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Novel Coronavirus
Novel coronavirus (nCoV) is a provisional name given to coronaviruses of medical significance before a permanent name is decided upon. Although coronaviruses are endemic in humans and infections normally mild, such as the common cold (caused by human coronaviruses in ~15% of cases), cross-species transmission has produced some unusually virulent strains which can cause viral pneumonia and in serious cases even acute respiratory distress syndrome and death. Species The following viruses could initially be referred to as "novel coronavirus", before being formally named: All four viruses are part of the '' Betacoronavirus'' genus within the coronavirus family. Etymology The word "novel" indicates a "new pathogen of a previously known type" (''i.e.'' known family) of virus. Use of the word conforms to best practices for naming new infectious diseases published by the World Health Organization (WHO) in 2015. Historically, pathogens have sometimes been named after locations, indi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coronaviridae
''Coronaviridae'' is a family of enveloped, positive-strand RNA viruses which infect amphibians, birds, and mammals. The group includes the subfamilies '' Letovirinae'' and ''Orthocoronavirinae;'' the members of the latter are known as coronaviruses. The viral genome is 26–32 kilobases in length. The particles are typically decorated with large (~20 nm), club- or petal-shaped surface projections (the " peplomers" or "spikes"), which in electron micrographs of spherical particles create an image reminiscent of the solar corona. Virology The 5' and 3' ends of the genome have a cap and poly(A) tract, respectively. The viral envelope, obtained by budding through membranes of the endoplasmic reticulum (ER) or Golgi apparatus, invariably contains two virus-specified glycoprotein species, known as the spike (S) and membrane (M) proteins. The spike protein makes up the large surface projections (sometimes known as peplomers), while the membrane protein is a triple-spanning ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
COVID-19
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first known case was identified in Wuhan, China, in December 2019. The disease quickly spread worldwide, resulting in the COVID-19 pandemic. The symptoms of COVID‑19 are variable but often include fever, cough, headache, fatigue, breathing difficulties, loss of smell, and loss of taste. Symptoms may begin one to fourteen days after exposure to the virus. At least a third of people who are infected do not develop noticeable symptoms. Of those who develop symptoms noticeable enough to be classified as patients, most (81%) develop mild to moderate symptoms (up to mild pneumonia), while 14% develop severe symptoms (dyspnea, hypoxia, or more than 50% lung involvement on imaging), and 5% develop critical symptoms (respiratory failure, shock, or multiorgan dysfunction). Older people are at a higher risk of developing se ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Severe Acute Respiratory Syndrome
Severe acute respiratory syndrome (SARS) is a viral respiratory disease of zoonotic origin caused by the severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), the first identified strain of the SARS coronavirus species, ''severe acute respiratory syndrome–related coronavirus'' (SARSr-CoV). The first known cases occurred in November 2002, and the syndrome caused the 2002–2004 SARS outbreak. In the 2010s, Chinese scientists traced the virus through the intermediary of Asian palm civets to cave-dwelling horseshoe bats in Xiyang Yi Ethnic Township, Yunnan.The locality was referred to be "a cave in Kunming" in earlier sources because the Xiyang Yi Ethnic Township is administratively part of Kunming, though 70 km apart. Xiyang was identified on * For an earlier interview of the researchers about the locality of the caves, see: SARS was a relatively rare disease; at the end of the epidemic in June 2003, the incidence was 8,469 cases with a case fatality rat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Masked Palm Civet
The masked palm civet (''Paguma larvata''), also called the gem-faced civet, is a palm civet species native to the Indian subcontinent and Southeast Asia. It has been listed as least concern on the IUCN Red List since 2008 as it occurs in many protected areas, is tolerant to some degree of habitat modification, and widely distributed with presumed large populations that are unlikely to be declining. The genus ''Paguma'' was first named and described by John Edward Gray in 1831. All described forms are regarded as a single species. In 2003, masked palm civets at a wildlife market in China were found to have been infected with the severe acute respiratory syndrome coronavirus. Characteristics The masked palm civet's fur is grayish to ochraceous, black on the head, shoulders and neck, and blackish brown on the tail and feet. It has a white blaze on the forehead; white marks above and below the eyes extend to the ears, forming a half-collar. In morphology the masked palm civet ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Severe Acute Respiratory Syndrome Coronavirus 1
Severe acute respiratory syndrome coronavirus 1 (SARS-CoV-1; or Severe acute respiratory syndrome coronavirus, SARS-CoV) is a strain of coronavirus that causes severe acute respiratory syndrome (SARS), the respiratory illness responsible for the 2002–2004 SARS outbreak. It is an enveloped, positive-sense, single-stranded RNA virus that infects the epithelial cells within the lungs. The virus enters the host cell by binding to angiotensin-converting enzyme 2. It infects humans, bats, and palm civets. On April 16, 2003, following the outbreak of SARS in Asia and secondary cases elsewhere in the world, the World Health Organization (WHO) issued a press release stating that the coronavirus identified by a number of laboratories was the official cause of SARS. The Centers for Disease Control and Prevention (CDC) in the United States and the National Microbiology Laboratory (NML) in Canada identified the SARS-CoV-1 genome in April 2003. Scientists at Erasmus University in Ro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coronavirus Respiratory Syndrome
Coronavirus diseases are caused by viruses in the coronavirus subfamily, a group of related RNA viruses that cause diseases in mammals and birds. In humans and birds, the group of viruses cause respiratory tract infections that can range from mild to lethal. Mild illnesses in humans include some cases of the common cold (which is also caused by other viruses, predominantly rhinoviruses), while more lethal varieties can cause SARS, MERS and COVID-19. As of 2021, 45 species are registered as coronaviruses, whilst 11 diseases have been identified, as listed below. Coronaviruses are known for their shape resembling a stellar corona, such as that of the Sun visible during a total solar eclipse; ''corona'' is derived from the Latin word , meaning 'garland, wreath, crown'. It was coined by Tony Waterson (professor of virology at St Thomas' Hospital) in a meeting with his colleagues June Almeida and David Tyrrell, the founding fathers of coronavirus studies, and was first used ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Common Cold
The common cold or the cold is a viral infectious disease of the upper respiratory tract that primarily affects the respiratory mucosa of the nose, throat, sinuses, and larynx. Signs and symptoms may appear fewer than two days after exposure to the virus. These may include coughing, sore throat, runny nose, sneezing, headache, and fever. People usually recover in seven to ten days, but some symptoms may last up to three weeks. Occasionally, those with other health problems may develop pneumonia. Well over 200 virus strains are implicated in causing the common cold, with rhinoviruses, coronaviruses, adenoviruses and enteroviruses being the most common. They spread through the air during close contact with infected people or indirectly through contact with objects in the environment, followed by transfer to the mouth or nose. Risk factors include going to child care facilities, not sleeping well, and psychological stress. The symptoms are mostly due to the body's i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mouse
A mouse ( : mice) is a small rodent. Characteristically, mice are known to have a pointed snout, small rounded ears, a body-length scaly tail, and a high breeding rate. The best known mouse species is the common house mouse (''Mus musculus''). Mice are also popular as pets. In some places, certain kinds of field mice are locally common. They are known to invade homes for food and shelter. Mice are typically distinguished from rats by their size. Generally, when a muroid rodent is discovered, its common name includes the term ''mouse'' if it is smaller, or ''rat'' if it is larger. The common terms ''rat'' and ''mouse'' are not taxonomically specific. Typical mice are classified in the genus ''Mus'', but the term ''mouse'' is not confined to members of ''Mus'' and can also apply to species from other genera such as the deer mouse, ''Peromyscus''. Domestic mice sold as pets often differ substantially in size from the common house mouse. This is attributable to breeding a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Coronavirus HKU1
''Human coronavirus HKU1'' (''HCoV-HKU1'') is a species of coronavirus in humans and animals. It causes an upper respiratory disease with symptoms of the common cold, but can advance to pneumonia and bronchiolitis. It was first discovered in January 2004 from one man in Hong Kong. Subsequent research revealed it has global distribution and earlier genesis. The virus is an enveloped, positive-sense, single-stranded RNA virus which enters its host cell by binding to the N-acetyl-9-O-acetylneuraminic acid receptor. It has the Hemagglutinin esterase (HE) gene, which distinguishes it as a member of the genus ''Betacoronavirus'' and subgenus ''Embecovirus''. History HCoV-HKU1 was first detected in January 2004, in a 71-year-old man who was hospitalized due to acute respiratory distress syndrome and radiographically confirmed bilateral pneumonia. The man had recently returned to Hong Kong from Shenzhen, China. Virology Woo and coworkers were unsuccessful in their attempts to grow ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Middle East Respiratory Syndrome
Middle East respiratory syndrome (MERS) is a viral respiratory infection caused by ''Middle East respiratory syndrome–related coronavirus'' (MERS-CoV). Symptoms may range from none, to mild, to severe. Typical symptoms include fever, cough, diarrhea, and shortness of breath. The disease is typically more severe in those with other health problems. The first case was identified in June 2012 by Egyptian physician Ali Mohamed Zaki at the Dr. Soliman Fakeeh Hospital in Jeddah, Saudi Arabia, and most cases have occurred in the Arabian Peninsula. Over 2,500 cases have been reported as of January 2021, including 45 cases in the year 2020. About 35% of those who are diagnosed with the disease die from it. Larger outbreaks have occurred in South Korea in 2015 and in Saudi Arabia in 2018. MERS-CoV is a coronavirus believed to be originally from bats. However, humans are typically infected from camels, either during direct contact or indirectly. Spread between humans typically ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vespertilionidae
Vespertilionidae is a family of microbats, of the order Chiroptera, flying, insect-eating mammals variously described as the common, vesper, or simple nosed bats. The vespertilionid family is the most diverse and widely distributed of bat families, specialised in many forms to occupy a range of habitats and ecological circumstances, and it is frequently observed or the subject of research. The facial features of the species are often simple, as they mainly rely on vocally emitted echolocation. The tails of the species are enclosed by the lower flight membranes between the legs. Over 300 species are distributed all over the world, on every continent except Antarctica. It owes its name to the genus '' Vespertilio'', which takes its name from a word for bat, ', derived from the Latin term ' meaning 'evening'; they are termed "evening bats" and were once referred to as "evening birds". (The term "evening bat" also often refers more specifically to one of the species, '' Nycticeius hum ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dromedary
The dromedary (''Camelus dromedarius'' or ;), also known as the dromedary camel, Arabian camel, or one-humped camel, is a large even-toed ungulate, of the genus ''Camelus'', with one hump on its back. It is the tallest of the three species of camel; adult males stand at the shoulder, while females are tall. Males typically weigh between , and females weigh between . The species' distinctive features include its long, curved neck, narrow chest, a single hump (compared with two on the Bactrian camel and wild Bactrian camel), and long hairs on the throat, shoulders and hump. The coat is generally a shade of brown. The hump, tall or more, is made of fat bound together by fibrous tissue. Dromedaries are mainly active during daylight hours. They form herds of about 20 individuals, which are led by a dominant male. They feed on foliage and desert vegetation; several adaptations, such as the ability to tolerate losing more than 30% of its total water content, allow it to thriv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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