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Otto Hutter
Otto Fred Hutter (29 February 1924 – 22 November 2020) was an Austrian-born British physiologist who was Regius Professor of Physiology at the University of Glasgow. Biography Hutter was born in Vienna, Austria in February 1924. His father, Isaak, from Lviv (now in Ukraine), had joined the Austro-Hungarian army to fight in the First World War, after which he settled in Austria. He married Elisabeth Grünberg, a nurse, and worked as an estate agent. Hutter first attended secondary school at the Zwi Perez Chajes Gymnasium. He left Vienna in December 1938 as part of the Kindertransport which allowed Jewish children to escape the German annexation of Austria (the Anschluss). After arriving in the UK, he attended Bishop Stortford College as a boarder. He became a British citizen in 1947. From 1942, after leaving school, Hutter worked as a laboratory technician at the Wellcome Research Laboratories in Beckenham, Kent. One project addressed the standardisation of penicillin p ...
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Bournemouth
Bournemouth () is a coastal resort town in the Bournemouth, Christchurch and Poole council area of Dorset, England. At the 2011 census, the town had a population of 183,491, making it the largest town in Dorset. It is situated on the Southern England, English south coast, equidistant () from Dorchester, Dorset, Dorchester and Southampton. Bournemouth is part of the South East Dorset conurbation, which has a population of 465,000. Before it was founded in 1810 by Lewis Tregonwell, the area was a deserted heathland occasionally visited by fishermen and smugglers. Initially marketed as a health resort, the town received a boost when it appeared in Augustus Granville's 1841 book, ''The Spas of England''. Bournemouth's growth accelerated with the arrival of the railway, and it became a town in 1870. Part of the Historic counties of England, historic county of Hampshire, Bournemouth joined Dorset for administrative purposes following the Local Government Act 1972, reorganisation of l ...
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Bishop Stortford College
Bishop's Stortford College is a independent day and boarding school in the English public school tradition for more than 1,200 pupils aged 4–18, situated in a campus on the edge of the market town of Bishop's Stortford, Hertfordshire, England. As an " all-through" school, it is a member of both the Headmasters' and Headmistresses' Conference and the Independent Association of Preparatory Schools. It is also a founding member of the Bishop’s Stortford Educational Trust, a consortium of local primary and secondary schools, and currently the only such trust in the UK to involve both state and independent sectors. The college head is Kathy Crewe-Read. History The college was founded in 1868 by a group of prominent East Anglian Nonconformists who wanted to establish a public school "in which Evangelical Nonconformists might secure for their boys, an effective and Christian education on terms that should not be beyond the reach of the middle class generally". They approached t ...
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Acetylcholine
Acetylcholine (ACh) is an organic chemical that functions in the brain and body of many types of animals (including humans) as a neurotransmitter. Its name is derived from its chemical structure: it is an ester of acetic acid and choline. Parts in the body that use or are affected by acetylcholine are referred to as cholinergic. Substances that increase or decrease the overall activity of the cholinergic system are called cholinergics and anticholinergics, respectively. Acetylcholine is the neurotransmitter used at the neuromuscular junction—in other words, it is the chemical that motor neurons of the nervous system release in order to activate muscles. This property means that drugs that affect cholinergic systems can have very dangerous effects ranging from paralysis to convulsions. Acetylcholine is also a neurotransmitter in the autonomic nervous system, both as an internal transmitter for the sympathetic nervous system and as the final product released by the parasymp ...
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Cardiac Pacemaker
350px, Image showing the cardiac pacemaker or SA node, the primary pacemaker within the electrical_conduction_system_of_the_heart">SA_node,_the_primary_pacemaker_within_the_electrical_conduction_system_of_the_heart. The_muscle_contraction.html" "title="electrical conduction system of the heart.">electrical conduction system of the heart">SA node, the primary pacemaker within the electrical conduction system of the heart. The muscle contraction">contraction of cardiac muscle (heart muscle) in all animals is initiated by electrical impulses known as action potentials that in the heart are known as cardiac action potentials. The rate at which these impulses fire controls the rate of cardiac contraction, that is, the heart rate. The cells that create these rhythmic impulses, setting the pace for blood pumping, are called pacemaker cells, and they directly control the heart rate. They make up the cardiac pacemaker, that is, the natural pacemaker of the heart. In most humans, the h ...
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Pacemaker Potential
In the pacemaking cells of the heart (e.g., the sinoatrial node), the pacemaker potential (also called the pacemaker current) is the slow, positive increase in voltage across the cell's membrane (the membrane potential) that occurs between the end of one action potential and the beginning of the next action potential. This increase in membrane potential is what causes the cell membrane, which typically maintains a resting membrane potential around -65 mV, to reach the threshold potential and consequently fire the next action potential; thus, the pacemaker potential is what drives the self-generated rhythmic firing (automaticity) of pacemaker cells, and the rate of change (i.e., the slope) of the pacemaker potential is what determines the timing of the next action potential and thus the intrinsic firing rate of the cell. In a healthy sinoatrial node (SAN, a complex tissue within the right atrium containing pacemaker cells that normally determine the intrinsic firing rate for the enti ...
