Leon Eisenberg
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Leon Eisenberg
Leon Eisenberg (August 8, 1922 – September 15, 2009) was an American child psychiatrist, social psychiatrist and medical educator who "transformed child psychiatry by advocating research into developmental problems". He is credited with a number of "firsts" in medicine and psychiatry – in child psychiatry, autism, and the controversies around autism, randomized clinical trials (RCTs), social medicine, global health, affirmative action, and evidence-based psychiatry. He served as Chair of the Johns Hopkins Hospital Department of Child and adolescent psychiatry and Harvard Medical School until1988, when he retired. After retirement, he continued as The Maude and Lillian Presley Professor of Social Medicine, Psychiatry Emeritus, and in the Department of Global Health and Social Medicine of the Harvard Medical School in the Longwood Medical Area of Boston, until a few months before his death in 2009. He received both his BA and MD degrees from the Perelman School of Medicine a ...
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Philadelphia
Philadelphia, often called Philly, is the largest city in the Commonwealth of Pennsylvania, the sixth-largest city in the U.S., the second-largest city in both the Northeast megalopolis and Mid-Atlantic regions after New York City. Since 1854, the city has been coextensive with Philadelphia County, the most populous county in Pennsylvania and the urban core of the Delaware Valley, the nation's seventh-largest and one of world's largest metropolitan regions, with 6.245 million residents . The city's population at the 2020 census was 1,603,797, and over 56 million people live within of Philadelphia. Philadelphia was founded in 1682 by William Penn, an English Quaker. The city served as capital of the Pennsylvania Colony during the British colonial era and went on to play a historic and vital role as the central meeting place for the nation's founding fathers whose plans and actions in Philadelphia ultimately inspired the American Revolution and the nation's inde ...
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Longwood Medical And Academic Area
The Longwood Medical and Academic Area (also known as Longwood Medical Area, LMA, or simply Longwood) is a medical campus in Boston, Massachusetts. Flanking Longwood Avenue, LMA is adjacent to the Fenway–Kenmore, Audubon Circle, and Mission Hill neighborhoods, as well as the town of Brookline. It is most strongly associated with Harvard Medical School, the Harvard T.H. Chan School of Public Health, the Harvard School of Dental Medicine, and other medical facilities such as Harvard's teaching hospitals, but prominent non-Harvard institutions are located there as well. Long known as a global center of research, institutions in the Longwood Medical Area secured over $1.2 billion in NIH funds alone, in FY 2018 which exceeds funding received by 44 states. Hospitals and research institutions * Beth Israel Deaconess Medical Center * Boston Children's Hospital * Brigham and Women's Hospital * Dana–Farber Cancer Institute * Joslin Diabetes Center * Massachusetts Mental Health Cente ...
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Anxiety Disorders
Anxiety disorders are a cluster of mental disorders characterized by significant and uncontrollable feelings of anxiety and fear such that a person's social, occupational, and personal function are significantly impaired. Anxiety may cause physical and cognitive symptoms, such as restlessness, irritability, easy fatiguability, difficulty concentrating, increased heart rate, chest pain, abdominal pain, and a variety of other symptoms that may vary based on the individual. In casual discourse, the words ''anxiety'' and ''fear'' are often used interchangeably. In clinical usage, they have distinct meanings: anxiety is defined as an unpleasant emotional state for which the cause is either not readily identified or perceived to be uncontrollable or unavoidable, whereas fear is an emotional and physiological response to a recognized external threat. The umbrella term ''anxiety disorder'' refers to a number of specific disorders that include fears (phobias) or anxiety symptoms. There a ...
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Psychopharmacology
Psychopharmacology (from Greek grc, ψῡχή, psȳkhē, breath, life, soul, label=none; grc, φάρμακον, pharmakon, drug, label=none; and grc, -λογία, -logia, label=none) is the scientific study of the effects drugs have on mood, sensation, thinking, behavior, judgment and evaluation, and memory. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior. The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain. The term "psychopharmacology" was likely first coined by David Macht in 1920. Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and ...
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Randomized Controlled Trial
A randomized controlled trial (or randomized control trial; RCT) is a form of scientific experiment used to control factors not under direct experimental control. Examples of RCTs are clinical trials that compare the effects of drugs, surgical techniques, medical devices, diagnostic procedures or other medical treatments. Participants who enroll in RCTs differ from one another in known and unknown ways that can influence study outcomes, and yet cannot be directly controlled. By Random assignment, randomly allocating participants among compared treatments, an RCT enables ''statistical control'' over these influences. Provided it is designed well, conducted properly, and enrolls enough participants, an RCT may achieve sufficient control over these confounding factors to deliver a useful comparison of the treatments studied. Definition and examples An RCT in clinical research typically compares a proposed new treatment against an existing Standard of care#Medical standard of care, ...
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Evidence-based
Evidence-based practice (EBP) is the idea that occupational practices ought to be based on scientific evidence. While seemingly obviously desirable, the proposal has been controversial, with some arguing that results may not specialize to individuals as well as traditional practices. Evidence-based practices have been gaining ground since the formal introduction of evidence-based medicine in 1992 and have spread to the allied health professions, education, management, law, public policy, architecture, and other fields. In light of studies showing problems in scientific research (such as the replication crisis), there is also a movement to apply evidence-based practices in scientific research itself. Research into the evidence-based practice of science is called metascience. The movement towards evidence-based practices attempts to encourage and, in some instances, require professionals and other decision-makers to pay more attention to evidence to inform their decision-making. Th ...
