Leonor Michaelis
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Leonor Michaelis
Leonor Michaelis (16 January 1875 – 8 October 1949) was a German biochemist, physical chemist, and physician, known for his work with Maud Menten on enzyme kinetics in 1913, as well as for work on enzyme inhibition, pH and quinones. Early life and education Leonor Michaelis was born in Berlin, Germany, on 16 January 1875, and graduated from the humanistic Koellnisches Gymnasium in 1893 after passing the Abiturienten Examen. He was Jewish. It was here that Michaelis's interest in physics and chemistry was first sparked as he was encouraged by his teachers to utilize the relatively unused laboratories at his school. With concerns about the financial stability of a pure scientist, he commenced his study of medicine at Berlin University in 1893. Among his instructors were Emil du Bois-Reymond for physiology, Emil Fischer for chemistry, and Oscar Hertwig for histology and embryology. During his time at Berlin University, Michaelis worked in the lab of Oscar Hertw ...
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Berlin
Berlin ( , ) is the capital and largest city of Germany by both area and population. Its 3.7 million inhabitants make it the European Union's most populous city, according to population within city limits. One of Germany's sixteen constituent states, Berlin is surrounded by the State of Brandenburg and contiguous with Potsdam, Brandenburg's capital. Berlin's urban area, which has a population of around 4.5 million, is the second most populous urban area in Germany after the Ruhr. The Berlin-Brandenburg capital region has around 6.2 million inhabitants and is Germany's third-largest metropolitan region after the Rhine-Ruhr and Rhine-Main regions. Berlin straddles the banks of the Spree, which flows into the Havel (a tributary of the Elbe) in the western borough of Spandau. Among the city's main topographical features are the many lakes in the western and southeastern boroughs formed by the Spree, Havel and Dahme, the largest of which is Lake Müggelsee. Due to its l ...
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Hermann Emil Fischer
Hermann Emil Louis Fischer (; 9 October 1852 – 15 July 1919) was a German chemist and 1902 recipient of the Nobel Prize in Chemistry. He discovered the Fischer esterification. He also developed the Fischer projection, a symbolic way of drawing asymmetric carbon atoms. He also hypothesized lock and key mechanism of enzyme action. He never used his first given name, and was known throughout his life simply as Emil Fischer. Early years and career Fischer was born in Euskirchen, near Cologne, the son of Laurenz Fischer, a businessman, and his wife Julie Poensgen. After graduating he wished to study natural sciences, but his father compelled him to work in the family business until determining that his son was unsuitable. Fischer then attended the University of Bonn in 1871, but switched to the University of Strasbourg in 1872. He earned his doctorate in 1874 under Adolf von Baeyer with his study of phthaleins, and was appointed to a position at the university. After eight ye ...
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Baltimore
Baltimore ( , locally: or ) is the most populous city in the U.S. state of Maryland, fourth most populous city in the Mid-Atlantic, and the 30th most populous city in the United States with a population of 585,708 in 2020. Baltimore was designated an independent city by the Constitution of Maryland in 1851, and today is the most populous independent city in the United States. As of 2021, the population of the Baltimore metropolitan area was estimated to be 2,838,327, making it the 20th largest metropolitan area in the country. Baltimore is located about north northeast of Washington, D.C., making it a principal city in the Washington–Baltimore combined statistical area (CSA), the third-largest CSA in the nation, with a 2021 estimated population of 9,946,526. Prior to European colonization, the Baltimore region was used as hunting grounds by the Susquehannock Native Americans, who were primarily settled further northwest than where the city was later built. Colonist ...
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Johns Hopkins University
Johns Hopkins University (Johns Hopkins, Hopkins, or JHU) is a private university, private research university in Baltimore, Maryland. Founded in 1876, Johns Hopkins is the oldest research university in the United States and in the western hemisphere. It consistently ranks among the most prestigious universities in the United States and the world. The university was named for its first benefactor, the American entrepreneur and Quaker philanthropist Johns Hopkins. Hopkins' $7 million bequest to establish the university was the largest Philanthropy, philanthropic gift in U.S. history up to that time. Daniel Coit Gilman, who was inaugurated as :Presidents of Johns Hopkins University, Johns Hopkins's first president on February 22, 1876, led the university to revolutionize higher education in the U.S. by integrating teaching and research. In 1900, Johns Hopkins became a founding member of the American Association of Universities. The university has led all Higher education in the U ...
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Biochemistry
Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and metabolism. Over the last decades of the 20th century, biochemistry has become successful at explaining living processes through these three disciplines. Almost all areas of the life sciences are being uncovered and developed through biochemical methodology and research. Voet (2005), p. 3. Biochemistry focuses on understanding the chemical basis which allows biological molecules to give rise to the processes that occur within living cells and between cells,Karp (2009), p. 2. in turn relating greatly to the understanding of tissues and organs, as well as organism structure and function.Miller (2012). p. 62. Biochemistry is closely related to molecular biology, which is the study of the molecular mechanisms of biological phenomena.As ...
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Nagoya University
, abbreviated to or NU, is a Japanese national research university located in Chikusa-ku, Nagoya. It was the seventh Imperial University in Japan, one of the first five Designated National University and selected as a Top Type university of Top Global University Project by the Japanese government. It is the 3rd highest ranked higher education institution in Japan (84th worldwide). The university is the birthplace of the Sakata School of physics and the Hirata School of chemistry. As of 2021, seven Nobel Prize winners have been associated with Nagoya University, the third most in Japan and Asia behind Kyoto University and the University of Tokyo. History Nagoya University traces its roots back to 1871 when it was the Temporary Medical School/Public Hospital. In 1939 it became Nagoya Imperial University (), the last Imperial University of Japanese Empire. In 1947 it was renamed Nagoya University (), and became a Japanese national university. In 2014, according to the r ...
