Joseph Colt Bloodgood
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Joseph Colt Bloodgood
Joseph Colt Bloodgood (November 1, 1867 – October 22, 1935) was a prominent surgeon in the United States based in Johns Hopkins Hospital in Baltimore, Maryland. He was known for insisting on the use of rubber gloves by the entire surgical team, for advances in methods of identifying and treating benign and malignant cancers, particularly breast and bone cancers, and for advocating education of the public so they would seek routine medical examinations, even before any signs of cancer appeared. Birth and education Joseph Colt Bloodgood was born on November 1, 1867, in Milwaukee, Wisconsin, United States, son of Francis Bloodgood and Josephine Colt. He was a descendant of Frans Bloetgoet, a Dutch emigrant who had moved to Flushing, Long Island in 1658. His father and uncles were successful lawyers in Wisconsin. His brothers Francis Bloodgood Jr. and Wheeler Peckham Bloodgood were both to become prominent lawyers. He attended the University of Wisconsin, graduating with a Bachelo ...
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Milwaukee
Milwaukee ( ), officially the City of Milwaukee, is both the most populous and most densely populated city in the U.S. state of Wisconsin and the county seat of Milwaukee County. With a population of 577,222 at the 2020 census, Milwaukee is the 31st largest city in the United States, the fifth-largest city in the Midwestern United States, and the second largest city on Lake Michigan's shore behind Chicago. It is the main cultural and economic center of the Milwaukee metropolitan area, the fourth-most densely populated metropolitan area in the Midwest. Milwaukee is considered a global city, categorized as "Gamma minus" by the Globalization and World Cities Research Network, with a regional GDP of over $102 billion in 2020. Today, Milwaukee is one of the most ethnically and culturally diverse cities in the U.S. However, it continues to be one of the most racially segregated, largely as a result of early-20th-century redlining. Its history was heavily influenced ...
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Pathology
Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatment, the term is often used in a narrower fashion to refer to processes and tests that fall within the contemporary medical field of "general pathology", an area which includes a number of distinct but inter-related medical specialties that diagnose disease, mostly through analysis of tissue, cell, and body fluid samples. Idiomatically, "a pathology" may also refer to the predicted or actual progression of particular diseases (as in the statement "the many different forms of cancer have diverse pathologies", in which case a more proper choice of word would be " pathophysiologies"), and the affix ''pathy'' is sometimes used to indicate a state of disease in cases of both physical ailment (as in cardiomy ...
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Mastectomy
Mastectomy is the medical term for the surgical removal of one or both breasts, partially or completely. A mastectomy is usually carried out to treat breast cancer. In some cases, women believed to be at high risk of breast cancer have the operation as a preventive measure. Alternatively, some women can choose to have a wide local excision, also known as a lumpectomy, an operation in which a small volume of breast tissue containing the tumor and a surrounding margin of healthy tissue is removed to conserve the breast. Both mastectomy and lumpectomy are referred to as "local therapies" for breast cancer, targeting the area of the tumor, as opposed to systemic therapies, such as chemotherapy, hormonal therapy, or immunotherapy. The decision to perform a mastectomy is based on various factors, including breast size, the number of lesions, biologic aggressiveness of a breast cancer, the availability of adjuvant radiation, and the willingness of the patient to accept higher rates of t ...
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Chronic Cystic Mastitis
Fibrocystic breast changes is a condition of the breasts where there may be mastalgia, pain, breast cysts, and breast masses. The breasts may be described as "lumpy" or "doughy". Symptoms may worsen during certain parts of the menstrual cycle due to hormonal stimulation. These are normal breast changes, not associated with cancer. Risk factors include an early menarche, age at first menstrual period and either having children at a late age or not at all. It is not a disease but represents normal breast changes. Diagnosis involves ruling out breast cancer. Fibrocystic changes include fibroadenomas, fibrosis, and papillomas of the breast. Management may involve education about the condition, using a well fitting bra, and pain medication, if needed. Occasionally danazol or tamoxifen may be used for pain. It is estimated that up to 60% of women are affected. Most commonly between the ages of 30 and 50 years. Signs and symptoms The changes in fibrocystic breast disease are characte ...
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Curt Schimmelbusch
Curt Theodor Schimmelbusch (16 November 1860 – 2 August 1895) was a German physician and pathologist who invented the Schimmelbusch mask, for the safe delivery of anaesthetics to surgical patients. He was also a key figure in the development of mechanical methods of sterilisation and disinfection for surgical procedures, on which his ''Anleitung zur aseptischen Wundbehandlung'' ("Guide to the aseptic treatment of wounds") was considered a seminal work. Early life Schimmelbusch was born in Groß-Nogath, West Prussia, (located in modern-day Poland) on 16 November 1860. After initially studying natural sciences, he then studied medicine at Würzburg, Göttingen, Berlin and Halle. He was awarded his medical degree in 1886, while at Halle, where he worked with Karl Joseph Eberth. During his time at Halle, he assisted Eberth with his work on thrombosis, and the pair published a number of papers together. In 1888, he worked with Bernhard Bardenheuer in a hospital in Cologne, and in t ...
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Carcinoma In Situ
Carcinoma ''in situ'' (CIS) is a group of abnormal cells. While they are a form of neoplasm, there is disagreement over whether CIS should be classified as cancer. This controversy also depends on the exact CIS in question (i.e. cervical, skin, breast). Some authors do not classify them as cancer, however, recognizing that they can potentially become cancer. Others classify certain types as a non-invasive form of cancer. The term "pre-cancer" has also been used. These abnormal cells grow in their normal place, thus "''in situ''" (from Latin for "in its place"). For example, carcinoma ''in situ'' of the skin, also called Bowen's disease, is the accumulation of dysplastic epidermal cells within the epidermis only, that has failed to penetrate into the deeper dermis. For this reason, CIS will usually not form a tumor. Rather, the lesion is flat (in the skin, cervix, etc.) or follows the existing architecture of the organ (in the breast, lung, etc.). Exceptions include CIS of the colon ...
