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Julian Gough (scientist)
Julian John Thurstan Gough (born 1974) is a Group Leader in the Laboratory of Molecular Biology (LMB) of the Medical Research Council (MRC). He was previously a professor of bioinformatics at the University of Bristol. Education Gough was educated at The Perse School in Cambridge and the University of Bristol where he was awarded a joint honours degree in Mathematics and Physics in 1998. He went on to complete his PhD in the Laboratory of Molecular Biology (LMB) supervised by Cyrus Chothia on genome analysis and protein structure as a postgraduate student of Sidney Sussex College, Cambridge, graduating in 2001. Career and research Following his PhD, Gough completed postdoctoral research at the LMB and Stanford University, with Michael Levitt. Subsequently, he was a scientist at RIKEN in Tokyo before being appointed a member of faculty at the University of Bristol, where he has worked since 2007. He has also been a visiting scientist at the Pasteur Institute in Paris and an a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bioinformatics
Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combines biology, chemistry, physics, computer science, information engineering, mathematics and statistics to analyze and interpret the biological data. Bioinformatics has been used for '' in silico'' analyses of biological queries using computational and statistical techniques. Bioinformatics includes biological studies that use computer programming as part of their methodology, as well as specific analysis "pipelines" that are repeatedly used, particularly in the field of genomics. Common uses of bioinformatics include the identification of candidates genes and single nucleotide polymorphisms (SNPs). Often, such identification is made with the aim to better understand the genetic basis of disease, unique adaptations, desirable properties (e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cambridge
Cambridge ( ) is a university city and the county town in Cambridgeshire, England. It is located on the River Cam approximately north of London. As of the 2021 United Kingdom census, the population of Cambridge was 145,700. Cambridge became an important trading centre during the Roman and Viking ages, and there is archaeological evidence of settlement in the area as early as the Bronze Age. The first town charters were granted in the 12th century, although modern city status was not officially conferred until 1951. The city is most famous as the home of the University of Cambridge, which was founded in 1209 and consistently ranks among the best universities in the world. The buildings of the university include King's College Chapel, Cavendish Laboratory, and the Cambridge University Library, one of the largest legal deposit libraries in the world. The city's skyline is dominated by several college buildings, along with the spire of the Our Lady and the English Martyrs ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hidden Markov Model
A hidden Markov model (HMM) is a statistical Markov model in which the system being modeled is assumed to be a Markov process — call it X — with unobservable ("''hidden''") states. As part of the definition, HMM requires that there be an observable process Y whose outcomes are "influenced" by the outcomes of X in a known way. Since X cannot be observed directly, the goal is to learn about X by observing Y. HMM has an additional requirement that the outcome of Y at time t=t_0 must be "influenced" exclusively by the outcome of X at t=t_0 and that the outcomes of X and Y at t handwriting recognition, handwriting, gesture recognition, part-of-speech tagging, musical score following, partial discharges and bioinformatics. Definition Let X_n and Y_n be discrete-time stochastic processes and n\geq 1. The pair (X_n,Y_n) is a ''hidden Markov model'' if * X_n is a Markov process whose behavior is not directly observable ("hidden"); * \operatorname\bigl(Y_n \i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genomics
Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dimensional structural configuration. In contrast to genetics, which refers to the study of ''individual'' genes and their roles in inheritance, genomics aims at the collective characterization and quantification of ''all'' of an organism's genes, their interrelations and influence on the organism. Genes may direct the production of proteins with the assistance of enzymes and messenger molecules. In turn, proteins make up body structures such as organs and tissues as well as control chemical reactions and carry signals between cells. Genomics also involves the sequencing and analysis of genomes through uses of high throughput DNA sequencing and bioinformatics to assemble and analyze the function and structure of entire genomes. Advances in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecular Biology
Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physical structure of biological macromolecules is known as molecular biology. Molecular biology was first described as an approach focused on the underpinnings of biological phenomena - uncovering the structures of biological molecules as well as their interactions, and how these interactions explain observations of classical biology. In 1945 the term molecular biology was used by physicist William Astbury. In 1953 Francis Crick, James Watson, Rosalind Franklin, and colleagues, working at Medical Research Council unit, Cavendish laboratory, Cambridge (now the MRC Laboratory of Molecular Biology), made a double helix model of DNA which changed the entire research scenario. They proposed the DNA structure based on previous research done by Ro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Computational Biology
Computational biology refers to the use of data analysis, mathematical modeling and computational simulations to understand biological systems and relationships. An intersection of computer science, biology, and big data, the field also has foundations in applied mathematics, chemistry, and genetics. It differs from biological computing, a subfield of computer engineering which uses bioengineering to build computers. History Bioinformatics, the analysis of informatics processes in biological systems, began in the early 1970s. At this time, research in artificial intelligence was using network models of the human brain in order to generate new algorithms. This use of biological data pushed biological researchers to use computers to evaluate and compare large data sets in their own field. By 1982, researchers shared information via punch cards. The amount of data grew exponentially by the end of the 1980s, requiring new computational methods for quickly interpreting ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Associate Professor
Associate professor is an academic title with two principal meanings: in the North American system and that of the ''Commonwealth system''. Overview In the ''North American system'', used in the United States and many other countries, it is a position between assistant professor and a full professorship. In this system an associate professorship is typically the first promotion obtained after gaining a faculty position, and in the United States it is usually connected to tenure. In the '' Commonwealth system'' (Canada included), the title associate professor is traditionally used in place of reader in certain countries.UK Academic Job Titles Explained academicpositions.com Like the reader title it ranks above senior lecturer – which corresponds to associ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Visiting Scholar
In academia, a visiting scholar, visiting researcher, visiting fellow, visiting lecturer, or visiting professor is a scholar from an institution who visits a host university to teach, lecture, or perform research on a topic for which the visitor is valued. In many cases the position is not salaried because visitor is salaried by their home institution (or partially salaried, as in some cases of sabbatical leave from US universities). Some visiting positions are salaried. Typically, a visiting scholar may stay for a couple of months or even a year,UT"Visiting Scholar". The University of Texas at Austin. though the stay can be extended. Typically, a visiting scholar is invited by the host institution, and it is not unusual for them to provide accommodation. Such an invitation is often regarded as recognizing the scholar's prominence in the field. Attracting prominent visiting scholars often allows the permanent faculty and graduate students to cooperate with prominent academic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Faculty (academic Staff)
Academic personnel, also known as faculty member or member of the faculty (in North American usage) or academics or academic staff (in British, Australia, and New Zealand usage), are vague terms that describe Teacher, teachers or research staff of a school, college, university or research institute. In British and Australian/New Zealand English "faculty" usually refers to a faculty (division), sub-division of a university (usually a group of departments), not to the employees, as it can also do in North America. Universities, community colleges and even some High school, secondary and Primary education, primary schools use the terms ''faculty'' and ''professor.'' Other institutions (e.g., teaching hospitals or not-for-profit research institutes) may likewise use the term ''faculty''. The higher education regulatory body of India, University Grants Commission (India), University Grants Commission, defines academic staff as teachers, librarians, and physical education personnel. [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Michael Levitt
Michael Levitt, ( he, מיכאל לויט; born 9 May 1947) is a South African-born biophysicist and a professor of structural biology at Stanford University, a position he has held since 1987. Levitt received the 2013 Nobel Prize in Chemistry, together with Martin Karplus and Arieh Warshel, for "the development of multiscale models for complex chemical systems". In 2018, Levitt was a founding co-editor of the '' Annual Review of Biomedical Data Science''. Early life and education Michael Levitt was born in Pretoria, South Africa, to a Jewish family from Plungė, Lithuania; his father was from Lithuania and his mother from the Czech Republic. He attended Sunnyside Primary School and then Pretoria Boys High School between 1960 and 1962. The family moved to England when he was 15. Levitt spent 1963 studying applied mathematics at the University of Pretoria. He attended King's College London, graduating with a first-class honours degree in Physics in 1967. In 1967, he visited Is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Postdoctoral Research
A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). The ultimate goal of a postdoctoral research position is to pursue additional research, training, or teaching in order to have better skills to pursue a career in academia, research, or any other field. Postdocs often, but not always, have a temporary academic appointment, sometimes in preparation for an academic faculty position. They continue their studies or carry out research and further increase expertise in a specialist subject, including integrating a team and acquiring novel skills and research methods. Postdoctoral research is often considered essential while advancing the scholarly mission of the host institution; it is expected to produce relevant publications in peer-reviewed academic journals or conferences. In some countries, postdoctoral research may lead to further formal qualificati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sidney Sussex College, Cambridge
Sidney Sussex College (referred to informally as "Sidney") is a constituent college of the University of Cambridge in England. The College was founded in 1596 under the terms of the will of Frances Sidney, Countess of Sussex (1531–1589), wife of Thomas Radclyffe, 3rd Earl of Sussex, and named after its foundress. It was from its inception an avowedly Protestant foundation;Sidney Sussex College website; history "some good and godlie moniment for the mainteynance of good learninge". In her will, Lady Frances Sidney left the sum of £5,000 together with some plate to found a new College at Cambridge University "to be called the Lady Frances Sidney Sussex College". Her executors [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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