EpiVacCorona
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EpiVacCorona
EpiVacCorona ( rus, ЭпиВакКорона, EpiVacCorona) is a Peptide vaccine, peptide-based vaccine against COVID-19 vaccine, COVID-19 developed by the State Research Center of Virology and Biotechnology VECTOR, VECTOR center of Virology. The lack of protective effectiveness of EpiVacCorona, which is still in use in Russia, has been reported in scientific literature and in the media. The vaccine consists of three chemically synthesized peptides (short fragments of a viral spike protein) that are Fusion protein, conjugated to a large carrier protein. This protein is a fusion product of a viral Severe acute respiratory syndrome coronavirus 2#Structural biology, nucleocapsid protein and a bacterial Maltose-binding protein, MBP protein. A phase three clinical trial to show whether or not the vaccine can protect people against COVID-19 was launched in November 2020 with more than three thousand participants. The facts of the end of the trial and the result of the trial have not ...
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EpiVacCorona Design
EpiVacCorona ( rus, ЭпиВакКорона, EpiVacCorona) is a Peptide vaccine, peptide-based vaccine against COVID-19 vaccine, COVID-19 developed by the State Research Center of Virology and Biotechnology VECTOR, VECTOR center of Virology. The lack of protective effectiveness of EpiVacCorona, which is still in use in Russia, has been reported in scientific literature and in the media. The vaccine consists of three chemically synthesized peptides (short fragments of a viral spike protein) that are Fusion protein, conjugated to a large carrier protein. This protein is a fusion product of a viral Severe acute respiratory syndrome coronavirus 2#Structural biology, nucleocapsid protein and a bacterial Maltose-binding protein, MBP protein. A phase three clinical trial to show whether or not the vaccine can protect people against COVID-19 was launched in November 2020 with more than three thousand participants. The facts of the end of the trial and the result of the trial have not ...
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EpiVacCorona In Illustrations
EpiVacCorona ( rus, ЭпиВакКорона, EpiVacCorona) is a peptide-based vaccine against COVID-19 developed by the VECTOR center of Virology. The lack of protective effectiveness of EpiVacCorona, which is still in use in Russia, has been reported in scientific literature and in the media. The vaccine consists of three chemically synthesized peptides (short fragments of a viral spike protein) that are conjugated to a large carrier protein. This protein is a fusion product of a viral nucleocapsid protein and a bacterial MBP protein. A phase three clinical trial to show whether or not the vaccine can protect people against COVID-19 was launched in November 2020 with more than three thousand participants. The facts of the end of the trial and the result of the trial have not been made public. Some experts in the field have expressed concerns about the selection of peptides for use as vaccine antigens. In addition, there are also serious concerns about the vaccine immuno ...
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List Of COVID-19 Vaccine Authorizations
National regulatory authorities have granted full or emergency use authorizations for 40 COVID-19 vaccines. Ten vaccines have been approved for emergency or full use by at least one stringent regulatory authority recognized by the World Health Organization (WHO): Pfizer–BioNTech, Oxford–AstraZeneca, Sinopharm BIBP, Moderna, Janssen, CoronaVac, Covaxin, Novavax, Convidecia, and Sanofi–GSK. Seven others are under assessment by the WHO: Sputnik V, Sinopharm WIBP, Abdala, Zifivax, Corbevax, COVIran Barekat, and SCB-2019. Of the 40 vaccines, 16 have a full or emergency authorization in only one country, 12 in ten or fewer countries, and 12 in more than ten countries. Note that in some countries, vaccines may be authorized solely for travel purposes. They may not be approved for the general population. For example, the CoronaVac, Covishield, BBIBP-CorV and Covaxin vaccines are not part of Australia's national vaccination program; however, they are recognized for the p ...
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COVID-19 Vaccine
A COVID19 vaccine is a vaccine intended to provide acquired immunity against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), the virus that causes coronavirus disease 2019 ( COVID19). Prior to the COVID19 pandemic, an established body of knowledge existed about the structure and function of coronaviruses causing diseases like severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). This knowledge accelerated the development of various vaccine platforms during early 2020. The initial focus of SARS-CoV-2 vaccines was on preventing symptomatic, often severe illness. In January 2020, the SARS-CoV-2 genetic sequence data was shared through GISAID, and by March 2020, the global pharmaceutical industry announced a major commitment to address COVID19. In 2020, the first COVID19 vaccines were developed and made available to the public through emergency authorizations and conditional approvals. Initially, most COVID19 vaccines were two ...
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Peptide Vaccine
Peptide-based synthetic vaccines (epitope vaccines) are subunit vaccines made from peptides. The peptides mimic the epitopes of the antigen that triggers direct or potent immune responses. Peptide vaccines can not only induce protection against infectious pathogens and non-infectious diseases but also be utilized as therapeutic cancer vaccines, where peptides from tumor-associated antigens are used to induce an effective anti-tumor T-cell response. History The traditional vaccines are the whole live or fixed pathogens. The second generation of vaccines is mainly the protein purified from the pathogen. The third generation of vaccines is the DNA or plasmid that can express the proteins of the pathogen. Peptide vaccines are the latest step in the evolution of vaccines. Advantages and disadvantages Compared with the traditional vaccines such as the whole fixed pathogens or protein molecules, the peptide vaccines have several advantages and disadvantages. Advantages: * The v ...
