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Digit Ratio
The digit ratio is the ratio of the lengths of different digits or fingers on a hand, the study of which has been considered pseudoscience. The 2D:4D ratio is the most studied digit ratio and is calculated by dividing the length of the index finger of a given hand by the length of the ring finger of the same hand. Although studies have claimed to show a correlation between the 2D:4D digit ratio and various physical and behavioral traits, these studies have drawn criticism for irreproducible or contradictory findings, exaggerated claims of usefulness, and lack of high quality research protocols. Measurement The digit length is typically measured on the palmar (ventral, "front", "palm-side") hand, from the midpoint of the bottom crease to the tip of the finger. Measurement of the digits on the dorsal ("back-side") hand, from the tip of the finger to the proximal phalange-bone protrusion (which occurs when digits are bent at 90 degrees to the palm), has recently also gained ...
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Benford's Law
Benford's law, also known as the Newcomb–Benford law, the law of anomalous numbers, or the first-digit law, is an observation that in many real-life sets of numerical data, the leading digit is likely to be small.Arno Berger and Theodore P. HillBenford's Law Strikes Back: No Simple Explanation in Sight for Mathematical Gem 2011. In sets that obey the law, the number 1 appears as the leading significant digit about 30% of the time, while 9 appears as the leading significant digit less than 5% of the time. If the digits were distributed uniformly, they would each occur about 11.1% of the time. Benford's law also makes predictions about the distribution of second digits, third digits, digit combinations, and so on. The graph to the right shows Benford's law for base 10, one of infinitely many cases of a generalized law regarding numbers expressed in arbitrary (integer) bases, which rules out the possibility that the phenomenon might be an artifact of the base-10 number syste ...
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Estradiol
Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone. It is involved in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is responsible for the development of female secondary sexual characteristics such as the breasts, widening of the hips and a female-associated pattern of fat distribution. It is also important in the development and maintenance of female reproductive tissues such as the mammary glands, uterus and vagina during puberty, adulthood and pregnancy. It also has important effects in many other tissues including bone, fat, skin, liver, and the brain. Though estradiol levels in males are much lower than in females, estradiol has important roles in males as well. Apart from humans and other mammals, estradiol is also found in most vertebrates and crustaceans, insects, fish, and other animal species. Estradiol is produced especially within the follicles of the ovaries, but also in o ...
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COVID-19
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first known case was COVID-19 pandemic in Hubei, identified in Wuhan, China, in December 2019. The disease quickly spread worldwide, resulting in the COVID-19 pandemic. The symptoms of COVID‑19 are variable but often include fever, cough, headache, fatigue, breathing difficulties, Anosmia, loss of smell, and Ageusia, loss of taste. Symptoms may begin one to fourteen days incubation period, after exposure to the virus. At least a third of people who are infected Asymptomatic, do not develop noticeable symptoms. Of those who develop symptoms noticeable enough to be classified as patients, most (81%) develop mild to moderate symptoms (up to mild pneumonia), while 14% develop severe symptoms (dyspnea, Hypoxia (medical), hypoxia, or more than 50% lung involvement on imaging), and 5% develop critical symptoms (respiratory failure ...
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Case Fatality Rate
In epidemiology, case fatality rate (CFR) – or sometimes more accurately case-fatality risk – is the proportion of people diagnosed with a certain disease, who end up dying of it. Unlike a disease's mortality rate, the CFR does not take into account the time period between disease onset and death. A CFR is generally expressed as a percentage. It represents a measure of disease lethality and may change with different treatments. CFRs are most often used for with discrete, limited-time courses, such as acute infections. Terminology The ''mortality rate''  –  often confused with the CFR  –  is a measure of the relative number of deaths (either in general, or due to a specific cause) within the entire population per unit of time. A CFR, in contrast, is the number of deaths among the number of diagnosed cases only, regardless of time or total population. From a mathematical point of view, by taking values between 0 and 1 or 0% and 100%, CFRs are actually a measure o ...
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Dizygotic Twins
Twins are two offspring produced by the same pregnancy.MedicineNet > Definition of TwinLast Editorial Review: 19 June 2000 Twins can be either ''monozygotic'' ('identical'), meaning that they develop from one zygote, which splits and forms two embryos, or ''dizygotic'' ('non-identical' or 'fraternal'), meaning that each twin develops from a separate egg and each egg is fertilized by its own sperm cell. Since identical twins develop from one zygote, they will share the same sex, while fraternal twins may or may not. In rare cases twins can have the same mother and different fathers (heteropaternal superfecundation). In contrast, a fetus that develops alone in the womb (the much more common case, in humans) is called a ''singleton'', and the general term for one offspring of a multiple birth is a ''multiple''. Unrelated look-alikes whose resemblance parallels that of twins are referred to as doppelgängers. Statistics The human twin birth rate in the United States rose 76% from ...
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Allometric
Allometry is the study of the relationship of body size to shape, anatomy, physiology and finally behaviour, first outlined by Otto Snell in 1892, by D'Arcy Thompson in 1917 in ''On Growth and Form'' and by Julian Huxley in 1932. Overview Allometry is a well-known study, particularly in statistical shape analysis for its theoretical developments, as well as in biology for practical applications to the differential growth rates of the parts of a living organism's body. One application is in the study of various insect species (e.g., Hercules beetles), where a small change in overall body size can lead to an enormous and disproportionate increase in the dimensions of appendages such as legs, antennae, or horns The relationship between the two measured quantities is often expressed as a power law equation (Allometric equation) which expresses a remarkable scale symmetry: : y = kx^a \,\! or in a logarithmic form: : \log y = a \log x + \log k\,\! or similarly \ln y = a \ln x ...
