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Plaque Hypotheses
Plaque hypotheses are theories to explain the role of dental plaque, plaque bacteria in dental caries and in periodontitis. They rely heavily on the Koch's postulates, postulates of Robert Koch, Koch (formulated in 1884) and on the work of Louis Pasteur (1822–1895). Changing perceptions have altered dental treatment, treatment models. The hypotheses have sought to establish both in caries and in periodontitis a relation between pathogen virulence, environmental considerations, plaque biofilm structure and the host response. Specific plaque hypothesis The specific plaque hypothesis was the favoured opinion at the birth of microbiology in the late nineteenth century. It posited that there were some specific pathogenic bacteria among the biome which were solely responsible for disease, and in the absence of which the oral environment would be healthy. In his “Nonspecific plaque hypothesis”, the hypothesis states that the severity of the disease depends upon the amount of plaque ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dental Plaque
Dental plaque is a biofilm of microorganisms (mostly bacteria, but also fungi) that grows on surfaces within the mouth. It is a sticky colorless deposit at first, but when it forms tartar, it is often brown or pale yellow. It is commonly found between the teeth, on the front of teeth, behind teeth, on chewing surfaces, along the gumline (supragingival), or below the gumline cervical margins (subgingival). Dental plaque is also known as microbial plaque, oral biofilm, dental biofilm, dental plaque biofilm or bacterial plaque biofilm. Bacterial plaque is one of the major causes for dental decay and gum disease. Progression and build-up of dental plaque can give rise to tooth decay – the localised destruction of the tissues of the tooth by acid produced from the bacterial degradation of fermentable sugar – and periodontal problems such as gingivitis and periodontitis; hence it is important to disrupt the mass of bacteria and remove it. Plaque control and removal can be achieved w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dental Caries
Tooth decay, also known as cavities or caries, is the breakdown of teeth due to acids produced by bacteria. The cavities may be a number of different colors from yellow to black. Symptoms may include pain and difficulty with eating. Complications may include inflammation of the tissue around the tooth, tooth loss and infection or abscess formation. The cause of cavities is acid from bacteria dissolving the hard tissues of the teeth ( enamel, dentin and cementum). The acid is produced by the bacteria when they break down food debris or sugar on the tooth surface. Simple sugars in food are these bacteria's primary energy source and thus a diet high in simple sugar is a risk factor. If mineral breakdown is greater than build up from sources such as saliva, caries results. Risk factors include conditions that result in less saliva such as: diabetes mellitus, Sjögren syndrome and some medications. Medications that decrease saliva production include antihistamines and antide ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Periodontitis
Periodontal disease, also known as gum disease, is a set of inflammatory conditions affecting the tissues surrounding the teeth. In its early stage, called gingivitis, the gums become swollen and red and may bleed. It is considered the main cause of tooth loss for adults worldwide.V. Baelum and R. Lopez, “Periodontal epidemiology: towards social science or molecular biology?,”Community Dentistry and Oral Epidemiology, vol. 32, no. 4, pp. 239–249, 2004.Nicchio I, Cirelli T, Nepomuceno R, et al. Polymorphisms in Genes of Lipid Metabolism Are Associated with Type 2 Diabetes Mellitus and Periodontitis, as Comorbidities, and with the Subjects' Periodontal, Glycemic, and Lipid Profiles Journal of Diabetes Research. 2021 Jan;2021. PMCID: PMC8601849. In its more serious form, called periodontitis, the gums can pull away from the tooth, bone can be lost, and the teeth may loosen or fall out. Bad breath may also occur. Periodontal disease is generally due to bacteria in the mouth ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Koch's Postulates
Koch's postulates ( )"Koch" ''''. are four criteria designed to establish a between a and a . The postulates were formulated by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robert Koch
Heinrich Hermann Robert Koch ( , ; 11 December 1843 – 27 May 1910) was a German physician and microbiologist. As the discoverer of the specific causative agents of deadly infectious diseases including tuberculosis, cholera (though the Vibrio cholerae, bacterium itself was discovered by Filippo Pacini in 1854), and anthrax, he is regarded as one of the main founders of modern bacteriology. As such he is popularly nicknamed the father of microbiology (with Louis Pasteur), and as the father of medical bacteriology. His discovery of the anthrax bacterium (''Bacillus anthracis'') in 1876 is considered as the birth of modern bacteriology. His discoveries directly provided proofs for the germ theory of diseases, and the scientific basis of public health. While working as a private physician, Koch developed many innovative techniques in microbiology. He was the first to use the oil immersion lens, Condenser (optics), condenser, and microphotography in microscopy. His invention of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Louis Pasteur
Louis Pasteur (, ; 27 December 1822 – 28 September 1895) was a French chemist and microbiologist renowned for his discoveries of the principles of vaccination, microbial fermentation and pasteurization, the latter of which was named after him. His research in chemistry led to remarkable breakthroughs in the understanding of the causes and preventions of diseases, which laid down the foundations of hygiene, public health and much of modern medicine. His works are credited to saving millions of lives through the developments of vaccines for rabies and anthrax. He is regarded as one of the founders of modern bacteriology and has been honored as the "father of bacteriology" and the "father of microbiology" (together with Robert Koch; the latter epithet also attributed to Antonie van Leeuwenhoek). Pasteur was responsible for disproving the doctrine of spontaneous generation. Under the auspices of the French Academy of Sciences, his experiment demonstrated that in sterilized ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dental Treatment
