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Lathyrism
Lathyrism is a condition caused by eating certain legumes of the genus ''Lathyrus''. There are three types of lathyrism: ''neurolathyrism'', ''osteolathyrism'', and ''angiolathyrism'', all of which are incurable, differing in their symptoms and in the body tissues affected. Neurolathyrism is the type associated with the consumption of legumes in the genus ''Lathyrus'' that contain the toxin ODAP. ODAP ingestion results in motorneuron death. The result is paralysis and muscle atrophy of the lower limbs. Osteolathyrism, a different type of lathyrism, affects the connective tissues, not the motorneurons. Osteolathyrism results from the ingestion of ''Lathyrus odoratus'' seeds (sweet peas), and is often referred to as odoratism. It is caused by a different toxin, beta-aminopropionitrile, which affects the linking of the subunits of collagen, a major structural protein found in connective tissue. A third type of lathyrism is angiolathyrism, which is similar to osteolathyrism in its ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurolathyrism
Neurolathyrism, is a neurological disease of humans, caused by eating certain legumes of the genus ''Lathyrus''. This disease is mainly associated with the consumption of ''Lathyrus sativus'' (also known as ''grass pea'', ''chickling pea'', ''kesari dal'', or ''almorta'') and to a lesser degree with ''Lathyrus cicera'', ''Lathyrus ochrus'' and ''Lathyrus clymenum'' containing the toxin ODAP. This is not to be confused with osteolathyrism, a different type of lathyrism that affects the connective tissues. Osteolathyrism results from the ingestion of ''Lathyrus odoratus'' seeds (''sweet peas'') and is often referred to as odoratism. It is caused by a different toxin (beta-aminopropionitrile) which affects the linking of collagen, a protein of connective tissues. Another type of lathyrism is angiolathyrism which is similar to osteolathyrism in its effects on connective tissue. However, the blood vessels are affected as opposed to bone. Signs and symptoms The consumption of large qu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurolathyrism
Neurolathyrism, is a neurological disease of humans, caused by eating certain legumes of the genus ''Lathyrus''. This disease is mainly associated with the consumption of ''Lathyrus sativus'' (also known as ''grass pea'', ''chickling pea'', ''kesari dal'', or ''almorta'') and to a lesser degree with ''Lathyrus cicera'', ''Lathyrus ochrus'' and ''Lathyrus clymenum'' containing the toxin ODAP. This is not to be confused with osteolathyrism, a different type of lathyrism that affects the connective tissues. Osteolathyrism results from the ingestion of ''Lathyrus odoratus'' seeds (''sweet peas'') and is often referred to as odoratism. It is caused by a different toxin (beta-aminopropionitrile) which affects the linking of collagen, a protein of connective tissues. Another type of lathyrism is angiolathyrism which is similar to osteolathyrism in its effects on connective tissue. However, the blood vessels are affected as opposed to bone. Signs and symptoms The consumption of large qu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Angiolathyrism
Angiolathyrism is a form of Lathyrism disease. It is mainly caused the consumption of ''Lathyrus sativus'' (also known as ''grass pea'') and to a lesser degree by ''Lathyrus cicera'', ''Lathyrus ochrus'' and ''Lathyrus clymenum'' at ''Prince Leopold Institute of Tropical Medicine'' online database containing the . The main chemical responsible is β- |
Angiolathyrism
Angiolathyrism is a form of Lathyrism disease. It is mainly caused the consumption of ''Lathyrus sativus'' (also known as ''grass pea'') and to a lesser degree by ''Lathyrus cicera'', ''Lathyrus ochrus'' and ''Lathyrus clymenum'' at ''Prince Leopold Institute of Tropical Medicine'' online database containing the . The main chemical responsible is β- |
Osteolathyrism
Osteolathyrism, sometimes referred to as odoratism, is a form of the disease Lathyrism. The disease results from the ingestion of ''Lathyrus odoratus'' seeds (sweet peas). The toxin found in the sweet peas is (beta-aminopropionitrile), which affects the linking of collagen, a protein of connective tissues. The condition results in damage to bone and mesenchymal connective tissues. Osteolathyrism occurs in people in combination with neurolathyrism and angiolathyrism in areas where famine demands reliance on a crop with known detrimental effects. It occurs in cattle and horses with diets overreliant upon the grass pea. Prominent symptoms include skeletal deformities and bone pain. Signs and symptoms *Bone pain *Skeletal deformity *Fatigue *Malnourishment Cause Aside from ''L. odoratus'', other members of the genus are also known to cause the disease, including '' L. sylvestris'', '' L. cicera'', and '' L. clymenum''. ''L. odoratus'' grows well under famine conditions, often se ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Osteolathyrism
Osteolathyrism, sometimes referred to as odoratism, is a form of the disease Lathyrism. The disease results from the ingestion of ''Lathyrus odoratus'' seeds (sweet peas). The toxin found in the sweet peas is (beta-aminopropionitrile), which affects the linking of collagen, a protein of connective tissues. The condition results in damage to bone and mesenchymal connective tissues. Osteolathyrism occurs in people in combination with neurolathyrism and angiolathyrism in areas where famine demands reliance on a crop with known detrimental effects. It occurs in cattle and horses with diets overreliant upon the grass pea. Prominent symptoms include skeletal deformities and bone pain. Signs and symptoms *Bone pain *Skeletal deformity *Fatigue *Malnourishment Cause Aside from ''L. odoratus'', other members of the genus are also known to cause the disease, including '' L. sylvestris'', '' L. cicera'', and '' L. clymenum''. ''L. odoratus'' grows well under famine conditions, often se ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lathyrus
