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György Kéri
György Kéri (; January 11, 1950 – July 20, 2016) was a Hungarian biochemist, professor and Doctor of Biological Sciences (D.Sc.). His major field of research was signal transduction therapy and he participated in the development of novel drug discovery technologies and drug candidates that entered the clinical development process. Biography He studied chemistry at the Eötvös Loránd University (Budapest), where he graduated in 1973 and received a PhD in biochemistry in 1976. He worked as a postdoctoral research fellow at the University of California, San Francisco in 1978-1979. As a visiting scientist he returned to the United States 19 times for various time periods on the basis of a National Science Foundation grant and joint research programs with University of California, San Francisco and Sugen. From the Hungarian Academy of Sciences he received Candidatus of Biological Sciences (C.Sc.) in 1982 and Doctor of Biological Sciences (D.Sc.) in 1994. In 1997 he became Dr. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Budapest
Budapest (, ; ) is the capital and most populous city of Hungary. It is the ninth-largest city in the European Union by population within city limits and the second-largest city on the Danube river; the city has an estimated population of 1,752,286 over a land area of about . Budapest, which is both a city and county, forms the centre of the Budapest metropolitan area, which has an area of and a population of 3,303,786; it is a primate city, constituting 33% of the population of Hungary. The history of Budapest began when an early Celtic settlement transformed into the Roman town of Aquincum, the capital of Lower Pannonia. The Hungarians arrived in the territory in the late 9th century, but the area was pillaged by the Mongols in 1241–42. Re-established Buda became one of the centres of Renaissance humanist culture by the 15th century. The Battle of Mohács, in 1526, was followed by nearly 150 years of Ottoman rule. After the reconquest of Buda in 1686, the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Axxima Pharmaceuticals
GPC Biotech (also referred to as ''GPCbiotech'' and ''GPC-Biotech'') was a German biopharmaceutical company. The company's mission statement reads "... to discover, develop and commercialize new anticancer drugs." Founded in 1997, the company was held privately until May 2000 when an initial public offering was made on the now defunct German Neuer Markt. Subsequent to the closing of the Neuer, GPC refinanced in June 2004 through a public stock offering and listed ADRs on NASDAQ. In March 2000, the company acquired Mitotix, a United States biotechnology firm located in Cambridge, Massachusetts. This acquisition has led to the company having ~50% of its employees based in the United States and the remaining 50% in Germany. Further, the acquisition of Mitotix provided convenient proximity to GPC's long term and continuing collaboration with ALTANA Pharma AG and the ALTANA Research Institute, located in Waltham, Massachusetts Waltham ( ) is a city in Middlesex County, Massachu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2016 Deaths
This is a list of deaths of notable people, organised by year. New deaths articles are added to their respective month (e.g., Deaths in ) and then linked here. 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 See also * Lists of deaths by day * Deaths by year {{DEFAULTSORT:deaths by year ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1950 Births
Year 195 ( CXCV) was a common year starting on Wednesday (link will display the full calendar) of the Julian calendar The Julian calendar, proposed by Roman consul Julius Caesar in 46 BC, was a reform of the Roman calendar. It took effect on , by edict. It was designed with the aid of Greek mathematicians and astronomers such as Sosigenes of Alexandr .... At the time, it was known as the Year of the Consulship of Scrapula and Clemens (or, less frequently, year 948 '' Ab urbe condita''). The denomination 195 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Emperor Septimius Severus has the Roman Senate deify the previous emperor Commodus, in an attempt to gain favor with the family of Marcus Aurelius. * King Vologases V and other eastern princes support the claims of Pescennius Niger. The Roman province of Mesopotamia ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Széchenyi Prize
The Széchenyi Prize ( hu, Széchenyi-díj), named after István Széchenyi, is a prize given in Hungary by the state, replacing the former State Prize in 1990 in recognition of those who have made an outstanding contribution to academic life in Hungary. Recipients * Alex Szalay - 1991 * Agnes Heller - 1995 * János Kornai - 1994 * Vera T. Sós - 1997 * György Enyedi - 1998 * Miklós Laczkovich - 1998 * Thomas Molnar - 2000 * Gyula O. H. Katona - 2005 * Katalin Keserü - 2007 * Mihály Simai - 2007 * András Szőllősy - 2007 * László Lovász - 2008 * András Jánossy - 2009 * Mária Augusztinovics – 2010 * András Sárközy - 2010 * Mihaly Csikszentmihalyi - 2011 * László Lénárd - 2011 * Lajos Pósa - 2011 * Gábor Stépán - 2011 * Endre Szemerédi (2012) * György Kéri - 2013 * Telegdy Gyula - 2014 * Mária Schmidt, Miklós Simonovits - * Péter Erdő, Miklós Maróth (2016) * Béla Bollobás Béla Bollobás FRS (born 3 August 1943) is a Hungari ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
European Biotechnology Association
