Dorothy J. Phillips
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Dorothy J. Phillips
Dorothy Jean Phillips (née Wingfield) (born July 27, 1945) is an American chemist and president-elect of the American Chemical Society. She worked on circular dichroism and bioseparation. In 1967 Phillips was the first African-American woman to complete a bachelor's degree at Vanderbilt University. Early life and education Phillips grew up in segregation in the southern United States. She was one of eight children. Her father, Reverend Robert Cam Wingfield, worked as a porter for the Greyhound Bus station before attending classes at the American Baptist Theological Seminary to become a Baptist minister. Her mother, Rebecca Cooper Wingfield, did occasional domestic work. As a young girl the only white people Phillips knew were those who had employed her mother. Her parents were very supportive of her education, and attended local meetings of the ''Negro'' Parent Teachers Association. The Wingfields became more active with the civil rights movement after the Rosa Parks bu ...
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Nashville
Nashville is the capital city of the U.S. state of Tennessee and the seat of Davidson County. With a population of 689,447 at the 2020 U.S. census, Nashville is the most populous city in the state, 21st most-populous city in the U.S., and the fourth most populous city in the southeastern U.S. Located on the Cumberland River, the city is the center of the Nashville metropolitan area, which is one of the fastest growing in the nation. Named for Francis Nash, a general of the Continental Army during the American Revolutionary War, the city was founded in 1779. The city grew quickly due to its strategic location as a port on the Cumberland River and, in the 19th century, a railroad center. Nashville seceded with Tennessee during the American Civil War; in 1862 it was the first state capital in the Confederacy to be taken by Union forces. After the war, the city reclaimed its position and developed a manufacturing base. Since 1963, Nashville has had a consolidated city-county gov ...
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Alpha Kappa Alpha
Alpha Kappa Alpha Sorority, Inc. () is the first intercollegiate historically African American sorority. The sorority was founded on January 15, 1908, at the historically black Howard University in Washington, D.C., by a group of sixteen students led by Ethel Hedgeman Lyle. Forming a sorority broke barriers for African-American women in areas where they had little power or authority due to a lack of opportunities for minorities and women in the early 20th century. Alpha Kappa Alpha was incorporated on January 29, 1913. The sorority is one of the nation's largest Greek-letter organizations, having had more than 300,000 members in 1,024 chapters in the United States and several other countries. Women may join through undergraduate chapters at a college or university, or they may be invited to join by a graduate chapter after acquiring an undergraduate or advanced college degree. Alpha Kappa Alpha is part of the National Pan-Hellenic Council (NPHC). The current International Pr ...
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New England
New England is a region comprising six states in the Northeastern United States: Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island, and Vermont. It is bordered by the state of New York to the west and by the Canadian provinces of New Brunswick to the northeast and Quebec to the north. The Atlantic Ocean is to the east and southeast, and Long Island Sound is to the southwest. Boston is New England's largest city, as well as the capital of Massachusetts. Greater Boston is the largest metropolitan area, with nearly a third of New England's population; this area includes Worcester, Massachusetts (the second-largest city in New England), Manchester, New Hampshire (the largest city in New Hampshire), and Providence, Rhode Island (the capital of and largest city in Rhode Island). In 1620, the Pilgrims, Puritan Separatists from England, established Plymouth Colony, the second successful English settlement in America, following the Jamestown Settlement in Virginia foun ...
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Sildenafil
Sildenafil, sold under the brand name Viagra, among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. It is unclear if it is effective for treating sexual dysfunction in women. It is taken by mouth or by injection into a vein. Onset is typically within twenty minutes and lasts for about two hours. Common side effects include headaches, heartburn, and flushed skin. Caution is advised in those with cardiovascular disease. Rare but serious side effects include a prolonged erection (priapism) that can lead to damage to the penis, vision problems, and hearing loss. Sildenafil should not be taken by people on nitrates such as nitroglycerin (glycerin trinitrate), as this may result in a serious drop in blood pressure. Sildenafil should not be taken within four hours of taking an alpha blocker. Sildenafil acts by blocking phosphodiesterase 5 (PDE5), an enzyme that promotes breakdown of cGMP, which regulates blood flow in the pe ...
