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Klas Kärre
Klas Kärre (born January 12, 1954 in Strasbourg, France) is a Swedish immunologist. Kärre received his doctorate in 1981 at Karolinska Institutet and is a professor of molecular immunology at Karolinska Institutet since 1993. In the mid-1980s Kärre discovered one of the mechanisms for how cells of the immune system, natural killer cells (NK cells), identify their target cells and kill them. The findings were that the NK cells are inhibited by a transplantation antigen, the major histocompatibility complex (MHC) class I, which prevents NK cells from killing their target cells. When MHC class I is removed from the target cells, they are killed by the NK cells. Kärre named this phenomenon "the missing self hypothesis". Kärre became a member of the Nobel Committee for Physiology or Medicine in 2006 and its chairman in 2009. In 2009, he was elected a member of the Royal Swedish Academy of Sciences. Kärre is a member of the council for the Lindau Nobel Laureate Meetings. In 1998, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Strasbourg
Strasbourg (, , ; german: Straßburg ; gsw, label=Bas Rhin Alsatian, Strossburi , gsw, label=Haut Rhin Alsatian, Strossburig ) is the prefecture and largest city of the Grand Est region of eastern France and the official seat of the European Parliament. Located at the border with Germany in the historic region of Alsace, it is the prefecture of the Bas-Rhin department. In 2019, the city proper had 287,228 inhabitants and both the Eurométropole de Strasbourg (Greater Strasbourg) and the Arrondissement of Strasbourg had 505,272 inhabitants. Strasbourg's metropolitan area had a population of 846,450 in 2018, making it the eighth-largest metro area in France and home to 14% of the Grand Est region's inhabitants. The transnational Eurodistrict Strasbourg-Ortenau had a population of 958,421 inhabitants. Strasbourg is one of the ''de facto'' four main capitals of the European Union (alongside Brussels, Luxembourg and Frankfurt), as it is the seat of several European insti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nobel Committee For Physiology Or Medicine
The Nobel Committee for Physiology or Medicine is the Nobel Committee responsible for proposing laureates for the Nobel Prize for Physiology or Medicine.Nobelprize.org: The Nobel Committee for Physiology or Medicine accessed 2010-06-19 The Nobel Committee for Physiology or Medicine is appointed by the , a body of 50 members at which is formally a separate body not part of the institute ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Swedish Immunologists
Swedish or ' may refer to: Anything from or related to Sweden, a country in Northern Europe. Or, specifically: * Swedish language, a North Germanic language spoken primarily in Sweden and Finland ** Swedish alphabet, the official alphabet used by the Swedish language * Swedish people or Swedes, persons with a Swedish ancestral or ethnic identity ** A national or citizen of Sweden, see demographics of Sweden ** Culture of Sweden * Swedish cuisine See also * * Swedish Church (other) * Swedish Institute (other) * Swedish invasion (other) * Swedish Open (other) {{disambig Language and nationality disambiguation pages ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
William B
William is a male given name of Germanic origin.Hanks, Hardcastle and Hodges, ''Oxford Dictionary of First Names'', Oxford University Press, 2nd edition, , p. 276. It became very popular in the English language after the Norman conquest of England in 1066,All Things William"Meaning & Origin of the Name"/ref> and remained so throughout the Middle Ages and into the modern era. It is sometimes abbreviated "Wm." Shortened familiar versions in English include Will, Wills, Willy, Willie, Bill, and Billy. A common Irish form is Liam. Scottish diminutives include Wull, Willie or Wullie (as in Oor Wullie or the play ''Douglas''). Female forms are Willa, Willemina, Wilma and Wilhelmina. Etymology William is related to the given name ''Wilhelm'' (cf. Proto-Germanic ᚹᛁᛚᛃᚨᚺᛖᛚᛗᚨᛉ, ''*Wiljahelmaz'' > German ''Wilhelm'' and Old Norse ᚢᛁᛚᛋᛅᚼᛅᛚᛘᛅᛋ, ''Vilhjálmr''). By regular sound changes, the native, inherited English form of the name should b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lindau Nobel Laureate Meetings
The Lindau Nobel Laureate Meetings are annual scientific conferences held in Lindau, Bavaria, Germany, since 1951. Their aim is to bring together Nobel laureates and young scientists to foster scientific exchange between different generations, cultures and disciplines. The meetings assume a unique position amongst international scientific conferences, as from 30 to 65 Nobel laureates attending each edition they are the largest regular congregation of Nobel laureates in the world, apart from the Nobel Prize award ceremony in Stockholm. Purpose Every Lindau Meeting consists of a multitude of scientific sessions like plenary lectures and panel discussions as well as a variety of networking and social events. The meetings are not centered on the presentation of research results, but instead, their main goals are the exchange of ideas and the discussion of topics globally relevant to all scientists. The Nobel laureates do not receive any kind of payment for their participation and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royal Swedish Academy Of Sciences