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Stephen Kuffler
Stephen William Kuffler (August 24 Táp, Austria-Hungary, 1913 – October 11, 1980) was a pre-eminent Hungarian-American neurophysiologist. He is often referred to as the "Father of Modern Neuroscience". Kuffler, alongside noted Nobel Laureates Sir John Eccles and Sir Bernard Katz gave research lectures at the University of Sydney, strongly influencing its intellectual environment while working at Sydney Hospital. He founded the Harvard Neurobiology department in 1966, and made numerous seminal contributions to our understanding of vision, neural coding, and the neural implementation of behavior. He is known for his research on neuromuscular junctions in frogs, presynaptic inhibition, and the neurotransmitter GABA. In 1972, he was awarded the Louisa Gross Horwitz Prize from Columbia University. Honors and awards Kuffler was widely recognized as a truly original and creative neuroscientist. In addition to numerous prizes, honorary degrees, and special lectureships from co ...
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Baltimore
Baltimore ( , locally: or ) is the most populous city in the U.S. state of Maryland, fourth most populous city in the Mid-Atlantic, and the 30th most populous city in the United States with a population of 585,708 in 2020. Baltimore was designated an independent city by the Constitution of Maryland in 1851, and today is the most populous independent city in the United States. As of 2021, the population of the Baltimore metropolitan area was estimated to be 2,838,327, making it the 20th largest metropolitan area in the country. Baltimore is located about north northeast of Washington, D.C., making it a principal city in the Washington–Baltimore combined statistical area (CSA), the third-largest CSA in the nation, with a 2021 estimated population of 9,946,526. Prior to European colonization, the Baltimore region was used as hunting grounds by the Susquehannock Native Americans, who were primarily settled further northwest than where the city was later built. Colonist ...
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Rockefeller Foundation
The Rockefeller Foundation is an American private foundation and philanthropic medical research and arts funding organization based at 420 Fifth Avenue, New York City. The second-oldest major philanthropic institution in America, after the Carnegie Corporation, the foundation was ranked as the 39th largest U.S. foundation by total giving as of 2015. By the end of 2016, assets were tallied at $4.1 billion (unchanged from 2015), with annual grants of $173 million. According to the OECD, the foundation provided US$103.8 million for development in 2019. The foundation has given more than $14 billion in current dollars. The foundation was started by Standard Oil magnate John D. Rockefeller ("Senior") and son "Junior", and their primary business advisor, Frederick Taylor Gates, on May 14, 1913, when its charter was granted by New York. The foundation has had an international reach since the 1930s and major influence on global non-governmental organizations. The World Health Organiza ...
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Bachelor Of Science
A Bachelor of Science (BS, BSc, SB, or ScB; from the Latin ') is a bachelor's degree awarded for programs that generally last three to five years. The first university to admit a student to the degree of Bachelor of Science was the University of London in 1860. In the United States, the Lawrence Scientific School first conferred the degree in 1851, followed by the University of Michigan in 1855. Nathaniel Southgate Shaler, who was Harvard's Dean of Sciences, wrote in a private letter that "the degree of Bachelor of Science came to be introduced into our system through the influence of Louis Agassiz, who had much to do in shaping the plans of this School." Whether Bachelor of Science or Bachelor of Arts degrees are awarded in particular subjects varies between universities. For example, an economics student may graduate as a Bachelor of Arts in one university but as a Bachelor of Science in another, and occasionally, both options are offered. Some universities follow the Oxford a ...
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Birkbeck, University Of London
, mottoeng = Advice comes over nightTranslation used by Birkbeck. , established = , type = Public research university , endowment = £4.3 m (2014) , budget = £109 million (2015) , parent = University of London , staff = , president = Baroness Bakewell , chancellor = The Princess Royal (University of London) , vice_chancellor = Wendy Thomson (University of London) , head_label = Master , head = David S Latchman , students = () , undergrad = () , postgrad = () , location = London, England, United Kingdom , coordinates = , colours = , mascot = , nickname = , affiliations = ACU European University AssociationRoyal Academy of Dramatic ArtUniversiti ...
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Chelsea College Of Arts
Chelsea College of Arts is a constituent college of the University of the Arts London based in London, United Kingdom, and is a leading British art and design institution with an international reputation. It offers further and higher education courses in fine art, graphic design, interior design, spatial design and textile design up to PhD level. History Polytechnic Chelsea College of Arts was originally an integral school of the South-Western Polytechnic, which opened at Manresa Road, Chelsea, in 1895 to provide scientific and technical education to Londoners. Day and evening classes for men and women were held in domestic economy, mathematics, engineering, natural science, art and music. Art was taught from the beginning of the Polytechnic, and included design, weaving, embroidery and electrodeposition. The South-Western Polytechnic became the Chelsea Polytechnic in 1922 and taught a growing number of registered students of the University of London. At the beginning of t ...
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Penicillin
Penicillins (P, PCN or PEN) are a group of β-lactam antibiotics originally obtained from ''Penicillium'' moulds, principally '' P. chrysogenum'' and '' P. rubens''. Most penicillins in clinical use are synthesised by P. chrysogenum using deep tank fermentation and then purified. A number of natural penicillins have been discovered, but only two purified compounds are in clinical use: penicillin G (intramuscular or intravenous use) and penicillin V (given by mouth). Penicillins were among the first medications to be effective against many bacterial infections caused by staphylococci and streptococci. They are still widely used today for different bacterial infections, though many types of bacteria have developed resistance following extensive use. 10% of the population claims penicillin allergies but because the frequency of positive skin test results decreases by 10% with each year of avoidance, 90% of these patients can tolerate penicillin. Additionally, those with ...
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