Pål Nyrén
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Pål Nyrén
Pål Nyrén (born 1955) is a biochemistry professor at the Royal Institute of Technology (KTH), Stockholm. He is most famous for developing the pyrosequencing method for DNA sequencing. Career *1999 Professor in Biochemistry, KTH, Stockholm *1997 Founder of the company Biotage AB (former Pyrosequencing AB) *1988 Associate professor (Docent) Biochemistry, University of Stockholm *1985-86 Postdoc at LMB, MRC, Cambridge, G.B. with prof John Walker *1985 PhD (Tekn. Doktor) Biochemistry, University of Stockholm (Thesis title: "The proton pumping pyrophosphatase from ''Rhodospirillum rubrum''") *1981 MSc (Civ. ing.) Chemical Engineering, KTH, Stockholm Recognition *2013 winner of the European Inventor Award in the SMEs categoryInvention


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Biochemistry
Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and metabolism. Over the last decades of the 20th century, biochemistry has become successful at explaining living processes through these three disciplines. Almost all areas of the life sciences are being uncovered and developed through biochemical methodology and research. Voet (2005), p. 3. Biochemistry focuses on understanding the chemical basis which allows biological molecules to give rise to the processes that occur within living cells and between cells,Karp (2009), p. 2. in turn relating greatly to the understanding of tissues and organs, as well as organism structure and function.Miller (2012). p. 62. Biochemistry is closely related to molecular biology, which is the study of the molecular mechanisms of biological phenomena.As ...
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Royal Institute Of Technology
The KTH Royal Institute of Technology ( sv, Kungliga Tekniska högskolan, lit=Royal Institute of Technology), abbreviated KTH, is a public research university in Stockholm, Sweden. KTH conducts research and education in engineering and technology and is Sweden's largest technical university. Currently, KTH consists of five schools with four campuses in and around Stockholm. KTH was established in 1827 as the ''Teknologiska institutet (Institute of Technology)'' and had its roots in the ''Mekaniska skolan (School of Mechanics)'' that was established in 1798 in Stockholm. But the origin of KTH dates back to the predecessor of the ''Mekaniska skolan'', the ''Laboratorium mechanicum'', which was established in 1697 by the Swedish scientist and innovator Christopher Polhem. The Laboratorium mechanicum combined education technology, a laboratory, and an exhibition space for innovations. In 1877 KTH received its current name, Kungliga Tekniska högskolan (KTH Royal Institute of Technol ...
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Stockholm
Stockholm () is the Capital city, capital and List of urban areas in Sweden by population, largest city of Sweden as well as the List of urban areas in the Nordic countries, largest urban area in Scandinavia. Approximately 980,000 people live in the Stockholm Municipality, municipality, with 1.6 million in the Stockholm urban area, urban area, and 2.4 million in the Metropolitan Stockholm, metropolitan area. The city stretches across fourteen islands where Mälaren, Lake Mälaren flows into the Baltic Sea. Outside the city to the east, and along the coast, is the island chain of the Stockholm archipelago. The area has been settled since the Stone Age, in the 6th millennium BC, and was founded as a city in 1252 by Swedish statesman Birger Jarl. It is also the county seat of Stockholm County. For several hundred years, Stockholm was the capital of Finland as well (), which then was a part of Sweden. The population of the municipality of Stockholm is expected to reach o ...
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Pyrosequencing
Pyrosequencing is a method of DNA sequencing (determining the order of nucleotides in DNA) based on the "sequencing by synthesis" principle, in which the sequencing is performed by detecting the nucleotide incorporated by a DNA polymerase. Pyrosequencing relies on light detection based on a chain reaction when pyrophosphate is released. Hence, the name pyrosequencing. The principle of pyrosequencing was first described in 1993 by, Bertil Pettersson, Mathias Uhlen and Pål Nyren by combining the solid phase sequencing method using streptavidin coated magnetic beads with recombinant DNA polymerase lacking 3´to 5´exonuclease activity (proof-reading) and luminescence detection using the firefly luciferase enzyme. A mixture of three enzymes (DNA polymerase, ATP sulfurylase and firefly luciferase) and a nucleotide (dNTP) are added to single stranded DNA to be sequenced and the incorporation of nucleotide is followed by measuring the light emitted. The intensity of the light determi ...
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Pyrosequencing
Pyrosequencing is a method of DNA sequencing (determining the order of nucleotides in DNA) based on the "sequencing by synthesis" principle, in which the sequencing is performed by detecting the nucleotide incorporated by a DNA polymerase. Pyrosequencing relies on light detection based on a chain reaction when pyrophosphate is released. Hence, the name pyrosequencing. The principle of pyrosequencing was first described in 1993 by, Bertil Pettersson, Mathias Uhlen and Pål Nyren by combining the solid phase sequencing method using streptavidin coated magnetic beads with recombinant DNA polymerase lacking 3´to 5´exonuclease activity (proof-reading) and luminescence detection using the firefly luciferase enzyme. A mixture of three enzymes (DNA polymerase, ATP sulfurylase and firefly luciferase) and a nucleotide (dNTP) are added to single stranded DNA to be sequenced and the incorporation of nucleotide is followed by measuring the light emitted. The intensity of the light determi ...
