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Notolegia
Exafroplacentalia or Notolegia is a clade of placental mammals proposed in 2001 on the basis of molecular research. Exafroplacentalia places Xenarthra as a sister group to the Boreoeutheria (comprising Laurasiatheria and Euarchontoglires), thus making Afrotheria a primitive group of placental mammals (the group name roughly means "those which are not African placentals"). Classification However, this classification makes the autapomorphy (character shared only among Exafroplacentalia) dubious: it is hard to classify a group by the absence of a feature (in this case "not coming from Africa").Nishihara, H., Maruyama, S. & Okada, N. 2009. Retroposon analysis and recent geological data suggest near-simultaneous divergence of the three superorders of placental mammals. PNAS 106: 5235-40. Hence, several alternative hypotheses can be considered. Alternative hypotheses One alternative hypothesis is the Epitheria hypothesis: Another alternative hypothesis is the Atlantogenata hypo ...
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Atlantogenata
Atlantogenata is a proposed clade of mammals containing the cohorts or superorders Xenarthra and Afrotheria. These groups originated and radiated in the South American and African continents, respectively, presumably in the Cretaceous. Together with Boreoeutheria, they make up Eutheria. The monophyly of this grouping was supported by some genetic evidence. Alternative hypotheses are that Boreoeutheria and Afrotheria combine to form Epitheria (as generally supported by anatomical and other physiological evidence) or that Boreoeutheria and Xenarthra combine to form Exafroplacentalia or Notolegia. Updated analysis of transposable element A transposable element (TE, transposon, or jumping gene) is a nucleic acid sequence in DNA that can change its position within a genome, sometimes creating or reversing mutations and altering the cell's genetic identity and genome size. Transp ... insertions around the time of divergence strongly supports the fourth hypothesis of a near-conco ...
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Epitheria
Epitherians comprise all the placental mammals except the Xenarthra. They are primarily characterized by having a stirrup-shaped stapes in the middle ear, which allows for passage of a blood vessel. This is in contrast to the column-shaped stapes found in marsupials, monotremes, and xenarthrans. They are also characterized by having a shorter fibula relative to the tibia. Epitheria like Xenarthra and Afrotheria originated after the K-Pg boundary , with the placental diversification occurring within the first hundred thousand years after the K-Pg event and the first modern placental orders began appearing 2–3 million years later. Epitheres are one of the most successful groups of animals. The monophyly of Epitheria has been challenged by molecular phylogenetic studies. While preliminary analysis of a set of retroposons shared by both Afrotheria, and Boreoeutheria ( presence/absence data) supported the Epitheria clade, more extensive analysis of such transposable element insert ...
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Paleocene
The Paleocene, ( ) or Palaeocene, is a geological epoch (geology), epoch that lasted from about 66 to 56 mya (unit), million years ago (mya). It is the first epoch of the Paleogene Period (geology), Period in the modern Cenozoic Era (geology), Era. The name is a combination of the Ancient Greek ''palaiós'' meaning "old" and the Eocene Epoch (which succeeds the Paleocene), translating to "the old part of the Eocene". The epoch is bracketed by two major events in Earth's history. The K–Pg extinction event, brought on by Chicxulub impact, an asteroid impact and possibly volcanism, marked the beginning of the Paleocene and killed off 75% of living species, most famously the non-avian dinosaurs. The end of the epoch was marked by the Paleocene–Eocene Thermal Maximum (PETM), which was a major climatic event wherein about 2,500–4,500 gigatons of carbon were released into the atmosphere and ocean systems, causing a spike in global temperatures and ocean acidification. In the Pal ...
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Eutheria
Eutheria (; from Greek , 'good, right' and , 'beast'; ) is the clade consisting of all therian mammals that are more closely related to placentals than to marsupials. Eutherians are distinguished from noneutherians by various phenotypic traits of the feet, ankles, jaws and teeth. All extant eutherians lack epipubic bones, which are present in all other living mammals (marsupials and monotremes). This allows for expansion of the abdomen during pregnancy. The oldest-known eutherian species is '' Juramaia sinensis'', dated at from the early Late Jurassic ( Oxfordian) of China. Eutheria was named in 1872 by Theodore Gill; in 1880 Thomas Henry Huxley defined it to encompass a more broadly defined group than Placentalia. Characteristics Distinguishing features are: *an enlarged malleolus ("little hammer") at the bottom of the tibia, the larger of the two shin bones *the joint between the first metatarsal bone and the entocuneiform bone (the innermost of the three cuneiform ...
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Proceedings Of The National Academy Of Sciences Of The United States Of America
''Proceedings of the National Academy of Sciences of the United States of America'' (often abbreviated ''PNAS'' or ''PNAS USA'') is a peer-reviewed multidisciplinary scientific journal. It is the official journal of the National Academy of Sciences, published since 1915, and publishes original research, scientific reviews, commentaries, and letters. According to ''Journal Citation Reports'', the journal has a 2021 impact factor of 12.779. ''PNAS'' is the second most cited scientific journal, with more than 1.9 million cumulative citations from 2008 to 2018. In the mass media, ''PNAS'' has been described variously as "prestigious", "sedate", "renowned" and "high impact". ''PNAS'' is a delayed open access journal, with an embargo period of six months that can be bypassed for an author fee ( hybrid open access). Since September 2017, open access articles are published under a Creative Commons license. Since January 2019, ''PNAS'' has been online-only, although print issues are ava ...
