His
His or HIS may refer to: Computing * Hightech Information System, a Hong Kong graphics card company * Honeywell Information Systems * Hybrid intelligent system * Microsoft Host Integration Server Education * Hangzhou International School, in China * Harare International School in Zimbabwe * Hokkaido International School, in Japan * Hsinchu International School, in Taiwan * Hollandsch-Inlandsche School a Dutch school for native Indonesians in the Dutch East Indies Science * Bundle of His, a collection of specialized heart cells * Health information system * Hospital information system * Host identical sequence ** Human identical sequence * His-tag, a polyhistidine motif in proteins * Histidine, an amino acid * His 1 virus, a synonyms of Halspiviridae * HIS-1, a long non-coding RNA, also known as VIS1 People * Wilhelm His, Sr. (1831–1904), Swiss anatomist * Wilhelm His, Jr. (1863–1934), Swiss anatomist Places * His, Agder, a village in Arendal municipality in Agder c ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Histidine
Histidine (symbol His or H) is an essential amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated –NH3+ form under biological conditions), a carboxylic acid group (which is in the deprotonated –COO− form under biological conditions), and an imidazole side chain (which is partially protonated), classifying it as a positively charged amino acid at physiological pH. Initially thought essential only for infants, it has now been shown in longer-term studies to be essential for adults also. It is encoded by the codons CAU and CAC. Histidine was first isolated by Albrecht Kossel and Sven Gustaf Hedin in 1896. It is also a precursor to histamine, a vital inflammatory agent in immune responses. The acyl radical is histidyl. Properties of the imidazole side chain The conjugate acid (protonated form) of the imidazole side chain in histidine has a p''K''a of approximately 6.0. Thus, below a pH of 6, the imidazole ring ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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His-tag
A polyhistidine-tag is an amino acid motif in proteins that typically consists of at least six histidine (''His'') residues, often at the N- or C-terminus of the protein. It is also known as hexa histidine-tag, 6xHis-tag, His6 tag, by the US trademarked name HIS TAG (US Trademark serial number 74242707), and most commonly as His-Tag. The tag was invented by Roche, although the use of histidines and its vectors are distributed by Qiagen. Various purification kits for histidine-tagged proteins are available from Qiagen, Sigma, Thermo Scientific, GE Healthcare, Macherey-NagelCube Biotech Clontech, Bio-Radand others. MK(HQ)6 may be used for enhanced expression in ''E. coli'' and tag removal. The total number of histidine residues may vary in the tag from as low as two, to as high as 10 or more His residues. N- or C-terminal His-tags may also be followed or preceded, respectively, by a suitable amino acid sequence that facilitates removal of the polyhistidine-tag using endopeptidases. ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bundle Of His
The bundle of His (BH) or His bundle (HB) ( "hiss"Medical Terminology for Health Professions, Spiral bound Version'. Cengage Learning; 2016. . pp. 129–.) is a collection of heart muscle cells specialized for electrical conduction. As part of the electrical conduction system of the heart, it transmits the electrical impulses from the atrioventricular node (located between the atria and the ventricles) to the point of the apex of the fascicular branches via the bundle branches. The fascicular branches then lead to the Purkinje fibers, which provide electrical conduction to the ventricles, causing the cardiac muscle of the ventricles to contract at a paced interval. Function The bundle of His is an important part of the electrical conduction system of the heart, as it transmits impulses from the atrioventricular node, located at the anterior-inferior end of the interatrial septum, to the ventricles of the heart. The bundle of His branches into the left and the right bundle br ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Halspiviridae
''Halspiviridae'' is a family of viruses that consists of a single genus, ''Salterprovirus'', which consists of a single recognised species; ''Salterprovirus His1'' (hereafter, 'His1'). This virus was isolated from hypersaline water in Australia and was able to be cultured on the halophilic archaeon ''Haloarcula hispanica''. Like many other archaeoviruses, His1 has an approximately limoniform (lemon-shaped) virion. Etymology The family name, ''Halspiviridae'', is derived from halophilic and spindle-shaped, in reference to the habitat and virion morphology, respectively. The genus name, ''Salterprovirus'', is derived from salty terminal protein virus, as the linear dsDNA genome has proteins attached to the 5′ termini. Taxonomy The virion has a spindle-shaped morphology and is similar in shape to that of viruses infecting thermophilic archaea, the ''Fuselloviridae'', and His1 was originally described as a probable member of that group. However, it was later found that ther ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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His, Agder
His is a village in Arendal municipality in Agder county, Norway. The village is located in the central part of the island of Hisøya, along the Skaggerak coast. The village is the site of the historic Hisøy Church Hisøy Church ( no, Hisøy kirke) is a parish church of the Church of Norway in Arendal Municipality in Agder county, Norway. It is located in the village of His on the island of Hisøya. It is one of the churches for the Hisøy parish which is .... The main village on the island, Kolbjørnsvik lies about northeast of His, and the city centre of Arendal lies about to the northeast. References Villages in Agder Arendal {{Agder-geo-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Honeywell Information Systems
Honeywell International Inc. is an American publicly traded, multinational conglomerate corporation headquartered in Charlotte, North Carolina. It primarily operates in four areas of business: aerospace, building technologies, performance materials and technologies (PMT), and safety and productivity solutions (SPS). Honeywell is a Fortune 100 company, ranked 94th in 2021. In 2021 the corporation had a global workforce of approximately 99,000 employees, down from 113,000 in 2019. The current chairman and chief executive officer (CEO) is Darius Adamczyk. The corporation's current name, Honeywell International Inc., is a product of the merger of Honeywell Inc. and AlliedSignal in 1999. The corporation headquarters were consolidated with AlliedSignal's headquarters in Morristown, New Jersey; however, the combined company chose the name "Honeywell" because of the considerable brand recognition. Honeywell was a component of the Dow Jones Industrial Average index from 1999 to 200 ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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His, Haute-Garonne
His is a commune in the Haute-Garonne department in southwestern France. Population See also Communes of the Haute-Garonne department The following is a list of the 586 communes of the French department of Haute-Garonne. The communes cooperate in the following intercommunalities (as of 2020):Communes of Haute-Garonne {{HauteGaronne-geo-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Harare International School
Harare International School (or HIS) is an International school, international, co-educational, Day school, day school in Harare, Zimbabwe with around 415 students from Pre-kindergarten to twelfth grade. HIS is accredited with the Council of International Schools, the New England Association of Schools and Colleges, and the International Baccalaureate Organization. Harare International School is an American-sponsored institution, receiving support from the United States Embassy via an annual grant from the US Department of State's Office for Overseas Schools. Harare International School was ranked 54th out of the top 100 best high schools in Africa by Africa Almanac in 2003, based upon the quality of education, student engagement, strength and activities of alumni/alumnae, school profile, internet and news visibility. Harare International School was also ranked as one of the Top 10 High Schools in Zimbabwe in 2014. History Harare International School was founded on 8 September 1 ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Health Information System
Health informatics is the field of science and engineering that aims at developing methods and technologies for the acquisition, processing, and study of patient data, which can come from different sources and modalities, such as electronic health records, diagnostic test results, medical scans. The health domain provides an extremely wide variety of problems that can be tackled using computational techniques. Health informatics is a spectrum of multidisciplinary fields that includes study of the design, development and application of computational innovations to improve health care. The disciplines involved combines medicine fields with computing fields, in particular computer engineering, software engineering, information engineering, bioinformatics, bio-inspired computing, theoretical computer science, information systems, data science, information technology, autonomic computing, and behavior informatics. In academic institutions, medical informatics research focus on applic ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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VIS1
VIS1 (viral integration site 1), also known as HIS-1, is a long non-coding RNA. It was originally identified in mice in a screen for genes involved in the development of myeloid leukemia. In murine myeloid leukemias, this gene is a common site of viral insertion by the murine ecotropic retrovirus CasBrM It is conserved amongst vertebrates, including human, mice, cats, pigs, cattle and dogs. Expression of VIS1 is restricted to epithelial cells, leukemias and carcinomas. See also * Long noncoding RNA Long non-coding RNAs (long ncRNAs, lncRNA) are a type of RNA, generally defined as transcripts more than 200 nucleotides that are not translated into protein. This arbitrary limit distinguishes long ncRNAs from small non-coding RNAs, such as m ... References {{reflist Non-coding RNA ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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B Sharp
C or Do is the first note and semitone of the C major scale, the third note of the A minor scale (the relative minor of C major), and the fourth note (G, A, B, C) of the Guidonian hand, commonly pitched around 261.63 Hz. The actual frequency has depended on historical pitch standards, and for transposing instruments a distinction is made between written and sounding or concert pitch. It has enharmonic equivalents of B and D. In English the term ''Do'' is used interchangeably with C only by adherents of fixed Do solfège; in the movable Do system Do refers to the tonic of the prevailing key. Frequency Historically, concert pitch has varied. For an instrument in equal temperament tuned to the A440 pitch standard widely adopted in 1939, middle C has a frequency around 261.63 Hz (for other notes see piano key frequencies). Scientific pitch was originally proposed in 1713 by French physicist Joseph Sauveur and based on the numerically convenient frequency of 256 ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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He (pronoun)
In Modern English, ''he'' is a singular, masculine, third-person pronoun. Morphology In Standard Modern English, ''he'' has four shapes representing five distinct word forms: * ''he'': the nominative (subjective) form * ''him'': the accusative (objective) form (also called the oblique case)) * ''his:'' the dependent and independent genitive (possessive) forms * ''himself'': the reflexive form History Old English had a single third-person pronoun — from the Proto-Germanic demonstrative base *''khi''-, from PIE *''ko''- "this" — which had a plural and three genders in the singular. The modern pronoun '' it'' developed out of the neuter singular, starting to appear without the ''h'' in the 12th century. ''Her'' developed out of the feminine singular dative and genitive forms, while the other feminine forms and the plural were replaced with other words. The older pronoun had the following forms: In the 12th century, ''it'' started to separate and appear without an ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |