|
Dorothy M. Needham
Dorothy Mary Moyle Needham FRS (22 September 1896 – 22 December 1987) was an English biochemist known for her work on the biochemistry of muscle. She was married to biochemist Joseph Needham. Early life and education Dorothy Mary Moyle was born in London, to patent clerk John Thomas Moyle and his wife, Ellen Daves. She attended Claremont College, Stockport, an institution run by her aunt, Agnes Daves, and St Hilary's School, Alderley Edge, before entering Girton College, Cambridge. At Girton she became interested in chemistry, and biochemistry in particular after attending the lectures of Frederick Gowland Hopkins. After completing undergraduate studies in 1919, in which she obtained a 3rd Class Honours, she was offered a research position with Hopkins—one of the few scientific leaders at Cambridge at the time who offered research opportunities for women—at the Sir William Dunn Institute of Biochemistry, Cambridge, She earned a Master of Arts in 1923, and a PhD in 1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fellow Of The Royal Society
Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the judges of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural science, natural knowledge, including mathematics, engineering science, and medical science". Fellow, Fellowship of the Society, the oldest known scientific academy in continuous existence, is a significant honour. It has been awarded to many eminent scientists throughout history, including Isaac Newton (1672), Michael Faraday (1824), Charles Darwin (1839), Ernest Rutherford (1903), Srinivasa Ramanujan (1918), Albert Einstein (1921), Paul Dirac (1930), Winston Churchill (1941), Subrahmanyan Chandrasekhar (1944), Dorothy Hodgkin (1947), Alan Turing (1951), Lise Meitner (1955) and Francis Crick (1959). More recently, fellowship has been awarded to Stephen Hawking (1974), David Attenborough (1983), Tim Hunt (1991), Elizabeth Blackburn (1992), Tim Berners-Lee (2001), Venki R ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fumaric Acid
Fumaric acid is an organic compound with the formula HO2CCH=CHCO2H. A white solid, fumaric acid occurs widely in nature. It has a fruit-like taste and has been used as a food additive. Its E number is E297. The salts and esters are known as fumarates. Fumarate can also refer to the ion (in solution). Fumaric acid is the trans isomer of butenedioic acid, while maleic acid is the cis isomer. Biosynthesis and occurrence It is produced in eukaryotic organisms from succinate in complex 2 of the electron transport chain via the enzyme succinate dehydrogenase. It is one of two isomeric unsaturated dicarboxylic acids, the other being maleic acid. In fumaric acid the carboxylic acid groups are ''trans'' (''E'') and in maleic acid they are ''cis'' (''Z''). Fumaric acid is found in fumitory (''Fumaria officinalis''), bolete mushrooms (specifically ''Boletus fomentarius var. pseudo-igniarius''), lichen, and Iceland moss. Fumarate is an intermediate in the citric acid cycle used b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Royal Society
The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, recognising excellence in science, supporting outstanding science, providing scientific advice for policy, education and public engagement and fostering international and global co-operation. Founded on 28 November 1660, it was granted a royal charter by King Charles II as The Royal Society and is the oldest continuously existing scientific academy in the world. The society is governed by its Council, which is chaired by the Society's President, according to a set of statutes and standing orders. The members of Council and the President are elected from and by its Fellows, the basic members of the society, who are themselves elected by existing Fellows. , there are about 1,700 fellows, allowed to use the postnominal title FRS (Fellow of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gonville And Caius College, Cambridge
Gonville and Caius College, often referred to simply as Caius ( ), is a constituent college of the University of Cambridge in Cambridge, England. Founded in 1348, it is the fourth-oldest of the University of Cambridge's 31 colleges and one of the wealthiest. The college has been attended by many students who have gone on to significant accomplishment, including fifteen Nobel Prize winners, the second-highest of any Oxbridge college after Trinity College, Cambridge. The college has long historical associations with the teaching of medicine, especially due to its prominent alumni in the medical profession. It also has globally-recognized and prestigious academic programmes in law, economics, English literature, and history. Famous Gonville and Caius alumni include physicians John Caius (who gave the college the caduceus in its insignia) and William Harvey. Other alumni in the sciences include Francis Crick (joint discoverer of the structure of DNA with James Watson), James Ch ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lucy Cavendish College, Cambridge
Lucy Cavendish College is a Colleges of the University of Cambridge, constituent college of the University of Cambridge. The college is named in honour of Lucy Cavendish (1841–1925), who campaigned for the reform of women's education. History The college was founded in 1965 by female academics of the University of Cambridge who believed that the university offered too few and too restricted opportunities for women as either students or academics. Its origins are traceable to the ''Society of Women Members of the Regent House who are not Fellows of Colleges'' (informally known as the Dining Group) which in the 1950s sought to provide the benefits of collegiality to its members who, being female, were not college fellows. At the time there were only two women's colleges in Cambridge, Girton College, Cambridge, Girton and Newnham College, Cambridge, Newnham, insufficient for the large and growing numbers of female academic staff in the university. The college was named in hono ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Doctor Of Science
Doctor of Science ( la, links=no, Scientiae Doctor), usually abbreviated Sc.D., D.Sc., S.D., or D.S., is an academic research degree awarded in a number of countries throughout the world. In some countries, "Doctor of Science" is the degree used for the standard doctorate in the sciences; elsewhere the Sc.D. is a "higher doctorate" awarded in recognition of a substantial and sustained contribution to scientific knowledge beyond that required for a Doctor of Philosophy (PhD). Africa Algeria and Morocco In Algeria, Morocco, Libya and Tunisia, all universities accredited by the state award a "Doctorate" in all fields of science and humanities, equivalent to a PhD in the United Kingdom or United States. Some universities in these four Arab countries award a "Doctorate of the State" in some fields of study and science. A "Doctorate of the State" is slightly higher in esteem than a regular doctorate, and is awarded after performing additional in-depth post-doctorate research or ach ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chongqing
