EIF3A

	EIF3A Eukaryotic translation initiation factor 3 subunit A (eIF3a) is a protein that in humans is encoded by the ''EIF3A'' gene. It is one of the subunits of Eukaryotic initiation factor 3 (eIF3) a multiprotein complex playing major roles in Eukaryotic_translation#Initiation, translation initiation in eukaryotes. Interactions EIF3A has been shown to Protein-protein interaction, interact with: * DISC1, * EIF3B, * EIF3C, * EIF3D, * EIF3EIP, * EIF3F, * EIF3G, * EIF3H, * EIF3I * EIF3J, * EIF3K, * EIF3S6, * EIF4B, * EIF4G2, and * FBXO32. See also Eukaryotic initiation factor 3, Eukaryotic initiation factor 3 (eIF3) References Further reading * * * * * * * * * * * {{gene-10-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	FBXO32 F-box only protein 32, also known as "MAFbx", for "Muscle Atrophy F-box gene", and "Atrogin-1," is a protein that in humans is encoded by the ''FBXO32'' gene. Function This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of mu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	EIF3G Eukaryotic translation initiation factor 3 subunit G (eIF3g) is a protein that in humans is encoded by the ''EIF3G'' gene. Interactions EIF3G has been shown to interact with Band 4.1, EIF3C and EIF3A Eukaryotic translation initiation factor 3 subunit A (eIF3a) is a protein that in humans is encoded by the ''EIF3A'' gene. It is one of the subunits of Eukaryotic initiation factor 3 (eIF3) a multiprotein complex playing major roles in translatio .... See also * Eukaryotic initiation factor 3 (eIF3) References Further reading * * * * * * * * * * * * {{Gene-19-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	EIF4G2 Eukaryotic translation initiation factor 4 gamma 2 (also called p97, NAT1, and DAP-5) is a protein that in humans is encoded by the ''EIF4G2'' gene. Function Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by the eIF4G2 gene shares similarity with the C-terminal region of eIF4G1 that contains the binding sites for eIF4A and eIF3. eIF4G2 additionally contains a binding site for eIF4E at the N-terminus. Unlike eIF4G1, which supports cap-dependent and independent translation, the eIF4G2 gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	EIF3S6 Eukaryotic translation initiation factor 3 subunit E (eIF3e) is a protein that in humans is encoded by the ''EIF3E'' gene. Interactions EIF3S6 has been shown to interact with: * BAT2, * COPS6 * CSN3, * EIF3A Eukaryotic translation initiation factor 3 subunit A (eIF3a) is a protein that in humans is encoded by the ''EIF3A'' gene. It is one of the subunits of Eukaryotic initiation factor 3 (eIF3) a multiprotein complex playing major roles in translatio ..., and * TRIM27. See also * Eukaryotic initiation factor 3 (eIF3) References Further reading * * * * * * * * * * * * * {{gene-8-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	EIF3K Eukaryotic translation initiation factor 3 subunit K (eIF3k) is a protein that in humans is encoded by the ''EIF3K'' gene. Function The ~800 kDa eukaryotic initiation factor 3 (eIF3) is the largest eIF and contains at least 12 subunits, including eIF3k/EIF2S12. eIF3 plays an essential role in translation by binding directly to the 40S ribosomal subunit and promoting formation of the 43S preinitiation complex. Interactions eIF3k has been shown to interact with Cyclin D3 and eIF3a Eukaryotic translation initiation factor 3 subunit A (eIF3a) is a protein that in humans is encoded by the ''EIF3A'' gene. It is one of the subunits of Eukaryotic initiation factor 3 (eIF3) a multiprotein complex playing major roles in Eukaryotic_ .... See also * Eukaryotic initiation factor 3 (eIF3) References Further reading * * * * External links * {{gene-19-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	EIF3J Eukaryotic translation initiation factor 3 subunit J (eIF3j) is a protein that in humans is encoded by the ''EIF3J'' gene. Interactions eIF3j has been shown to interact with