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Diego Krapf
Diego Krapf (born November 21, 1973) is an Argentine-Israeli-American physicist known for his work on anomalous diffusion and ergodicity breaking. He currently is a professor in the Department of Electrical and Computer Engineering at Colorado State University. Early life and education Diego Krapf was born on November 21, 1973, to Martha Elbert and Luis Krapf. He spent his childhood growing up in Rosario, Argentina, and he attended the Instituto Politécnico Superior. In 1992, after finishing high school, Krapf immigrated to Israel, where he spent half a year in Kibbutz Gan Shmuel and then moved to Jerusalem. He enrolled in physics at the Hebrew University of Jerusalem. Krapf holds a BSc in physics (1997), a MSc in applied physics (2000) and a PhD in applied physics (2004) from the Hebrew University of Jerusalem. After finishing his PhD, he completed a postdoc at the Delft University of Technology (2007), doing research in nanoelectrode fabrication and single molecule exper ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rosario, Argentina
Rosario () is the largest city in the central Argentine province of Santa Fe. The city is located northwest of Buenos Aires, on the west bank of the Paraná River. Rosario is the third-most populous city in the country, and is also the most populous city in Argentina that is not a capital (provincial or national). With a growing and important metropolitan area, Greater Rosario has an estimated population of 1,750,000 . One of its main attractions includes the neoclassical, Art Nouveau, and Art Deco architecture that has been retained over the centuries in hundreds of residences, houses and public buildings. Rosario is the head city of the Rosario Department and is located at the heart of the major industrial corridor in Argentina. The city is a major railroad terminal and the shipping center for north-eastern Argentina. Ships reach the city via the Paraná River, which allows the existence of a port. The Port of Rosario is subject to silting and must be dredged periodically. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nanopore
A nanopore is a pore of nanometer size. It may, for example, be created by a pore-forming protein or as a hole in synthetic materials such as silicon or graphene. When a nanopore is present in an electrically insulating membrane, it can be used as a single-molecule detector. It can be a biological protein channel in a high electrical resistance lipid bilayer, a pore in a solid-state membrane or a hybrid of these – a protein channel set in a synthetic membrane. The detection principle is based on monitoring the ionic current passing through the nanopore as a voltage is applied across the membrane. When the nanopore is of molecular dimensions, passage of molecules (e.g., DNA) cause interruptions of the "open" current level, leading to a "translocation event" signal. The passage of RNA or single-stranded DNA molecules through the membrane-embedded alpha-hemolysin channel (1.5 nm diameter), for example, causes a ~90% blockage of the current (measured at 1 M KCl solution). It m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flagellum
A flagellum (; ) is a hairlike appendage that protrudes from certain plant and animal sperm cells, and from a wide range of microorganisms to provide motility. Many protists with flagella are termed as flagellates. A microorganism may have from one to many flagella. A gram-negative bacterium ''Helicobacter pylori'' for example uses its multiple flagella to propel itself through the mucus lining to reach the stomach epithelium, where it may cause a gastric ulcer to develop. In some bacteria the flagellum can also function as a sensory organelle, being sensitive to wetness outside the cell. Across the three domains of Bacteria, Archaea, and Eukaryota the flagellum has a different structure, protein composition, and mechanism of propulsion but shares the same function of providing motility. The Latin word means " whip" to describe its lash-like swimming motion. The flagellum in archaea is called the archaellum to note its difference from the bacterial flagellum. Eukaryotic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sperm
Sperm is the male reproductive cell, or gamete, in anisogamous forms of sexual reproduction (forms in which there is a larger, female reproductive cell and a smaller, male one). Animals produce motile sperm with a tail known as a flagellum, which are known as spermatozoa, while some red algae and fungi produce non-motile sperm cells, known as spermatia. Flowering plants contain non-motile sperm inside pollen, while some more basal plants like ferns and some gymnosperms have motile sperm. Sperm cells form during the process known as spermatogenesis, which in amniotes ( reptiles and mammals) takes place in the seminiferous tubules of the testes. This process involves the production of several successive sperm cell precursors, starting with spermatogonia, which differentiate into spermatocytes. The spermatocytes then undergo meiosis, reducing their chromosome number by half, which produces spermatids. The spermatids then mature and, in animals, construct a tail, or flagellum, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cytoskeleton
The cytoskeleton is a complex, dynamic network of interlinking protein filaments present in the cytoplasm of all cells, including those of bacteria and archaea. In eukaryotes, it extends from the cell nucleus to the cell membrane and is composed of similar proteins in the various organisms. It is composed of three main components, microfilaments, intermediate filaments and microtubules, and these are all capable of rapid growth or disassembly dependent on the cell's requirements. A multitude of functions can be performed by the cytoskeleton. Its primary function is to give the cell its shape and mechanical resistance to deformation, and through association with extracellular connective tissue and other cells it stabilizes entire tissues. The cytoskeleton can also contract, thereby deforming the cell and the cell's environment and allowing cells to migrate. Moreover, it is involved in many cell signaling pathways and in the uptake of extracellular material ( endocytosis), the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Instituto De Biología Y Medicina Experimental
