|
Dennie–Morgan Fold
A Dennie–Morgan fold, also known as a Dennie–Morgan line or an infraorbital fold, is a fold or line in the skin below the lower eyelid. It can simply be an ethnic/genetic trait, but was found in one study to occur in 25% of patients with atopic dermatitis. The presence of Dennie–Morgan folds can be used as a diagnostic marker for allergy, with a sensitivity of 78% and specificity of 76% for atopic dermatitis according to one study, although another study found them to be of diagnostic significance in atopic dermatitis. Such folds are also common among certain ethnic groups such as Africans, Tatars, Slavs, Balts and Finnic peoples, and are not known to be associated with any medical condition in these. The pathophysiology of this sign is not clear. One proposed mechanism is that continuous spasm of the superior tarsal muscle The superior tarsal muscle is a smooth muscle adjoining the levator palpebrae superioris muscle that helps to raise the upper eyelid. Structure T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eyelid
An eyelid is a thin fold of skin that covers and protects an eye. The levator palpebrae superioris muscle retracts the eyelid, exposing the cornea to the outside, giving vision. This can be either voluntarily or involuntarily. The human eyelid features a row of eyelashes along the eyelid margin, which serve to heighten the protection of the eye from dust and foreign debris, as well as from perspiration. "Palpebral" (and "blepharal") means relating to the eyelids. Its key function is to regularly spread the tears and other secretions on the eye surface to keep it moist, since the cornea must be continuously moist. They keep the eyes from drying out when asleep. Moreover, the blink reflex protects the eye from foreign bodies. The appearance of the human upper eyelid often varies between different populations. The prevalence of an epicanthic fold covering the inner corner of the eye account for the majority of East Asian and Southeast Asian populations, and is also found i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atopic Dermatitis
Atopic dermatitis (AD), also known as atopic eczema, is a long-term type of inflammation of the skin (dermatitis). It results in puritis, itchy, red, swollen, and cracked skin. Clear fluid may come from the affected areas, which often thickens over time. While the condition may occur at any age, it typically starts in childhood, with changing severity over the years. In children under one year of age, much of the body may be affected. As children get older, the areas on the insides of the knees and elbows are most commonly affected. In adults, the hands and feet are most commonly affected. Scratching the affected areas worsens the symptoms, and those affected have an increased risk of skin infections. Many people with atopic dermatitis develop hay fever or asthma. The cause is unknown but believed to involve genetics, immune system dysfunction, environmental exposures, and difficulties with the Semipermeable membrane, permeability of the skin. If one identical twin is affected, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diagnosis
Diagnosis is the identification of the nature and cause of a certain phenomenon. Diagnosis is used in many different disciplines, with variations in the use of logic, analytics, and experience, to determine " cause and effect". In systems engineering and computer science, it is typically used to determine the causes of symptoms, mitigations, and solutions. Computer science and networking * Bayesian networks * Complex event processing * Diagnosis (artificial intelligence) * Event correlation * Fault management * Fault tree analysis * Grey problem * RPR Problem Diagnosis * Remote diagnostics * Root cause analysis * Troubleshooting * Unified Diagnostic Services Mathematics and logic * Bayesian probability * Block Hackam's dictum * Occam's razor * Regression diagnostics * Sutton's law copy right remover block Medicine * Medical diagnosis * Molecular diagnostics Methods * CDR Computerized Assessment System * Computer-assisted diagnosis * Differential diagnosis * Medical di ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Allergy
Allergies, also known as allergic diseases, refer a number of conditions caused by the hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic dermatitis, allergic asthma, and anaphylaxis. Symptoms may include red eyes, an itchy rash, sneezing, coughing, a runny nose, shortness of breath, or swelling. Note: food intolerances and food poisoning are separate conditions. Common allergens include pollen and certain foods. Metals and other substances may also cause such problems. Food, insect stings, and medications are common causes of severe reactions. Their development is due to both genetic and environmental factors. The underlying mechanism involves immunoglobulin E antibodies (IgE), part of the body's immune system, binding to an allergen and then to a receptor on mast cells or basophils where it triggers the release of inflammatory chemicals such as histamine. Diagnosis is ty ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sensitivity And Specificity
''Sensitivity'' and ''specificity'' mathematically describe the accuracy of a test which reports the presence or absence of a condition. Individuals for which the condition is satisfied are considered "positive" and those for which it is not are considered "negative". *Sensitivity (true positive rate) refers to the probability of a positive test, conditioned on truly being positive. *Specificity (true negative rate) refers to the probability of a negative test, conditioned on truly being negative. If the true condition can not be known, a " gold standard test" is assumed to be correct. In a diagnostic test, sensitivity is a measure of how well a test can identify true positives and specificity is a measure of how well a test can identify true negatives. For all testing, both diagnostic and screening, there is usually a trade-off between sensitivity and specificity, such that higher sensitivities will mean lower specificities and vice versa. If the goal is to return the ratio at w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
African People