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Science History Institute
The Science History Institute is an institution that preserves and promotes understanding of the history of science. Located in Philadelphia, Pennsylvania, it includes a library, museum, archive, research center and conference center. It was founded in 1982 as a joint venture of the American Chemical Society and the University of Pennsylvania, as the Center for the History of Chemistry (CHOC). The American Institute of Chemical Engineers (AIChE) became a co-founder in 1984. It was renamed the Chemical Heritage Foundation (CHF) in 1992, and moved two years later to the institution's current location, 315 Chestnut Street in Old City, Philadelphia, Old City. On December 1, 2015, CHF merged with the Life Sciences Foundation, creating an organization that covers "the history of the life sciences and biotechnology together with the history of the chemical sciences and engineering." As of February 1, 2018, the organization was renamed the Science History Institute, to reflect its wide ...
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Caroline Hampton
Caroline Hampton Halsted (20 November 1861 – 27 November 1922) was a nurse who became the first to use medical gloves in the operating room. Biography Caroline Hampton was a member of a prominent southern family; her uncle, Wade Hampton III, was a Confederate General, governor of South Carolina, and a US senator. Her mother, Sally (Baxter) Hampton died in 1862 of tuberculosis. Her father, Colonel Frank Hampton, died at the Battle of Brandy Station in early 1863 during the American Civil War. Their family home Millwood was burned, and Hampton was raised by three aunts, with the expectation that she would marry well, ideally to a southern plantation owner. Against her family's wishes, she went to nursing school in New York. She trained first at Mount Sinai Hospital and then at New York Hospital, graduating in 1888. In 1889 she became chief surgical nurse at Johns Hopkins Hospital in Baltimore, working for William Stewart Halsted. Rubber gloves The impetus for Hampton's use of ...
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Coronary Thrombosis
Coronary thrombosis is defined as the formation of a blood clot inside a blood vessel of the heart. This blood clot may then restrict blood flow within the heart, leading to heart tissue damage, or a myocardial infarction, also known as a heart attack. Coronary thrombosis is most commonly caused as a downstream effect of atherosclerosis, a buildup of cholesterol and fats in the artery walls. The smaller vessel diameter allows less blood to flow and facilitates progression to a myocardial infarction. Leading risk factors for coronary thrombosis are high LDL cholesterol, smoking, sedentary lifestyle, and hypertension. Signs and symptoms A coronary thrombus is asymptomatic until it causes significant obstruction, leading to various forms of angina or eventually a myocardial infarction. Common warning symptoms are crushing chest pain, shortness of breath, and upper body discomfort. Pathogenesis Coronary thrombosis and myocardial infarction are sometimes used as synonyms, althoug ...
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Lighthouse International
Lighthouse Guild is an American charitable organization, based in New York City, devoted to vision rehabilitation and advocacy for the blind. Its mission statement is "To overcome vision impairment for people of all ages through worldwide leadership in rehabilitation services, education, research, prevention and advocacy." Formerly known as Lighthouse International, it merged with Jewish Guild Healthcare and as of January 2014 became known as Lighthouse Guild International, with the name eventually shortened to Lighthouse Guild. History During a trip to Florence, Italy, at the turn of the 20th century, sisters Winifred and Edith Holt learned of a free service that provided concert tickets to blind schoolchildren. Inspired by the notion, the sisters established the similar Lighthouse Free Ticket Bureau in New York City in 1903. The organization was incorporated in 1906 as The New York Association for the Blind and offered home counseling and instruction program for the visually im ...
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Winifred Holt
Winifred Holt (17 November 1870 – June 14, 1945) was an American sculptor and philanthropist who founded the New York Association for the Blind, later known as Lighthouse International. Early life and education Winifred Holt was born in New York on 17 November 1870, the daughter of Henry Holt and Mary Florence West Holt. Her father was a wealthy publisher, and her maternal grandfather was financier James Selby West. Her sister Edith married surgeon Joseph Colt Bloodgood. Holt was educated at the Brearley School in New York. She took lessons in sculpture, anatomy, and drawing during a visit to Florence in 1894. Career With her father's encouragement, Holt assisted at a settlement house the Bowery district of New York for several years, while also attending plays, concerts and opera performances. On another visit to Italy, in 1901, she and her sister Edith observed a group of blind students at a concert, engrossed by the music. In 1903 they started New York's Ticket Bureau for ...
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Henry Holt (publisher)
Henry Gartf Holt (January 3, 1840 – February 13, 1926), was an American book publisher and author. Life and career Henry Holt was born in Baltimore, Maryland, on January 3, 1840." He graduated from Yale University in 1862. After a year at Columbia Law School he married Mary Florence West and left school for work. He joined the publishing company of Frederick Leypoldt in 1866, which became Henry Holt and Company in 1873. Holt's company specialized in publishing and did not sell books at retail. He remained active in the company until about 1916. Seven years after his wife's death, he wed Florence Taber. Holt had 3 sons and 3 daughters. His son Roland Holt married famed dramatist Constance D'Arcy Mackay. In 1905, Henry Holt's daughters Edith and Winifred co-founded the New York Association for the Blind, now known as Lighthouse International. Edith continued to be active with this charity, which provided the opportunity for blind people to do useful work. In response to c ...
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