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Mustard Procedure
The Mustard procedure was developed in 1963 by Dr. William Mustard at the Hospital for Sick Children in Toronto, Ontario, Canada. Dr. Mustard, with support from the Heart and Stroke Foundation of Canada, developed an alternative and simplified technique to the Senning procedure which was used to correct a congenital heart defect that produced “ blue babies”. The technique was adopted by other surgeons and became the standard operation for d-TGA. In his autobiography, South African cardiac surgeon Christiaan Barnard claims to have been the first to perform the operation, with Mustard only following 'several years later'. Background The defect is called transposition of the great vessels, or transposition of the great arteries (TGV or TGA). Until the late 1950s, and Senning's operation, the condition was commonly fatal. The defect causes blood from the lungs to flow back to the lungs and blood from the body to flow back to the body. This occurs because the aorta and the pul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
William Mustard
William Thornton Mustard (August 8, 1914 – December 11, 1987) was a Canadian physician and cardiac surgeon. In 1949, he was one of the first to perform open-heart surgery using a mechanical heart pump and biological lung on a dog at the Banting Institute. He developed two operations named for him: the "Mustard operation" in orthopedics used to help hip use in people with polio and the " Mustard cardiovascular procedure" used to help correct heart problems in " blue babies," which has saved thousands of children worldwide. He was also the first to treat ALCAPA with a left carotid artery end to end anastamosis in 1953. Education and training Born to Thornton and Pearl (Macdonald) Mustard in Clinton, Ontario, Mustard graduated from the University of Toronto Schools. In 1937, he received a medical degree from the University of Toronto. He spent the next year on an internship at Toronto General Hospital and the following year on an internship in surgery at the Hospital for Sic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aorta
The aorta ( ) is the main and largest artery in the human body, originating from the left ventricle of the heart and extending down to the abdomen, where it splits into two smaller arteries (the common iliac arteries). The aorta distributes oxygenated blood to all parts of the body through the systemic circulation. Structure Sections In anatomical sources, the aorta is usually divided into sections. One way of classifying a part of the aorta is by anatomical compartment, where the thoracic aorta (or thoracic portion of the aorta) runs from the heart to the diaphragm. The aorta then continues downward as the abdominal aorta (or abdominal portion of the aorta) from the diaphragm to the aortic bifurcation. Another system divides the aorta with respect to its course and the direction of blood flow. In this system, the aorta starts as the ascending aorta, travels superiorly from the heart, and then makes a hairpin turn known as the aortic arch. Following the aortic arch ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Congenital Heart Disease
A congenital heart defect (CHD), also known as a congenital heart anomaly and congenital heart disease, is a defect in the structure of the heart or great vessels that is present at birth. A congenital heart defect is classed as a cardiovascular disease. Signs and symptoms depend on the specific type of defect. Symptoms can vary from none to life-threatening. When present, symptoms may include rapid breathing, bluish skin (cyanosis), poor weight gain, and feeling tired. CHD does not cause chest pain. Most congenital heart defects are not associated with other diseases. A complication of CHD is heart failure. The cause of a congenital heart defect is often unknown. Risk factors include certain infections during pregnancy such as rubella, use of certain medications or drugs such as alcohol or tobacco, parents being closely related, or poor nutritional status or obesity in the mother. Having a parent with a congenital heart defect is also a risk factor. A number of genetic condition ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Facebook
Facebook is an online social media and social networking service owned by American company Meta Platforms. Founded in 2004 by Mark Zuckerberg with fellow Harvard College students and roommates Eduardo Saverin, Andrew McCollum, Dustin Moskovitz, and Chris Hughes, its name comes from the face book directories often given to American university students. Membership was initially limited to Harvard students, gradually expanding to other North American universities and, since 2006, anyone over 13 years old. As of July 2022, Facebook claimed 2.93 billion monthly active users, and ranked third worldwide among the most visited websites as of July 2022. It was the most downloaded mobile app of the 2010s. Facebook can be accessed from devices with Internet connectivity, such as personal computers, tablets and smartphones. After registering, users can create a profile revealing information about themselves. They can post text, photos and multimedia which are shared with any ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mortality Rate
Mortality rate, or death rate, is a measure of the number of deaths (in general, or due to a specific cause) in a particular population, scaled to the size of that population, per unit of time. Mortality rate is typically expressed in units of deaths per 1,000 individuals per year; thus, a mortality rate of 9.5 (out of 1,000) in a population of 1,000 would mean 9.5 deaths per year in that entire population, or 0.95% out of the total. It is distinct from "morbidity", which is either the prevalence or incidence of a disease, and also from the incidence rate (the number of newly appearing cases of the disease per unit of time). An important specific mortality rate measure is the crude death rate, which looks at mortality from all causes in a given time interval for a given population. , for instance, the CIA estimates that the crude death rate globally will be 7.7 deaths per 1,000 people in a population per year. In a generic form, mortality rates can be seen as calculated using (d/ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jatene Procedure