The population of Africa has grown rapidly over the past century and consequently shows a large youth bulge, further reinforced by a low life expectancy of below 50 years in some African countries. Total population as of 2020 is estimated at more than 1.3 billion, with a growth rate of more than 2.5% p.a. The total fertility rate (births per woman) for Sub-Saharan Africa is 4.7 as of 2018, the highest in the world according to the World Bank. The most populous African country is Nigeria with over 206 million inhabitants as of 2020 and a growth rate of 2.6% p.a. Population Genetics History Alternative Estimates of African Population, 0–1998 AD (in thousands) Source: Maddison and others. (University of Groningen). Shares of Africa and World Population, 0–2018 AD (% of world total) Source: Maddison and others (University of Groningen) and others. Vital Statistics 1950–2021AD Registration of vital events in most of Africa is incomplete. The website Our World in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tatars
The Tatars ()Tatar in the Collins English Dictionary is an umbrella term for different Turkic ethnic groups bearing the name "Tatar". Initially, the ethnonym ''Tatar'' possibly referred to the . That confederation was eventually incorporated into the when unified the various steppe tr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Slavs
Slavs are the largest European ethnolinguistic group. They speak the various Slavic languages, belonging to the larger Balto-Slavic branch of the Indo-European languages. Slavs are geographically distributed throughout northern Eurasia, mainly inhabiting Central and Eastern Europe, and the Balkans to the west; and Siberia to the east. A large Slavic minority is also scattered across the Baltic states and Central Asia, while a substantial Slavic diaspora is found throughout the Americas, as a result of immigration. Present-day Slavs are classified into East Slavs (chiefly Belarusians, Russians, Rusyns, and Ukrainians), West Slavs (chiefly Czechs, Kashubians, Poles, Slovaks and Sorbs) and South Slavs (chiefly Bosniaks, Bulgarians, Croats, Macedonians, Montenegrins, Serbs and Slovenes). The vast majority of Slavs are traditionally Christians. However, modern Slavic nations and ethnic groups are considerably diverse both genetically and culturally, and relations between them â ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Balts
The Balts or Baltic peoples ( lt, baltai, lv, balti) are an ethno-linguistic group of peoples who speak the Baltic languages of the Balto-Slavic branch of the Indo-European languages. One of the features of Baltic languages is the number of conservative or archaic features retained. Among the Baltic peoples are modern-day Lithuanians and Latvians (including Latgalians) — all Eastern Balts — as well as the Old Prussians, Yotvingians and Galindians — the Western Balts — whose languages and cultures are now extinct. Etymology Medieval German chronicler Adam of Bremen in the latter part of the 11th century AD was the first writer to use the term "Baltic" in reference to the sea of that name.Bojtár page 9. Before him various ancient places names, such as Balcia, were used in reference to a supposed island in the Baltic Sea. Adam, a speaker of German, connected ''Balt-'' with ''belt'', a word with which he was familiar. In Germanic languages there was some form of t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Finnic Peoples
The Finnic or Fennic peoples, sometimes simply called Finns, are the nations who speak languages traditionally classified in the Finnic (now commonly '' Finno-Permic'') language family, and which are thought to have originated in the region of the Volga River. The largest Finnic peoples by population are the Finns (or more precisely the Suomi, 6 million), the Estonians (1 million), the Mordvins (800,000), the Mari (570,000), the Udmurts (550,000), the Komis (330,000) and the Sami (100,000). The scope of the name "Finn" and "Finnic" varies by country. Today, Finnish and Estonian scholars restrict the term "Finnic" to the Baltic Finns, who include the Western Finns of Finland and their closest relatives but not the Sami. In Russia, however, where the Eastern Finns live, the word continues to be used in the broad sense, and sometimes implies the Volga Finns who have their own national republics. Three groups of people are covered by the names "Finn" and "Finnic" in the broad se ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Superior Tarsal Muscle
The superior tarsal muscle is a smooth muscle adjoining the levator palpebrae superioris muscle that helps to raise the upper eyelid. Structure The superior tarsal muscle originates on the underside of levator palpebrae superioris and inserts on the superior tarsal plate of the eyelid. Nerve supply The superior tarsal muscle receives its innervation from the sympathetic nervous system. Postganglionic sympathetic fibers originate in the superior cervical ganglion, and travel via the internal carotid plexus, where small branches communicate with the oculomotor nerve as it passes through the cavernous sinus. The sympathetic fibres continue to the superior division of the oculomotor nerve, where they enter the superior tarsal muscle on its inferior aspect. Function Its role is not fully clear, but may be an accessory muscle to raise the upper eyelid. Clinical significance Damage to some elements of the sympathetic nervous system can inhibit this muscle, causing a drooping ey ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Allergic Shiner
An allergic shiner is a dark discoloration below the eye that is associated with allergic rhinitis and often seen in conjunction with bilateral Dennie–Morgan folds. These shiners are caused by venous congestion within the infraorbital groove, particularly from the nose. The characteristic infraorbital discoloration related to allergic shiners is due to a backup in the venous network supplying the mucous membranes of the paranasal and nasal cavities draining primarily via the branches of the sphenopalatine veins passing backward to the pterygoid plexus. While a classic finding in pediatric patients with allergic rhinitis Allergic rhinitis, of which the seasonal type is called hay fever, is a type of inflammation in the nose that occurs when the immune system overreacts to allergens in the air. Signs and symptoms include a runny or stuffy nose, sneezing, red, i ..., these particular shiners will persist into adulthood if their allergies are not successfully addressed. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
