Jeannie T. Lee
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Jeannie T. Lee
Jeannie T. Lee is a Professor of Genetics (and Pathology) at Harvard Medical School and the Massachusetts General Hospital, and a Howard Hughes Medical Institute Investigator. She is known for her work on X-chromosome inactivation and for discovering the functions of a new class of epigenetic regulators known as long noncoding RNAs (lncRNAs), including Xist and Tsix. Education Jeannie T. Lee received an AB from Harvard College in Biochemistry & Molecular Biology and an MD/PhD in 1993 from the University of Pennsylvania School of Medicine. While at Harvard she worked with Nancy Kleckner on antisense regulation of Tn10 transposition. While at University of Pennsylvania School of Medicine her advisor was Robert L. Nussbaum. Her PhD research focused on Fragile X syndrome, and led to her strong interest in X chromosome inactivation and epigenetics. Then she did postdoctoral work with Rudolf Jaenisch at the Whitehead Institute , during which she discovered the nature of the X-in ...
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X-chromosome Reactivation
X chromosome reactivation (XCR) is the process by which the inactive X chromosome (the Xi) is re-activated in the cells of eutherian female mammals. Therian female mammalian cells have two X chromosomes, while males have only one, requiring X-chromosome inactivation (XCI) for sex-chromosome dosage compensation. In eutherians, XCI is the random inactivation of one of the X chromosomes, silencing its expression. Much of the scientific knowledge currently known about XCR comes from research limited to mouse models or stem cells. Partial XCR may derepress one or more genes on the Xi, and the level of restored gene expression may not be as high as it would normally be on the active X chromosome (the Xa). Complete XCR restores the Xi to Xa and erases the Epigenetics, epigenetic memory of XCI, meaning that inducing X-inactivation again will randomly select an X chromosome to silence, rather than deterministically silencing the original Xi. XCR is an emerging topic of interest for multiple ...
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American Association For The Advancement Of Science
The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsibility, and supporting scientific education and science outreach for the betterment of all humanity. It is the world's largest general scientific society, with over 120,000 members, and is the publisher of the well-known scientific journal ''Science''. History Creation The American Association for the Advancement of Science was created on September 20, 1848, at the Academy of Natural Sciences in Philadelphia, Pennsylvania. It was a reformation of the Association of American Geologists and Naturalists. The society chose William Charles Redfield as their first president because he had proposed the most comprehensive plans for the organization. According to the first constitution which was agreed to at the September 20 meeting, the goal of ...
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Harvard University Alumni
The list of Harvard University people includes notable graduates, professors, and administrators affiliated with Harvard University. For a list of notable non-graduates of Harvard, see notable non-graduate alumni of Harvard. For a list of Harvard's presidents, see President of Harvard University. Eight President of the United States, Presidents of the United States have graduated from Harvard University: John Adams, John Quincy Adams, Rutherford B. Hayes, John F. Kennedy, Franklin Delano Roosevelt, Theodore Roosevelt, George W. Bush, and Barack Obama. Bush graduated from Harvard Business School, Hayes and Obama from Harvard Law School, and the others from Harvard College. Over 150 Nobel Prize winners have been associated with the university as alumni, researchers or faculty. Nobel laureates Pulitzer Prize winners ...
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Fellows Of The American Association For The Advancement Of Science
Fellowship of the American Association for the Advancement of Science (FAAAS) is an honor accorded by the American Association for the Advancement of Science (AAAS) to distinguished persons who are members of the Association. Fellows are elected annually by the AAAS Council for "efforts on behalf of the advancement of science or its applications hichare scientifically or socially distinguished". Examples of areas in which nominees may have made significant contributions are research; teaching; technology; services to professional societies; administration in academe, industry, and government; and communicating and interpreting science to the public. The association has awarded fellowships since 1874. AAAS publishes annual update of active Fellows list, which also provides email address to verify status of non-active Fellows. See also :Fellows of the American Association for the Advancement of Science for more examples. AAAS Fellows AAAS Fellows include Nobel Prize winners ...
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American Geneticists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * ...
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Perelman School Of Medicine At The University Of Pennsylvania Alumni
Perelman ( he, פרלמן) is an Ashkenazi Jewish surname. Notable people with the surname include: * Bob Perelman (b. 1947), American poet * Chaim Perelman (1912-1984), Polish-born Belgian philosopher of law * Eliezer Ben-Yehuda () (1858-1922), Russian=Jewish lexicographer of the Hebrew language and newspaper editor * Grigori Perelman (b. 1966), Russian mathematician who proved the Poincaré conjecture * Mikhail Perelman (1923-2002), Soviet gymnast, winner of Olympic gold medal * Raymond G. Perelman (1917–2019), American businessman and philanthropist * Richard B. Perelman, author of ''Perelman's Pocket Cyclopedia of Cigars'' * Ronald Perelman (b.1943), American banker, businessman, and investor * S. J. Perelman (1904–1979), American humorist, author, and screenwriter * Sean Kanan (b. 1966 as Sean Perelman), American actor * Vadim Perelman (b. 1963), Ukrainian-born Canadian-American film director * Yakov Perelman (1882–1942), Soviet science-writer and author of popular sci ...
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Harvard Medical School Faculty
Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States and one of the most prestigious and highly ranked universities in the world. The university is composed of ten academic faculties plus Harvard Radcliffe Institute. The Faculty of Arts and Sciences offers study in a wide range of undergraduate and graduate academic disciplines, and other faculties offer only graduate degrees, including professional degrees. Harvard has three main campuses: the Cambridge campus centered on Harvard Yard; an adjoining campus immediately across Charles River in the Allston neighborhood of Boston; and the medical campus in Boston's Longwood Medical Area. Harvard's endowment is valued at $50.9 billion, making it the wealthiest academic institution in the world. Endowment inco ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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Year Of Birth Missing (living People)
A year or annus is the orbital period of a planetary body, for example, the Earth, moving in its orbit around the Sun. Due to the Earth's axial tilt, the course of a year sees the passing of the seasons, marked by change in weather, the hours of daylight, and, consequently, vegetation and soil fertility. In temperate and subpolar regions around the planet, four seasons are generally recognized: spring, summer, autumn and winter. In tropical and subtropical regions, several geographical sectors do not present defined seasons; but in the seasonal tropics, the annual wet and dry seasons are recognized and tracked. A calendar year is an approximation of the number of days of the Earth's orbital period, as counted in a given calendar. The Gregorian calendar, or modern calendar, presents its calendar year to be either a common year of 365 days or a leap year of 366 days, as do the Julian calendars. For the Gregorian calendar, the average length of the calendar year (the ...
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Foundation For The National Institutes Of Health
The Foundation for the National Institutes of Health (FNIH) is a not-for-profit, 501(c)(3) charitable organization established by the US Congress in 1990. Located in North Bethesda, MD, the FNIH raises private-sector funds, and creates and manages alliances with public and private institutions in support of the mission of the National Institutes of Health (NIH). Research programs The FNIH collaborates on biomedical research programs to advance breakthrough scientific discoveries. Research partnerships include: * Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV): a public–private partnership led by the National Institutes of Health (NIH) and coordinated by the Foundation for the National Institutes of Health (FNIH) to develop a research strategy for prioritizing and speeding development of the most promising COVID-19 vaccines and COVID-19 treatments. ACTIV brings together NIH with the United States Department of Health and Human Services agencies, includin ...
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Lurie Prize In Biomedical Sciences
The Lurie Prize in Biomedical Sciences recognizes outstanding achievement by a promising young scientist in biomedical research. It is awarded annually by the Foundation for the National Institutes of Health. Established in 2013 the award is worth $100,000 and was made possible by the gift of FNIH board member Ann Lurie. Prizewinners are selected by a jury of six distinguished biomedical researchers from a list of nominations. Recipients SourceFNIH* 2022: Anne Brunet, Andrew Dillin *2021: Xiaowei Zhuang *2020: Aviv Regev *2019: Yasmine Belkaid *2018: Zhijian “James” Chen *2017: David M. Sabatini *2016: Jeannie T. Lee *2015: Karl Deisseroth *2014: Jennifer Doudna *2013: Ruslan M. Medzhitov See also * List of biomedical science awards This list of biomedical science awards is an index to articles on notable awards for biomedical sciences, a set of sciences applying portions of natural science or formal science, or both, to knowledge, interventions, or technology that a ...
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Genetics (journal)
''Genetics'' is a monthly scientific journal publishing investigations bearing on heredity, genetics, biochemistry and molecular biology. Genetics is published by the Genetics Society of America. It has a delayed open access policy, and makes articles available online without a subscription after 12 months have elapsed since first publication. Since 2010, it is published online-only.http://www.councilscienceeditors.org/wp-content/uploads/v36n1p14-15_17.pdf George Harrison Shull George Harrison Shull (April 15, 1874 – September 28, 1954) was an eminent American plant geneticist and the younger brother of botanical illustrator and plant breeder J. Marion Shull. He was born on a farm in Clark County, Ohio, graduated fr ... was the founding editor of ''Genetics'' in 1916. Editors-in-Chief References External linksOfficial website Genetics journals Delayed open access journals English-language journals Publications established in 1916 Online-only journals {{ge ...
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