Nyamiviridae
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Nyamiviridae
''Nyamiviridae'' is a family of negative-strand RNA viruses in the order ''Mononegavirales''. Ecdysozoa and birds serve as natural hosts. The name is a portmanteau of ''Nya''manini Pan (place of isolation of type species Nyamanini virus in South Africa) and ''Mi''dway Atoll (place of isolation of Midway virus in the United States) and the suffix -''viridae'' used to denote a virus family. There are seven genera in this family. History Nyamanini virus (NYMV) and Midway virus (MDWV) were first isolated in 1957 and 1966 respectively. NYMV has been isolated from cattle egrets (species ''Bubulcus ibis'') and ticks (species '' Argas walkerae'') in Egypt, India, Nigeria, South Africa, and Thailand. MDWV has been isolated from ticks of the genus ''Ornithodoros'' collected in Midway, Kure and Manana islands and northern Honshu, Japan. Antibodies to this virus have been found in the black-tailed gull (species '' Larus crassirostris'') and black-crowned night heron (species ''Nyctico ...
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Mononegavirales
''Mononegavirales'' is an order of negative-strand RNA viruses which have nonsegmented genomes. Some common members of the order are Ebola virus, human respiratory syncytial virus, measles virus, mumps virus, Nipah virus, and rabies virus. All of these viruses cause significant disease in humans. Many other important pathogens of nonhuman animals and plants are also in the group. The order includes eleven virus families: '' Artoviridae'', ''Bornaviridae'', ''Filoviridae'', ''Lispiviridae'', ''Mymonaviridae'', ''Nyamiviridae'', ''Paramyxoviridae'', ''Pneumoviridae'', ''Rhabdoviridae'', '' Sunviridae'', and ''Xinmoviridae''. Use of term The order ''Mononegavirales'' (pronounced: ) According to the rules for taxon naming established by the International Committee on Taxonomy of Viruses (ICTV), the name ''Mononegavirales'' is always to be capitalized, italicized, and never abbreviated. The names of the order's physical members ("mononegaviruses" or "mononegavirads") are to be writte ...
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Nyavirus
''Nyavirus'' is a genus of negative-strand RNA viruses in the family ''Nyamiviridae''. Ticks and birds serve as natural hosts. There are four species in this genus. History ''Nyamanini nyavirus'' (NYMV) and ''Midway nyavirus (''MDWV) were first isolated in 1957 and 1966 respectively. NYMV has been isolated from cattle egrets (species ''Bubulcus ibis'') and ticks (species '' Argas walkerae'') in Egypt, India, Nigeria, South Africa, and Thailand. MDWV has been isolated from tick of the genus ''Ornithodoros'' collected in Midway, Kure and Manana islands and northern Honshu, Japan. Antibodies to this virus have been found in the black-tailed gulls (species '' Larus crassirostris'') and black-crowned night herons (species ''Nycticorax nycticorax''). Structure Nyaviruses are enveloped, with spherical geometries. The diameter is around 100 to 130 nm. Genomes are linear, nonsegmented, and around 11.6 kbp in total length. The genome codes for 6 proteins. Their genomes contain si ...
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Kure
is a port and major shipbuilding city situated on the Seto Inland Sea in Hiroshima Prefecture, Japan. With a strong industrial and naval heritage, Kure hosts the second-oldest naval dockyard in Japan and remains an important base for the Japan Maritime Self-Defence Force (JMSDF) named, JMSDF Kure Naval Base. , the city has an estimated population of 228,030 and a population density of 646 persons per km2. The total area is 352.80 km2. History The Kure Naval District was first established in 1889, leading to the construction of the Kure Naval Arsenal and the rapid growth of steel production and shipbuilding in the city. Kure was formally incorporated on October 1, 1902. From 1889 until the end of World War II, the city served as the headquarters of the Kure Naval District. Kure dockyards recorded a number of significant engineering firsts including the launching of the first major domestically built capital ship, the battlecruiser ''Tsukuba'' (1905) and the launching of ...
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RNA-dependent RNA Polymerase
RNA-dependent RNA polymerase (RdRp) or RNA replicase is an enzyme that catalyzes the replication of RNA from an RNA template. Specifically, it catalyzes synthesis of the RNA strand complementary to a given RNA template. This is in contrast to typical DNA-dependent RNA polymerases, which all organisms use to catalyze the transcription of RNA from a DNA template. RdRp is an essential protein encoded in the genomes of most RNA-containing viruses with no DNA stage including SARS-CoV-2. Some eukaryotes also contain RdRps, which are involved in RNA interference and differ structurally from viral RdRps. History Viral RdRps were discovered in the early 1960s from studies on mengovirus and polio virus when it was observed that these viruses were not sensitive to actinomycin D, a drug that inhibits cellular DNA-directed RNA synthesis. This lack of sensitivity suggested that there is a virus-specific enzyme that could copy RNA from an RNA template and not from a DNA template. Distr ...
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Capsid
A capsid is the protein shell of a virus, enclosing its genetic material. It consists of several oligomeric (repeating) structural subunits made of protein called protomers. The observable 3-dimensional morphological subunits, which may or may not correspond to individual proteins, are called capsomeres. The proteins making up the capsid are called capsid proteins or viral coat proteins (VCP). The capsid and inner genome is called the nucleocapsid. Capsids are broadly classified according to their structure. The majority of the viruses have capsids with either helical or icosahedral structure. Some viruses, such as bacteriophages, have developed more complicated structures due to constraints of elasticity and electrostatics. The icosahedral shape, which has 20 equilateral triangular faces, approximates a sphere, while the helical shape resembles the shape of a spring, taking the space of a cylinder but not being a cylinder itself. The capsid faces may consist of one or more ...
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Nycticorax Nycticorax
The black-crowned night heron (''Nycticorax nycticorax''), or black-capped night heron, commonly shortened to just night heron in Eurasia, is a medium-sized heron found throughout a large part of the world, including parts of Europe, Asia, and North and South America. In Australasia it is replaced by the closely related nankeen night heron, with which it has hybridized in the area of contact. Taxonomy The black-crowned night heron was formally described by the Swedish naturalist Carl Linnaeus in 1758 in the tenth edition of his ''Systema Naturae''. He placed it with herons, cranes and egrets in the genus '' Ardea'' and coined the binomial name ''Ardea nicticorax''. It is now placed in the genus ''Nycticorax'' that was introduced in 1817 by the English naturalist Thomas Forster for this species. The epithet ''nycticorax'' is from Ancient Greek and combines ''nux'', ''nuktos'' meaning "night" and ''korax'' meaning "raven". The word was used by authors such as Aristotle and Hesy ...
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