Pandoravirus Hades
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Pandoravirus Hades
''Pandoravirus'' is a genus of giant virus, first discovered in 2013. It is the second largest in physical size of any known viral genus. Pandoraviruses have double stranded DNA genomes, with the largest genome size (2.5 million base pairs) of any known viral genus. Discovery The discovery of Pandoraviruses by a team of French scientists, led by husband and wife Jean-Michel Claverie and Chantal Abergel, was announced in a report in the journal ''Science'' in July 2013. Other scientists had previously observed the pandoravirus particles, but owing to their enormous size they were not expected to be viruses. Patrick Scheid, a parasitologist from the Central Institute of the Bundeswehr Medical Service in Koblenz, Germany, found one in 2008, in an amoeba living in the contact lens of a woman with keratitis. Its development within the amoebal host was documented extensively. Unlike in other cases with such giant viruses, the large particles within ''Acanthamoeba'' were not mista ...
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Megavirales
''Nucleocytoviricota'' is a phylum of viruses. Members of the phylum are also known as the nucleocytoplasmic large DNA viruses (NCLDV), which serves as the basis of the name of the phylum with the suffix - for virus phylum. These viruses are referred to as nucleocytoplasmic because they are often able to replicate in both the host's cell nucleus and cytoplasm. The phylum is notable for containing the giant viruses. There are nine families of NCLDVs that all share certain genomic and structural characteristics; however, it is uncertain whether the similarities of the different families of this group have a common viral ancestor. One feature of this group is a large genome and the presence of many genes involved in DNA repair, DNA replication, transcription, and translation. Typically, viruses with smaller genomes do not contain genes for these processes. Most of the viruses in this family also replicate in both the host's nucleus and cytoplasm, thus the name nucleocytoplasmic. Th ...
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Koblenz
Koblenz (; Moselle Franconian language, Moselle Franconian: ''Kowelenz''), spelled Coblenz before 1926, is a German city on the banks of the Rhine and the Moselle, a multi-nation tributary. Koblenz was established as a Roman Empire, Roman military post by Nero Claudius Drusus, Drusus around 8 B.C. Its name originates from the Latin ', meaning "(at the) confluence". The actual confluence is today known as the "Deutsches Eck, German Corner", a symbol of the unification of Germany that features an Emperor William monuments, equestrian statue of Emperor William I. The city celebrated its 2000th anniversary in 1992. It ranks in population behind Mainz and Ludwigshafen am Rhein to be the third-largest city in Rhineland-Palatinate. Its usual-residents' population is 112,000 (as at 2015). Koblenz lies in a narrow flood plain between high hill ranges, some reaching mountainous height, and is served by an express rail and autobahn network. It is part of the populous Rhineland. History ...
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Bacteria
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the first life forms to appear on Earth, and are present in most of its habitats. Bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of Earth's crust. Bacteria are vital in many stages of the nutrient cycle by recycling nutrients such as the fixation of nitrogen from the atmosphere. The nutrient cycle includes the decomposition of dead bodies; bacteria are responsible for the putrefaction stage in this process. In the biological communities surrounding hydrothermal vents and cold seeps, extremophile bacteria provide the nutrients needed to sustain life by converting dissolved compounds, such as hydrogen sulphide and methane, to energy. Bacteria also live in symbiotic and parasitic relationsh ...
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Influenza A Virus
''Influenza A virus'' (''IAV'') causes influenza in birds and some mammals, and is the only species of the genus ''Alphainfluenzavirus'' of the virus family ''Orthomyxoviridae''. Strain (biology)#Microbiology or virology, Strains of all subtypes of influenza A virus have been isolated from wild birds, although disease is uncommon. Some primary isolate, isolates of influenza A virus cause severe disease both in domestic poultry and, rarely, in humans. Occasionally, viruses are transmitted from wild aquatic birds to domestic poultry, and this may cause an outbreak or give rise to human influenza pandemics. Influenza A viruses are Sense (molecular biology), negative-sense, single-stranded, segmented RNA viruses. The several subtypes are labeled according to an H number (for the type of Hemagglutinin (influenza), hemagglutinin) and an N number (for the type of viral neuraminidase, neuraminidase). There are 18 different known H antigens (H1 to H18) and 11 different known N antigens (N ...
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Genome
In the fields of molecular biology and genetics, a genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as regulatory sequences (see non-coding DNA), and often a substantial fraction of 'junk' DNA with no evident function. Almost all eukaryotes have mitochondria and a small mitochondrial genome. Algae and plants also contain chloroplasts with a chloroplast genome. The study of the genome is called genomics. The genomes of many organisms have been sequenced and various regions have been annotated. The International Human Genome Project reported the sequence of the genome for ''Homo sapiens'' in 200The Human Genome Project although the initial "finished" sequence was missing 8% of the genome consisting mostly of repetitive sequences. With advancements in technology that could handle sequenci ...
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Micrometre
The micrometre ( international spelling as used by the International Bureau of Weights and Measures; SI symbol: μm) or micrometer (American spelling), also commonly known as a micron, is a unit of length in the International System of Units (SI) equalling (SI standard prefix "micro-" = ); that is, one millionth of a metre (or one thousandth of a millimetre, , or about ). The nearest smaller common SI unit is the nanometre, equivalent to one thousandth of a micrometre, one millionth of a millimetre or one billionth of a metre (). The micrometre is a common unit of measurement for wavelengths of infrared radiation as well as sizes of biological cells and bacteria, and for grading wool by the diameter of the fibres. The width of a single human hair ranges from approximately 20 to . The longest human chromosome, chromosome 1, is approximately in length. Examples Between 1 μm and 10 μm: * 1–10 μm – length of a typical bacterium * 3–8 μm – width of ...
