Origin Of SARS-CoV-2
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Origin Of SARS-CoV-2
Since the beginning of the COVID-19 pandemic, there have been efforts by scientists, governments, and others to determine the origin of the SARS-CoV-2 virus. Similar to other outbreaks, the virus was derived from a Bat virome, bat-borne virus and most likely was transmitted to humans zoonotic, via another animal in nature, or during wildlife trade such as that in food markets. While other explanations, such as speculations that SARS-CoV-2 was accidentally COVID-19 lab leak theory, released from a laboratory have been proposed, such explanations are not supported by evidence.https://journals.asm.org/doi/10.1128/jvi.01240-24 Conspiracy theory, Conspiracy theories about the virus's origin have also proliferated. SARS-CoV-2 has close Conserved sequence, genetic similarity to multiple previously identified bat coronaviruses, suggesting it crossed over into humans from bats. Research is ongoing as to whether SARS-CoV-2 came directly from bats or indirectly through an intermediate hos ...
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COVID-19 Pandemic
The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identified in an outbreak in the Chinese city of Wuhan in December 2019. Attempts to contain it there failed, allowing the virus to spread to other areas of Asia and later worldwide. The World Health Organization (WHO) declared the outbreak a public health emergency of international concern on 30 January 2020, and a pandemic on 11 March 2020. As of , the pandemic had caused more than cases and confirmed deaths, making it one of the deadliest in history. COVID-19 symptoms range from undetectable to deadly, but most commonly include fever, dry cough, and fatigue. Severe illness is more likely in elderly patients and those with certain underlying medical conditions. COVID-19 transmits when people breathe in air contaminated by droplets and ...
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Civet
A civet () is a small, lean, mostly nocturnal mammal native to tropical Asia and Africa, especially the tropical forests. The term civet applies to over a dozen different species, mostly from the family Viverridae. Most of the species diversity is found in southeast Asia. The best-known species is the African civet, ''Civettictis civetta'', which historically has been the main species from which a musky scent used in perfumery, also referred to as "civet", was obtained. Naming The common name is used for a variety of carnivoran mammal species, mostly of the family Viverridae. The African palm civet (''Nandinia binotata'') is genetically distinct and belongs in its own monotypic family, Nandiniidae. Civets are also called "toddycats" in English, "Mara Patti" in Malayalam, "musang" in Malay and Indonesian, and ''urulǣvā'' () in Sinhalese. There can be confusion among speakers of Malay because the indigenous word "musang" has been mistakenly applied to foxes by printed media in ...
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Nature Microbiology
''Nature Microbiology'' is a monthly online-only peer reviewed scientific journal published by Nature Portfolio. It was established in 2016. The editor-in-chief is Susan Jones who is part of an in-house team of editors. Abstracting and indexing The journal is abstracted and indexed in: * PubMed * Science Citation Index Expanded * Scopus According to the ''Journal Citation Reports'', the journal has a 2022 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 28.3. References External links Official website Nature Research academic journals Microbiology journals English-language journals Academic journals established in 2016 Monthly journals Online-only journals {{microbiology-journal-stub ...
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Feuang District
Feuang is a Districts of Laos, district of Vientiane province, Laos.Laos Ministry of Education district maps

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Districts of Laos {{Laos-geo-stub ...
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Yunnan
Yunnan , () is a landlocked Provinces of China, province in Southwest China, the southwest of the People's Republic of China. The province spans approximately and has a population of 48.3 million (as of 2018). The capital of the province is Kunming. The province borders the Chinese provinces of Guizhou, Sichuan, autonomous regions of Guangxi, and Tibet Autonomous Region, Tibet as well as Southeast Asian countries: Vietnam, Laos, and Myanmar. Yunnan is China's fourth least developed province based on disposable income per capita in 2014. Yunnan is situated in a mountainous area, with high elevations in the northwest and low elevations in the southeast. Most of the population lives in the eastern part of the province. In the west, the altitude can vary from the mountain peaks to river valleys by as much as . Yunnan is rich in natural resources and has the largest diversity of plant life in China. Of the approximately 30,000 species of Vascular plant, higher plants in China, Yu ...
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RaTG13
Bat coronavirus RaTG13 is a SARS-like betacoronavirus that infects the horseshoe bat '' Rhinolophus affinis''. It was discovered in 2013 in bat droppings from a mining cave near the town of Tongguan in Mojiang county in Yunnan, China. In February 2020, it was identified as the closest known (at the time) relative of SARS-CoV-2, the virus that causes COVID-19, sharing 96.1% nucleotide similarity. However, in 2022, scientists found three closer matches in bats found 530 km south, in Feuang, Laos, designated as BANAL-52 (96.8% similarity), BANAL-103 and BANAL-236. History In spring 2012, three miners cleaning bat feces in an abandoned copper mine near the town of Tongguan in Mojiang Hani Autonomous County developed fatal pneumonia. Out of concerns that the miner's cases could represent a novel disease, serum samples collected from the miners were sent to the Wuhan Institute of Virology and tested by Shi Zhengli and her group for Ebola virus, Nipah virus, and bat SARSr-CoV Rp3. ...
