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Enzo Emanuele
Enzo Emanuele (born June 10, 1977) is an Italian clinical pathologist known for his interdisciplinary research in the field of biological psychology. He has studied the biochemical basis of romantic interpersonal attraction and identified the neurotrophin nerve growth factor (NGF) as a key biochemical mediator of falling in love. The implications of this research have been criticized in the popular press. In 2008, his genetic research, which showed an association between serotonin and dopamine receptor gene polymorphisms and certain love traits, was awarded with the International Zdenek Klein Award for Human Ethology from the Charles University in Prague, Czech Republic. Emanuele is also known for his studies on biomarkers of atherosclerosis. On October 3, 2009, Enzo Emanuele was awarded by the Italian Society for the Study of Atherosclerosis (SISA), Lombardy Section, with the Giovanni Galli Prize for his scientific contributions in the field of cardiovascular biomarkers. He ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Novara
Novara (, Novarese: ) is the capital city of the province of Novara in the Piedmont region in northwest Italy, to the west of Milan. With 101,916 inhabitants (on 1 January 2021), it is the second most populous city in Piedmont after Turin. It is an important crossroads for commercial traffic along the routes from Milan to Turin and from Genoa to Switzerland. Novara lies between the rivers Agogna and Terdoppio in northeastern Piedmont, from Milan and from Turin. History Novara was founded around 89 BC by the Romans, when the local Gauls obtained the Roman citizenship. Its name is formed from ''Nov'', meaning "new", and ''Aria'', the name the Cisalpine Gauls used for the surrounding region. Ancient ''Novaria'', which dates to the time of the Ligures and the Celts, was a municipium and was situated on the road from Vercellae (Vercelli) to (Mediolanum) Milan. Its position on perpendicular roads (still intact today) dates to the time of the Romans. After the city was destroyed in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Serotonin
Serotonin () or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter. Its biological function is complex and multifaceted, modulating mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vasoconstriction. Approximately 90% of the serotonin that the body produces is in the intestinal tract. Biochemically, the indoleamine molecule derives from the amino acid tryptophan, via the (rate-limiting) hydroxylation of the 5 position on the ring (forming the intermediate 5-hydroxytryptophan), and then decarboxylation to produce serotonin. Serotonin is primarily found in the enteric nervous system located in the gastrointestinal tract (GI tract). However, it is also produced in the central nervous system (CNS), specifically in the raphe nuclei located in the brainstem, Merkel cells located in the skin, pulmonary neuroendocrine cells and taste receptor cells in the tongue. Additionally, serotonin is stored in blood platelets and is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atherosclerosis
Atherosclerosis is a pattern of the disease arteriosclerosis in which the wall of the artery develops abnormalities, called lesions. These lesions may lead to narrowing due to the buildup of atheroma, atheromatous plaque. At onset there are usually no symptoms, but if they develop, symptoms generally begin around middle age. When severe, it can result in coronary artery disease, stroke, peripheral artery disease, or kidney problems, depending on which Artery, arteries are affected. The exact cause is not known and is proposed to be multifactorial. Risk factors include dyslipidemia, abnormal cholesterol levels, elevated levels of inflammatory markers, high blood pressure, diabetes, smoking, obesity, family history, genetic, and an unhealthy diet. Atheroma, Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood. The narrowing of Artery, arteries limits the flow of oxygen-rich blood to parts of the body. Diagnosis is based upon a physical exam, ele ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RAGE (receptor)
RAGE ( receptor for advanced glycation endproducts), also called AGER, is a 35 kilodalton transmembrane receptor of the immunoglobulin super family which was first characterized in 1992 by Neeper ''et al.'' Its name comes from its ability to bind advanced glycation endproducts (AGE), which include chiefly glycoproteins, the glycans of which have been modified non-enzymatically through the Maillard reaction. In view of its inflammatory function in innate immunity and its ability to detect a class of ligands through a common structural motif, RAGE is often referred to as a pattern recognition receptor. RAGE also has at least one other agonistic ligand: high mobility group protein B1 (HMGB1). HMGB1 is an intracellular DNA-binding protein important in chromatin remodeling which can be released by necrotic cells passively, and by active secretion from macrophages, natural killer cells, and dendritic cells. The interaction between RAGE and its ligands is thought to result in pro- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pavia
Pavia (, , , ; la, Ticinum; Medieval Latin: ) is a town and comune of south-western Lombardy in northern Italy, south of Milan on the lower Ticino river near its confluence with the Po. It has a population of c. 73,086. The city was the capital of the Ostrogothic Kingdom from 540 to 553, of the Kingdom of the Lombards from 572 to 774, of the Kingdom of Italy from 774 to 1024 and seat of the Visconti court from 1365 to 1413. Pavia is the capital of the fertile province of Pavia, which is known for a variety of agricultural products, including wine, rice, cereals, and dairy products. Although there are a number of industries located in the suburbs, these tend not to disturb the peaceful atmosphere of the town. It is home to the ancient University of Pavia (founded in 1361 and recognized in 2022 by the Times Higher Education among the top 10 in Italy and among the 300 best in the world), which together with the IUSS (Institute for Advanced Studies of Pavia), Ghislieri College, B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physician
