the cities of Kobe and Osaka. It is bordered by Osaka Bay to the south, the cities of Amagasaki, Itami and Takarazuka along the Mukogawa and Nigawa rivers to the east and by a part of the Rokkō Mountains and Kobe to the north. The city can be divided into two areas: a mountainous area in the north ...
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Hyōgo Prefecture
is a prefecture of Japan located in the Kansai region of Honshu. Hyōgo Prefecture has a population of 5,469,762 () and has a geographic area of . Hyōgo Prefecture borders Kyoto Prefecture to the east, Osaka Prefecture to the southeast, and Okayama Prefecture and Tottori Prefecture to the west. Kōbe is the capital and largest city of Hyōgo Prefecture, and the seventh-largest city in Japan, with other major cities including Himeji, Nishinomiya, and Amagasaki. Hyōgo Prefecture's mainland stretches from the Sea of Japan to the Seto Inland Sea, where Awaji Island and a small archipelago of islands belonging to the prefecture are located. Hyōgo Prefecture is a major economic center, transportation hub, and tourist destination in western Japan, with 20% of the prefecture's land area designated as Natural Parks. Hyōgo Prefecture forms part of the Keihanshin metropolitan area, the second-most-populated urban region in Japan after the Greater Tokyo area and one of the w ...
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Tarui's Disease
Phosphofructokinase deficiency is a rare muscular metabolic disorder, with an autosomal recessive inheritance pattern. It may affect humans as well as other mammals (especially dogs). It was named after the Japanese physician Seiichiro Tarui (b. 1927), who first observed the condition in 1965. Presentation In humans Human PFK deficiency is categorized into four types: classic, late-onset, infantile and hemolytic. These types are differentiated by age at which symptoms are observed and which symptoms present. Classic form Classic phosphofructokinase deficiency is the most common type of this disorder. This type presents with exercise-induced muscle cramps and weakness (sometimes rhabdomyolysis), myoglobinuria, as well as with haemolytic anaemia causing dark urine a few hours later. Hyperuricemia is common, due to the kidneys' inability to process uric acid following damage resulting from processing myoglobin. Nausea and vomiting following strenuous exercise is another common ind ...
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Glycogen
Glycogen is a multibranched polysaccharide of glucose that serves as a form of energy storage in animals, fungi, and bacteria. The polysaccharide structure represents the main storage form of glucose in the body. Glycogen functions as one of two forms of energy reserves, glycogen being for short-term and the other form being triglyceride stores in adipose tissue (i.e., body fat) for long-term storage. In humans, glycogen is made and stored primarily in the cells of the liver and skeletal muscle. In the liver, glycogen can make up 5–6% of the organ's fresh weight, and the liver of an adult, weighing 1.5 kg, can store roughly 100–120 grams of glycogen. In skeletal muscle, glycogen is found in a low concentration (1–2% of the muscle mass) and the skeletal muscle of an adult weighing 70 kg stores roughly 400 grams of glycogen. The amount of glycogen stored in the body—particularly within the muscles and liver—mostly depends on physical training, bas ...
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Metabolism
Metabolism (, from el, μεταβολή ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run cellular processes; the conversion of food to building blocks for proteins, lipids, nucleic acids, and some carbohydrates; and the elimination of metabolic wastes. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. The word metabolism can also refer to the sum of all chemical reactions that occur in living organisms, including digestion and the transportation of substances into and between different cells, in which case the above described set of reactions within the cells is called intermediary (or intermediate) metabolism. Metabolic reactions may be categorized as ''catabolic'' – the ''breaking down'' of compounds (for example, of glucose to pyruvate by ce ...
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1927 Births
Nineteen or 19 may refer to: * 19 (number), the natural number following 18 and preceding 20 * one of the years 19 BC, AD 19, 1919, 2019 Films * ''19'' (film), a 2001 Japanese film * ''Nineteen'' (film), a 1987 science fiction film Music * 19 (band), a Japanese pop music duo Albums * ''19'' (Adele album), 2008 * ''19'', a 2003 album by Alsou * ''19'', a 2006 album by Evan Yo * ''19'', a 2018 album by MHD * ''19'', one half of the double album ''63/19'' by Kool A.D. * ''Number Nineteen'', a 1971 album by American jazz pianist Mal Waldron * ''XIX'' (EP), a 2019 EP by 1the9 Songs * "19" (song), a 1985 song by British musician Paul Hardcastle. * "Nineteen", a song by Bad4Good from the 1992 album '' Refugee'' * "Nineteen", a song by Karma to Burn from the 2001 album ''Almost Heathen''. * "Nineteen" (song), a 2007 song by American singer Billy Ray Cyrus. * "Nineteen", a song by Tegan and Sara from the 2007 album '' The Con''. * "XIX" (song), a 2014 song by Slipk ...
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