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Ndumu Virus
Ndumu virus is an RNA virus in the genus ''Alphavirus''. It was first isolated in 1961 from culicine mosquitoes collected in northern Natal, Union of South Africa The Union of South Africa ( nl, Unie van Zuid-Afrika; af, Unie van Suid-Afrika; ) was the historical predecessor to the present-day Republic of South Africa. It came into existence on 31 May 1910 with the unification of the Cape, Natal, Trans .... References {{Virus-stub Alphaviruses ...
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RNA Virus
An RNA virus is a virusother than a retrovirusthat has ribonucleic acid (RNA) as its genetic material. The nucleic acid is usually single-stranded RNA ( ssRNA) but it may be double-stranded (dsRNA). Notable human diseases caused by RNA viruses include the common cold, influenza, SARS, MERS, Covid-19, Dengue Virus, hepatitis C, hepatitis E, West Nile fever, Ebola virus disease, rabies, polio, mumps, and measles. The International Committee on Taxonomy of Viruses (ICTV) classifies RNA viruses as those that belong to ''Group III'', ''Group IV'' or ''Group V'' of the Baltimore classification system. This category excludes ''Group VI'', viruses with RNA genetic material but which use DNA intermediates in their life cycle: these are called retroviruses, including HIV-1 and HIV-2 which cause AIDS. As of May 2020, all known RNA viruses encoding an RNA-directed RNA polymerase are believed to form a monophyletic group, known as the realm '' Riboviria''. The majority of such RNA ...
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Alphavirus
''Alphavirus'' is a genus of RNA viruses, the sole genus in the ''Togaviridae'' family. Alphaviruses belong to group IV of the Baltimore classification of viruses, with a positive-sense, single-stranded RNA genome. There are 32 alphaviruses, which infect various vertebrates such as humans, rodents, fish, birds, and larger mammals such as horses, as well as invertebrates. Alphaviruses that could infect both vertebrates and arthropods are referred dual-host alphaviruses, while insect-specific alphaviruses such as Eilat virus and Yada yada virus are restricted to their competent arthropod vector. Transmission between species and individuals occurs mainly via mosquitoes, making the alphaviruses a member of the collection of arboviruses – or arthropod-borne viruses. Alphavirus particles are enveloped, have a 70 nm diameter, tend to be spherical (although slightly pleomorphic), and have a 40 nm isometric nucleocapsid. Genome The alphaviruses are small, spherical, e ...
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Culicinae
The Culicinae are the most extensive subfamily of mosquitoes (Culicidae) and have species in every continent except Antarctica, but are highly concentrated in tropical areas. Mosquitoes are best known as parasites to many vertebrate animals and vectors for disease. They are holometabolous insects, and most species lay their eggs in stagnant water, to benefit their aquatic larval stage. Introduction The subfamily Culicinae is the largest subfamily of Culicidae, a family of Nematocera dipterans. There are 3,046 species of Culicinae mosquitoes, in 108 genera and 11 tribes. Members of the Culicinae subfamily are small flies with fore wings for flight and hind wings reduced to halteres for balance. The mosquitoes also have long, slender, legs and proboscis-style mouth parts for feeding on vertebrate blood or plant fluids. Only the females are blood feeders, requiring a high quality protein meal before they can oviposit. Because the mosquitoes are well adapted for finding hosts, the f ...
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KwaZulu-Natal
KwaZulu-Natal (, also referred to as KZN and known as "the garden province") is a province of South Africa that was created in 1994 when the Zulu bantustan of KwaZulu ("Place of the Zulu" in Zulu) and Natal Province were merged. It is located in the southeast of the country, with a long shoreline on the Indian Ocean and sharing borders with three other provinces and the countries of Mozambique, Eswatini and Lesotho. Its capital is Pietermaritzburg, and its largest city is Durban. It is the second-most populous province in South Africa, with slightly fewer residents than Gauteng. Two areas in KwaZulu-Natal have been declared UNESCO World Heritage Sites: the iSimangaliso Wetland Park and the uKhahlamba Drakensberg Park. These areas are extremely scenic as well as important to the surrounding ecosystems. During the 1830s and early 1840s, the northern part of what is now KwaZulu-Natal was established as the Zulu Kingdom while the southern part was, briefly, the Boer Natalia Repu ...
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Union Of South Africa
The Union of South Africa ( nl, Unie van Zuid-Afrika; af, Unie van Suid-Afrika; ) was the historical predecessor to the present-day Republic of South Africa. It came into existence on 31 May 1910 with the unification of the Cape, Natal, Transvaal, and Orange River colonies. It included the territories that were formerly a part of the South African Republic and the Orange Free State. Following World War I, the Union of South Africa was a signatory of the Treaty of Versailles and became one of the founding members of the League of Nations. It was conferred the administration of South West Africa (now known as Namibia) as a League of Nations mandate. It became treated in most respects as another province of the Union, but it never was formally annexed. Like Canada, Australia and New Zealand, the Union of South Africa was a self-governing dominion of the British Empire. Its full sovereignty was confirmed with the Balfour Declaration of 1926 and the Statute of Westminster 1931. ...
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