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Intermediate Horseshoe Bat
The intermediate horseshoe bat (''Rhinolophus affinis'') is a bat species of the family Rhinolophidae (“nose crest”) that is very widespread throughout much of the Indian subcontinent, southern and central China and Southeast Asia. It is listed by IUCN as Least Concern as it is considered common where it occurs, without any known major threats. Taxonomy The intermediate horseshoe bat was described as a new species in 1823 by American naturalist Thomas Horsfield. The holotype was collected on the Indonesian island of Java. ''Rhinolophus affinis'' is divided into the following nine subspecies: * ''R. a. affinis'' * ''R. a. andamanensis'' * ''R. a. hainanus'' * ''R. a. himalayanus'' * ''R. a. macrurus'' * ''R. a. nesites'' * ''R. a. princes'' * ''R. a. superans'' * ''R. a. tener'' It varies in appearance and echolocation characteristics throughout its range, suggesting that this taxon may represent a species complex of closely related species. Description The intermediat ...
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Huanan Seafood Wholesale Market
The Wuhan Huanan Seafood Wholesale Market (), simply known as the Huanan Seafood Market (''Huanan'' means 'South China'), was a live animal and seafood market in Jianghan District, Wuhan City, the capital of Hubei Province in Central China. The market became widely known worldwide after being identified as the 'Ground Zero' site of COVID-19 and the resulting pandemic. The World Health Organization was notified on 31 December 2019 about an outbreak of pneumonia in Wuhan. Of the initial 41 people hospitalized with pneumonia who were officially identified as having laboratory-confirmed SARS-CoV-2 infection by 2 January 2020, two-thirds were exposed to the market. The market was opened on 19 June 2002 and closed permanently on 1 January 2020 for sanitary procedures and disinfection. Thirty-three out of 585 environmental samples obtained from the market indicated evidence of coronavirus disease (COVID-19) outbreak, according to the Chinese Center for Disease Control and Prevention. ...
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Reuters
Reuters ( ) is a news agency owned by Thomson Reuters Corporation. It employs around 2,500 journalists and 600 photojournalists in about 200 locations worldwide. Reuters is one of the largest news agencies in the world. The agency was established in London in 1851 by the German-born Paul Reuter. It was acquired by the Thomson Corporation of Canada in 2008 and now makes up the media division of Thomson Reuters. History 19th century Paul Reuter worked at a book-publishing firm in Berlin and was involved in distributing radical pamphlets at the beginning of the Revolutions in 1848. These publications brought much attention to Reuter, who in 1850 developed a prototype news service in Aachen using homing pigeons and electric telegraphy from 1851 on, in order to transmit messages between Brussels and Aachen, in what today is Aachen's Reuters House. Reuter moved to London in 1851 and established a news wire agency at the London Royal Exchange. Headquartered in London, Reuter' ...
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2002–2004 SARS Outbreak
The 2002–2004 outbreak of SARS, caused by severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), infected over 8,000 people from 29 countries and territories, and resulted in at least 774 deaths worldwide. The outbreak was first identified in Foshan, Guangdong, China, in November 2002. The World Health Organization (WHO) was notified of the outbreak in February 2003, and issued a global alert in March 2003. Initially, the cause of the outbreak was unknown, and some media outlets reported that an influenza virus was a potential culprit. The major part of the outbreak lasted about 8 months, and the World Health Organization declared SARS contained on 5 July 2003. However, several SARS cases were reported until May 2004. In late December 2019, SARS-CoV-2, a new strain of coronavirus closely related to the one that caused SARS, was discovered in Wuhan, Hubei, China. The new strain causes COVID-19, a disease which has since spread worldwide, leading to an ongo ...
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Spillover Infection
Spillover infection, also known as pathogen spillover and spillover event, occurs when a reservoir population with a high pathogen prevalence comes into contact with a novel host population. The pathogen is transmitted from the reservoir population and may or may not be transmitted within the host population. Due to climate change and land use expansion, the risk of viral spillover is predicted to significantly increase. Spillover zoonoses Spillover is a common event; in fact, more than two-thirds of human viruses are zoonotic. Most spillover events result in self-limited cases with no further human to human transmission, as occurs, for example, with rabies, anthrax, histoplasmosis or hidatidosis. Other zoonotic pathogens are able to be transmitted by humans to produce secondary cases and even to establish limited chains of transmission. Some examples are the Ebola and Marburg filoviruses, COVID-19, the MERS and SARS coronaviruses or some avian flu viruses. Finally, some few spil ...
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