The Experimental Medicine and Biology Institute ( es, Instituto de Biología y Medicina Experimental, IByME) is a research and development centre affiliated to the University of Buenos Aires, in Buenos Aires, Argentina. History The institute was privately founded on March 14, 1944 by Dr. Bernardo A. Houssay, Nobel Prize in Physiology and Medicine (1947) for his work in diabetes and the control of the carbohydrate metabolism. Drs. Eduardo Braun-Menéndez, Oscar Orías, Juan T. Lewis and Virgilio G. Foglia were co-founders. The founding of the Institute was motivated by the dismissal of Dr. Houssay, together with 150 other professors from the University of Buenos Aires, by the military government. Dr. Houssay became its director and brought to work with him several colleagues and students. The initiative was made possible by the support of Dr. Miguel F. Laphitzondo and others who granted financial contributions in memory of Juan B. Sauberán. The institute was the first organi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Massachusetts
The University of Massachusetts is the five-campus public university system and the only public research system in the Commonwealth of Massachusetts. The university system includes five campuses (Amherst, Boston, Dartmouth, Lowell, and a medical school in Worcester), a satellite campus in Springfield and also 25 campuses throughout California and Washington with the University of Massachusetts Global. The system administration is in Boston and Shrewsbury and is accredited by the New England Association of Schools and Colleges and across its campuses enrolls 75,065 students. Campuses The University of Massachusetts Amherst is the flagship and largest school in the UMass system. It was also the first one established, dating back to 1863, when it was founded as the Massachusetts Agricultural College. The University of Massachusetts Chan Medical School was founded in 1962, and is located in Worcester. The University of Massachusetts Boston, originally established in 1964, was mer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Membrane
The cell membrane (also known as the plasma membrane (PM) or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of all cells from the outside environment (the extracellular space). The cell membrane consists of a lipid bilayer, made up of two layers of phospholipids with cholesterols (a lipid component) interspersed between them, maintaining appropriate membrane fluidity at various temperatures. The membrane also contains membrane proteins, including integral proteins that span the membrane and serve as membrane transporters, and peripheral proteins that loosely attach to the outer (peripheral) side of the cell membrane, acting as enzymes to facilitate interaction with the cell's environment. Glycolipids embedded in the outer lipid layer serve a similar purpose. The cell membrane controls the movement of substances in and out of cells and organelles, being selectively permeable to ions a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Actin
Actin is a family of globular multi-functional proteins that form microfilaments in the cytoskeleton, and the thin filaments in muscle fibrils. It is found in essentially all eukaryotic cells, where it may be present at a concentration of over 100 μM; its mass is roughly 42 kDa, with a diameter of 4 to 7 nm. An actin protein is the monomeric subunit of two types of filaments in cells: microfilaments, one of the three major components of the cytoskeleton, and thin filaments, part of the contractile apparatus in muscle cells. It can be present as either a free monomer called G-actin (globular) or as part of a linear polymer microfilament called F-actin (filamentous), both of which are essential for such important cellular functions as the mobility and contraction of cells during cell division. Actin participates in many important cellular processes, including muscle contraction, cell motility, cell division and cytokinesis, vesicle and organelle movement, cell sign ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Branching Process
In probability theory, a branching process is a type of mathematical object known as a stochastic process, which consists of collections of random variables. The random variables of a stochastic process are indexed by the natural numbers. The original purpose of branching processes was to serve as a mathematical model of a population in which each individual in generation n produces some random number of individuals in generation n+1, according, in the simplest case, to a fixed probability distribution that does not vary from individual to individual. Branching processes are used to model reproduction; for example, the individuals might correspond to bacteria, each of which generates 0, 1, or 2 offspring with some probability in a single time unit. Branching processes can also be used to model other systems with similar dynamics, e.g., the spread of surnames in genealogy or the propagation of neutrons in a nuclear reactor. A central question in the the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ergodicity
In mathematics, ergodicity expresses the idea that a point of a moving system, either a dynamical system or a stochastic process, will eventually visit all parts of the space that the system moves in, in a uniform and random sense. This implies that the average behavior of the system can be deduced from the trajectory of a "typical" point. Equivalently, a sufficiently large collection of random samples from a process can represent the average statistical properties of the entire process. Ergodicity is a property of the system; it is a statement that the system cannot be reduced or factored into smaller components. Ergodic theory is the study of systems possessing ergodicity. Ergodic systems occur in a broad range of systems in physics and in geometry. This can be roughly understood to be due to a common phenomenon: the motion of particles, that is, geodesics on a hyperbolic manifold are divergent; when that manifold is compact, that is, of finite size, those orbits return to the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell (biology)
The cell is the basic structural and functional unit of life forms. Every cell consists of a cytoplasm enclosed within a membrane, and contains many biomolecules such as proteins, DNA and RNA, as well as many small molecules of nutrients and metabolites.Cell Movements and the Shaping of the Vertebrate Body in Chapter 21 of Molecular Biology of the Cell '' fourth edition, edited by Bruce Alberts (2002) published by Garland Science. The Alberts text discusses how the "cellular building blocks" move to shape developing embryos. It is also common to describe small molecules such as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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