Arterial switch operation (ASO) or arterial switch, is an open heart surgical procedure used to correct dextro-transposition of the great arteries (d-TGA). Its development was pioneered by Canadian cardiac surgeon William Mustard and it was named for Brazilian cardiac surgeon Adib Jatene, who was the first to use it successfully. It was the first method of d-TGA repair to be attempted, but the last to be put into regular use because of technological limitations at the time of its conception. Use of the arterial switch is historically preceded by two atrial switch methods: the Senning and Mustard procedures. The atrial switch, which was an attempt to correct the physiology of transposition, had significant shortcomings. The arterial switch sought to address them. This has emerged as an anatomically as well as physiologically appropriate solution.Marathe SP, Talwar S. Surgery for transposition of great arteries: A historical perspective. Ann Pediatr Cardiol. 2015 May-Aug;8(2):1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Baffle (medical)
A baffle is a surgically created tunnel or wall within the heart or major blood vessels used to redirect the flow of blood. They are used in some types of heart abnormalities that a child is born with known as congenital heart defects. Baffles are usually constructed, at least in part, from a person's own heart tissue, while other methods of redirecting blood using artificial material are known by the more generic term 'conduits'. Baffle does not refer to surgical techniques that redirect blood outside the heart or blood vessels such as coronary artery bypass grafting. Baffles can be made between different structures depending on the heart condition that needs to be treated. The Mustard and Senning 'atrial switch' procedures use a baffle within the atria, redirecting blood from the superior and inferior vena cava to the left ventricle and blood from the pulmonary veins to the right ventricle, to treat transposition of the great arteries. The lateral tunnel form of the Fontan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pulmonary Artery
A pulmonary artery is an artery in the pulmonary circulation that carries deoxygenated blood from the right side of the heart to the lungs. The largest pulmonary artery is the ''main pulmonary artery'' or ''pulmonary trunk'' from the heart, and the smallest ones are the arterioles, which lead to the capillaries that surround the pulmonary alveoli. Structure The pulmonary arteries are blood vessels that carry systemic venous blood from the right ventricle of the heart to the microcirculation of the lungs. Unlike in other organs where arteries supply oxygenated blood, the blood carried by the pulmonary arteries is deoxygenated, as it is venous blood returning to the heart. The main pulmonary arteries emerge from the right side of the heart, and then split into smaller arteries that progressively divide and become arterioles, eventually narrowing into the capillary microcirculation of the lungs where gas exchange occurs. Pulmonary trunk In order of blood flow, the pulmonary art ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lung
The lungs are the primary organs of the respiratory system in humans and most other animals, including some snails and a small number of fish. In mammals and most other vertebrates, two lungs are located near the backbone on either side of the heart. Their function in the respiratory system is to extract oxygen from the air and transfer it into the bloodstream, and to release carbon dioxide from the bloodstream into the atmosphere, in a process of gas exchange. Respiration is driven by different muscular systems in different species. Mammals, reptiles and birds use their different muscles to support and foster breathing. In earlier tetrapods, air was driven into the lungs by the pharyngeal muscles via buccal pumping, a mechanism still seen in amphibians. In humans, the main muscle of respiration that drives breathing is the diaphragm. The lungs also provide airflow that makes vocal sounds including human speech possible. Humans have two lungs, one on the left and on ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Hospital For Sick Children, Toronto
The Hospital for Sick Children (HSC), corporately branded as SickKids, is a major pediatric teaching hospital located on University Avenue in Toronto, Ontario, Canada. Affiliated with the Faculty of Medicine of the University of Toronto, the hospital was ranked the top pediatric hospital in the world by Newsweek in 2021. The hospital's Peter Gilgan Centre for Research and Learning is believed to be the largest pediatric research tower in the world, at . History During 1875, an eleven-room house was rented for a year by a Toronto women's bible study group, led by Elizabeth McMaster. Opened on March 1, it set up six iron cots and "declared open a hospital 'for the admission and treatment of all sick children.'" The first patient, a scalding victim named Maggie, came in on April 3. In its first year, 44 patients were admitted to the hospital in its first year of operation, and 67 others were treated in outpatient clinics. In 1876, the hospital moved to larger facilities. In 18 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transposition Of The Great Vessels
Transposition of the great vessels (TGV) is a group of congenital heart defects involving an abnormal spatial arrangement of any of the great vessels: superior and/or inferior venae cavae, pulmonary artery, pulmonary veins, and aorta. Congenital heart diseases involving only the primary arteries (pulmonary artery and aorta) belong to a sub-group called transposition of the great arteries (TGA), which is considered the most common congenital heart lesion that presents in neonates. Types Transposed vessels can present with atriovenous, ventriculoarterial and/or arteriovenous discordance. The effects may range from a slight change in blood pressure to an interruption in circulation depending on the nature and degree of the misplacement, and on which specific vessels are involved. Although "transposed" literally means "swapped", many types of TGV involve vessels that are in abnormal positions, while not actually being swapped with each other. The terms TGV and TGA are most c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Christiaan Barnard
Christiaan Neethling Barnard (8 November 1922 – 2 September 2001) was a South African cardiac surgeon who performed the world's first human-to-human heart transplant operation. On 3 December 1967, Barnard transplanted the heart of accident-victim Denise Darvall into the chest of 54-year-old Louis Washkansky, with Washkansky regaining full consciousness and being able to talk easily with his wife, before dying eighteen days later of pneumonia, largely brought on by the anti-rejection drugs that suppressed his immune system. Barnard had told Mr. and Mrs. Washkansky that the operation had an 80% chance of success, an assessment which has been criticised as misleading. Barnard's second transplant patient, Philip Blaiberg, whose operation was performed at the beginning of 1968, returned home from the hospital and lived for a year and a half. Born in Beaufort West, Cape Province, Barnard studied medicine and practised for several years in his native South Africa. As a young docto ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
