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Meaning (House)
"Meaning" is the first episode of the third season of '' House'' and the 47th episode overall. It aired on Fox on September 5, 2006. Plot House, still benefiting from his ketamine-induced coma, is seen running and pain-free, has recovered from multiple gunshot wounds, and is back at work after two months, taking on two cases simultaneously. The first is Richard, who has been paralyzed and unable to speak since brain cancer surgery eight years earlier, and who drives his wheelchair into a pool. The second is Caren, a young woman mysteriously paralyzed from the neck down after a yoga session, despite no evidence of injury to her neck or spine. Cuddy and Wilson are convinced House is creating a mystery out of Richard's case to cure his own boredom. House concludes Caren is faking the paralysis, and tries to prove it by burning her foot, causing her to move her leg in reflex. When she develops shortness of breath, House again accuses her of faking and threatens to stick a huge nee ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
House (TV Series)
''House'' (also called ''House, M.D.'') is an American medical drama television series that originally ran on the Fox network for eight seasons, from November 16, 2004, to May 21, 2012. The series' main character is Dr. Gregory House (Hugh Laurie), an unconventional, misanthropic medical genius who, despite his dependence on pain medication, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital (PPTH) in New Jersey. The series' premise originated with Paul Attanasio, while David Shore, who is credited as creator, was primarily responsible for the conception of the title character. The series' executive producers included Shore, Attanasio, Attanasio's business partner Katie Jacobs, and film director Bryan Singer. It was filmed largely in a neighborhood and business district in Los Angeles County's Westside called Century City. The show received high critical acclaim, and was consistently one of the highest rated series in the United States. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lisa Cuddy
Lisa Cuddy, M.D., is a fictional character on the Fox medical drama ''House''. She is portrayed by Lisa Edelstein. Cuddy was the Dean of Medicine of the fictional Princeton-Plainsboro Teaching Hospital in New Jersey. Cuddy quit her job after the events of season seven's finale " Moving On". Storylines Cuddy's job title in ''House'' is Dean of Medicine and Hospital Administrator. She is Jewish, and has a mother and one sister; her father is dead. She began dreaming of becoming a doctor when she was 12, graduated from medical school at age 25 as second best in her class, and became the first female and second youngest Dean of Medicine at the age of 32 (she was actually 29 but she added three years to her age in order to seem more mature to the Selection Committee). Cuddy attended the University of Michigan, where she first met Gregory House (Hugh Laurie), and with whom she shared a one-night stand. After hiring House to run the hospital's Diagnostics Department, Cuddy began setting ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
House (season 3) Episodes
A house is a single-unit residential building. It may range in complexity from a rudimentary hut to a complex structure of wood, masonry, concrete or other material, outfitted with plumbing, electrical, and heating, ventilation, and air conditioning systems.Schoenauer, Norbert (2000). ''6,000 Years of Housing'' (rev. ed.) (New York: W.W. Norton & Company). Houses use a range of different roofing systems to keep precipitation such as rain from getting into the dwelling space. Houses may have doors or locks to secure the dwelling space and protect its inhabitants and contents from burglars or other trespassers. Most conventional modern houses in Western cultures will contain one or more bedrooms and bathrooms, a kitchen or cooking area, and a living room. A house may have a separate dining room, or the eating area may be integrated into another room. Some large houses in North America have a recreation room. In traditional agriculture-oriented societies, domestic animals such as c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cortisol
Cortisol is a steroid hormone, in the glucocorticoid class of hormones. When used as a medication, it is known as hydrocortisone. It is produced in many animals, mainly by the ''zona fasciculata'' of the adrenal cortex in the adrenal gland. It is produced in other tissues in lower quantities. It is released with a diurnal cycle and its release is increased in response to stress and low blood-glucose concentration. It functions to increase blood sugar through gluconeogenesis, to suppress the immune system, and to aid in the metabolism of fat, protein, and carbohydrates. It also decreases bone formation. Many of these functions are carried out by cortisol binding to glucocorticoid or mineralocorticoid receptors inside the cell, which then bind to DNA to impact gene expression. Health effects Metabolic response Metabolism of glucose In general, cortisol stimulates gluconeogenesis (the synthesis of 'new' glucose from non-carbohydrate sources, which occurs mainly in th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Addison's Disease
Addison's disease, also known as primary adrenal insufficiency, is a rare long-term endocrine disorder characterized by inadequate production of the steroid hormones cortisol and aldosterone by the two outer layers of the cells of the adrenal glands (adrenal cortex), causing adrenal insufficiency. Symptoms generally come on slowly and insidiously and may include abdominal pain and gastrointestinal abnormalities, weakness, and weight loss. Darkening of the skin in certain areas may also occur. Under certain circumstances, an adrenal crisis may occur with low blood pressure, vomiting, lower back pain, and loss of consciousness. Mood changes may also occur. Rapid onset of symptoms indicates acute adrenal failure which is a serious and emergent condition. An adrenal crisis can be triggered by stress, such as from an injury, surgery, or infection. Addison's disease arises from problems with the adrenal gland such that not enough of the steroid hormone cortisol and possibly aldo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adrenal Gland