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Biology Letters
''Biology Letters'' is a peer-reviewed, biological, scientific journal published by the Royal Society. It focuses on the rapid publication of short high quality research articles, reviews and opinion pieces across the biological sciences. ''Biology Letters'' has an average turnaround time of twenty four days from submission to a first decision. The editor-in-chief is Professor David Beerling FRS (University of Sheffield) who is supported by an international Editorial Board of practising scientists. Contents and themes As well as the conventional, short research articles, ''Biology Letters'' has recently published Special Features and Mini Series. While Special Features are a collection of up to 20 articles on a specific theme and published across multiple issues, Mini Series include up to six articles that are published in one issue. Examples of topics in these formats include ocean acidification, fossils, extinction, enhanced rock weathering and the evolutionary ecology of sp ...
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Cave Painting
In archaeology, Cave paintings are a type of parietal art (which category also includes petroglyphs, or engravings), found on the wall or ceilings of caves. The term usually implies prehistoric origin, and the oldest known are more than 40,000 years old (art of the Upper Paleolithic), found in the caves in the district of Maros ( Sulawesi, Indonesia). The oldest are often constructed from hand stencils and simple geometric shapes.M. Aubert et al., "Pleistocene cave art from Sulawesi, Indonesia", ''Nature'' volume 514, pages 223–227 (09 October 2014). "using uranium-series dating of coralloid speleothems directly associated with 12 human hand stencils and two figurative animal depictions from seven cave sites in the Maros karsts of Sulawesi, we show that rock art traditions on this Indonesian island are at least compatible in age with the oldest European art. The earliest dated image from Maros, with a minimum age of 39.9 kyr, is now the oldest known hand stencil in the world. In ...
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Hand Stencil
In archaeology, Cave paintings are a type of parietal art (which category also includes petroglyphs, or engravings), found on the wall or ceilings of caves. The term usually implies prehistoric origin, and the oldest known are more than 40,000 years old (art of the Upper Paleolithic), found in the caves in the district of Maros ( Sulawesi, Indonesia). The oldest are often constructed from hand stencils and simple geometric shapes.M. Aubert et al., "Pleistocene cave art from Sulawesi, Indonesia", ''Nature'' volume 514, pages 223–227 (09 October 2014). "using uranium-series dating of coralloid speleothems directly associated with 12 human hand stencils and two figurative animal depictions from seven cave sites in the Maros karsts of Sulawesi, we show that rock art traditions on this Indonesian island are at least compatible in age with the oldest European art. The earliest dated image from Maros, with a minimum age of 39.9 kyr, is now the oldest known hand stencil in the world. In ...
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King's College London
King's College London (informally King's or KCL) is a public research university located in London, England. King's was established by royal charter in 1829 under the patronage of King George IV and the Duke of Wellington. In 1836, King's became one of the two founding colleges of the University of London. It is one of the oldest university-level institutions in England. In the late 20th century, King's grew through a series of mergers, including with Queen Elizabeth College and Chelsea College of Science and Technology (in 1985), the Institute of Psychiatry (in 1997), the United Medical and Dental Schools of Guy's and St Thomas' Hospitals and the Florence Nightingale School of Nursing and Midwifery (in 1998). King's has five campuses: its historic Strand Campus in central London, three other Thames-side campuses (Guy's, St Thomas' and Waterloo) nearby and one in Denmark Hill in south London. It also has a presence in Shrivenham, Oxfordshire, for its professional mi ...
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Glenn Wilson (psychologist)
Glenn Daniel Wilson (born 29 December 1942) is a psychologist best known for his work on attitude and personality measurement, sexual attraction, deviation and dysfunction, partner compatibility, and psychology applied to performing arts. In 2001, Wilson was ranked among the 10 most frequently cited British psychologists in scientific journals. He is a fellow of the British Psychological Society and makes frequent media appearances as a psychology expert, especially in TV news and documentaries. Biography After graduating MA at the University of Canterbury, Christchurch, Wilson moved to London in 1967 to study for his PhD under the supervision of Hans Eysenck, with whom he subsequently collaborated on a number of research projects and co-authored six books. He also co-authored the ''Eysenck Personality Profiler'', a standard personality test used in clinical research and industry. With John Patterson, he devised the ''Wilson–Patterson Conservatism Scale'', which has been wi ...
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Estrogen Receptor Alpha
Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor (mainly found as a chromatin-binding protein) that is activated by the sex hormone estrogen. In humans, ERα is encoded by the gene ''ESR1'' (EStrogen Receptor 1). Structure The estrogen receptor (ER) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. Alternative splicing results in several ESR1 mRNA transcripts, which differ primarily in their 5-prime untranslated regions. The translated receptors show less variability. Ligands Agonists Non-selective * Endogenous estrogens (e.g., estradiol, estrone, estriol, estetrol) * Natural estrogens (e.g., conjugated equine estrogens) * Synthetic estrogens (e.g., ethinylestradiol, diethylstilbestrol) Selective Agonists of ERα selective over ERβ include: * Propylp ...
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