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Professor
Professor (commonly abbreviated as Prof.) is an Academy, academic rank at university, universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a "person who professes". Professors are usually experts in their field and teachers of the highest rank. In most systems of List of academic ranks, academic ranks, "professor" as an unqualified title refers only to the most senior academic position, sometimes informally known as "full professor". In some countries and institutions, the word "professor" is also used in titles of lower ranks such as associate professor and assistant professor; this is particularly the case in the United States, where the unqualified word is also used colloquially to refer to associate and assistant professors as well. This usage would be considered incorrect among other academic communities. However, the otherwise unqualified title "Professor" designated with a capital let ...
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University Of Stockholm
Stockholm University ( sv, Stockholms universitet) is a public research university in Stockholm, Sweden, founded as a college in 1878, with university status since 1960. With over 33,000 students at four different faculties: law, humanities, social sciences, and natural sciences, it is one of the largest universities in Scandinavia. The institution is regarded as one of the top 100 universities in the world by the Academic Ranking of World Universities (ARWU).http://www.ulinks.com/topuniversities.htm top 200 Stockholm University was granted university status in 1960, making it the fourth oldest Swedish university. As with other public universities in Sweden, Stockholm University's mission includes teaching and research anchored in society at large. History The initiative for the formation of Stockholm University was taken by the Stockholm City Council. The process was completed after a decision in December 1865 regarding the establishment of a fund and a committee to "establish ...
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European Inventor Award
The European Inventor Award(formerly European Inventor of the Year Award, renamed in 2010), are presented annually by the European Patent Office, sometimes supported by the respective Presidency of the Council of the European Union and by the European Commission, to inventors who have made a significant contribution to innovation, economy and society in Europe. Inventions from all technological fields are considered for this award. The winners in each category are presented with an award shaped like a sail. There is no cash prize associated with the award. Award categories The European Inventor Award is presented in the following five categories: *Industry *Small and medium-sized enterprises (SMEs) *Research *Non-European countries *Lifetime achievement Since 2013, the public is invited to vote to select the winner of a ''Popular Prize'' from among the finalists. Nomination and selection Each year the European Patent Office calls on its patent examiners, on examiners at the pate ...
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European Patent Office
The European Patent Office (EPO) is one of the two organs of the European Patent Organisation (EPOrg), the other being the Administrative Council. The EPO acts as executive body for the organisationGower's Report on Intellectual Property
, para 1.34
while the Administrative Council acts as its supervisory body as well as, to a limited extent, its legislative body. The actual legislative power to revise the lies with the Contracting States themselves when meeting at a Conference of the Contracting States. Within the European Patent Office,
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1955 Births
Events January * January 3 – José Ramón Guizado becomes president of Panama. * January 17 – , the first nuclear-powered submarine, puts to sea for the first time, from Groton, Connecticut. * January 18– 20 – Battle of Yijiangshan Islands: The Chinese Communist People's Liberation Army seizes the islands from the Republic of China (Taiwan). * January 22 – In the United States, The Pentagon announces a plan to develop intercontinental ballistic missiles (ICBMs), armed with nuclear weapons. * January 23 – The Sutton Coldfield rail crash kills 17, near Birmingham, England. * January 25 – The Presidium of the Supreme Soviet of the Soviet Union announces the end of the war between the USSR and Germany, which began during World War II in 1941. * January 28 – The United States Congress authorizes President Dwight D. Eisenhower to use force to protect Formosa from the People's Republic of China. February * February 10 – The United States Sev ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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Swedish Chemists
Swedish or ' may refer to: Anything from or related to Sweden, a country in Northern Europe. Or, specifically: * Swedish language, a North Germanic language spoken primarily in Sweden and Finland ** Swedish alphabet, the official alphabet used by the Swedish language * Swedish people or Swedes, persons with a Swedish ancestral or ethnic identity ** A national or citizen of Sweden, see demographics of Sweden ** Culture of Sweden * Swedish cuisine See also * * Swedish Church (other) * Swedish Institute (other) * Swedish invasion (other) * Swedish Open (other) Swedish Open is a tennis tournament. Swedish Open may also refer to: *Swedish Open (badminton) * Swedish Open (table tennis) *Swedish Open (squash) *Swedish Open (darts) The Swedish Open is a darts tournament established in 1969, held in Malmà ... {{disambig Language and nationality disambiguation pages ...
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