The Royal Swedish Academy of Sciences ( sv, Kungliga Vetenskapsakademien) is one of the Swedish Royal Academies, royal academies of Sweden. Founded on 2 June 1739, it is an independent, non-governmental scientific organization that takes special responsibility for promoting natural sciences and mathematics and strengthening their influence in society, whilst endeavouring to promote the exchange of ideas between various disciplines. The goals of the academy are: * to be a forum where researchers meet across subject boundaries, * to offer a unique environment for research, * to provide support to younger researchers, * to reward outstanding research efforts, * to communicate internationally among scientists, * to advance the case for science within society and to influence research policy priorities * to stimulate interest in mathematics and science in school, and * to disseminate and popularize scientific information in various forms. Every year, the academy awards the Nobel Priz ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Major Histocompatibility Complex
The major histocompatibility complex (MHC) is a large locus on vertebrate DNA containing a set of closely linked polymorphic genes that code for cell surface proteins essential for the adaptive immune system. These cell surface proteins are called MHC molecules. This locus got its name because it was discovered via the study of transplanted tissue compatibility. Later studies revealed that tissue rejection due to incompatibility is only a facet of the full function of MHC molecules: binding an antigen derived from self-proteins, or from pathogens, and bringing the antigen presentation to the cell surface for recognition by the appropriate T-cells. MHC molecules mediate the interactions of leukocytes, also called white blood cells (WBCs), with other leukocytes or with body cells. The MHC determines donor compatibility for organ transplant, as well as one's susceptibility to autoimmune diseases. In a cell, protein molecules of the host's own phenotype or of other biologic entities ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
France
France (), officially the French Republic ( ), is a country primarily located in Western Europe. It also comprises of Overseas France, overseas regions and territories in the Americas and the Atlantic Ocean, Atlantic, Pacific Ocean, Pacific and Indian Oceans. Its Metropolitan France, metropolitan area extends from the Rhine to the Atlantic Ocean and from the Mediterranean Sea to the English Channel and the North Sea; overseas territories include French Guiana in South America, Saint Pierre and Miquelon in the North Atlantic, the French West Indies, and many islands in Oceania and the Indian Ocean. Due to its several coastal territories, France has the largest exclusive economic zone in the world. France borders Belgium, Luxembourg, Germany, Switzerland, Monaco, Italy, Andorra, and Spain in continental Europe, as well as the Kingdom of the Netherlands, Netherlands, Suriname, and Brazil in the Americas via its overseas territories in French Guiana and Saint Martin (island), ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antigen
In immunology, an antigen (Ag) is a molecule or molecular structure or any foreign particulate matter or a pollen grain that can bind to a specific antibody or T-cell receptor. The presence of antigens in the body may trigger an immune response. The term ''antigen'' originally referred to a substance that is an antibody generator. Antigens can be proteins, peptides (amino acid chains), polysaccharides (chains of monosaccharides/simple sugars), lipids, or nucleic acids. Antigens are recognized by antigen receptors, including antibodies and T-cell receptors. Diverse antigen receptors are made by cells of the immune system so that each cell has a specificity for a single antigen. Upon exposure to an antigen, only the lymphocytes that recognize that antigen are activated and expanded, a process known as clonal selection. In most cases, an antibody can only react to and bind one specific antigen; in some instances, however, antibodies may cross-react and bind more than one antigen. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Natural Killer Cell
Natural killer cells, also known as NK cells or large granular lymphocytes (LGL), are a type of cytotoxic lymphocyte critical to the innate immune system that belong to the rapidly expanding family of known innate lymphoid cells (ILC) and represent 5–20% of all circulating lymphocytes in humans. The role of NK cells is analogous to that of cytotoxic T cells in the vertebrate adaptive immune response. NK cells provide rapid responses to virus-infected cell and other intracellular pathogens acting at around 3 days after infection, and respond to tumor formation. Typically, immune cells detect the major histocompatibility complex (MHC) presented on infected cell surfaces, triggering cytokine release, causing the death of the infected cell by lysis or apoptosis. NK cells are unique, however, as they have the ability to recognize and kill stressed cells in the absence of antibodies and MHC, allowing for a much faster immune reaction. They were named "natural killers" because ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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