Dental surgery is any of a number of medical procedures that involve artificially modifying dentition; in other words, surgery of the teeth, gums and jaw bones. Types Some of the more common are: * Endodontic (surgery involving the pulp or root of the tooth) ** Root canal treatment *** Pulpotomy — the opening of the pulp chamber of the tooth to allow an infection to drain; usually a precursor to a root canal *** Pulpectomy — the removal of the pulp from the pulp chamber to temporarily relieve pain; usually a precursor to a root canal ** Apicoectomy — a root-end resection. Occasionally a root canal alone is enough to relieve pain and the end of the tooth, called the apex, is removed by entering through the gingiva and surgically extracting the diseased material. * Prosthodontics (dental prosthetics) ** Crown (caps) — artificial covering of a tooth made from a variety of biocompatible materials, including CMC/PMC (ceramic/porcelain metal composite), gold ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pathogen
In biology, a pathogen ( el, πάθος, "suffering", "passion" and , "producer of") in the oldest and broadest sense, is any organism or agent that can produce disease. A pathogen may also be referred to as an infectious agent, or simply a germ. The term ''pathogen'' came into use in the 1880s. Typically, the term ''pathogen'' is used to describe an ''infectious'' microorganism or agent, such as a virus, bacterium, protozoan, prion, viroid, or fungus. Small animals, such as helminths and insects, can also cause or transmit disease. However, these animals are usually referred to as parasites rather than pathogens. The scientific study of microscopic organisms, including microscopic pathogenic organisms, is called microbiology, while parasitology refers to the scientific study of parasites and the organisms that host them. There are several pathways through which pathogens can invade a host. The principal pathways have different episodic time frames, but soil has the longest ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Virulence
Virulence is a pathogen's or microorganism's ability to cause damage to a host. In most, especially in animal systems, virulence refers to the degree of damage caused by a microbe to its host. The pathogenicity of an organism—its ability to cause disease—is determined by its virulence factors. In the specific context of gene for gene systems, often in plants, virulence refers to a pathogen's ability to infect a resistant host. The noun ''virulence'' derives from the adjective ''virulent'', meaning disease severity. The word ''virulent'' derives from the Latin word ''virulentus'', meaning "a poisoned wound" or "full of poison." From an ecological standpoint, virulence is the loss of fitness induced by a parasite upon its host. Virulence can be understood in terms of proximate causes—those specific traits of the pathogen that help make the host ill—and ultimate causes—the evolutionary pressures that lead to virulent traits occurring in a pathogen strain. Virulent ba ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Streptococcus Mutans
''Streptococcus mutans'' is a facultatively anaerobic, gram-positive coccus (round bacterium) commonly found in the human oral cavity and is a significant contributor to tooth decay. It is part of the " streptococci" (plural, non-italic lowercase), an informal general name for all species in the genus ''Streptococcus''. The microbe was first described by James Kilian Clarke in 1924. This bacterium, along with the closely related species ''Streptococcus sobrinus'', can cohabit the mouth: Both contribute to oral disease, and the expense of differentiating them in laboratory testing is often not clinically necessary. Therefore, for clinical purposes they are often considered together as a group, called the mutans streptococci (plural, non-italic due to its being an informal group name). This grouping of similar bacteria with similar tropism can also be seen in the viridans streptococci, another group of ''Streptococcus'' species. Ecology ''S. mutans'' is naturally present in the hu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lactobacilli
The ''Lactobacillaceae'' are a family of lactic acid bacteria. It is the only family in the lactic acid bacteria which includes homofermentative and heterofermentative organisms; in the ''Lactobacillaceae,'' the pathway used for hexose fermentation is a genus-specific trait. ''Lactobacillaceae'' include the homofermentative lactobacilli ''Lactobacillus'', ''Holzapfelia'', ''Amylolactobacillus'', ''Bombilactobacillus'', ''Companilactobacillus'', ''Lapidilactobacillus'', ''Agrilactobacillus'', ''Schleiferilactobacillus'', ''Loigolactobacillus'', ''Lacticaseibacillus'', ''Latilactobacillus'', ''Dellaglioa'', ''Liquorilactobacillus'', ''Ligilactobacillus'', and ''Lactiplantibacillus''; the heterofermentative lactobacilli ''Furfurilactobacillus'', ''Paucilactobacillus'', ''Limosilactobacillus'', ''Fructilactobacillus'', ''Acetilactobacillus'', ''Apilactobacillus'', ''Levilactobacillus'', ''Secundilactobacillus'', and ''Lentilactobacillus,'' which were previously classified in the genus ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ecological Plaque Hypothesis And The Aetiology Of Dental Caries
Ecology () is the study of the relationships between living organisms, including humans, and their physical environment. Ecology considers organisms at the individual, population, community, ecosystem, and biosphere level. Ecology overlaps with the closely related sciences of biogeography, evolutionary biology, genetics, ethology, and natural history. Ecology is a branch of biology, and it is not synonymous with environmentalism. Among other things, ecology is the study of: * The abundance, biomass, and distribution of organisms in the context of the environment * Life processes, antifragility, interactions, and adaptations * The movement of materials and energy through living communities * The successional development of ecosystems * Cooperation, competition, and predation within and between species * Patterns of biodiversity and its effect on ecosystem processes Ecology has practical applications in conservation biology, wetland management, natural resourc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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