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Emil Abderhalden
Emil Abderhalden (9 March 1877 – 5 August 1950) was a Swiss biochemist and physiologist. His main findings, though disputed already in the 1910s, were not finally rejected until the late 1990s. Whether his misleading findings were based on fraud or simply the result of a lack of scientific rigor remains unclear. Abderhalden's drying pistol, used in chemistry, was first described by one of his students in a textbook Abderhalden edited. Biography Emil Abderhalden was born in Oberuzwil in the Canton of St. Gallen in Switzerland. He moved to Basel to study at the University of Basel. During his time in Basel, he joined the rowing club and was founder member of FC Basel. Eleven men attended the meeting of founding Fussball Club Basel on 15 November 1893. Abderhalden played his first game for the club in the home game in the Stadion Schützenmatte on 22 September 1894 as Basel won 2–0 against FC Gymnasia. Abderhalden left the club in January 1895. Abderhalden studied medicine a ...
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Ernst Viktor Von Leyden
Ernst Viktor von Leyden (20 April 1832 – 5 October 1910) was a German internist from Danzig. Biography He studied medicine at the Friedrich-Wilhelms-Institut in Berlin, and was a pupil of Johann Lukas Schönlein (1793–1864) and Ludwig Traube (1818–1876). He was later a medical professor at the universities of Königsberg, Strassburg and Berlin. Leyden was an important influence to the career of Ludwig Edinger (1855–1918), and during his tenure at the University of Königsberg worked closely with Otto Spiegelberg (1830–1881) and Friedrich Daniel von Recklinghausen (1833–1910).''Ernst Viktor von Leyden''
at Who Named It
Among his better known students and assistants were
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Moritz Litten
Moritz Litten (August 10, 1845 – May 31, 1907) was a German physician who was a native of Berlin. He was a son-in-law to pathologist Ludwig Traube (1818–1876). Biography He studied medicine at the Universities of Heidelberg, Marburg and Berlin, earning his medical doctorate in 1868. From 1872 to 1876 he worked at the Allerheiligen Hospital in Breslau, and in the meantime, served as an assistant to Julius Friedrich Cohnheim (1839–1884). From 1876 to 1882 he worked in the clinic of Friedrich Theodor von Frerichs at Berlin-Charité. In 1884 he obtained the title of professor. Litten is remembered for being the first physician to describe vitreous bleeding in correlation with subarachnoid hemorrhage (SAH). In 1881 he published his findings in ''Ueber einige vom allgemein-klinischen Standpunkt aus interessante Augenveränderungen'' (Berl Klin Wochenschr 18: 23– 27). Several years later, French ophthalmologist Albert Terson noticed these symptoms in a patient, and the c ...
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Freiburg
Freiburg im Breisgau (; abbreviated as Freiburg i. Br. or Freiburg i. B.; Low Alemannic: ''Friburg im Brisgau''), commonly referred to as Freiburg, is an independent city in Baden-Württemberg, Germany. With a population of about 230,000 (as of 31 December 2018), Freiburg is the fourth-largest city in Baden-Württemberg after Stuttgart, Mannheim, and Karlsruhe. The population of the Freiburg metropolitan area was 656,753 in 2018. In the south-west of the country, it straddles the Dreisam river, at the foot of the Schlossberg. Historically, the city has acted as the hub of the Breisgau region on the western edge of the Black Forest in the Upper Rhine Plain. A famous old German university town, and archiepiscopal seat, Freiburg was incorporated in the early twelfth century and developed into a major commercial, intellectual, and ecclesiastical center of the upper Rhine region. The city is known for its medieval minster and Renaissance university, as well as for its high stand ...
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Cytopathology
Cytopathology (from Greek , ''kytos'', "a hollow"; , ''pathos'', "fate, harm"; and , '' -logia'') is a branch of pathology that studies and diagnoses diseases on the cellular level. The discipline was founded by George Nicolas Papanicolaou in 1928. Cytopathology is generally used on samples of free cells or tissue fragments, in contrast to histopathology, which studies whole tissues. Cytopathology is frequently, less precisely, called "cytology", which means "the study of cells". Cytopathology is commonly used to investigate diseases involving a wide range of body sites, often to aid in the diagnosis of cancer but also in the diagnosis of some infectious diseases and other inflammatory conditions. For example, a common application of cytopathology is the Pap smear, a screening tool used to detect precancerous cervical lesions that may lead to cervical cancer. Cytopathologic tests are sometimes called smear tests because the samples may be smeared across a glass microscope slid ...
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Embryology
Embryology (from Greek ἔμβρυον, ''embryon'', "the unborn, embryo"; and -λογία, '' -logia'') is the branch of animal biology that studies the prenatal development of gametes (sex cells), fertilization, and development of embryos and fetuses. Additionally, embryology encompasses the study of congenital disorders that occur before birth, known as teratology. Early embryology was proposed by Marcello Malpighi, and known as preformationism, the theory that organisms develop from pre-existing miniature versions of themselves. Aristotle proposed the theory that is now accepted, epigenesis. Epigenesis is the idea that organisms develop from seed or egg in a sequence of steps. Modern embryology, developed from the work of Karl Ernst von Baer, though accurate observations had been made in Italy by anatomists such as Aldrovandi and Leonardo da Vinci in the Renaissance. Comparative embryology Preformationism and epigenesis As recently as the 18th century, the prevailin ...
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