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PLOS Genetics
''PLOS Genetics'' is a peer-reviewed open access scientific journal established in 2005 and published by the Public Library of Science. The founding editor-in-chief was Wayne N. Frankel (Columbia University Medical Center). The current editors-in-chief are Gregory S. Barsh ( HudsonAlpha Institute of Biotechnology and Stanford University School of Medicine) and Gregory P. Copenhaver (The University of North Carolina at Chapel Hill). The journal covers research on all aspects of genetics and genomics. Abstracting and indexing The journal is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 5.917. Research Prize Since its tenth year of publication, the journal annuall ...
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Genome Research
''Genome Research'' is a peer-reviewed scientific journal published by Cold Spring Harbor Laboratory Press. Disregarding review journals, Genome Research ranks 2nd in the category 'Genetics and Genomics' after Nature Genetics. The focus of the journal is on research that provides novel insights into the genome biology of all organisms, including advances in genomic medicine. This scope includes genome structure and function, comparative genomics, molecular evolution, genome-scale quantitative and population genetics, proteomics, epigenomics, and systems biology. The journal also features interesting gene discoveries and reports of cutting-edge computational biology and high-throughput biology methodologies. New data in these areas are published as research papers, or methods and resource reports that provide novel information on technologies or tools that will be of interest to a broad readership. The journal was established in 1991 as ''PCR Methods and Applications'' and obtaine ...
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Transposable Element
A transposable element (TE, transposon, or jumping gene) is a nucleic acid sequence in DNA that can change its position within a genome, sometimes creating or reversing mutations and altering the cell's genetic identity and genome size. Transposition often results in duplication of the same genetic material. Barbara McClintock's discovery of them earned her a Nobel Prize in 1983. Its importance in personalized medicine is becoming increasingly relevant, as well as gaining more attention in data analytics given the difficulty of analysis in very high dimensional spaces. Transposable elements make up a large fraction of the genome and are responsible for much of the mass of DNA in a eukaryotic cell. Although TEs are selfish genetic elements, many are important in genome function and evolution. Transposons are also very useful to researchers as a means to alter DNA inside a living organism. There are at least two classes of TEs: Class I TEs or retrotransposons generally functi ...
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Afrotheria
Afrotheria ( from Latin ''Afro-'' "of Africa" + ''theria'' "wild beast") is a clade of mammals, the living members of which belong to groups that are either currently living in Africa or of African origin: golden moles, elephant shrews (also known as sengis), tenrecs, aardvarks, hyraxes, elephants, sea cows, and several extinct clades. Most groups of afrotheres share little or no superficial resemblance, and their similarities have only become known in recent times because of genetics and molecular studies. Many afrothere groups are found mostly or exclusively in Africa, reflecting the fact that Africa was an island continent from the Cretaceous until the early Miocene around 20 million years ago, when Afro-Arabia collided with Eurasia. Because Africa was isolated by water, Laurasian groups of mammals such as insectivores, rodents, lagomorphs, carnivorans and ungulates could not reach Africa for much of the early to mid-Cenozoic. Instead, the niches occupied by those groups on the ...
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Cladistics (journal)
''Cladistics'' is a bimonthly peer-reviewed scientific journal which has published research in cladistics since 1985. It is published by Wiley-Blackwell on behalf of the Willi Hennig Society. ''Cladistics'' publishes papers relevant to evolution, systematics, and integrative biology. Papers of both a conceptual or philosophical nature, discussions of methodology, empirical studies on taxonomic groups from animals to bacteria, and applications of systematics in disciplines such as genomics, paleontology and biomedical epidemiology are accepted. Five types of paper appear in the journal: reviews, regular papers, forum papers, letters to the editor, and book reviews. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor of 5.254, ranking it 10th out of 50 journals in the category "Evolutionary Biology". Its editor-in-chief An editor-in-chief (EIC), also known as lead editor or chief editor, is a publication's editorial leader who has final responsibi ...
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Holocene
The Holocene ( ) is the current geological epoch. It began approximately 11,650 cal years Before Present (), after the Last Glacial Period, which concluded with the Holocene glacial retreat. The Holocene and the preceding Pleistocene together form the Quaternary period. The Holocene has been identified with the current warm period, known as MIS 1. It is considered by some to be an interglacial period within the Pleistocene Epoch, called the Flandrian interglacial.Oxford University Press – Why Geography Matters: More Than Ever (book) – "Holocene Humanity" section https://books.google.com/books?id=7P0_sWIcBNsC The Holocene corresponds with the rapid proliferation, growth and impacts of the human species worldwide, including all of its written history, technological revolutions, development of major civilizations, and overall significant transition towards urban living in the present. The human impact on modern-era Earth and its ecosystems may be considered of global si ...
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Placentalia
Placental mammals (infraclass Placentalia ) are one of the three extant subdivisions of the class Mammalia, the other two being Monotremata and Marsupialia. Placentalia contains the vast majority of extant mammals, which are partly distinguished from monotremes and marsupials in that the fetus (biology), fetus is carried in the uterus of its mother to a relatively late stage of development. The name is something of a misnomer considering that marsupials also nourish their fetuses via a placenta, though for a relatively briefer period, giving birth to less developed young which are then nurtured for a period inside the mother's pouch (marsupial), pouch. Anatomical features Placental mammals are anatomically distinguished from other mammals by: * a sufficiently wide opening at the bottom of the pelvis to allow the birth of a large baby relative to the size of the mother. * the absence of epipubic bones extending forward from the pelvis, which are found in all other mammals. (Their ...
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