A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the study, diagnosis, prognosis and treatment of disease, injury, and other physical and mental impairments. Physicians may focus their practice on certain disease categories, types of patients, and methods of treatment—known as specialities—or they may assume responsibility for the provision of continuing and comprehensive medical care to individuals, families, and communities—known as general practice. Medical practice properly requires both a detailed knowledge of the academic disciplines, such as anatomy and physiology, underlying diseases and their treatment—the ''science'' of medicine—and also a decent competence in its applied practice—the art or ''craft'' of medicine. Both the role of the physician and the meaning ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prize
A prize is an award to be given to a person or a group of people (such as sporting teams and organizations) to recognize and reward their actions and achievements.Prize definition 1, The Free Dictionary, Farlex, Inc. Retrieved August 7, 2009. Official prizes often involve money, monetary rewards as well as the fame that comes with them. Some prizes are also associated with extravagant awarding ceremonies, such as the Academy Awards. Prizes are also given to publicize noteworthy or exemplary behaviour, and to provide incentives for improved outcomes and competitive efforts. In general, prizes are regarded in a positive light, and their winners are admired. However, many prizes, especially the more famous ones, have often caused controversy and jealousy. Specific types of prizes include: * Booby prize: typically awarded as a joke or ins ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lombardy
Lombardy ( it, Lombardia, Lombard language, Lombard: ''Lombardia'' or ''Lumbardia' '') is an administrative regions of Italy, region of Italy that covers ; it is located in the northern-central part of the country and has a population of about 10 million people, constituting more than one-sixth of Italy's population. Over a fifth of the Italian gross domestic product (GDP) is produced in the region. The Lombardy region is located between the Alps mountain range and tributaries of the Po river, and includes Milan, the largest metropolitan area in the country, and among the largest in the European Union (EU). Of the fifty-eight UNESCO World Heritage Sites in Italy, eleven are in Lombardy. Virgil, Pliny the Elder, Ambrose, Gerolamo Cardano, Caravaggio, Claudio Monteverdi, Antonio Stradivari, Cesare Beccaria, Alessandro Volta and Alessandro Manzoni; and popes Pope John XXIII, John XXIII and Pope Paul VI, Paul VI originated in the area of modern-day Lombardy region. Etymology The name ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atherosclerosis
Atherosclerosis is a pattern of the disease arteriosclerosis in which the wall of the artery develops abnormalities, called lesions. These lesions may lead to narrowing due to the buildup of atheroma, atheromatous plaque. At onset there are usually no symptoms, but if they develop, symptoms generally begin around middle age. When severe, it can result in coronary artery disease, stroke, peripheral artery disease, or kidney problems, depending on which Artery, arteries are affected. The exact cause is not known and is proposed to be multifactorial. Risk factors include dyslipidemia, abnormal cholesterol levels, elevated levels of inflammatory markers, high blood pressure, diabetes, smoking, obesity, family history, genetic, and an unhealthy diet. Atheroma, Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood. The narrowing of Artery, arteries limits the flow of oxygen-rich blood to parts of the body. Diagnosis is based upon a physical exam, ele ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Czech Republic
The Czech Republic, or simply Czechia, is a landlocked country in Central Europe. Historically known as Bohemia, it is bordered by Austria to the south, Germany to the west, Poland to the northeast, and Slovakia to the southeast. The Czech Republic has a hilly landscape that covers an area of with a mostly temperate continental and oceanic climate. The capital and largest city is Prague; other major cities and urban areas include Brno, Ostrava, Plzeň and Liberec. The Duchy of Bohemia was founded in the late 9th century under Great Moravia. It was formally recognized as an Imperial State of the Holy Roman Empire in 1002 and became a kingdom in 1198. Following the Battle of Mohács in 1526, the whole Crown of Bohemia was gradually integrated into the Habsburg monarchy. The Protestant Bohemian Revolt led to the Thirty Years' War. After the Battle of White Mountain, the Habsburgs consolidated their rule. With the dissolution of the Holy Empire in 1806, the Cro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Charles University In Prague
Charles University ( cs, Univerzita Karlova, UK; la, Universitas Carolina; german: Karls-Universität), also known as Charles University in Prague or historically as the University of Prague ( la, Universitas Pragensis, links=no), is the oldest and largest university in the Czech Republic. It is one of the List of oldest universities in continuous operation, oldest universities in Europe in continuous operation. Today, the university consists of 17 faculties located in Prague, Hradec Králové, and Plzeň. Charles University belongs among the top three universities in Central and Eastern Europe. It is ranked around 200–300 in the world. History Medieval university (1349–1419) The establishment of a medieval university in Prague was inspired by Holy Roman Emperor Charles IV, Holy Roman Emperor, Charles IV. He asked his friend and ally, Pope Clement VI, to do so. On 26 January 1347 the pope issued the bull establishing a university in Prague, modeled on the University of Paris, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ethology
Ethology is the scientific study of animal behaviour, usually with a focus on behaviour under natural conditions, and viewing behaviour as an evolutionarily adaptive trait. Behaviourism as a term also describes the scientific and objective study of animal behaviour, usually referring to measured responses to stimuli or to trained behavioural responses in a laboratory context, without a particular emphasis on evolutionary adaptivity. Throughout history, different naturalists have studied aspects of animal behaviour. Ethology has its scientific roots in the work of Charles Darwin and of American and German ornithologists of the late 19th and early 20th century, including Charles O. Whitman, Oskar Heinroth, and Wallace Craig. The modern discipline of ethology is generally considered to have begun during the 1930s with the work of Dutch biologist Nikolaas Tinbergen and Austrian biologists Konrad Lorenz and Karl von Frisch, the three recipients of the 1973 Nobel Prize in Phys ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
