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List Of Investigational Drugs
These are lists of investigational drugs: * List of investigational analgesics * List of investigational antidepressants * List of investigational antipsychotics * List of investigational anxiolytics * List of investigational attention deficit hyperactivity disorder drugs * List of investigational hallucinogens and entactogens * List of investigational obsessive–compulsive disorder drugs * List of investigational sex-hormonal agents * List of investigational sexual dysfunction drugs * List of investigational sleep drugs This is a list of investigational sleep drugs, or drugs for the treatment of sleep disorders that are currently under development for clinical use but are not yet approved. ''Chemical/generic names are listed first, with developmental code names, s ... {{DEFAULTSORT:Investigational drugs Drug-related lists Experimental drugs ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Investigational Analgesics
This is a list of investigational analgesics, or analgesics that are currently under development for clinical use but are not yet approved. ''Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses.'' Opioid receptor modulators * Axelopran/oxycodone – combination of a centrally active μ-opioid receptor agonist and a peripherally selective μ-, κ-opioid receptor, κ-, and δ-opioid receptor receptor antagonist, antagonist. * Cebranopadol (GRT-6005) – non-selective μ-opioid receptor, nociceptin receptor, and δ-opioid receptor full agonist and κ-opioid receptor partial agonist * Desmetramadol (''O''-desmethyltramadol; Omnitram) – μ-opioid receptor agonist, norepinephrine reuptake inhibitor (NRI), and 5-HT2C receptor, 5-HT2C receptor antagonist. * Lexanopadol (GRT-6006, GRT13106G) – non-selective opioid receptor agonist * Oxycodone/naltrexone – combination of a μ-opioid receptor agonist and a μ- and κ-opioid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Investigational Antidepressants
This is a list of investigational antidepressants, or antidepressants that are currently under development for clinical use in the treatment of mood disorders but are not yet approved. ''Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses.'' All drugs listed are specifically under development for major depressive disorder (MDD) and/or treatment-resistant depression (TRD) unless noted otherwise. Other forms of depression may include bipolar depression and postpartum depression. Glutamatergics NMDA receptor modulators * 4-Chlorokynurenine (AV-101) – NMDA receptor glycine site antagonist * Apimostinel (GATE-202, NRX-1074) – NMDA receptor modulator * Arketamine (PCN-101, HR-071603) – unknown mechanism of action, indirect AMPA receptor activator * Esketamine (Esketamine DPI, Falkieri, PG061) – non-competitive NMDA receptor antagonist – approved for TRD, specifically under development for bipolar depression an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Investigational Antipsychotics
This is a list of investigational antipsychotics, or antipsychotics that are currently under development for clinical use but are not yet approved. ''Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses.'' Receptor modulators Monoamine receptor modulators * ATI-9242 – atypical antipsychotic ( D2 and 5-HT2A receptor antagonist, other actions) * AVN-211 (CD-008-0173) – 5-HT6 receptor antagonist * Brilaroxazine (RP-5063, RP-5000; oxaripiprazole) – atypical antipsychotic (D2 receptor partial agonist, 5-HT2A receptor antagonist, other actions) * F-17464 – D3 receptor antagonist, 5-HT1A receptor partial agonist, and weak D2 receptor partial agonist * FKF-02SC (TGOF-02N) – atypical antipsychotic (D2 and 5-HT2A receptor antagonist, other actions) * LB-102 – D2,3, 5-HT7, receptor antagonists (methylated version of amisulpride) * Lu-AF35700 – D1, 5-HT2A, and 5-HT6 receptor antagonist * Masupirdine (SUVN- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Investigational Anxiolytics
This is a list of investigational anxiolytics, or anxiolytics that are currently under development for clinical use but are not yet approved. Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses. Generalized anxiety disorder * Agomelatine (AGO-178; Valdoxan) – melatonin MT1 and MT2 receptor agonist, 5-HT2C receptor antagonist* Riluzole sublingual (BHV-0223) – undefined mechanism of action * TGFK08AA – 5-HT ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Investigational Attention Deficit Hyperactivity Disorder Drugs
This is a list of investigational attention deficit hyperactivity disorder drugs, or drugs that are currently under development for clinical use in the treatment of attention deficit hyperactivity disorder (ADHD) but are not yet approved. ''Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses.'' Under development Preregistration * TRN-110 xtended-release- undefined mechanism / extended-release form of an undisclosed dru Phase 3 clinical trials * Centanafadine ustained-release(centanafadine SR, CTN-SR, EB-1020, EB-1020 SR) - serotonin–norepinephrine–dopamine reuptake inhibito* Molindone xtended-release(AFX-2201, EN-1733A, molindone XR, SPN-810, SPN-810M, Zalvari) - antipsychotic / dopamine D2 receptor antagonist and serotonin receptor modulator (e.g., serotonin 5-HT2B and 5-HT2A receptor antagonist) - specifically under development for impulsive aggression in ADHref name="pmid32338106"> * Serdexmethylphenidate ( ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Investigational Hallucinogens And Entactogens
This is a list of investigational hallucinogens and entactogens, or hallucinogens and entactogens that are currently under formal development for clinical use but are not yet approved. Many of the indications are not for continuous medication therapy but rather for medication-assisted psychotherapy or short-term use only. ''Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses.'' Hallucinogens Psychedelics * Dimethyltryptamine (DMT) – addiction, substance-related disorders – Entheon Biomedica* Lysergic acid diethylamide (LSD; "Lucy") – anxiety disorders, attention-deficit hyperactivity disorder – MAPS, MindMedbr> ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Investigational Obsessive–compulsive Disorder Drugs
This is a list of investigational obsessive–compulsive disorder drugs, or drugs that are currently under development for clinical use in the treatment of obsessive–compulsive disorder (OCD) but are not yet approved. Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses. Under development Actively under development * Immunoglobulin (immune globulin 10%, 10% high purity immunoglobulin, 10% IVIG, NewGam, Newnorm, Octagam 10%, Octagam, Panzyga) – immunoglobulin / immunostimulanref name="pmid33447096" /> * Troriluzole (BHV-4157, BHV-4157a, FC-4157; trigriluzole) – prodrug of riluzole / glutamate modulatoref name="pmid33447096" /> Preclinical development * Cannabis extracts (various) – cannabinoid receptor modulator No development reported * 4'-Fluorocannabidiol (4'-F-CBD; fluorinated cannabidiol; HUF-101, HUF-102, HUF-103) – cannabinoid receptor modulator, other action* AbbVie/Rugen research programme – unspec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Investigational Sex-hormonal Agents
This is a list of investigational sex-hormonal agents, or sex-hormonal agents that are currently under development for clinical use but are not yet approved. ''Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses.'' Androgenics Androgen receptor agonists * EC586 – oral administration, oral prodrug of testosterone (medication), testosterone (androgen/anabolic steroid) with improved pharmacokinetics Androgen receptor antagonists * Bavdegalutamide (AVR-110) – androgen receptor antagonist for prostate cancerref name="pmid33160761"> * Clascoterone (CB-03-01, Breezula, Winlevi) – androgen receptor antagonist for topical medication, topical treatment of scalp hair loss] [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Investigational Sexual Dysfunction Drugs
This is a list of investigational sexual dysfunction drugs, or drugs that are currently under development for clinical treatment of sexual dysfunction but are not yet approved. ''Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses.'' Atrophic vaginitis * Estetrol (E4; Donesta) – estrogen receptor agonisEstetrol - Mithra Pharmaceuticals - AdisInsight* Lasofoxifene (CP-336156, CP-336156-CB, Fablyn, Oporia) – selective estrogen receptor modulatorLasofoxifene - Sermonix Pharmaceuticals - AdisInsight Erectile dysfunction * HCP-1302 – undefined mechanism of actionHCP 1302 - AdisInsight* [ itroglycerin gel (Eroxon, Futura, MED-2001–MED-2005) – NO donor, nitric oxide donorNitroglycerin gel - Futura Medical - AdisInsight* Tadalafil/tamsulosin (HCP-1303, CKD-397, YBH-160Tadalafil/tamsulosin - Hanmi Pharmaceutical - AdisInsighthttp://adisinsight.springer.com/drugs/800047508 Tadalafil/tamsulosin - Ildong Pharmaceutical - ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Investigational Sleep Drugs
This is a list of investigational sleep drugs, or drugs for the treatment of sleep disorders that are currently under development for clinical use but are not yet approved. ''Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses.'' Insomnia GABAA receptor potentiators * EVT-201 – GABAA receptor, GABAA receptor positive allosteric modulator* Lorediplon (GF-015535-00) – GABAA receptor positive allosteric modulato * Zuranolone (SAGE-217) – GABAA receptor positive allosteric modulato Orexin receptor antagonists * Seltorexant (MIN-202, JNJ,42847922, JNJ-922) – selective OX2 receptor antagonis* Vornorexant (ORN-0829, TS-142) – dual OX1 and OX2 receptor antagonis Melatonin receptor agonists * Piromelatine (Neu-P11) – melatonin receptor agonist and 5-HT1A receptor, 5-HT1A and 5-HT1D receptor, 5-HT1D receptor agonis Nociceptin receptor agonists * Sunobinop (IMB-115, IT-1315, S-117957, V-117957) – nociceptin receptor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |