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Hazel Dockrell
Hazel Marguerite Dockrell (born 1952) is an Irish-born microbiologist and immunologist whose research has focused on immunity to the human mycobacterial diseases, leprosy and tuberculosis. She has spent most of her career at the London School of Hygiene and Tropical Medicine, where as of 2020 she is a professor of immunology. She was the first female president of the Royal Society of Tropical Medicine and Hygiene. Jimmy Whitworth of the Wellcome Trust describes her as "a marvellous ambassador for global health and research." Early life and education Dockrell was born in Ireland in 1952 and brought up in Dublin. Her father held medical and dentistry qualifications. She was educated at Alexandra School and College, Dublin, and Trinity College Dublin, where she studied natural sciences, graduating in microbiology. She moved to London for her postgraduate education. Her PhD (1978) was from the Royal Dental Hospital of London (now part of St Thomas' Hospital), researching Sj ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UK Research And Innovation
UK Research and Innovation (UKRI) is a non-departmental public body of the Government of the United Kingdom that directs research and innovation funding, funded through the science budget of the Department for Business, Energy and Industrial Strategy. History and role Established on 1 April 2018 by the Higher Education and Research Act 2017, UKRI brought nine organisations into one unified body. UKRI was created following a report by Sir Paul Nurse, the President of the Royal Society, who recommended the merger in order to increase integrative cross-disciplinary research. Working in partnership with universities, research organisations, businesses, charities and government, its mission is to foster research and development within the United Kingdom and create a positive "impact" – "push the frontiers of human knowledge and understanding", "deliver economic impact" and "create social and cultural impact". The first Chief Executive Officer of UKRI was the immunologist Professo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sjögren Syndrome
Sjögren syndrome or Sjögren's syndrome (SjS, SS) is a Chronic disease, long-term autoimmune disease that affects the body's moisture-producing (lacrimal and salivary) glands, and often seriously affects other organ systems, such as the lungs, kidneys, and nervous system. Primary symptoms are dryness (xerostomia, dry mouth and keratoconjunctivitis sicca, dry eyes), pain and fatigue. Other symptoms can include dry skin, vaginal dryness, a chronic cough, numbness in the arms and legs, fatigue (medical), feeling tired, muscle and joint pains, and thyroid problems. Those affected are also at an increased risk (15%) of lymphoma. While the exact cause is unclear, it is believed to involve a combination of Heredity, genetics and an environmental trigger such as exposure to a virus or bacterium. It can occur independently of other health problems (primary Sjögren's syndrome) or as a result of another connective tissue disorder (secondary Sjögren's syndrome). Sjögren's syndrome may be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biomarker (medicine)
In medicine, a biomarker is a measurable indicator of the severity or presence of some disease state. More generally a biomarker is anything that can be used as an indicator of a particular disease state or some other physiological state of an organism. According to the WHO, the indicator may be chemical, physical, or biological in nature - and the measurement may be functional, physiological, biochemical, cellular, or molecular. A biomarker can be a substance that is introduced into an organism as a means to examine organ function or other aspects of health. For example, rubidium chloride is used in isotopic labeling to evaluate perfusion of heart muscle. It can also be a substance whose detection indicates a particular disease state, for example, the presence of an antibody may indicate an infection. More specifically, a biomarker indicates a change in expression or state of a protein that correlates with the risk or progression of a disease, or with the susceptibility of the dis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Karachi
Karachi (; ur, ; ; ) is the most populous city in Pakistan and 12th most populous city in the world, with a population of over 20 million. It is situated at the southern tip of the country along the Arabian Sea coast. It is the former capital of Pakistan and capital of the province of Sindh. Ranked as a beta-global city, it is Pakistan's premier industrial and financial centre, with an estimated GDP of over $200 billion ( PPP) . Karachi paid $9billion (25% of whole country) as tax during fiscal year July 2021 to May 2022 according to FBR report. Karachi is Pakistan's most cosmopolitan city, linguistically, ethnically, and religiously diverse, as well as one of Pakistan's most secular and socially liberal cities. Karachi serves as a transport hub, and contains Pakistan’s two largest seaports, the Port of Karachi and Port Qasim, as well as Pakistan's busiest airport, Jinnah International Airport. Karachi is also a media center, home to news channels, film and fashi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aga Khan University
Aga Khan University is a non-profit institution and an agency of the Aga Khan Development Network. It was Founded in 1983 as Pakistan's first private university. Starting in 2000, the university expanded to Kenya, Tanzania, Uganda, the United Kingdom and Afghanistan. AKU began life as a health-sciences university. It is among the largest private health-care providers in Pakistan and East Africa. AKU hospitals were the first in those regions accredited by U.S.-based Joint Commission International. More recently, the university has initiated programmes in teacher education, the study of Muslim civilisations, journalism, early childhood development and public policy. In the near future, the university plans to launch an undergraduate liberal-arts programme to educate future leaders in a wide range of fields and establish additional graduate professional schools. History Founded in 1983 by the Prince Aga Khan IV, AKU is one of the Aga Khan Development Network agencies. * 1964: ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mycobacterium Leprae
''Mycobacterium leprae'' (also known as the leprosy bacillus or Hansen's bacillus), is one of the two species of bacteria that cause Hansen’s disease (leprosy), a chronic but curable infectious disease that damages the peripheral nerves and targets the skin, eyes, nose, and muscles. It is an acid-fast, Gram-positive, rod shaped bacterium and an obligate intracellular parasite, which means, unlike its relative ''Mycobacterium tuberculosis'', it cannot be grown in cell-free laboratory media. This is likely due to gene deletion and decay that the genome of the species has experienced via reductive evolution, which has caused the bacterium to depend heavily on its host for nutrients and metabolic intermediates. It has a narrow host range and apart from humans, the only other natural hosts are nine-banded armadillo and red squirrels. The bacteria infect mainly macrophages and Schwann cells, and are typically found congregated as a palisade. ''Mycobacterium leprae'' was sensi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
T Cell
A T cell is a type of lymphocyte. T cells are one of the important white blood cells of the immune system and play a central role in the adaptive immune response. T cells can be distinguished from other lymphocytes by the presence of a T-cell receptor (TCR) on their cell surface. T cells are born from hematopoietic stem cells, found in the bone marrow. Developing T cells then migrate to the thymus gland to develop (or mature). T cells derive their name from the thymus. After migration to the thymus, the precursor cells mature into several distinct types of T cells. T cell differentiation also continues after they have left the thymus. Groups of specific, differentiated T cell subtypes have a variety of important functions in controlling and shaping the immune response. One of these functions is immune-mediated cell death, and it is carried out by two major subtypes: CD8+ "killer" and CD4+ "helper" T cells. (These are named for the presence of the cell surface proteins CD8 or ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Keith McAdam
Keith Paul William James McAdam DL (born 13 August 1945) is a former Scottish cricketer and a specialist in tropical diseases. Cricket career McAdam was a left-handed batsman. He was born in Edinburgh. McAdam made his first-class debut for Cambridge University against Surrey in 1964. He played 19 further first-class matches for the University, the last coming against Oxford University in 1966. In his 20 first-class matches for the University, he scored 752 runs at a batting average of 19.78, with two half centuries and a highest score of 59. In 1967, he played a single first-class match for the Marylebone Cricket Club at Lord's, making his highest first-class score in the MCC first innings, scoring 63 before being dismissed by Stephen Russell. McAdam made his debut for Buckinghamshire in the 1966 Minor Counties Championship against Berkshire. He played seven Minor Counties Championship matches for Buckinghamshire between 1966 and 1968. He made his only List A appearanc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Malaria
Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. Symptoms usually begin ten to fifteen days after being bitten by an infected mosquito. If not properly treated, people may have recurrences of the disease months later. In those who have recently survived an infection, reinfection usually causes milder symptoms. This partial resistance disappears over months to years if the person has no continuing exposure to malaria. Malaria is caused by single-celled microorganisms of the ''Plasmodium'' group. It is spread exclusively through bites of infected ''Anopheles'' mosquitoes. The mosquito bite introduces the parasites from the mosquito's saliva into a person's blood. The parasites travel to the liver where they mature and reproduce. Five species of ''Plasmodium'' can infect and be spread by h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ivan Roitt
Ivan Maurice Roitt (born 30 September 1927) is a British scientist. He was educated at King Edward's School, Birmingham and Balliol College, Oxford University. He was Head of the Department of Immunology at University College London from 1967 to 1992, and is currently Honorary Director of the Centre for Investigative & Diagnostic Oncology at Middlesex University, London, and is related to multi-award winning radio producer Colin Roitt. In 1956, together with Deborah Doniach and Peter Campbell, he made the classic discovery of thyroglobulin autoantibodies in Hashimoto's thyroiditis which helped to open the whole concept of a relationship between autoimmunity and human disease. The work was extended to an intensive study of autoimmune phenomena in pernicious anemia and primary biliary cirrhosis. In 1983 he was elected a Fellow of the Royal Society, and has been elected to Honorary Membership of the Royal College of Physicians and appointed Honorary Fellow of The Royal Society of Med ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Middlesex Hospital Medical School
Middlesex Hospital was a teaching hospital located in the Fitzrovia area of London, England. First opened as the Middlesex Infirmary in 1745 on Windmill Street, it was moved in 1757 to Mortimer Street where it remained until it was finally closed in 2005. Its staff and services were transferred to various sites within the University College London Hospitals NHS Trust. The Middlesex Hospital Medical School, with a history dating back to 1746, merged with the medical school of University College London in 1987. History Development of the hospital The first Middlesex Hospital, which was named after the county of Middlesex, opened as the Middlesex Infirmary in Windmill Street in 1745. The infirmary started with 15 beds to provide medical treatment for the poor. Funding came from subscriptions and, in 1747, the hospital became the first in England to add lying-in (maternity) beds. Prior to 1773, the wards in the hospital were named as 'Mens long ward', 'Mens square ward up one pai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Vaccines & Immunotherapeutics
''Human Vaccines & Immunotherapeutics'' is a monthly peer-reviewed medical journal covering research into vaccines and immunotherapeutics in humans. It was established in 2005 as ''Human Vaccines'', and obtained its current name in 2012. It is published by Taylor & Francis and the editor-in-chief is Ronald Ellis ( FutuRx). According to the ''Journal Citation Reports'', the journal had a 2013 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 3.643. References External links * {{DEFAULTSORT:Human Vaccines and Immunotherapeutics Vaccinology journals Taylor & Francis academic journals Monthly journals Publications established in 2005 English-language journals ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
