David Hurst Molyneux
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David Hurst Molyneux
David Hurst Molyneux CMG (born 1943) is a British parasitologist who served as the Director of the Liverpool School of Tropical Medicine (1991–2000), where, as of 2018, he is an emeritus professor. He previously held the Chair of Biological Sciences at the University of Salford (1977–91), where he also served as Dean of the Faculty of Science. His research and advocacy have focused on what are now known as neglected tropical diseases, and Michael Barrett credits him (with Alan Fenwick and Peter Hotez) as among the earliest advocates of the campaign to focus international attention on this group of diseases in the early-to-mid 2000s. Biography Molyneux was born in Northwich in Cheshire in 1943, and educated at Denstone College, Staffordshire (1956–62). He attended Emmanuel College of the University of Cambridge, gaining a degree in zoology (1965) and a PhD in parasitology (1969). He received a DSc from the University of Salford (1992). His earliest position was as a ...
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David Molyneux (politician)
David Trevor Molyneux is a British Labour politician and leader of Wigan Metropolitan Borough Council in Greater Manchester. As leader he is also a member of the Greater Manchester Combined Authority and is the combined authority's portfolio lead for Resources and Investment. First elected to the council in 1982, Molyneux represents the ward of Ince. He was elected as leader of the council in 2018 following Peter Smith's departure from the role after 27 years in post. Molyneux was appointed Member of the Order of the British Empire (MBE) in the 2022 Birthday Honours The 2022 Queen's Birthday Honours are appointments by some of the 15 Commonwealth realms of Queen Elizabeth II to various orders and honours to reward and highlight good works by citizens of those countries. The Birthday Honours are awarded as par ... for services to local government and the community in Wigan. References Living people Labour Party (UK) councillors Leaders of local authorities of ...
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Emmanuel College, Cambridge
Emmanuel College is a constituent college of the University of Cambridge. The college was founded in 1584 by Sir Walter Mildmay, Chancellor of the Exchequer to Elizabeth I. The site on which the college sits was once a priory for Dominican monks, and the College Hall is built on the foundations of the monastery's nave. Emmanuel is one of the 16 "old colleges", which were founded before the 17th century. Emmanuel today is one of the larger Cambridge colleges; it has around 500 undergraduates, reading almost every subject taught within the University, and over 150 postgraduates. Among Emmanuel's notable alumni are Thomas Young, John Harvard, Graham Chapman and Sebastian Faulks. Three members of Emmanuel College have received Nobel Prizes: Ronald Norrish, George Porter (both Chemistry, 1967) and Frederick Hopkins (Medicine, 1929). In every year from 1998 until 2016, Emmanuel was among the top five colleges in the Tompkins Table, which ranks colleges according to end-of-year ex ...
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Albendazole
Albendazole (also known as albendazolum) is a broad-spectrum anthelmintic and antiprotozoal agent of the benzimidazole type. It is used for the treatment of a variety of intestinal parasite infections, including ascariasis, pinworm infection, hookworm infection, trichuriasis, strongyloidiasis, taeniasis, clonorchiasis, opisthorchiasis, cutaneous larva migrans, giardiasis, and gnathostomiasis, among other diseases. Common side effects include nausea, abdominal pain, and headache. Rare but potentially serious side effects include bone marrow suppression which usually improves on discontinuing the medication. Liver inflammation has been reported and those with prior liver problems are at greater risk. It is pregnancy category C in the United States and category D in Australia, meaning it may cause harm if taken by pregnant women. Albendazole was developed in 1975. It is on the World Health Organization's List of Essential Medicines. Medical uses Albendazole is an effective tr ...
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Antiparasitic
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases, such as those caused by helminths, amoeba, ectoparasites, parasitic fungi, and protozoa, among others. Antiparasitics target the parasitic agents of the infections by destroying them or inhibiting their growth; they are usually effective against a limited number of parasites within a particular class. Antiparasitics are one of the antimicrobial drugs which include antibiotics that target bacteria, and antifungals that target fungi. They may be administered orally, intravenously or topically. Broad-Spectrum antiparasitics, analogous to broad-spectrum antibiotics for bacteria, are antiparasitic drugs with efficacy in treating a wide range of parasitic infections caused by parasites from different classes. Types Broad-spectrum * Nitazoxanide Antiprotozoals * Melarsoprol (for treatment of sleeping sickness caused by ''Trypanosoma brucei'') * Eflornithine (for sleeping sickness) ...
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GlaxoSmithKline
GSK plc, formerly GlaxoSmithKline plc, is a British multinational pharmaceutical and biotechnology company with global headquarters in London, England. Established in 2000 by a merger of Glaxo Wellcome and SmithKline Beecham. GSK is the tenth largest pharmaceutical company and #294 on the 2022 ''Fortune'' Global 500, ranked behind other pharmaceutical companies China Resources, Sinopharm, Johnson & Johnson, Pfizer, Roche, AbbVie, Novartis, Bayer, and Merck. The company has a primary listing on the London Stock Exchange and is a constituent of the FTSE 100 Index. , it had a market capitalisation of £70 billion, the eighth largest on the London Stock Exchange. It has a secondary listing on the New York Stock Exchange. The company developed the first malaria vaccine, RTS,S, which it said in 2014 it would make available for five percent above cost. Legacy products developed at GSK include several listed in the World Health Organization's List of Essential Medicines, such ...
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Department For International Development
, type = Department , logo = DfID.svg , logo_width = 180px , logo_caption = , picture = File:Admiralty Screen (411824276).jpg , picture_width = 180px , picture_caption = Department for International Development (London office) (far right) , seal = , seal_width = , seal_caption = , formed = 1997 , preceding1 = Ministry of Overseas Development (ODM) , preceding2 = Overseas Development Administration (ODA) , dissolved = 2 September 2020 , superseding = Foreign, Commonwealth and Development Office , jurisdiction = United Kingdom , headquarters = 22 Whitehall, London, EnglandEast Kilbride, Scotland , employees = , budget = £13.4bn , minister1_name = , minister1_pfo = , minister2_name = , minister2_pfo = , minister3_name = , minister3_pfo = , chief1_name = , chief1_position = , chief2_name = , chief2_position = , child1_agency = , website = , footnotes = , chief3_name = , chief3_position = , chief4_name = , chief4_position = , chief ...
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Filariasis
Filariasis is a parasitic disease caused by an infection with roundworms of the Filarioidea type. These are spread by blood-feeding insects such as black flies and mosquitoes. They belong to the group of diseases called helminthiases. These parasites exist in the wild in subtropical parts of southern Asia, Africa, the South Pacific, and parts of South America. One does not acquire them in temperate areas like Europe or the United States. Eight known filarial worms have humans as a definitive host. These are divided into three groups according to the part of the body they affect: * Lymphatic filariasis is caused by the worms ''Wuchereria bancrofti'', ''Brugia malayi'', and ''Brugia timori''. These worms occupy the lymphatic system, including the lymph nodes; in chronic cases, these worms lead to the syndrome of ''elephantiasis''. * Subcutaneous filariasis is caused by ''Loa loa'' (the eye worm), ''Mansonella streptocerca'', and ''Onchocerca volvulus''. These worms occupy the la ...
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Onchocerciasis
Onchocerciasis, also known as river blindness, is a disease caused by infection with the parasitic worm ''Onchocerca volvulus''. Symptoms include severe itching, bumps under the skin, and blindness. It is the second-most common cause of blindness due to infection, after trachoma. The parasite worm is spread by the bites of a black fly of the ''Simulium'' type. Usually, many bites are required before infection occurs. These flies live near rivers, hence the common name of the disease. Once inside a person, the worms create larvae that make their way out to the skin, where they can infect the next black fly that bites the person. There are a number of ways to make the diagnosis, including: placing a biopsy of the skin in normal saline and watching for the larva to come out; looking in the eye for larvae; and looking within the bumps under the skin for adult worms. A vaccine against the disease does not exist. Prevention is by avoiding being bitten by flies. This may include the ...