The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol. They are found above the kidneys. Each gland has an outer cortex which produces steroid hormones and an inner medulla. The adrenal cortex itself is divided into three main zones: the zona glomerulosa, the zona fasciculata and the zona reticularis. The adrenal cortex produces three main types of steroid hormones: mineralocorticoids, glucocorticoids, and androgens. Mineralocorticoids (such as aldosterone) produced in the zona glomerulosa help in the regulation of blood pressure and electrolyte balance. The glucocorticoids cortisol and cortisone are synthesized in the zona fasciculata; their functions include the regulation of metabolism and immune system suppression. The innermost layer of the cortex, the zona reticularis, produces androgens that are converted to fully functional sex hormones in the gonads ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Corticosteroid
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are involved in a wide range of physiological processes, including stress response, immune response, and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. Some common naturally occurring steroid hormones are cortisol (), corticosterone (), cortisone () and aldosterone (). (Note that cortisone and aldosterone are isomers.) The main corticosteroids produced by the adrenal cortex are cortisol and aldosterone. Classes * Glucocorticoids such as cortisol affect carbohydrate, fat, and protein metabolism, and have anti-inflammatory, immunosuppressive, anti-proliferative, and vasoconstrictive effects. Anti-inflammatory effects are mediated by blocking the action of inflammatory medi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scurvy
Scurvy is a disease resulting from a lack of vitamin C (ascorbic acid). Early symptoms of deficiency include weakness, feeling tired and sore arms and legs. Without treatment, decreased red blood cells, gum disease, changes to hair, and bleeding from the skin may occur. As scurvy worsens there can be poor wound healing, personality changes, and finally death from infection or bleeding. It takes at least a month of little to no vitamin C in the diet before symptoms occur. In modern times, scurvy occurs most commonly in people with mental disorders, unusual eating habits, alcoholism, and older people who live alone. Other risk factors include intestinal malabsorption and dialysis. While many animals produce their own vitamin C, humans and a few others do not. Vitamin C is required to make the building blocks for collagen. Diagnosis is typically based on physical signs, X-rays, and improvement after treatment. Treatment is with vitamin C supplements taken by mouth. Improvemen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tumor
A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists in growing abnormally, even if the original trigger is removed. This abnormal growth usually forms a mass, when it may be called a tumor. ICD-10 classifies neoplasms into four main groups: benign neoplasms, in situ neoplasms, malignant neoplasms, and neoplasms of uncertain or unknown behavior. Malignant neoplasms are also simply known as cancers and are the focus of oncology. Prior to the abnormal growth of tissue, as neoplasia, cells often undergo an abnormal pattern of growth, such as metaplasia or dysplasia. However, metaplasia or dysplasia does not always progress to neoplasia and can occur in other conditions as well. The word is from Ancient Greek 'new' and 'formation, creation'. Types A neoplasm can be benign, potentially m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
James Wilson (House)
James Evan Wilson, M.D., is a fictional character on the Fox medical drama '' House''. He is played by Robert Sean Leonard. The character first appears in the show's pilot episode when he introduces a medical case to Dr. Gregory House. Wilson is Dr. House's only true friend, and frequently provides him with consultations and aid. Wilson is the head of the Department of Oncology at Princeton- Plainsboro Teaching Hospital. During the show's run, the characters of House and Wilson have been compared to Sherlock Holmes and Dr Watson. Wilson's portrayer, Robert Sean Leonard, has stated that his character and Dr. House were originally supposed to play these roles; but Dr. House's diagnostic team has taken over Dr. Wilson's part. Leonard also read the script of the pilot episode of CBS' ''Numb3rs'' and was planning to audition. He auditioned for Wilson instead because he felt he would more enjoy playing the character that House went to for help and because he liked the '' Odd Couple' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ketamine
Ketamine is a dissociative anesthetic used medically for induction and maintenance of anesthesia. It is also used as a recreational drug. It is one of the safest anesthetics, as, in contrast with opiates, ether, and propofol, it suppresses neither respiration nor heart rate. Ketamine is also simple to administer and highly tolerable compared to drugs with similar effects which are flammable, irritating, or even explosive. Ketamine is a novel compound, derived from PCP, created in pursuit of a safer anesthetic with similar characteristics. Ketamine is also used for acute pain management. At anesthetic doses, ketamine induces a state of "dissociative anesthesia", a trance-like state providing pain relief, sedation, and amnesia. The distinguishing features of ketamine anesthesia are preserved breathing and airway reflexes, stimulated heart function with increased blood pressure, and moderate bronchodilation. At lower, sub-anesthetic doses, ketamine is a promising agent for pain ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Deran Sarafian
Deran Sarafian is an American film and television director and actor. He directed ''Death Warrant, Gunmen,'' and ''Terminal Velocity''. He has been nominated for two Primetime Emmy Awards. Life and career Sarafian is the son of film director Richard C. Sarafian, and the nephew of director, screenwriter and producer Robert Altman. He is the brother of Ani Sarafian, Tedi Sarafian, Richard Sarafian, Jr. and Damon B. Sarafian. He has two children with ex-wife, actress Laurie Fortier. In 1983 Sarafian said he had spent the previous five years "ghost directing", i.e. taking over films where the original director was unable to complete filming. These films included ''Young Warriors'' (1983). After directing a number of genre movies in Spain and Italy, Sarafian entered into the mainstream by directing the Jean-Claude Van Damme action film ''Death Warrant''. As a film director he has worked primarily in the action and thriller genres. Sarafian has directed 23 episodes of the FOX ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
