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Jonas Kellgren
Jonas Henrik Kellgren (11 September 1911 – 22 February 2002) was a British physician and the first professor of rheumatology in the United Kingdom at the University of Manchester. He became Vice-Chancellor of the university and dean of the institution's medical school. He was an expert adviser to the World Health Organization and earned a Canada Gairdner International Award for his work. Early life and education Kellgren was born in Surrey to father Jonas Henrik "Harry" and mother Vera. His mother was a Russian refugee, and his father was from a Swedish family of doctors. He grew up in London where his father and uncle co-ran a practice on Eaton Square, but it ended up failing and Kellgren's father passed away from influenza in 1919. Kellgren received financial aid from a "grateful patient" for his education at Bedales School and UCL Medical School. He also studied in Scandinavia on a scholarship and at St George's, University of London alongside his brother Ernst. Career Post ...
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Hindhead
Hindhead is a village in Surrey, England. It is the highest village in Surrey, with buildings at between 185 and 253 metres above sea level. It is best known as the location of the Devil's Punch Bowl, a beauty spot and site of special scientific interest, and as the site of the Hindhead crossroads, a formerly notorious congestion spot, where the A3 between Portsmouth and London was crossed by the A287 between Hook and Haslemere. The A3 now passes under Hindhead in the Hindhead Tunnel and its route along the Punch Bowl has been removed and landscaped, but the crossroads still exists for local traffic, as a double mini-roundabout.Ordnance Survey Hindhead is south-west of Guildford, the county town of Surrey, on the border with Hampshire. It is a ward in the district of Waverley, and part of the civil parish of Haslemere. The ward, which includes Beacon Hill, had a population of 4,292 at the 2011 Census. The place-name "Hindhead" is first attested in 1571, and means "hill fre ...
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Dunkirk Evacuation
The Dunkirk evacuation, codenamed Operation Dynamo and also known as the Miracle of Dunkirk, or just Dunkirk, was the evacuation of more than 338,000 Allied soldiers during the Second World War from the beaches and harbour of Dunkirk, in the north of France, between 26 May and 4 June 1940. The operation commenced after large numbers of Belgian, British, and French troops were cut off and surrounded by German troops during the six-week Battle of France. In a speech to the House of Commons, British Prime Minister Winston Churchill called this "a colossal military disaster", saying "the whole root and core and brain of the British Army" had been stranded at Dunkirk and seemed about to perish or be captured. In his "We shall fight on the beaches" speech on 4 June, he hailed their rescue as a "miracle of deliverance". After Germany invaded Poland in September 1939, France and the British Empire declared war on Germany and imposed an economic blockade. The British Expeditionary ...
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St Marylebone
Marylebone (usually , also , ) is a district in the West End of London, in the City of Westminster. Oxford Street, Europe's busiest shopping street, forms its southern boundary. An ancient parish and latterly a metropolitan borough, it merged with the boroughs of Westminster and Paddington to form the new City of Westminster in 1965. Marylebone station lies two miles north-west of Charing Cross. History Marylebone was originally an Ancient Parish formed to serve the manors (landholdings) of Lileston (in the west, which gives its name to modern Lisson Grove) and Tyburn in the east. The parish is likely to have been in place since at least the twelfth century and will have used the boundaries of the pre-existing manors. The boundaries of the parish were consistent from the late twelfth century to the creation of the Metropolitan Borough which succeeded it. Etymology The parish took its name from its church, dedicated to St Mary; the original church was built on the bank of a ...
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Amesbury, Massachusetts
Amesbury is a city in Essex County, Massachusetts, United States, located on the left bank of the Merrimack River near its mouth, upstream from Salisbury and across the river from Newburyport and West Newbury. The population was 17,366 at the 2020 United States Census. A former farming and mill town, Amesbury is today largely residential. It is one of the two northernmost towns in Massachusetts (the other being neighboring Salisbury). History Settlement period In 1637, the first English settler in the Salisbury-Amesbury region, John Bayly, crossed the Merrimack River from the new settlement at Newbury, built a log cabin, and began to clear the land for cultivation. He intended to send for his wife and children in England, but they never joined him.. He and his hired man, William Schooler, were arrested for a murder Schooler had committed. Schooler was hanged for the murder but Bayly was acquitted. Given the fishing rights on the river by the subsequent settlement, provided he w ...
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Royal College Of Physicians
The Royal College of Physicians (RCP) is a British professional membership body dedicated to improving the practice of medicine, chiefly through the accreditation of physicians by examination. Founded by royal charter from King Henry VIII in 1518, the RCP is the oldest medical college in England. It set the first international standard in the classification of diseases, and its library contains medical texts of great historical interest. The college is sometimes referred to as the Royal College of Physicians of London to differentiate it from other similarly named bodies. The RCP drives improvements in health and healthcare through advocacy, education and research. Its 40,000 members work in hospitals and communities across over 30 medical specialties with around a fifth based in over 80 countries worldwide. The college hosts six training faculties: the Faculty of Forensic and Legal Medicine, the Faculty for Pharmaceutical Medicine, the Faculty of Occupational Medicine the Fac ...
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Ankylosing Spondylitis
Ankylosing spondylitis (AS) is a type of arthritis characterized by long-term inflammation of the joints of the spine typically where the spine joins the pelvis. Occasionally areas affected may include other joints such as the shoulders or hips, eye and bowel problems may occur as well as back pain. Joint mobility in the affected areas generally worsens over time. Although the cause of ankylosing spondylitis is unknown, it is believed to involve a combination of genetic and environmental factors. More than 85% of those affected in the UK have a specific human leukocyte antigen known as the HLA-B27 antigen. The underlying mechanism is believed to be autoimmune or autoinflammatory. Diagnosis is typically based on the symptoms with support from medical imaging and blood tests. AS is a type of seronegative spondyloarthropathy, meaning that tests show no presence of rheumatoid factor (RF) antibodies. There is no known cure for AS. Treatments may include medication, exercise, ...
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Gout
Gout ( ) is a form of inflammatory arthritis characterized by recurrent attacks of a red, tender, hot and swollen joint, caused by deposition of monosodium urate monohydrate crystals. Pain typically comes on rapidly, reaching maximal intensity in less than 12 hours. The joint at the base of the big toe is affected in about half of cases. It may also result in tophi, kidney stones, or kidney damage. Gout is due to persistently elevated levels of uric acid in the blood. This occurs from a combination of diet, other health problems, and genetic factors. At high levels, uric acid crystallizes and the crystals deposit in joints, tendons, and surrounding tissues, resulting in an attack of gout. Gout occurs more commonly in those who: regularly drink beer or sugar-sweetened beverages; eat foods that are high in purines such as liver, shellfish, or anchovies; or are overweight. Diagnosis of gout may be confirmed by the presence of crystals in the joint fluid or in a deposit outsid ...
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Osteoarthritis
Osteoarthritis (OA) is a type of degenerative joint disease that results from breakdown of joint cartilage and underlying bone which affects 1 in 7 adults in the United States. It is believed to be the fourth leading cause of disability in the world. The most common symptoms are joint pain and stiffness. Usually the symptoms progress slowly over years. Initially they may occur only after exercise but can become constant over time. Other symptoms may include joint swelling, decreased range of motion, and, when the back is affected, weakness or numbness of the arms and legs. The most commonly involved joints are the two near the ends of the fingers and the joint at the base of the thumbs; the knee and hip joints; and the joints of the neck and lower back. Joints on one side of the body are often more affected than those on the other. The symptoms can interfere with work and normal daily activities. Unlike some other types of arthritis, only the joints, not internal organs, are af ...
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Manchester
Manchester () is a city in Greater Manchester, England. It had a population of 552,000 in 2021. It is bordered by the Cheshire Plain to the south, the Pennines to the north and east, and the neighbouring city of Salford to the west. The two cities and the surrounding towns form one of the United Kingdom's most populous conurbations, the Greater Manchester Built-up Area, which has a population of 2.87 million. The history of Manchester began with the civilian settlement associated with the Roman fort ('' castra'') of ''Mamucium'' or ''Mancunium'', established in about AD 79 on a sandstone bluff near the confluence of the rivers Medlock and Irwell. Historically part of Lancashire, areas of Cheshire south of the River Mersey were incorporated into Manchester in the 20th century, including Wythenshawe in 1931. Throughout the Middle Ages Manchester remained a manorial township, but began to expand "at an astonishing rate" around the turn of the 19th century. Manchest ...
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Peripheral Nerve Injuries
Nerve injury is an injury to nervous tissue. There is no single classification system that can describe all the many variations of nerve injuries. In 1941, Seddon introduced a classification of nerve injuries based on three main types of nerve fiber injury and whether there is continuity of the nerve. Usually, however, peripheral nerve injuries are classified in five stages, based on the extent of damage to both the nerve and the surrounding connective tissue, since supporting glial cells may be involved. Unlike in the central nervous system, neuroregeneration in the peripheral nervous system is possible. The processes that occur in peripheral regeneration can be divided into the following major events: Wallerian degeneration, axon regeneration/growth, and reinnervation of nervous tissue. The events that occur in peripheral regeneration occur with respect to the axis of the nerve injury. The proximal stump refers to the end of the injured neuron that is still attached to the ne ...
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Oxford
Oxford () is a city in England. It is the county town and only city of Oxfordshire. In 2020, its population was estimated at 151,584. It is north-west of London, south-east of Birmingham and north-east of Bristol. The city is home to the University of Oxford, the oldest university in the English-speaking world; it has buildings in every style of English architecture since late Anglo-Saxon. Oxford's industries include motor manufacturing, education, publishing, information technology and science. History The history of Oxford in England dates back to its original settlement in the Saxon period. Originally of strategic significance due to its controlling location on the upper reaches of the River Thames at its junction with the River Cherwell, the town grew in national importance during the early Norman period, and in the late 12th century became home to the fledgling University of Oxford. The city was besieged during The Anarchy in 1142. The university rose to dom ...
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Nuffield Orthopaedic Centre
The Nuffield Orthopaedic Centre (NOC) is an internationally renowned orthopaedic hospital, with strong affiliations to the University of Oxford. It provides routine and specialist orthopaedic surgery, plastic surgery and rheumatology services to the people of Oxfordshire. Specialist services, such as the treatment of osteomyelitis and bone tumours, and the rehabilitation of those with limb amputation, congenital deficiency and neurological disabilities, are provided for patients from across the UK and abroad. It is managed by the Oxford University Hospitals NHS Foundation Trust. History Funded by a donation from Mrs. Hannah Wingfield, the hospital began work as the Wingfield Convalescent Centre in 1872. During the First World War, it was a military hospital and was expanded by building a fresh air annexe of wooden buildings. By 1929, the Wingfield Morris Hospital badly needed rebuilding and Lord Nuffield, then Sir William Morris, donated £70,000 to build new nurses' quart ...
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