Peter M. Howley
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Peter M. Howley
Peter Maxwell Howley (born October 9, 1946) is an American pathologist, virologist, and professor at Harvard Medical School. He has been president of the American Society for Virology and the American Society for Investigative Pathology and a co-editor of the '' Annual Review of Pathology: Mechanisms of Disease''. Biography Howley was born in New Brunswick, New Jersey. He graduated in 1968 from Princeton University with an A.B. in chemistry and in 1970 from Rutgers University with an M.M.S. (Master of Medical Science) degree. In 1972 he graduated with an M.D. from Harvard Medical School. From 1972 to 1973 he worked as an intern in pathology at Massachusetts General Hospital. He was a research associate from 1973 to 1975 at the National Institute of Allergy and Infectious Diseases (NIAID) in Bethesda, Maryland. In 1977 he was granted board certification in anatomic pathology. At the NCI's Laboratory of Pathology, Howley was from 1975 to 1976 a resident, from 1976 to 1977 a juni ...
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Harvard Medical School
Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consistently ranked first for research among medical schools by '' U.S. News & World Report''. Unlike most other leading medical schools, HMS does not operate in conjunction with a single hospital but is directly affiliated with several teaching hospitals in the Boston area. Affiliated teaching hospitals and research institutes include Dana–Farber Cancer Institute, Massachusetts General Hospital, Brigham and Women's Hospital, Beth Israel Deaconess Medical Center, Boston Children's Hospital, McLean Hospital, Cambridge Health Alliance, The Baker Center for Children and Families, and Spaulding Rehabilitation Hospital. History Harvard Medical School was founded on September 19, 1782, after President Joseph Willard presented a report with ...
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Oncogene
An oncogene is a gene that has the potential to cause cancer. In tumor cells, these genes are often mutated, or expressed at high levels.Kimball's Biology Pages.
"Oncogenes" Free full text
Most normal cells will undergo a programmed form of rapid cell death () when critical functions are altered and malfunctioning. Activated oncogenes can cause those cells designated for apoptosis to survive and proliferate instead. Most oncogenes began as proto-oncogenes: normal genes involved in cell growth and proliferation or inhibition of apoptosis. If, through mutation, normal genes promoting cellular growth are up-regulated (gain-of-function mutation), they will predisp ...
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Harald Zur Hausen
Harald zur Hausen NAS EASA APS (; born 11 March 1936) is a German virologist and professor emeritus. He has done research on cervical cancer and discovered the role of papilloma viruses in cervical cancer, for which he received the Nobel Prize in Physiology or Medicine 2008. Early life and education Zur Hausen was born in Gelsenkirchen, Germany, in a Catholic family. He completed his Abitur at Gymnasium Antonianum in Vechta, then studied medicine at the Universities of Bonn, Hamburg and Düsseldorf, and received a Doctor of Medicine degree in 1960 from the University of Düsseldorf, after which he became a medical assistant. Career Two years after qualifying as a medical doctor, he joined the Institute for Microbiology at the University of Düsseldorf as a laboratory assistant. After three and a half years there, he moved to Philadelphia to work at the Virus Laboratories of Children's Hospital of Philadelphia together with eminent virologists Werner and Gertrude Henl ...
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Paul Ehrlich And Ludwig Darmstaedter Prize
The Paul Ehrlich and Ludwig Darmstaedter Prize is an annual award bestowed by the since 1952 for investigations in medicine. It carries a prize money of 120,000 Euro. The prize awarding ceremony is traditionally held on March 14, the birthday of Nobel laureate Paul Ehrlich, in the St. Paul's Church, Frankfurt am Main. Researchers from worldwide are awarded in the following fields of medicine: Immunology, Cancer research, Haematology, Microbiology and experimental and clinical Chemotherapy. It is one of the highest endowed and internationally most distinguished awards in medicine in Germany. Some of the prize winners were later awarded the Nobel Prize. List of winners * 1952 ** , Tübingen ** , Nonnenhorn * 1953 ** Adolf Butenandt, Munich * 1954 ** Ernst Boris Chain, London * 1956 ** Gerhard Domagk, Elberfeld * 1958 ** Richard Johann Kuhn, Heidelberg * 1960 ** Felix Haurowitz, Bloomington * 1961 ** Albert Hewett Coons, Boston ** , Langen ** Örjan Ouchterlony, Gothenburg * ...
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National Academy Of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the National Academy of Medicine (NAM). As a national academy, new members of the organization are elected annually by current members, based on their distinguished and continuing achievements in original research. Election to the National Academy is one of the highest honors in the scientific field. Members of the National Academy of Sciences serve '' pro bono'' as "advisers to the nation" on science, engineering, and medicine. The group holds a congressional charter under Title 36 of the United States Code. Founded in 1863 as a result of an Act of Congress that was approved by Abraham Lincoln, the NAS is charged with "providing independent, objective advice to the nation on matters related to science and technology. ... to provide scien ...
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American Society For Clinical Investigation
The American Society for Clinical Investigation (ASCI), established in 1908, is one of the oldest and most respected medical honor societies in the United States. Organization and purpose The ASCI is an honorary society to which more than 2,800 physician-scientists from all medical specialties belong. Prospective members are proposed by standing members of the society and elected to ASCI on the basis of an outstanding record of scholarly achievement in biomedical research. The ASCI includes physician-scientists who are active clinically, in basic research, or in teaching. Many of its senior members are widely recognized leaders in academic medicine. As of 2015 the membership of ASCI has included 417 members of the National Academy of Medicine, 191 members of the National Academy of Sciences, Engineering, and Medicine, 40 Lasker Award winners, and 19 Nobel laureates. The ASCI supports the research into basic mechanisms and/or treatment of human diseases, and to the education of fut ...