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High-performance Liquid Chromatography
High-performance liquid chromatography (HPLC), formerly referred to as high-pressure liquid chromatography, is a technique in analytical chemistry used to separate, identify, and quantify each component in a mixture. It relies on pumps to pass a pressurized liquid solvent containing the sample mixture through a column filled with a solid adsorbent material. Each component in the sample interacts slightly differently with the adsorbent material, causing different flow rates for the different components and leading to the separation of the components as they flow out of the column. HPLC has been used for manufacturing (''e.g.'', during the production process of pharmaceutical and biological products), legal (''e.g.'', detecting performance enhancement drugs in urine), research (''e.g.'', separating the components of a complex biological sample, or of similar synthetic chemicals from each other), and medical (''e.g.'', detecting vitamin D levels in blood serum) purposes. Chrom ...
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Millipore Corp
Millipore may refer to: *Millipore Corporation, a biosciences company *Millipore filter, a nucleopore filter A nuclepore filter (brand name Nuclepore from Whatman, part of GE Healthcare) is a kind of filter in which holes a few micrometres in size have been created in a plastic (e.g. polycarbonate) membrane. These filters are generally created by exposing ..., nitrocellulose or polycarbonate membrane filter with a pore size 0.2 μm up to 20 µm * Millipore chamber, or Millipore Diffusion chamber, a round-shaped chamber widely used for ''in vivo'' research, sealed at each end with a cellulose cell-impenetrable filter to permit the growth of transplanted cells or tissue, while allowing nutrients through {{disambiguation ...
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Chromatography
In chemical analysis, chromatography is a laboratory technique for the separation of a mixture into its components. The mixture is dissolved in a fluid solvent (gas or liquid) called the ''mobile phase'', which carries it through a system (a column, a capillary tube, a plate, or a sheet) on which a material called the ''stationary phase'' is fixed. Because the different constituents of the mixture tend to have different affinities for the stationary phase and are retained for different lengths of time depending on their interactions with its surface sites, the constituents travel at different apparent velocities in the mobile fluid, causing them to separate. The separation is based on the differential partitioning between the mobile and the stationary phases. Subtle differences in a compound's partition coefficient result in differential retention on the stationary phase and thus affect the separation. Chromatography may be preparative or analytical. The purpose of preparativ ...
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Michigan State University
Michigan State University (Michigan State, MSU) is a public university, public Land-grant university, land-grant research university in East Lansing, Michigan. It was founded in 1855 as the Agricultural College of the State of Michigan, the first of its kind in the United States. It is considered a Public Ivy, or a public institution which offers an academic experience similar to that of an Ivy League university. After the introduction of the Morrill Land-Grant Acts, Morrill Act in 1862, the state designated the college a land-grant institution in 1863, making it the first of the land-grant colleges in the United States. The college became coeducational in 1870. In 1955, the state officially made the college a university, and the current name, Michigan State University, was adopted in 1964. Today, Michigan State has the largest undergraduate enrollment among Michigan's colleges and universities and approximately 634,300 living alums worldwide. The university is a member of the ...
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Electron Paramagnetic Resonance
Electron paramagnetic resonance (EPR) or electron spin resonance (ESR) spectroscopy is a method for studying materials that have unpaired electrons. The basic concepts of EPR are analogous to those of nuclear magnetic resonance (NMR), but the spins excited are those of the electrons instead of the atomic nuclei. EPR spectroscopy is particularly useful for studying metal complexes and organic radicals. EPR was first observed in Kazan State University by Soviet physicist Yevgeny Zavoisky in 1944, and was developed independently at the same time by Brebis Bleaney at the University of Oxford. Theory Origin of an EPR signal Every electron has a magnetic moment and spin quantum number s = \tfrac , with magnetic components m_\mathrm = + \tfrac or m_\mathrm = - \tfrac . In the presence of an external magnetic field with strength B_\mathrm , the electron's magnetic moment aligns itself either antiparallel ( m_\mathrm = - \tfrac ) or parallel ( m_\mathrm = + \tfrac ) to the fie ...
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Biochemistry
Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and metabolism. Over the last decades of the 20th century, biochemistry has become successful at explaining living processes through these three disciplines. Almost all areas of the life sciences are being uncovered and developed through biochemical methodology and research. Voet (2005), p. 3. Biochemistry focuses on understanding the chemical basis which allows biological molecules to give rise to the processes that occur within living cells and between cells,Karp (2009), p. 2. in turn relating greatly to the understanding of tissues and organs, as well as organism structure and function.Miller (2012). p. 62. Biochemistry is closely related to molecular biology, which is the study of the molecular mechanisms of biological phenomena.As ...
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