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State Research Center Of Virology And Biotechnology VECTOR
The State Research Center of Virology and Biotechnology VECTOR, also known as the Vector Institute (russian: Государственный научный центр вирусологии и биотехнологии „Вектор“, Gosudarstvennyy nauchnyy tsentr virusologii i biotekhnologii "Vektor"), is a biological research center in Koltsovo, Novosibirsk Oblast, Russia. It has research facilities and capabilities for all levels of Biological Hazard, CDC Levels 1–4. It is one of two official repositories for the now-eradicated smallpox virus, and was part of the system of laboratories known as the Biopreparat. The facility was upgraded and secured using modern cameras, motion sensors, fences and biohazard containment systems. Its relative seclusion makes security an easier task. Since its inception there has been an army regiment guarding the facility. At least in Soviet times the facility was a nexus for biological warfare research (see Soviet biological weapons ...
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Severe Acute Respiratory Syndrome Coronavirus 2
Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the ongoing COVID-19 pandemic. The virus previously had a Novel coronavirus, provisional name, 2019 novel coronavirus (2019-nCoV), and has also been called the human coronavirus 2019 (HCoV-19 or hCoV-19). First identified in the city of Wuhan, Hubei, China, the World Health Organization declared the outbreak a public health emergency of international concern on January 30, 2020, and a pandemic on March 11, 2020. SARS‑CoV‑2 is a positive-sense single-stranded RNA virus that is Contagious disease, contagious in humans. SARS‑CoV‑2 is a virus of the species ''severe acute respiratory syndrome–related coronavirus'' (SARSr-CoV), related to the Severe acute respiratory syndrome coronavirus 1, SARS-CoV-1 virus that caused the 2002–2004 SARS outbreak. Despite its close relation to SARS-CoV-1, i ...
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Deutsche Welle
Deutsche Welle (; "German Wave" in English), abbreviated to DW, is a German public, state-owned international broadcaster funded by the German federal tax budget. The service is available in 32 languages. DW's satellite television service consists of channels in English, German, Spanish, and Arabic. The work of DW is regulated by the Deutsche Welle Act, meaning that content is intended to be independent of government influence. DW is a member of the European Broadcasting Union (EBU). DW offers regularly updated articles on its news website and runs its own center for international media development, DW Akademie. The broadcaster's stated goals are to produce reliable news coverage, provide access to the German language, and promote understanding between peoples. It is also a provider of live streaming world news which can be viewed via its website, YouTube, and various mobile devices and digital media players. DW has been broadcasting since 1953. It is headquartered in Bonn, ...
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Turkmenistan
Turkmenistan ( or ; tk, Türkmenistan / Түркменистан, ) is a country located in Central Asia, bordered by Kazakhstan to the northwest, Uzbekistan to the north, east and northeast, Afghanistan to the southeast, Iran to the south and southwest and the Caspian Sea to the west. Ashgabat is the capital and largest city. The population is about 6 million, the lowest of the Central Asian republics, and Turkmenistan is one of the most sparsely populated nations in Asia. Turkmenistan has long served as a thoroughfare for other nations and cultures. Merv is one of the oldest oasis-cities in Central Asia, and was once the biggest city in the world. It was also one of the great cities of the Islamic world and an important stop on the Silk Road. Annexed by the Russian Empire in 1881, Turkmenistan figured prominently in the anti-Bolshevik movement in Central Asia. In 1925, Turkmenistan became a constituent republic of the Soviet Union, the Turkmen Soviet Socialist Repu ...
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World Health Organization
The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of health". Headquartered in Geneva, Switzerland, it has six regional offices and 150 field offices worldwide. The WHO was established on 7 April 1948. The first meeting of the World Health Assembly (WHA), the agency's governing body, took place on 24 July of that year. The WHO incorporated the assets, personnel, and duties of the League of Nations' Health Organization and the , including the International Classification of Diseases (ICD). Its work began in earnest in 1951 after a significant infusion of financial and technical resources. The WHO's mandate seeks and includes: working worldwide to promote health, keeping the world safe, and serve the vulnerable. It advocates that a billion more people should have: universal health care coverag ...
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Delcy Rodríguez
Delcy Eloína Rodríguez Gómez (born 18 May 1969) is a Venezuelan politician serving as the vice president of Venezuela since 2018. She was also Minister of Popular Power for Communication and Information of Venezuela from 2013 to 2014, Minister of Foreign Affairs from 2014 to 2017 and President of the Constituent Assembly of Venezuela from 4 August 2017 to 14 June 2018. She is the target of multiple international sanctions. Political career She held several posts during the course of the Chavez administration: as International Affairs Director in the Ministry of Energy and Mines, in 2003; as Vice-minister for European Affairs in 2005; serving from February–August 2006 as the Minister for Presidential Affairs and the following year as General Coordinator to the Vice-President of Venezuela, both of which roles she held while her brother occupied the office of Vice President of the Republic. She was the Minister for Presidential Affairs in 2006. Similarly, she was Vice Min ...
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Soumya Swaminathan
Soumya Swaminathan (born 2 May 1959) is an Indian paediatrician and clinical scientist known for her research on tuberculosis and HIV. From 2019 to 2022, she served as the chief scientist at the World Health Organization under the leadership of Director General Tedros Adhanom Ghebreyesus. Previously, from October 2017 to March 2019, she was the Deputy Director General of Programmes (DDP) at the World Health Organization. Early life and education Swaminathan was born in Chennai, India. Swaminathan is the daughter of "Father of Green Revolution of India", M. S. Swaminathan and Indian educationalist Mina Swaminathan. Swaminathan has two siblings, Madhura Swaminathan, a professor of economics at the Indian Statistical Institute, Bangalore, and Nithya Swaminathan, a senior lecturer in gender analysis in international development at the University of East Anglia. Swaminathan received an M.B.B.S. from the Armed Forces Medical College in Pune. She has an M.D. in pediatrics from All Ind ...
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