Chongqing ( or ; ; Sichuanese dialects, Sichuanese pronunciation: , Standard Mandarin pronunciation: ), Postal Romanization, alternately romanized as Chungking (), is a Direct-administered municipalities of China, municipality in Southwest China. The official abbreviation of the city, "" (), was approved by the State Council of the People's Republic of China, State Council on 18 April 1997. This abbreviation is derived from the old name of a part of the Jialing River that runs through Chongqing and feeds into the Yangtze River. Administratively, it is one of the four municipalities under the direct administration of the Government of China, central government of the People's Republic of China (the other three are Beijing, Shanghai, and Tianjin), and the only such municipality located deep inland. The municipality of Chongqing, roughly the size of Austria, includes the city of Chongqing as well as various discontiguous cities. Due to a classification technicality, Chongqing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mustard Gas
Mustard gas or sulfur mustard is a chemical compound belonging to a family of cytotoxic and blister agents known as mustard agents. The name ''mustard gas'' is technically incorrect: the substance, when dispersed, is often not actually a gas, but is instead in the form of a fine mist of liquid droplets.https://www.acs.org/content/dam/acsorg/education/resources/highschool/chemmatters/gc-mustard-gas-personal-safety-and-natl-security.pdf Mustard gases form blisters on exposed skin and in the lungs, often resulting in prolonged illness ending in death. The active ingredient in typical mustard gas is the organosulfur compound bis(2-chloroethyl) sulfide. In the wider sense, compounds with the structural element are known as ''sulfur mustards'' and ''nitrogen mustards'', respectively. Such compounds are potent alkylating agents, which can interfere with several biological processes. History as chemical weapons As a chemical weapon, mustard gas was first used in World War I, and has ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ministry Of Supply
The Ministry of Supply (MoS) was a department of the UK government formed in 1939 to co-ordinate the supply of equipment to all three British armed forces, headed by the Minister of Supply. A separate ministry, however, was responsible for aircraft production, and the Admiralty retained responsibilities for supplying the Royal Navy.Hornby (1958) During the war years the MoS was based at Shell Mex House in The Strand, London. The Ministry of Supply also took over all army research establishments in 1939. The Ministry of Aircraft Production was abolished in 1946, and the MoS took over its responsibilities for aircraft, including the associated research establishments. In the same year, it also took on increased responsibilities for atomic weapons, including the H-bomb development programme. The Ministry of Supply was abolished in late 1959 and its responsibilities passed to the Ministry of Aviation, the War Office, and the Air Ministry. The latter two ministries were subsequently ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Malcolm Dixon
Malcolm Dixon (18 April 1899 – 7 December 1985) was a British biochemist. Education and early life Dixon was born in Cambridge, UK to Allick Page Dixon and Caroline Dewe Dixon (née Mathews). He received his PhD in 1925, for research supervised by Frederick Gowland Hopkins at the University of Cambridge. Research and career Dixon's research investigated the purification of enzymes and the enzyme kinetics of enzyme-catalyzed reactions. He studied the oxidation of glutathione and other thiols by molecular oxygen and measured the redox potential of the thiol-disulfide system, also establishing that the oxidation of glutathione was catalyzed by trace metals. He investigated xanthine oxidase, and thereby elucidated many aspects of the chemistry of dehydrogenases. He showed that the hydrogen peroxide formed in the reaction of xanthine oxidase with molecular oxygen inactivated the enzyme and that the inhibition could be relieved by the addition of catalase, thus helping to establish ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ATPase
ATPases (, Adenosine 5'-TriPhosphatase, adenylpyrophosphatase, ATP monophosphatase, triphosphatase, SV40 T-antigen, ATP hydrolase, complex V (mitochondrial electron transport), (Ca2+ + Mg2+)-ATPase, HCO3−-ATPase, adenosine triphosphatase) are a class of enzymes that catalyze the decomposition of ATP into ADP and a free phosphate ion or the inverse reaction. This dephosphorylation reaction releases energy, which the enzyme (in most cases) harnesses to drive other chemical reactions that would not otherwise occur. This process is widely used in all known forms of life. Some such enzymes are integral membrane proteins (anchored within biological membranes), and move solutes across the membrane, typically against their concentration gradient. These are called transmembrane ATPases. Functions Transmembrane ATPases import metabolites necessary for cell metabolism and export toxins, wastes, and solutes that can hinder cellular processes. An important example is the sodium-potass ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Myosin
Myosins () are a superfamily of motor proteins best known for their roles in muscle contraction and in a wide range of other motility processes in eukaryotes. They are ATP-dependent and responsible for actin-based motility. The first myosin (M2) to be discovered was in 1864 by Wilhelm Kühne. Kühne had extracted a viscous protein from skeletal muscle that he held responsible for keeping the tension state in muscle. He called this protein ''myosin''. The term has been extended to include a group of similar ATPases found in the cells of both striated muscle tissue and smooth muscle tissue. Following the discovery in 1973 of enzymes with myosin-like function in '' Acanthamoeba castellanii'', a global range of divergent myosin genes have been discovered throughout the realm of eukaryotes. Although myosin was originally thought to be restricted to muscle cells (hence '' myo-''(s) + '' -in''), there is no single "myosin"; rather it is a very large superfamily of genes whose p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