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American Society For Experimental Pathology
The American Society for Investigative Pathology (ASIP) is a society of biomedical scientists who investigate mechanisms of disease. ASIP membership includes scientists in the academic, government, hospital, and pharmaceutical arenas that focus their research on the pathogenesis, classification, diagnosis and manifestations of disease. Research findings are ultimately used in the understanding, diagnosis and treatment of human diseases. The word pathology is derived from the Greek word "pathos" meaning "disease." ASIP traces its earliest beginnings to the Boston Society of Medical Sciences that was begun in 1869 by a group of faculty from Harvard Medical School. In 1901 the American Association of Pathologists and Bacteriologists (AAPB) was established. In 1976 the AAPB and the American Society for Experimental Pathology (ASEP) joined to form the American Association of Pathologists (AAP), which in 1992 became ASIP. ASIP is a member of the Federation of American Societies for Exper ...
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Melbourne, Australia
Melbourne ( ; Boonwurrung/Woiwurrung: ''Narrm'' or ''Naarm'') is the capital and most populous city of the Australian state of Victoria, and the second-most populous city in both Australia and Oceania. Its name generally refers to a metropolitan area known as Greater Melbourne, comprising an urban agglomeration of 31 local municipalities, although the name is also used specifically for the local municipality of City of Melbourne based around its central business area. The metropolis occupies much of the northern and eastern coastlines of Port Phillip Bay and spreads into the Mornington Peninsula, part of West Gippsland, as well as the hinterlands towards the Yarra Valley, the Dandenong and Macedon Ranges. It has a population over 5 million (19% of the population of Australia, as per 2021 census), mostly residing to the east side of the city centre, and its inhabitants are commonly referred to as "Melburnians". The area of Melbourne has been home to Aboriginal Victorians ...
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Proceedings Of The National Academy Of Sciences
''Proceedings of the National Academy of Sciences of the United States of America'' (often abbreviated ''PNAS'' or ''PNAS USA'') is a peer-reviewed multidisciplinary scientific journal. It is the official journal of the National Academy of Sciences, published since 1915, and publishes original research, scientific reviews, commentaries, and letters. According to ''Journal Citation Reports'', the journal has a 2021 impact factor of 12.779. ''PNAS'' is the second most cited scientific journal, with more than 1.9 million cumulative citations from 2008 to 2018. In the mass media, ''PNAS'' has been described variously as "prestigious", "sedate", "renowned" and "high impact". ''PNAS'' is a delayed open access journal, with an embargo period of six months that can be bypassed for an author fee ( hybrid open access). Since September 2017, open access articles are published under a Creative Commons license. Since January 2019, ''PNAS'' has been online-only, although print issues are a ...
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Virology
Virology is the Scientific method, scientific study of biological viruses. It is a subfield of microbiology that focuses on their detection, structure, classification and evolution, their methods of infection and exploitation of host (biology), host cell (biology), cells for reproduction, their interaction with host organism physiology and immunity, the diseases they cause, the techniques to isolate and culture them, and their use in research and therapy. The identification of the causative agent of tobacco mosaic disease (TMV) as a novel pathogen by Martinus Beijerinck (1898) is now acknowledged as being the history of virology, official beginning of the field of virology as a discipline distinct from bacteriology. He realized the source was neither a bacterial nor a fungal infection, but something completely different. Beijerinck used the word "virus" to describe the mysterious agent in his 'contagium vivum fluidum' ('contagious living fluid'). Rosalind Franklin proposed the f ...
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Fields Virology
''Fields Virology'' is an English-language virology textbook, originally it was published in two volumes and edited by Bernard N. Fields. The first edition in 1985 was called ''Virology'', but from the second edition, the book's title was changed to ''Fields Virology''. The book is widely regarded as an influential work on the subject and is cited as the ''bible of virology'' by many virologists. Fields was the senior editor for the first three editions of the textbook. After his death in 1995, subsequent editions have retained his name in the title. The sixth edition was published in 2013 by Wolters Kluwer under the Lippincott Williams & Wilkins Lippincott Williams & Wilkins (LWW) is an American imprint of the American Dutch publishing conglomerate Wolters Kluwer. It was established by the acquisition of Williams & Wilkins and its merger with J.B. Lippincott Company in 1998. Under the L ... imprint and it was edited by David M. Knipe and Peter M. Howley. Volume 1 of the s ...
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David M
David (; , "beloved one") (traditional spelling), , ''Dāwūd''; grc-koi, Δαυΐδ, Dauíd; la, Davidus, David; gez , ዳዊት, ''Dawit''; xcl, Դաւիթ, ''Dawitʿ''; cu, Давíдъ, ''Davidŭ''; possibly meaning "beloved one". was, according to the Hebrew Bible, the third king of the United Kingdom of Israel. In the Books of Samuel, he is described as a young shepherd and harpist who gains fame by slaying Goliath, a champion of the Philistines, in southern Canaan. David becomes a favourite of Saul, the first king of Israel; he also forges a notably close friendship with Jonathan, a son of Saul. However, under the paranoia that David is seeking to usurp the throne, Saul attempts to kill David, forcing the latter to go into hiding and effectively operate as a fugitive for several years. After Saul and Jonathan are both killed in battle against the Philistines, a 30-year-old David is anointed king over all of Israel and Judah. Following his rise to power, David ...
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