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Papworth Hospital
Royal Papworth Hospital is a specialist heart and lung hospital, located on the Cambridge Biomedical Campus in Cambridgeshire, England. The Hospital is run by Royal Papworth Hospital NHS Foundation Trust. The hospital is a world-leading cardiothoracic transplant centre and the biggest in the UK, having carried out more heart and lung transplants in 2019/20 than any other hospital. It is also home to the UK's biggest sleep centre, and is one of five hospitals commissioned by NHS England to provide Extra Corporeal Membrane Oxygenation (ECMO) to adults with severe respiratory failure. History Papworth Hospital was founded at Papworth Everard (to the west of Cambridge) in 1918 as a sanatorium for the treatment of tuberculosis among discharged soldiers who had served in the First World War, following a campaign led by Elsbeth Dimsdale, and was initially known as the “Cambridgeshire Tuberculosis Colony”. The institution was initially under the direction of Dr (later Sir) Pendri ...
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Cambridge Biomedical Campus
The Cambridge Biomedical Campus is the largest centre of medical research and health science in Europe. The site is located at the southern end of Hills Road in Cambridge, England. Over 20,000 people work at the site, which is home to Cambridge University Hospitals NHS Foundation Trust, Royal Papworth Hospital NHS Foundation Trust, AstraZeneca's headquarters, Abcam, the Wellcome Trust, Cancer Research UK, the University of Cambridge's medical school, and the United Kingdom's governmental Medical Research Council, which has National Institute for Health and Care Research-designated biomedical research centre status. Cambridge Biomedical Campus is an accredited UK academic health and science centre. Constituent institutions The Cambridge Biomedical Campus is home to the following institutions. Cambridge University Hospitals NHS Foundation Trust Addenbrooke's hospital Addenbrooke's Hospital is a large teaching hospital, and the central focus of the campus. Rosie maternity ho ...
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Roy Yorke Calne
Sir Roy Yorke Calne, FRCP, FRCS, FRS (born 30 December 1930) is a British surgeon and pioneer in organ transplantation. Career His most notable achievements are the world's first liver, heart, and lung transplant together with John Wallwork in 1987; the first successful combined stomach, intestine, pancreas, liver, and kidney cluster transplant in 1994, the first liver transplantation operation in Europe in 1968, and the first intestinal transplant in the UK in 1992. Calne is a fellow of the Royal Society and was Professor of Surgery at Cambridge University between 1965 and 1998 where he initiated the kidney transplant program. He was Harkness Fellow at Harvard Medical School from 1960 to 1961. Much of his subsequent work has been concerned with the improvement of immunosuppression techniques aimed at prolonging the life of liver transplant recipients. He is currently the Yoah Ghim Professor of Surgery at the National University of Singapore. Awards and honours He was elec ...
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Narcolepsy
Narcolepsy is a long-term neurological disorder that involves a decreased ability to regulate sleep–wake cycles. Symptoms often include periods of excessive daytime sleepiness and brief involuntary sleep episodes. About 70% of those affected also experience episodes of sudden loss of muscle strength, known as cataplexy. Narcolepsy paired with cataplexy is evidenced to be an autoimmune disorder. These experiences of cataplexy can be brought on by strong emotions. Less commonly, there may be vivid hallucinations or an inability to move (sleep paralysis) while falling asleep or waking up. People with narcolepsy tend to sleep about the same number of hours per day as people without, but the quality of sleep tends to be lessened. Narcolepsy is a clinical syndrome of hypothalamic disorder, however, the exact cause of narcolepsy is unknown, with potentially several causes. In up to 10% of cases, there is a family history of the disorder. Often, those affected have low levels of ...
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Obstructive Sleep Apnoea
Obstructive sleep apnea (OSA) is the most common sleep-related breathing disorder and is characterized by recurrent episodes of complete or partial obstruction of the upper airway leading to reduced or absent breathing during sleep. These episodes are termed " apneas" with complete or near-complete cessation of breathing, or "hypopneas" when the reduction in breathing is partial. In either case, a fall in blood oxygen saturation, a disruption in sleep, or both may result. A high frequency of apneas or hypopneas during sleep may interfere with restorative sleep, whichin combination with disturbances in blood oxygenationis thought to contribute to negative consequences to health and quality of life. The terms obstructive sleep apnea syndrome (OSAS) or obstructive sleep apnea–hypopnea syndrome (OSAHS) may be used to refer to OSA when it is associated with symptoms during the daytime (e.g. excessive daytime sleepiness, decreased cognitive function). Most individuals with OSA are ...
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Sleep Disorders
A sleep disorder, or somnipathy, is a medical disorder of an individual's sleep patterns. Some sleep disorders are severe enough to interfere with normal physical, mental, social and emotional functioning. Polysomnography and actigraphy are tests commonly ordered for diagnosing sleep disorders. Sleep disorders are broadly classified into dyssomnias, parasomnias, circadian rhythm sleep disorders involving the timing of sleep, and other disorders including ones caused by medical or psychological conditions. When a person struggles to fall asleep and/or stay asleep with no obvious cause, it is referred to as insomnia, the most common sleep disorder. Others include sleep apnea, narcolepsy and hypersomnia (excessive sleepiness at inappropriate times), sleeping sickness (disruption of sleep cycle due to infection), sleepwalking, and night terrors. Sleep disruptions can be caused by various issues, including teeth grinding ( bruxism) and night terrors. Management of sleep disturbances ...