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Burkina Faso
Burkina Faso (, ; , ff, 𞤄𞤵𞤪𞤳𞤭𞤲𞤢 𞤊𞤢𞤧𞤮, italic=no) is a landlocked country in West Africa with an area of , bordered by Mali to the northwest, Niger to the northeast, Benin to the southeast, Togo and Ghana to the south, and the Ivory Coast to the southwest. It has a population of 20,321,378. Previously called Republic of Upper Volta (1958–1984), it was renamed Burkina Faso by President Thomas Sankara. Its citizens are known as ''Burkinabè'' ( ), and its capital and largest city is Ouagadougou. The largest ethnic group in Burkina Faso is the Mossi people, who settled the area in the 11th and 13th centuries. They established powerful kingdoms such as the Ouagadougou, Tenkodogo, and Yatenga. In 1896, it was colonized by the French as part of French West Africa; in 1958, Upper Volta became a self-governing colony within the French Community. In 1960, it gained full independence with Maurice Yaméogo as president. Throughout the decades post in ...
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African Trypanosomiasis
African trypanosomiasis, also known as African sleeping sickness or simply sleeping sickness, is an insect-borne parasitic infection of humans and other animals. It is caused by the species ''Trypanosoma brucei''. Humans are infected by two types, ''Trypanosoma brucei gambiense'' (TbG) and '' Trypanosoma brucei rhodesiense'' (TbR). TbG causes over 98% of reported cases. Both are usually transmitted by the bite of an infected tsetse fly and are most common in rural areas. Initially, the first stage of the disease is characterized by fevers, headaches, itchiness, and joint pains, beginning one to three weeks after the bite. Weeks to months later, the second stage begins with confusion, poor coordination, numbness, and trouble sleeping. Diagnosis is by finding the parasite in a blood smear or in the fluid of a lymph node. A lumbar puncture is often needed to tell the difference between first- and second-stage disease. If the disease is not treated quickly it can lead to death. P ...
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World Health Organization
The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of health". Headquartered in Geneva, Switzerland, it has six regional offices and 150 field offices worldwide. The WHO was established on 7 April 1948. The first meeting of the World Health Assembly (WHA), the agency's governing body, took place on 24 July of that year. The WHO incorporated the assets, personnel, and duties of the League of Nations' Health Organization and the , including the International Classification of Diseases (ICD). Its work began in earnest in 1951 after a significant infusion of financial and technical resources. The WHO's mandate seeks and includes: working worldwide to promote health, keeping the world safe, and serve the vulnerable. It advocates that a billion more people should have: universal health care coverag ...
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Leishmania
''Leishmania'' is a parasitic protozoan, a single-celled organism of the genus '' Leishmania'' that are responsible for the disease leishmaniasis. They are spread by sandflies of the genus ''Phlebotomus'' in the Old World, and of the genus ''Lutzomyia'' in the New World. At least 93 sandfly species are proven or probable vectors worldwide.WHO (2010) Annual report. Geneva Their primary hosts are vertebrates; ''Leishmania'' commonly infects hyraxes, canids, rodents, and humans. History Members of an ancient genus of the ''Leishmania'' parasite, ''Paleoleishmania'', have been detected in fossilized sand flies dating back to the early Cretaceous period. The first written reference to the conspicuous symptoms of cutaneous leishmaniasis surfaced in the Paleotropics within oriental texts dating back to the 7th century BC (allegedly transcribed from sources several hundred years older, between 1500 and 2000 BC). Due to its broad and persistent prevalence throughout antiquity as a mys ...
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