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Phobia
A phobia is an anxiety disorder defined by a persistent and excessive fear of an object or situation. Phobias typically result in a rapid onset of fear and are usually present for more than six months. Those affected go to great lengths to avoid the situation or object, to a degree greater than the actual danger posed. If the object or situation cannot be avoided, they experience significant distress. Other symptoms can include fainting, which may occur in blood or injury phobia, and panic attacks, often found in agoraphobia. Around 75% of those with phobias have multiple phobias. Phobias can be divided into specific phobias, social anxiety disorder, and agoraphobia. Specific phobias are further divided to include certain animals, natural environment, blood or injury, and particular situations. The most common are fear of spiders, fear of snakes, and fear of heights. Specific phobias may be caused by a negative experience with the object or situation in early childhood. Soci ...
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Separation Anxiety Disorder
Separation anxiety disorder (SAD) is an anxiety disorder in which an individual experiences excessive anxiety regarding separation from home and/or from people to whom the individual has a strong emotional attachment (e.g., a parent, caregiver, significant other, or siblings). Separation anxiety is a natural part of the developmental process. It is most common in infants and little children, typically between the ages of six to seven months to three years, although it may pathologically manifest itself in older children, adolescents and adults. Unlike SAD (indicated by excessive anxiety), normal separation anxiety indicates healthy advancements in a child's cognitive maturation and should not be considered a developing behavioral problem. According to the American Psychiatric Association (APA), separation anxiety disorder is an excessive display of fear and distress when faced with situations of separation from the home and/or from a specific attachment figure. The anxiety that ...
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Michael Rutter
Sir Michael Llewellyn Rutter CBE FRS FRCP FRCPsych FMedSci (15 August 1933 – 23 October 2021) was the first person to be appointed professor of child psychiatry in the United Kingdom. He has been described as the "father of child psychology". Rutter was professor of developmental psychopathology at the Institute of Psychiatry, King's College London and consultant psychiatrist at the Maudsley Hospital, a post he held since 1966, until retiring in July 2021. A ''Review of General Psychology'' survey, published in 2002, ranked Rutter as the 68th most cited psychologist of the 20th century. He died of cancer on October 23, 2021, aged 88. Early life Rutter was the oldest child born to Winifred (née Barber) and Llewellyn Rutter. He was born in Lebanon where his father was a doctor, and was bilingual in English and Arabic by the age of 3. The family moved back to England when he was 4 years old. In 1940, at the age of 7, Rutter was evacuated, with his younger sister, to North ...
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American Journal Of Psychiatry
''The American Journal of Psychiatry'' is a monthly peer-reviewed medical journal covering all aspects of psychiatry, and is the official journal of the American Psychiatric Association. The first volume was issued in 1844, at which time it was known as the ''American Journal of Insanity''. The title changed to the current form with the July issue of 1921. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor of 18.112. Ethical concerns Several complaints, including legal cases, have charged ''The American Journal of Psychiatry'' with being complicit in pharmaceutical industry corruption of clinical trial results. In a Department of Justice case against Forest Pharmaceuticals, Forest pleaded guilty to the charges of misbranding the drug Celexa (citalopram). The Complaint in Intervention clearly identifies a 2004 ghostwritten article published in ‘’The American Journal of Psychiatry'' in the names of Wagner ''et al.'' as a part of this illegal ma ...
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Massachusetts General Hospital
Massachusetts General Hospital (Mass General or MGH) is the original and largest teaching hospital of Harvard Medical School located in the West End neighborhood of Boston, Massachusetts. It is the third oldest general hospital in the United States and has a capacity of 999 beds. With Brigham and Women's Hospital, it is one of the two founding members of Mass General Brigham (formerly known as Partners HealthCare), the largest healthcare provider in Massachusetts. Massachusetts General Hospital houses the largest hospital-based research program in the world, the Mass General Research Institute, with an annual research budget of more than $1 billion in 2019. It is currently ranked as the #8 best hospital in the United States by '' U.S. News & World Report''. In , ''The Boston Globe'' ranked MGH the fifth best place to work out of Massachusetts companies with over 1,000 employees. History Founded in 1811, the original hospital was designed by the famous American architect Char ...
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Baltimore
Baltimore ( , locally: or ) is the most populous city in the U.S. state of Maryland, fourth most populous city in the Mid-Atlantic, and the 30th most populous city in the United States with a population of 585,708 in 2020. Baltimore was designated an independent city by the Constitution of Maryland in 1851, and today is the most populous independent city in the United States. As of 2021, the population of the Baltimore metropolitan area was estimated to be 2,838,327, making it the 20th largest metropolitan area in the country. Baltimore is located about north northeast of Washington, D.C., making it a principal city in the Washington–Baltimore combined statistical area (CSA), the third-largest CSA in the nation, with a 2021 estimated population of 9,946,526. Prior to European colonization, the Baltimore region was used as hunting grounds by the Susquehannock Native Americans, who were primarily settled further northwest than where the city was later built. Colonist ...
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