''Lathyrus'' is a genus of flowering plants in the legume family Fabaceae, and contains approximately 160 species. Commonly known as peavines or vetchlings, they are native to temperate areas, with a breakdown of 52 species in Europe, 30 species in North America, 78 in Asia, 24 in tropical East Africa, and 24 in temperate South America. There are annual and perennial species which may be climbing or bushy. This genus has numerous sections, including ''Orobus'', which was once a separate genus. Uses Many species are cultivated as garden plants. The genus includes the garden sweet pea (''Lathyrus odoratus'') and the perennial everlasting pea (''Lathyrus latifolius''). Flowers on these cultivated species may be rose, red, maroon, pink, white, yellow, purple or blue, and some are bicolored. They are also grown for their fragrance. Cultivated species are susceptible to fungal infections including downy and powdery mildew. Other species are grown for food, including the Indian pea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lathyrus Sativus
''Lathyrus sativus'', also known as grass pea, cicerchia, blue sweet pea, chickling pea, chickling vetch, Indian pea, white pea and white vetch,''Kew Gardens'''Lathyrus sativus'' (grass pea) is a legume (family Fabaceae) commonly grown for human consumption and livestock feed in Asia and East Africa. It is a particularly important crop in areas that are prone to drought and famine, and is thought of as an 'insurance crop' as it produces reliable yields when all other crops fail. The Serra de'Conti Cicerchia is included in the Ark of Taste. The seeds contain a neurotoxin that causes lathyrism, a neurodegenerative disease, if eaten as a primary protein source for a prolonged period. Cultivation ''Lathyrus sativus'' grows best where the average temperature is 10–25 °C and average rainfall is per year. Like other legumes, it improves the nitrogen content of soil. The crop can survive drought or floods, but grows best in moist soils. It tolerates a range of soil types from l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lathyrus Odoratus
The sweet pea, ''Lathyrus odoratus'', is a flowering plant in the genus ''Lathyrus'' in the family Fabaceae (legumes), native to Sicily, southern Italy and the Aegean Islands. It is an annual climbing plant, growing to a height of , where suitable support is available. The leaves are pinnate with two leaflets and a terminal tendril, which twines around supporting plants and structures, helping the sweet pea to climb. In the wild plant the flowers are purple, broad; they are larger and highly variable in color in the many cultivars. Flowers are usually strongly scented. The annual species, ''L. odoratus'', may be confused with the everlasting pea, '' L. latifolius'', a perennial. Horticultural development Scottish nurseryman Henry Eckford (1823–1905) cross-bred and developed the sweet pea, turning it from a rather insignificant if sweetly scented flower into a floral sensation of the 19th century. His initial success and recognition came while serving as head gardener for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Beta-aminopropionitrile
Aminopropionitrile, also known as β-aminopropionitrile (BAPN), is an organic compound with both amine and nitrile functional groups. It is a colourless liquid. The compound occurs naturally and is of interest in the biomedical community. Biochemical and medical occurrence BAPN is the toxic constituent of peas from Lathyrus plants, e.g., lathyrus odoratus. Lathyrism, a disease known for centuries, encompasses 2 distinct entities: a disorder of the nervous system (neurolathyrism) leading to limb paralysis, and a disorder of connective tissue, causing either bone deformity (osteolathyrism) or aortic aneurisms (angiolathyrim). BAPN causes osteolathyrism and angiolathyrism when ingested in large quantities." It can cause osteolathyrism, neurolathyrism, and/or angiolathyrism. It is an antirheumatic agent in veterinary medicine. It has attracted interest as an anticancer agent. Production Aminopropionitrile is prepared by the reaction of ammonia with acrylonitrile.Karsten Eller, Erhar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amino Acid
Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although hundreds of amino acids exist in nature, by far the most important are the alpha-amino acids, which comprise proteins. Only 22 alpha amino acids appear in the genetic code. Amino acids can be classified according to the locations of the core structural functional groups, as Alpha and beta carbon, alpha- , beta- , gamma- or delta- amino acids; other categories relate to Chemical polarity, polarity, ionization, and side chain group type (aliphatic, Open-chain compound, acyclic, aromatic, containing hydroxyl or sulfur, etc.). In the form of proteins, amino acid '' residues'' form the second-largest component (water being the largest) of human muscles and other tissues. Beyond their role as residues in proteins, amino acids participate in a number of processes such as neurotransmitter transport and biosynthesis. It is thought that they played a key role in enabling life ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hippocrates
Hippocrates of Kos (; grc-gre, Ἱπποκράτης ὁ Κῷος, Hippokrátēs ho Kôios; ), also known as Hippocrates II, was a Greek physician of the classical period who is considered one of the most outstanding figures in the history of medicine. He is traditionally referred to as the "Father of Medicine" in recognition of his lasting contributions to the field, such as the use of prognosis and clinical observation, the systematic categorization of diseases, or the formulation of humoral theory. The Hippocratic school of medicine revolutionized ancient Greek medicine, establishing it as a discipline distinct from other fields with which it had traditionally been associated (theurgy and philosophy), thus establishing medicine as a profession. However, the achievements of the writers of the Hippocratic Corpus, the practitioners of Hippocratic medicine, and the actions of Hippocrates himself were often conflated; thus very little is known about what Hippocrates actually t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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