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Ecovirology
Virology is the Scientific method, scientific study of biological viruses. It is a subfield of microbiology that focuses on their detection, structure, classification and evolution, their methods of infection and exploitation of host (biology), host cell (biology), cells for reproduction, their interaction with host organism physiology and immunity, the diseases they cause, the techniques to isolate and culture them, and their use in research and therapy. The identification of the causative agent of tobacco mosaic disease (TMV) as a novel pathogen by Martinus Beijerinck (1898) is now acknowledged as being the history of virology, official beginning of the field of virology as a discipline distinct from bacteriology. He realized the source was neither a bacterial nor a fungal infection, but something completely different. Beijerinck used the word "virus" to describe the mysterious agent in his 'contagium vivum fluidum' ('contagious living fluid'). Rosalind Franklin proposed the f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gamma Phage
Gamma (uppercase , lowercase ; ''gámma'') is the third letter of the Greek alphabet. In the system of Greek numerals it has a value of 3. In Ancient Greek, the letter gamma represented a voiced velar stop . In Modern Greek, this letter represents either a voiced velar fricative or a voiced palatal fricative (while /g/ in foreign words is instead commonly transcribed as γκ). In the International Phonetic Alphabet and other modern Latin-alphabet based phonetic notations, it represents the voiced velar fricative. History The Greek letter Gamma Γ is a grapheme derived from the Phoenician letter (''gīml'') which was rotated from the right-to-left script of Canaanite to accommodate the Greek language's writing system of left-to-right. The Canaanite grapheme represented the /g/ phoneme in the Canaanite language, and as such is cognate with ''gimel'' ג of the Hebrew alphabet. Based on its name, the letter has been interpreted as an abstract representation of a camel's ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bacteria
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the first life forms to appear on Earth, and are present in most of its habitats. Bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of Earth's crust. Bacteria are vital in many stages of the nutrient cycle by recycling nutrients such as the fixation of nitrogen from the atmosphere. The nutrient cycle includes the decomposition of dead bodies; bacteria are responsible for the putrefaction stage in this process. In the biological communities surrounding hydrothermal vents and cold seeps, extremophile bacteria provide the nutrients needed to sustain life by converting dissolved compounds, such as hydrogen sulphide and methane, to energy. Bacteria also live in symbiotic and parasitic relationsh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aphthovirus
''Aphthovirus'' (from the Greek -, vesicles in the mouth) is a viral genus of the family ''Picornaviridae''. Aphthoviruses infect split-hooved animals, and include the causative agent of foot-and-mouth disease, ''Foot-and-mouth disease virus'' (FMDV). There are seven FMDV serotypes: A, O, C, SAT 1, SAT 2, SAT 3 and Asia 1, and four non-FMDV serotypes belonging to three additional species ''Bovine rhinitis A virus'' (BRAV), ''Bovine rhinitis B virus'' (BRBV) and ''Equine rhinitis A virus'' (ERAV). Structure Aphthoviruses are non-enveloped and have an icosahedral capsid with a diameter of around 27 to 30 nm. The assembled viral capsid contains a single copy of the RNA genome and 60 copies of the four viral capsid proteins VP1, VP2, VP3, and VP4. The protomers form the sides of the icosahedral capsid. The VP4 protein is internal. Genome The aphthoviruses are differentiated from other picornaviruses as they have a larger genome (7.5–8.5 kilobases). The genome i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Friedrich Loeffler
Friedrich August Johannes Loeffler (; 24 June 18529 April 1915) was a German bacteriologist at the University of Greifswald. Biography He obtained his M.D. degree from the University of Berlin in 1874. He worked with Robert Koch from 1879 to 1884Isaac Asimov, ''Asimov's Biographical Encyclopedia of Science and Technology'', 2nd Revised edition as an assistant in the Imperial Health Office in Berlin. In 1884, he became staff physician at the Friedrich Wilhelm Institute in Berlin, and four years later became professor at the University of Greifswald. His development of original methods of staining rendered an important and lasting service to bacteriology. Early in his career, he began a study of parasitic diseases. Among his discoveries was the organism causing diphtheria (''Corynebacterium diphtheriae'') and the cause of foot-and-mouth disease (Aphthovirus). His description of the diphtheria bacillus, published in 1884, was the originating cause of an antitoxin treatment. He also c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wendell Stanley
Wendell Meredith Stanley (16 August 1904 – 15 June 1971) was an American biochemist, virologist and Nobel laureate. Biography Stanley was born in Ridgeville, Indiana, and earned a BSc in Chemistry at Earlham College in Richmond, Indiana. He then studied at the University of Illinois, gaining an MS in science in 1927 followed by a PhD in chemistry two years later. His later accomplishments include writing the book "Chemistry: A Beautiful Thing" and being a Pulitzer Prize nominee. Research As a member of National Research Council he moved temporarily for academic work with Heinrich Wieland in Munich before he returned to the States in 1931. On return he was approved as an assistant at The Rockefeller Institute for Medical Research. He remained with the Institute until 1948, becoming an Associate Member in 1937, and a Member in 1940. In 1948, he became Professor of Biochemistry at the University of California, Berkeley and built the Virus Laboratory and a free-standing De ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Germ Theory Of Disease
The germ theory of disease is the currently accepted scientific theory for many diseases. It states that microorganisms known as pathogens or "germs" can lead to disease. These small organisms, too small to be seen without magnification, invade humans, other animals, and other living hosts. Their growth and reproduction within their hosts can cause disease. "Germ" refers to not just a bacterium but to any type of microorganism, such as protists or fungi, or even non-living pathogens that can cause disease, such as viruses, prions, or viroids. Diseases caused by pathogens are called infectious diseases. Even when a pathogen is the principal cause of a disease, environmental and hereditary factors often influence the severity of the disease, and whether a potential host individual becomes infected when exposed to the pathogen. Pathogens are disease-carrying agents that can pass from one individual to another, both in humans and animals. Infectious diseases are caused by biological a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Toxin