European, or Europeans, or Europeneans, may refer to: In general * ''European'', an adjective referring to something of, from, or related to Europe ** Ethnic groups in Europe ** Demographics of Europe ** European cuisine, the cuisines of Europe and other Western countries * ''European'', an adjective referring to something of, from, or related to the European Union ** Citizenship of the European Union ** Demographics of the European Union In publishing * ''The European'' (1953 magazine), a far-right cultural and political magazine published 1953–1959 * ''The European'' (newspaper), a British weekly newspaper published 1990–1998 * ''The European'' (2009 magazine), a German magazine first published in September 2009 *''The European Magazine'', a magazine published in London 1782–1826 *''The New European'', a British weekly pop-up newspaper first published in July 2016 Other uses * * Europeans (band), a British post-punk group, from Bristol See also * * * Europe (disam ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SU101
Leflunomide, sold under the brand name Arava among others, is an immunosuppressive disease-modifying antirheumatic drug (DMARD), used in active moderate-to-severe rheumatoid arthritis and psoriatic arthritis. It is a pyrimidine synthesis inhibitor that works by inhibiting dihydroorotate dehydrogenase. Medical use Rheumatoid arthritis and psoriatic arthritis are the only indications that have received regulatory approval. Arava was developed by Sanofi Aventis and approved by the U.S. Food and Drug Administration in 1998. Clinical studies regarding the following diseases have been conducted: There has been reports on potential re-purposing of leflunomide for treatment of solid tumors with tumor suppressor, PTEN, loss. In PTEN negative tumors, leflunomide causes synthetic lethality potentially due to increased demand on pyrimidines in these faster growing cells. * Polyoma BK virus nephropathy * Kimura's disease * Systemic lupus erythematosus * Felty's syndrome * Takayasu arter ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sugen
SUGEN (Sugen) was a drug discovery company focused on development of protein kinase inhibitors. It was founded in 1991, and shut down in 2003, after pioneering protein kinases as therapeutic targets and developing the successful cancer therapy sunitinib (Sutent). Early history and focus Sugen was founded in 1991 in Redwood City, California, by veteran biotech investor Stephen Evans-Freke and kinase researchers Joseph Schlessinger and Axel Ullrich. The name was derived from the initials of Schlessinger and Ullrich, and the "GEN" for Genetics. Sugen developed small-molecule inhibitors of protein kinases, key enzymes in signal transduction and cellular decision-making. The main focus was on oncology, though the company had collaborations in other therapeutic areas. The concept of inhibiting kinases by small molecules that mimicked the ATP structure was generally thought to be infeasible when the company was founded (due to the high (mM) concentration of ATP in cells), and Sugen has ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biochemistry
Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and metabolism. Over the last decades of the 20th century, biochemistry has become successful at explaining living processes through these three disciplines. Almost all areas of the life sciences are being uncovered and developed through biochemical methodology and research. Voet (2005), p. 3. Biochemistry focuses on understanding the chemical basis which allows biological molecules to give rise to the processes that occur within living cells and between cells, Karp (2009), p. 2. in turn relating greatly to the understanding of tissues and organs, as well as organism structure and function.Miller (2012). p. 62. Biochemistry is closely related to molecular biology, which is the study of the molecular mechanisms of biological phenomena.Ast ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Science Foundation
The National Science Foundation (NSF) is an independent agency of the United States government that supports fundamental research and education in all the non-medical fields of science and engineering. Its medical counterpart is the National Institutes of Health. With an annual budget of about $8.3 billion (fiscal year 2020), the NSF funds approximately 25% of all federally supported basic research conducted by the United States' colleges and universities. In some fields, such as mathematics, computer science, economics, and the social sciences, the NSF is the major source of federal backing. The NSF's director and deputy director are appointed by the President of the United States and confirmed by the United States Senate, whereas the 24 president-appointed members of the National Science Board (NSB) do not require Senate confirmation. The director and deputy director are responsible for administration, planning, budgeting and day-to-day operations of the foundation, whil ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eötvös Loránd University
Eötvös Loránd University ( hu, Eötvös Loránd Tudományegyetem, ELTE) is a Hungarian public research university based in Budapest. Founded in 1635, ELTE is one of the largest and most prestigious public higher education institutions in Hungary. The 28,000 students at ELTE are organized into nine faculties, and into research institutes located throughout Budapest and on the scenic banks of the Danube. ELTE is affiliated with 5 Nobel laureates, as well as winners of the Wolf Prize, Fulkerson Prize and Abel Prize, the latest of which was Abel Prize winner László Lovász in 2021. The predecessor of Eötvös Loránd University was founded in 1635 by Cardinal Péter Pázmány in Nagyszombat, Kingdom of Hungary (today Trnava, Slovakia) as a Catholic university for teaching theology and philosophy. In 1770, the university was transferred to Buda. It was named Royal University of Pest until 1873, then University of Budapest until 1921, when it was renamed Royal Hungarian Pázm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
