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Kaang Bong-kiun
Kaang Bong-Kiun (born November 21, 1961) is a South Korean professor of neuroscience in the Department of Biological Sciences of Seoul National University. He is a fellow of the Korean Academy of Science and Technology and co-director of the IBS Center for Cognition and Sociality with Changjoon Justin Lee. Early life and education Kaang was born in Jeju-do, South Korea, on November 21, 1961. He received his bachelor's degree in 1984 and his M.S. in 1986 from the Department of Microbiology, Seoul National University. During his M.S. course, he developed an interest in molecular neuroscience, particularly, in how memory is stored in the brain at the molecular level. He then went to Columbia University where he was supervised by a Nobel laureate Eric R. Kandel for his Ph.D. course and a brief postdoctoral study. He investigated the molecular mechanisms of learning and memory using a simple animal, the marine snail ''Aplysia''. Under the supervision of Dr. Kandel, he received his ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kang (Korean Surname)
Kang is a Korean family name. All together, the holders of this name number are 1,176,847 in South Korea, according to the 2015 national census, ranking 6th largest Korean family name.; While the name "Kang" can actually represent any of the 5 different hanja, or Chinese characters, the great majority (more than 1 million) bear the surname 姜. The Chinese surname Jiāng also shares the same 姜 character. Clans Clans whose surname uses the Hanja character 姜 include the clans of Jinju and Geumcheon seat. The majority belong to the Jinju Kang clan ( ko) (Hangul: 진주 강씨; Hanja: 晉州 姜氏) is said to be descended from Goguryeo commander Kang Isik. The Gumcheon Kang clan ( ko) (Hangul: 금천 강씨; Hanja: 衿川 姜氏) is descended from an ancestors whose ancestral seat was Geumcheon, now part of Seoul. Clans whose surname uses the Hanja character 康 include Sincheon ( ko) and Youngkang/Yeonggang ( ko). The Sincheon Kang clan is further subdivided into Goksan ( ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Korea
Korea ( ko, 한국, or , ) is a peninsular region in East Asia. Since 1945, it has been divided at or near the 38th parallel, with North Korea (Democratic People's Republic of Korea) comprising its northern half and South Korea (Republic of Korea) comprising its southern half. Korea consists of the Korean Peninsula, Jeju Island, and several minor islands near the peninsula. The peninsula is bordered by China to the northwest and Russia to the northeast. It is separated from Japan to the east by the Korea Strait and the Sea of Japan (East Sea). During the first half of the 1st millennium, Korea was divided between three states, Goguryeo, Baekje, and Silla, together known as the Three Kingdoms of Korea. In the second half of the 1st millennium, Silla defeated and conquered Baekje and Goguryeo, leading to the "Unified Silla" period. Meanwhile, Balhae formed in the north, superseding former Goguryeo. Unified Silla eventually collapsed into three separate states due to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anterior Cingulate Cortex
In the human brain, the anterior cingulate cortex (ACC) is the frontal part of the cingulate cortex that resembles a "collar" surrounding the frontal part of the corpus callosum. It consists of Brodmann areas 24, 32, and 33. It is involved in certain higher-level functions, such as attention allocation, reward anticipation, decision-making, ethics and morality, impulse control (e.g. performance monitoring and error detection), and emotion. Anatomy The anterior cingulate cortex can be divided anatomically based on cognitive (dorsal), and emotional (ventral) components. The dorsal part of the ACC is connected with the prefrontal cortex and parietal cortex, as well as the motor system and the frontal eye fields, making it a central station for processing top-down and bottom-up stimuli and assigning appropriate control to other areas in the brain. By contrast, the ventral part of the ACC is connected with the amygdala, nucleus accumbens, hypothalamus, hippocampus, and ant ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Toronto
The University of Toronto (UToronto or U of T) is a public research university in Toronto, Ontario, Canada, located on the grounds that surround Queen's Park. It was founded by royal charter in 1827 as King's College, the first institution of higher learning in Upper Canada. Originally controlled by the Church of England, the university assumed its present name in 1850 upon becoming a secular institution. As a collegiate university, it comprises eleven colleges each with substantial autonomy on financial and institutional affairs and significant differences in character and history. The university maintains three campuses, the oldest of which, St. George, is located in downtown Toronto. The other two satellite campuses are located in Scarborough and Mississauga. The University of Toronto offers over 700 undergraduate and 200 graduate programs. In all major rankings, the university consistently ranks in the top ten public universities in the world and as the top university ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Min Zhuo
Min Zhuo (born 1964) is a pain neuroscientist at the University of Toronto in Canada. He is also the Michael Smith Chair in Neuroscience and Mental Health as well as the Canada Research Chair in Pain and Cognition and a Fellow of the Royal Society of Canada. Supported by thHeidelberg Pain Consortium Zhou was hosted in 2017-2018 as a Guest Professor at the Pharmacology Institute at Heidelberg University, Heidelberg. Education At the age of 16, Zhuo was admitted to the University of Science and Technology of China in Hefei — graduating in 1985. He obtained his PhD at the University of Iowain Professor Jerry Gebhart's laboratory. In 1992, Zhuo joined Eric Kandel's laboratory at Columbia University where he showed CO-cGMP as key messengers for presynaptic LTP. In 1995, Zhuo spent one year in Richard Tsien's laboratory at Stanford University. In 1996, Zhuo moved to Washington University in St. Louis and focused on pain plasticity in the spinal cord and cortex. He showed th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Autism
The autism spectrum, often referred to as just autism or in the context of a professional diagnosis autism spectrum disorder (ASD) or autism spectrum condition (ASC), is a neurodevelopmental condition (or conditions) characterized by difficulties in social interaction, verbal and nonverbal communication, and the presence of repetitive behavior and restricted interests. Other common signs include unusual responses to sensory stimuli. Autism is generally understood as a ''spectrum disorder'', which means that it can manifest differently in each person: any given autistic individual is likely to show some, but not all, of the characteristics associated with it, and the person may exhibit them to varying degrees. Some autistic people remain nonspeaking over the course of their lifespan, while others have relatively unimpaired spoken language. There is large variation in the level of support people require, and the same person may present differently at varying times. Historically ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Psychiatric Disorders
A mental disorder, also referred to as a mental illness or psychiatric disorder, is a behavioral or mental pattern that causes significant distress or impairment of personal functioning. Such features may be persistent, relapsing and remitting, or occur as single episodes. Many disorders have been described, with signs and symptoms that vary widely between specific disorders. Such disorders may be Medical diagnosis, diagnosed by a mental health professional, usually a Clinical psychology#Professional practice, clinical psychologist or psychiatrist. The causes of mental disorders are often unclear. Theories may incorporate findings from a range of fields. Mental disorders are usually defined by a combination of how a person behaves, feels, perceives, or thinks. This may be associated with particular regions or functions of the brain, often in a society, social context. A mental disorder is one aspect of mental health. Cultural and religious beliefs, as well as Norm (social), ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Symptoms
Signs and symptoms are the observed or detectable signs, and experienced symptoms of an disease, illness, injury, or condition. A sign for example may be a higher or lower temperature than normal, raised or lowered blood pressure or an abnormality showing on a Medical imaging, medical scan. A symptom is something out of the ordinary that is experienced by an individual such as feeling feverish, a headache or other pain or pains in the body. Signs and symptoms Signs A medical sign is an Objectivity (science), objective observable indication of a disease, injury, or abnormal physiological state that may be detected during a physical examination, examining the patient history, or diagnostic procedure. These signs are visible or otherwise detectable such as a rash or hematoma, bruise. Medical signs, along with symptoms, assist in formulating diagnostic hypothesis. Examples of signs include hypertension, elevated blood pressure, nail clubbing of the fingernails or toenails, staggerin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polyubiquitination
Ubiquitin is a small (8.6 kDa) regulatory protein found in most tissues of eukaryotic organisms, i.e., it is found ''ubiquitously''. It was discovered in 1975 by Gideon Goldstein and further characterized throughout the late 1970s and 1980s. Four genes in the human genome code for ubiquitin: UBB, UBC, UBA52 and RPS27A. The addition of ubiquitin to a substrate protein is called ubiquitylation (or, alternatively, ubiquitination or ubiquitinylation). Ubiquitylation affects proteins in many ways: it can mark them for degradation via the proteasome, alter their cellular location, affect their activity, and promote or prevent protein interactions. Ubiquitylation involves three main steps: activation, conjugation, and ligation, performed by ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin ligases (E3s), respectively. The result of this sequential cascade is to bind ubiquitin to lysine residues on the protein substrate via an isopeptide bond, cy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hippocampus
The hippocampus (via Latin from Greek , 'seahorse') is a major component of the brain of humans and other vertebrates. Humans and other mammals have two hippocampi, one in each side of the brain. The hippocampus is part of the limbic system, and plays important roles in the consolidation of information from short-term memory to long-term memory, and in spatial memory that enables navigation. The hippocampus is located in the allocortex, with neural projections into the neocortex in humans, as well as primates. The hippocampus, as the medial pallium, is a structure found in all vertebrates. In humans, it contains two main interlocking parts: the hippocampus proper (also called ''Ammon's horn''), and the dentate gyrus. In Alzheimer's disease (and other forms of dementia), the hippocampus is one of the first regions of the brain to suffer damage; short-term memory loss and disorientation are included among the early symptoms. Damage to the hippocampus can also result from ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Behavioral
Behavior (American English) or behaviour (British English) is the range of actions and mannerisms made by individuals, organisms, systems or artificial entities in some environment. These systems can include other systems or organisms as well as the inanimate physical environment. It is the computed response of the system or organism to various stimuli or inputs, whether internal or external, conscious or subconscious, overt or covert, and voluntary or involuntary. Taking a behavior informatics perspective, a behavior consists of actor, operation, interactions, and their properties. This can be represented as a behavior vector. Models Biology Although disagreement exists as to how to precisely define behavior in a biological context, one common interpretation based on a meta-analysis of scientific literature states that "behavior is the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal and/or external stim ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electrophysiological
Electrophysiology (from Greek , ''ēlektron'', "amber" etymology of "electron"">Electron#Etymology">etymology of "electron" , ''physis'', "nature, origin"; and , ''-logia'') is the branch of physiology that studies the electrical properties of biological cells and tissues. It involves measurements of voltage changes or electric current or manipulations on a wide variety of scales from single ion channel proteins to whole organs like the heart. In neuroscience, it includes measurements of the electrical activity of neurons, and, in particular, action potential activity. Recordings of large-scale electric signals from the nervous system, such as electroencephalography, may also be referred to as electrophysiological recordings. They are useful for electrodiagnosis and monitoring. Definition and scope Classical electrophysiological techniques Principle and mechanisms Electrophysiology is the branch of physiology that pertains broadly to the flow of ions (ion current) in biol ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