A toxin is a naturally occurring organic poison produced by metabolic activities of living cells or organisms. Toxins occur especially as a protein or conjugated protein. The term toxin was first used by organic chemist Ludwig Brieger (1849–1919) and is derived from the word toxic. Toxins can be small molecules, peptides, or proteins that are capable of causing disease on contact with or absorption by body tissues interacting with biological macromolecules such as enzymes or cellular receptors. Toxins vary greatly in their toxicity, ranging from usually minor (such as a bee sting) to potentially fatal even at extremely low doses (such as botulinum toxin). Toxins are largely secondary metabolites, which are organic compounds that are not directly involved in an organism's growth, development, or reproduction, instead often aiding it in matters of defense. Terminology Toxins are often distinguished from other chemical agents strictly based on their biological origin. Le ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tobacco Mosaic Virus
''Tobacco mosaic virus'' (TMV) is a positive-sense single-stranded RNA virus species in the genus ''Tobamovirus'' that infects a wide range of plants, especially tobacco and other members of the family Solanaceae. The infection causes characteristic patterns, such as "mosaic"-like mottling and discoloration on the leaves (hence the name). TMV was the first virus to be discovered. Although it was known from the late 19th century that a non-bacterial infectious disease was damaging tobacco crops, it was not until 1930 that the infectious agent was determined to be a virus. It is the first pathogen identified as a virus. The virus was crystallised by W.M. Stanley. It has a similar size to the largest synthetic molecule, known as PG5 History In 1886, Adolf Mayer first described the tobacco mosaic disease that could be transferred between plants, similar to bacterial infections. In 1892, Dmitri Ivanovsky gave the first concrete evidence for the existence of a non-bacterial infect ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chamberland Filter
A Chamberland filter, also known as a Pasteur–Chamberland filter, is a porcelain water filter invented by Charles Chamberland in 1884. It was developed after Henry Doulton, Henry Doulton's ceramic water filter of 1827. It is similar to the Berkefeld filter in principle. Design The filter consists of a permeable unglazed porcelain tube (called bisque) that contains a ring of enameled porcelain through which the inflow pipe fits. The core of the porcelain is made up of a metal pipe with holes through which water flows out and is collected. Inflow is pressurized so filtration occurs under force. There are 13 types: ''L1'' to ''L13''. L1 filters have the coarsest pore size while L13 have the finest. Usefulness The Pasteur-Chamberland filter is as useful as other ceramic and porcelain filters. It is a good bacterial water filter used mainly as a high volume water filter.Textbook of Microbiology by Ananthanarayan and Panikar, The filter works more quickly when the water suppli ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Charles Chamberland
Charles Chamberland (; 12 March 1851 – 2 May 1908) was a French microbiologist from Chilly-le-Vignoble in the department of Jura who worked with Louis Pasteur. In 1884 he developed a type of filtration known today as the Chamberland filter or Chamberland-Pasteur filter, a device that made use of an unglazed porcelain bar. The filter had pores that were smaller than bacteria, thus making it possible to pass a solution containing bacteria through the filter, and having the bacteria completely removed from the solution. Chamberland was also credited for starting a research project that led to the invention of the autoclave An autoclave is a machine used to carry out industrial and scientific processes requiring elevated temperature and pressure in relation to ambient pressure and/or temperature. Autoclaves are used before surgical procedures to perform sterilizati ... device in 1879. References External links * Charles Edouard Chamberland and Louis Pasteur PasteurBre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microbiologist
A microbiologist (from Ancient Greek, Greek ) is a scientist who studies microscopic life forms and processes. This includes study of the growth, interactions and characteristics of Microorganism, microscopic organisms such as bacteria, algae, fungi, and some types of parasites and their vectors. Most microbiologists work in offices and/or research facilities, both in private biotechnology companies and in academia. Most microbiologists specialize in a given topic within microbiology such as bacteriology, parasitology, virology, or immunology. Duties Microbiologists generally work in some way to increase scientific knowledge or to utilise that knowledge in a way that improves outcomes in medicine or some industry. For many microbiologists, this work includes planning and conducting experimental research projects in some kind of laboratory setting. Others may have a more administrative role, supervising scientists and evaluating their results. Microbiologists working in the medi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rabies
Rabies is a viral disease that causes encephalitis in humans and other mammals. Early symptoms can include fever and tingling at the site of exposure. These symptoms are followed by one or more of the following symptoms: nausea, vomiting, violent movements, uncontrolled excitement, fear of water, an inability to move parts of the body, confusion, and loss of consciousness. Once symptoms appear, the result is virtually always death, regardless of treatment. The time period between contracting the disease and the start of symptoms is usually one to three months but can vary from less than one week to more than one year. The time depends on the distance the virus must travel along peripheral nerves to reach the central nervous system. Rabies is caused by lyssaviruses, including the rabies virus and Australian bat lyssavirus. It is spread when an infected animal bites or scratches a human or other animals. Saliva from an infected animal can also transmit rabies if the saliva come ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
