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Nigel Scrutton
Nigel Shaun Scrutton (born 2 April 1964) is a British biochemist and biotechnology innovator known for his work on enzyme catalysis, biophysics and synthetic biology. He is Director of the UK Future Biomanufacturing Research Hub, Director of the Fine and Speciality Chemicals Synthetic Biology Research Centre (SYNBIOCHEM), and Co-founder, Director and Chief Scientific Officer of the 'fuels-from-biology' company C3 Biotechnologies Ltd. He is Professor of Enzymology and Biophysical Chemistry in the Department of Chemistry at the University of Manchester. He is former Director of the Manchester Institute of Biotechnology (MIB) (2010 to 2020). Early life and education Scrutton was born in Batley, West Riding of Yorkshire and was brought up in Cleckheaton where he went to Whitcliffe Mount School. Scrutton graduated from King's College London with a first class Bachelor of Science degree in Biochemistry in 1985. He was a Benefactors' Scholar at St John's College, Cambridge where he c ...
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Batley
Batley is a market town in the Metropolitan Borough of Kirklees, in West Yorkshire, England. Batley lies south-west of Leeds, north-west of Wakefield and Dewsbury, south-east of Bradford and north-east of Huddersfield. Batley is part of the Heavy Woollen District. In 2011 the population of Batley including Hanging Heaton, Staincliffe, Carlinghow, Birstall, Birstall Smithies, Copley Hill and Howden Clough was 48,730. ''Select "Batley M.B." from "Available Areas"'' History Batley is recorded in the ''Domesday Book'' as 'Bateleia'. After the Norman conquest, the manor was granted to Elbert de Lacy and in 1086 was within the wapentake of Morley. It subsequently passed into the ownership of the de Batleys, and by the 12th century had passed by marriage to the Copley family. Their residence at Batley Hall was held directly from the Crown; at this time the district was part of the Duchy of Lancaster. Howley Hall in Soothill was built during the 1580s by Sir John Savile, a member ...
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Biophysics
Biophysics is an interdisciplinary science that applies approaches and methods traditionally used in physics to study biological phenomena. Biophysics covers all scales of biological organization, from molecular to organismic and populations. Biophysical research shares significant overlap with biochemistry, molecular biology, physical chemistry, physiology, nanotechnology, bioengineering, computational biology, biomechanics, developmental biology and systems biology. The term ''biophysics'' was originally introduced by Karl Pearson in 1892.Roland Glaser. Biophysics: An Introduction'. Springer; 23 April 2012. . The term ''biophysics'' is also regularly used in academia to indicate the study of the physical quantities (e.g. electric current, temperature, stress, entropy) in biological systems. Other biological sciences also perform research on the biophysical properties of living organisms including molecular biology, cell biology, chemical biology, and biochemistry. Overview ...
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Churchill College
Churchill College is a constituent college of the University of Cambridge, England. It has a primary focus on science, engineering and technology, but still retains a strong interest in the arts and humanities. In 1958, a trust was established with Sir Winston Churchill as its chairman of trustees, to build and endow a college for 60 fellows and 540 students as a national and Commonwealth memorial to Winston Churchill; its Royal Charter and Statutes were approved by the Queen, in August 1960. It is situated on the outskirts of Cambridge, away from the traditional centre of the city, but close to the University's main new development zone (which now houses the Centre for Mathematical Sciences). It has of grounds, the largest area of the Cambridge colleges. Churchill was the first formerly all-male college to decide to admit women, and was among three men's colleges to admit its first women students in 1972. Within 15 years all others had followed suit. The college has a rep ...
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St John's College, Cambridge
St John's College is a Colleges of the University of Cambridge, constituent college of the University of Cambridge founded by the House of Tudor, Tudor matriarch Lady Margaret Beaufort. In constitutional terms, the college is a charitable corporation established by a charter dated 9 April 1511. The full, formal name of the college is the College of St John the Evangelist in the University of Cambridge. The aims of the college, as specified by its statutes, are the promotion of education, religion, learning and research. It is one of the larger Oxbridge colleges in terms of student numbers. For 2022, St John's was ranked 6th of 29 colleges in the Tompkins Table (the annual league table of Cambridge colleges) with over 35 per cent of its students earning British undergraduate degree classification#Degree classification, first-class honours. College alumni include the winners of twelve Nobel Prizes, seven prime ministers and twelve archbishops of various countries, at least two pri ...
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Biochemistry
Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and metabolism. Over the last decades of the 20th century, biochemistry has become successful at explaining living processes through these three disciplines. Almost all areas of the life sciences are being uncovered and developed through biochemical methodology and research. Voet (2005), p. 3. Biochemistry focuses on understanding the chemical basis which allows biological molecules to give rise to the processes that occur within living cells and between cells,Karp (2009), p. 2. in turn relating greatly to the understanding of tissues and organs, as well as organism structure and function.Miller (2012). p. 62. Biochemistry is closely related to molecular biology, which is the study of the molecular mechanisms of biological phenomena.As ...