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Melbourne, Australia
Melbourne ( ; Boonwurrung/Woiwurrung: ''Narrm'' or ''Naarm'') is the capital and most populous city of the Australian state of Victoria, and the second-most populous city in both Australia and Oceania. Its name generally refers to a metropolitan area known as Greater Melbourne, comprising an urban agglomeration of 31 local municipalities, although the name is also used specifically for the local municipality of City of Melbourne based around its central business area. The metropolis occupies much of the northern and eastern coastlines of Port Phillip Bay and spreads into the Mornington Peninsula, part of West Gippsland, as well as the hinterlands towards the Yarra Valley, the Dandenong and Macedon Ranges. It has a population over 5 million (19% of the population of Australia, as per 2021 census), mostly residing to the east side of the city centre, and its inhabitants are commonly referred to as "Melburnians". The area of Melbourne has been home to Aboriginal Victorians ...
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La Trobe University
La Trobe University is a public research university based in Melbourne, Victoria, Australia. Its main campus is located in the suburb of Bundoora. The university was established in 1964, becoming the third university in the state of Victoria and the twelfth university in Australia. La Trobe is one of the Australian verdant universities and also part of the Innovative Research Universities group. La Trobe's original and principal campus is located in the Melbourne metropolitan area, within the northern Melbourne suburb of Bundoora. It is the largest metropolitan campus in the country, occupying over . It has two other major campuses located in the regional Victorian city of Bendigo and the twin border cities of Albury-Wodonga. There are two smaller regional campuses in Mildura and Shepparton and a city campus in Melbourne's CBD on Collins Street and in Sydney on Elizabeth Street. La Trobe offers undergraduate and postgraduate courses across its two colleges of Arts, Social ...
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Seawater
Seawater, or salt water, is water from a sea or ocean. On average, seawater in the world's oceans has a salinity of about 3.5% (35 g/L, 35 ppt, 600 mM). This means that every kilogram (roughly one liter by volume) of seawater has approximately of dissolved salts (predominantly sodium () and chloride () ions). The average density at the surface is 1.025 kg/L. Seawater is denser than both fresh water and pure water (density 1.0 kg/L at ) because the dissolved salts increase the mass by a larger proportion than the volume. The freezing point of seawater decreases as salt concentration increases. At typical salinity, it freezes at about . The coldest seawater still in the liquid state ever recorded was found in 2010, in a stream under an Antarctic glacier: the measured temperature was . Seawater pH is typically limited to a range between 7.5 and 8.4. However, there is no universally accepted reference pH-scale for seawater and the difference between measurement ...
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Megavirus
Megavirus is a viral genus containing a single identified species named ''Megavirus chilensis'', phylogenetically related to Acanthamoeba polyphaga Mimivirus (APMV). In colloquial speech, Megavirus chilensis is more commonly referred to as just “Megavirus”. Until the discovery of pandoraviruses in 2013, it had the largest capsid diameter of all known viruses, as well as the largest and most complex genome among all known viruses. Discovery Megavirus was isolated from a water sample collected in April 2010 off the coast of Chile, near the marine station in Las Cruces, by Jean-Michel Claverie and Chantal Abergel from the Structural & Genomic Information laboratory (IGS, CNRS and Aix-Marseille University). Megavirus was isolated by co-cultivation with a variety of ''Acanthamoeba'' laboratory strains ('' A. polyphaga'', '' A. castellanii'', '' A. griffini'') following a protocol pioneered by Timothy Rowbotham for isolating intracellular parasitic bacteria. Megavirus infects a ...
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DNA Virus
A DNA virus is a virus that has a genome made of deoxyribonucleic acid (DNA) that is replicated by a DNA polymerase. They can be divided between those that have two strands of DNA in their genome, called double-stranded DNA (dsDNA) viruses, and those that have one strand of DNA in their genome, called single-stranded DNA (ssDNA) viruses. dsDNA viruses primarily belong to two realms: ''Duplodnaviria'' and ''Varidnaviria'', and ssDNA viruses are almost exclusively assigned to the realm ''Monodnaviria'', which also includes some dsDNA viruses. Additionally, many DNA viruses are unassigned to higher taxa. Reverse transcribing viruses, which have a DNA genome that is replicated through an RNA intermediate by a reverse transcriptase, are classified into the kingdom '' Pararnavirae'' in the realm '' Riboviria''. DNA viruses are ubiquitous worldwide, especially in marine environments where they form an important part of marine ecosystems, and infect both prokaryotes and eukaryotes. The ...
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Mimivirus
''Mimivirus'' is a genus of giant viruses, in the family ''Mimiviridae''. Amoeba serve as their natural hosts. This genus contains a single identified species named ''Acanthamoeba polyphaga mimivirus'' (APMV). It also refers to a group of phylogenetically related large viruses. In colloquial speech, APMV is more commonly referred to as just "mimivirus". Mimivirus, short for "mimicking microbe", is so called to reflect its large size and apparent Gram-staining properties. Mimivirus has a large and complex genome compared with most other viruses. Until 2013, when a larger virus ''Pandoravirus'' was described, it had the largest capsid diameter of all known viruses. History APMV was discovered accidentally in 1992 within the amoeba '' Acanthamoeba polyphaga'', after which it is named, during research into legionellosis by researchers from Marseille and Leeds. The virus was observed in a Gram stain and mistakenly thought to be a Gram-positive bacterium. As a consequence it was nam ...
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