eIF3a Eukaryotic translation initiation factor 3 subunit A (eIF3a) is a protein that in humans is encoded by the ''EIF3A'' gene. It is one of the subunits of Eukaryotic initiation factor 3 (eIF3) a multiprotein complex playing major roles in Eukaryotic_ .... See also * Eukaryotic initiation factor 3 (eIF3) References Further reading * * * * * * * * * External links * {{gene-15-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	EIF3I Eukaryotic translation initiation factor 3 subunit I (eIF3i) is a protein that in humans is encoded by the ''EIF3I'' gene. Interactions eIF3i has been shown to interact with TGF beta 1 and eIF3a Eukaryotic translation initiation factor 3 subunit A (eIF3a) is a protein that in humans is encoded by the ''EIF3A'' gene. It is one of the subunits of Eukaryotic initiation factor 3 (eIF3) a multiprotein complex playing major roles in Eukaryotic_ .... See also * Eukaryotic initiation factor 3 (eIF3) References Further reading * * * * * * * * * * * * * * * * {{gene-1-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	EIF3H Eukaryotic translation initiation factor 3 subunit H (eIF3h) is a protein that in humans is encoded by the ''EIF3H'' gene. Interactions eIF3h has been shown to interact with eIF3a Eukaryotic translation initiation factor 3 subunit A (eIF3a) is a protein that in humans is encoded by the ''EIF3A'' gene. It is one of the subunits of Eukaryotic initiation factor 3 (eIF3) a multiprotein complex playing major roles in translatio .... See also * Eukaryotic initiation factor 3 (eIF3) References Further reading * * * * * * * * * * * * External links * {{gene-8-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	EIF3F Eukaryotic translation initiation factor 3 subunit F (eIF3f) is a protein that in humans is encoded by the ''EIF3F'' gene. Interactions EIF3F has been shown to interact with Mammalian target of rapamycin and EIF3A Eukaryotic translation initiation factor 3 subunit A (eIF3a) is a protein that in humans is encoded by the ''EIF3A'' gene. It is one of the subunits of Eukaryotic initiation factor 3 (eIF3) a multiprotein complex playing major roles in translatio .... See also * Eukaryotic initiation factor 3 (eIF3) References Further reading * * * * * * * * * * * {{gene-11-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	EIF3EIP Eukaryotic translation initiation factor 3 subunit L (eIF3l), less commonly known as EIF3EIP, is a protein that in humans is encoded by the ''EIF3L'' gene. Interactions eIF3l has been shown to Protein-protein interaction, interact with EIF3A, eIF3a. See also Eukaryotic initiation factor 3, Eukaryotic initiation factor 3 (eIF3) References Further reading * * * * * * * * {{gene-22-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	EIF3D Eukaryotic translation initiation factor 3 subunit D (eIF3d) is a protein that in humans is encoded by the ''EIF3D'' gene. Function Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex. Interactions EIF3D has been shown to interact with PHLDA1 and EIF3A Eukaryotic translation initiation factor 3 subunit A (eIF3a) is a protein that in humans is encoded by the ''EIF3A'' gene. It is one of the subunits of Eukaryotic initiation factor 3 (eIF3) a multiprotein complex playing major roles in translatio .... ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	EIF3C Eukaryotic translation initiation factor 3 subunit C (eIF3c) is a protein that in humans is encoded by the ''EIF3C'' gene. Interactions EIF3C has been shown to interact with EIF3G and EIF3A Eukaryotic translation initiation factor 3 subunit A (eIF3a) is a protein that in humans is encoded by the ''EIF3A'' gene. It is one of the subunits of Eukaryotic initiation factor 3 (eIF3) a multiprotein complex playing major roles in Eukaryotic_ .... See also * Eukaryotic initiation factor 3 (eIF3) References Further reading * * * * * * * * * * * * * * * {{gene-16-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]