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Bachelor Of Science
A Bachelor of Science (BS, BSc, SB, or ScB; from the Latin ') is a bachelor's degree awarded for programs that generally last three to five years. The first university to admit a student to the degree of Bachelor of Science was the University of London in 1860. In the United States, the Lawrence Scientific School first conferred the degree in 1851, followed by the University of Michigan in 1855. Nathaniel Southgate Shaler, who was Harvard's Dean of Sciences, wrote in a private letter that "the degree of Bachelor of Science came to be introduced into our system through the influence of Louis Agassiz, who had much to do in shaping the plans of this School." Whether Bachelor of Science or Bachelor of Arts degrees are awarded in particular subjects varies between universities. For example, an economics student may graduate as a Bachelor of Arts in one university but as a Bachelor of Science in another, and occasionally, both options are offered. Some universities follow the Oxford a ...
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Whitcliffe Mount School
Whitcliffe Mount School is a mixed secondary school located in Cleckheaton, West Yorkshire, England. History It was established as Cleckheaton Secondary School in 1908 in temporary premises on Brooke Street. The school moved to its current location in the town in 1910 and was renamed Cleckheaton Secondary and Technical School. Under the Education Act 1944 the school became Whitcliffe Mount Grammar School, and when the school became comprehensive in 1973 it was renamed Whitcliffe Mount School. Previously a voluntary controlled school administered by Kirklees Metropolitan Borough Council, in September 2022 Whitcliffe Mount School converted to academy status. The school is now sponsored by the SHARE Multi Academy Trust. Academics Whitcliffe Mount School offers GCSEs, BTECs and OCR Nationals as programmes of study for pupils. Notable former pupils * Wendy Holden, writer and novelist * Sarah Holt, athlete * Paul Whitaker, cricketer * Nigel Scrutton, academic and biotechnology i ...
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Cleckheaton
Cleckheaton is a town in the Metropolitan borough of Kirklees, in West Yorkshire, England. Historically part of the West Riding of Yorkshire, it is situated south of Bradford, east of Brighouse, west of Batley and south-west of Leeds. It is at the centre of the Spen Valley and was the major town in the former borough of Spenborough. Cleckheaton has a history as a mill town and forms part of the Heavy Woollen District. History Early history The Spen Valley was once heavily wooded. Evidence of human habitation in Mesolithic and Neolithic times has been found in the area. Roman remains have been found in the valley and it is thought that roads from York to Chester, and from settlements in Halifax and Wakefield, passed through Cleckheaton. Cleckheaton was in the ancient parish of Birstall. A chapel of ease, known as the White Chapel (later Whitechapel) was established. Textile working The area was very disorganised for a long time after the Norman Conquest and the richest ...
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Manchester Institute Of Biotechnology
The Manchester Institute of Biotechnology, formerly the Manchester Interdisciplinary Biocentre (MIB) is a research institute of the University of Manchester, England. Role The centre has been designed to enable academic communities to explore specific areas of interdisciplinary quantitative bioscience, largely through the efforts of multidisciplinary research teams. Research at MIB follows three broadly defined, interdisciplinary and complementary themes: Biological Mechanism and Catalysis, Molecular Bioengineering, and Systems biology. History Planning for the institute began late in 1998 and culminated with the official opening on 25 October 2006 of the John Garside Building. The building won "Building of the Year" from Manchester Chamber's Building and Development Committee in 2006 along with Beetham Tower, Manchester. The building has featured in several television commercials, notably Injury Lawyers 4u. The institute was renamed the Manchester Institute of Biotechnology ...
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Department Of Chemistry, University Of Manchester
The Department of Chemistry at the University of Manchester is one of the largest Departments of Chemistry in the United Kingdom, with over 600 undergraduate and more than 200 postgraduate research students. The department has comprehensive academic coverage across the chemical sciences and in all the core sub-disciplines of chemistry, with over 120 postdoctoral researchers. Current Management Board * Head of School: Prof. David Procter * Head of Education: Dr. Alan Brisdon * Undergraduate Program Director: Dr. Andrew Regan * Subject Lead (Inorganic): Prof. David Collison * Subject Lead (Organic): Dr. Andrew Regan * Subject Lead (Physical): Prof. Nick Lockyer * Head of Teaching and Scholarship: Dr. Jenny Slaughter * PASS Management Staff: Dr. Nicholas Weise * Undergraduate Admissions Tutor: Dr. Sam Hay * International Studies: Dr. Lu Shin Wong Notable faculty The department employs 34 full-time Professors and 11 Emeritus Professors including: * David Procter, Head of School, ...
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Biophysical Chemistry
Biophysical chemistry is a physical science that uses the concepts of physics and physical chemistry for the study of biological systems. The most common feature of the research in this subject is to seek explanation of the various phenomena in biological systems in terms of either the molecules that make up the system or the supra-molecular structure of these systems. Techniques Biophysical chemists employ various techniques used in physical chemistry to probe the structure of biological systems. These techniques include spectroscopic methods such as nuclear magnetic resonance (NMR) and other techniques like X-ray diffraction and cryo-electron microscopy. An example of research in biophysical chemistry includes the work for which the 2009 Nobel Prize in Chemistry was awarded. The prize was based on X-ray crystallographic studies of the ribosome that helped to unravel the physical basis of its biological function as a molecular machine that translates mRNA into polypeptides. O ...
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Enzymology
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. Almost all metabolic processes in the cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts are catalytic RNA molecules, called ribozymes. Enzymes' specificity comes from their unique three-dimensional structures. Like all catalysts, enzymes increase the reaction ra ...
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