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Elizabeth II
Elizabeth II (Elizabeth Alexandra Mary; 21 April 1926 – 8 September 2022) was Queen of the United Kingdom and other Commonwealth realms from 6 February 1952 until her death in 2022. She was queen regnant of 32 sovereign states during her lifetime, and was head of state of 15 realms at the time of her death. Her reign of 70 years and 214 days was the longest of any British monarch and the longest verified reign of any female monarch in history. Elizabeth was born in Mayfair, London, as the first child of the Duke and Duchess of York (later King George VI and Queen Elizabeth The Queen Mother). Her father acceded to the throne in 1936 upon the abdication of his brother Edward VIII, making the ten-year-old Princess Elizabeth the heir presumptive. She was educated privately at home and began to undertake public duties during the Second World War, serving in the Auxiliary Territorial Service. In November 1947, she married Philip Mountbatten, a former prince ...
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Heart Transplantation
A heart transplant, or a cardiac transplant, is a surgical transplant procedure performed on patients with end-stage heart failure or severe coronary artery disease when other medical or surgical treatments have failed. , the most common procedure is to take a functioning heart, with or without both lungs, from a recently deceased organ donor (brain death is the standard) and implant it into the patient. The patient's own heart is either removed and replaced with the donor heart ( orthotopic procedure) or, much less commonly, the recipient's diseased heart is left in place to support the donor heart (heterotopic, or "piggyback", transplant procedure). Approximately 3,500 heart transplants are performed each year worldwide, more than half of which are in the US. Post-operative survival periods average 15 years. Heart transplantation is not considered to be a cure for heart disease; rather it is a life-saving treatment intended to improve the quality and duration of life for a reci ...
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Skanska
Skanska AB () is a multinational construction and development company based in Sweden. Skanska is the fifth-largest construction company in the world according to ''Construction Global'' magazine. Notable Skanska projects include renovation of the United Nations Headquarters, the World Trade Center Transportation Hub project, Moynihan Train Hall, 30 St Mary Axe, MetLife Stadium, Mater Dei Hospital, among others. History Aktiebolaget Skånska Cementgjuteriet (Scanian Cement Casting Ltd) was established in Malmö, Sweden, in 1887 by Rudolf Fredrik Berg and started by manufacturing concrete products.Skanska: History
It quickly diversified into a construction company and within ten years the company received its first international order. The company played an important role in building Sweden's infrastructure i ...
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Private Finance Initiative
The private finance initiative (PFI) was a United Kingdom government procurement policy aimed at creating "public–private partnerships" (PPPs) where private firms are contracted to complete and manage public projects. Initially launched in 1992 by Prime Minister John Major, and expanded considerably by the Blair government, PFI is part of the wider programme of privatisation and financialisation, and presented as a means for increasing accountability and efficiency for public spending. PFI was controversial in the UK. In 2003, the National Audit Office felt that it provided good value for money overall; according to critics, PFI has been used simply to place a great amount of debt "off-balance-sheet". In 2011, the parliamentary Treasury Select Committee recommended: In October 2018, the then-chancellor Philip Hammond announced that the UK government would no longer use PFI; however, PFI projects will continue to operate for some time to come. In 2021, Robert Naylor warned ...
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The Guardian
''The Guardian'' is a British daily newspaper. It was founded in 1821 as ''The Manchester Guardian'', and changed its name in 1959. Along with its sister papers ''The Observer'' and ''The Guardian Weekly'', ''The Guardian'' is part of the Guardian Media Group, owned by the Scott Trust. The trust was created in 1936 to "secure the financial and editorial independence of ''The Guardian'' in perpetuity and to safeguard the journalistic freedom and liberal values of ''The Guardian'' free from commercial or political interference". The trust was converted into a limited company in 2008, with a constitution written so as to maintain for ''The Guardian'' the same protections as were built into the structure of the Scott Trust by its creators. Profits are reinvested in journalism rather than distributed to owners or shareholders. It is considered a newspaper of record in the UK. The editor-in-chief Katharine Viner succeeded Alan Rusbridger in 2015. Since 2018, the paper's main news ...
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Peterborough City Hospital
Peterborough City Hospital is an acute teaching hospital on the Edith Cavell Healthcare Campus serving the city of Peterborough, north Cambridgeshire, areas of east Northamptonshire and Rutland. It is managed by North West Anglia NHS Foundation Trust. History The hospital was procured under a Private Finance Initiative contract in 2007 to replace Peterborough District Hospital and the Edith Cavell Hospital. It was designed by Nightingale Associates and built on the site of the Edith Cavell Hospital by Multiplex at a cost of £340 million and opened to patients in November 2010. The official opening was carried out by the Duke and Duchess of Cambridge in November 2012. In same month, the National Audit Office reported that the Trust board's poor financial management and procurement of the scheme, which had been unaffordable, had left the Trust in a critical financial position. Facilities The 612 bed hospital has a Cancer Centre, Cardiology Centre, a Women's and Children's Uni ...
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BBC News
BBC News is an operational business division of the British Broadcasting Corporation (BBC) responsible for the gathering and broadcasting of news and current affairs in the UK and around the world. The department is the world's largest broadcast news organisation and generates about 120 hours of radio and television output each day, as well as online news coverage. The service maintains 50 foreign news bureaus with more than 250 correspondents around the world. Deborah Turness has been the CEO of news and current affairs since September 2022. In 2019, it was reported in an Ofcom report that the BBC spent £136m on news during the period April 2018 to March 2019. BBC News' domestic, global and online news divisions are housed within the largest live newsroom in Europe, in Broadcasting House in central London. Parliamentary coverage is produced and broadcast from studios in London. Through BBC English Regions, the BBC also has regional centres across England and national news c ...
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