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Das Reizleitungssystem Des Säugetierherzens
''Das Reizleitungssystem des Säugetierherzens'' (English: "''The Conduction System of the Mammalian Heart''") is a scientific monograph published in 1906 by Sunao Tawara. It has been recognized by cardiologists as a monumental discovery, and a milestone in cardiac electrophysiology". The monograph revealed the existence of the atrioventricular node and the function of Purkinje cells. It was used by Arthur Keith and Martin Flack as a detailed guide in their attempts to verify the existence of the Bundle of His, which subsequently led to their discovery of the sinoatrial node. Throughout the beginning of the 20th century, Tawara's monograph influenced the work of many cardiologists and it was later cited by Willem Einthoven in his anatomical interpretation of the electrocardiogram. Background Prior to Tawara's discoveries, it was assumed that electrical conduction through the Bundle of His was slow, because of the long interval between atrial and ventricular contractions. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Monograph
A monograph is a specialist work of writing (in contrast to reference works) or exhibition on a single subject or an aspect of a subject, often by a single author or artist, and usually on a scholarly subject. In library cataloging, ''monograph'' has a broader meaning—that of a nonserial publication complete in one volume (book) or a definite number of volumes. Thus it differs from a serial or periodical publication such as a magazine, academic journal, or newspaper. In this context only, books such as novels are considered monographs.__FORCETOC__ Academia The English term "monograph" is derived from modern Latin "monographia", which has its root in Greek. In the English word, "mono-" means "single" and "-graph" means "something written". Unlike a textbook, which surveys the state of knowledge in a field, the main purpose of a monograph is to present primary research and original scholarship ascertaining reliable credibility to the required recipient. This research is prese ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aschoff Bodies
In medicine, Aschoff bodies are nodules found in the hearts of individuals with rheumatic fever. They result from inflammation in the heart muscle and are characteristic of rheumatic heart disease. These nodules were discovered independently by Ludwig Aschoff and Paul Rudolf Geipel, and for this reason they are occasionally called Aschoff-Geipel bodies. Appearance Microscopically, Aschoff bodies are areas of inflammation of the connective tissue of the heart, or focal interstitial inflammation. Fully developed Aschoff bodies are granulomatous structures consisting of fibrinoid change, lymphocytic infiltration, occasional plasma cells, and characteristically abnormal macrophages surrounding necrotic centres. Some of these macrophages may fuse to form multinucleated giant cells. Others may become Anitschkow cells or "caterpillar cells," so named because of the appearance of their chromatin. They are pathognomic foci of fibrinoid necrosis found in many sites, most often the m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heart Rhythm
The cardiac conduction system (CCS) (also called the electrical conduction system of the heart) transmits the signals generated by the sinoatrial node – the heart's pacemaker, to cause the heart muscle to contract, and pump blood through the body's circulatory system. The pacemaking signal travels through the right atrium to the atrioventricular node, along the bundle of His, and through the bundle branches to Purkinje fibers in the walls of the ventricles. The Purkinje fibers transmit the signals more rapidly to stimulate contraction of the ventricles. The conduction system consists of specialized heart muscle cells, situated within the myocardium. There is a skeleton of fibrous tissue that surrounds the conduction system which can be seen on an ECG. Dysfunction of the conduction system can cause irregular heart rhythms including rhythms that are too fast or too slow. Structure Electrical signals arising in the SA node (located in the right atrium) stimulate the at ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electrocardiography
Electrocardiography is the process of producing an electrocardiogram (ECG or EKG), a recording of the heart's electrical activity. It is an electrogram of the heart which is a graph of voltage versus time of the electrical activity of the heart using electrodes placed on the skin. These electrodes detect the small electrical changes that are a consequence of cardiac muscle depolarization followed by repolarization during each cardiac cycle (heartbeat). Changes in the normal ECG pattern occur in numerous cardiac abnormalities, including cardiac rhythm disturbances (such as atrial fibrillation and ventricular tachycardia), inadequate coronary artery blood flow (such as myocardial ischemia and myocardial infarction), and electrolyte disturbances (such as hypokalemia and hyperkalemia). Traditionally, "ECG" usually means a 12-lead ECG taken while lying down as discussed below. However, other devices can record the electrical activity of the heart such as a Holter monitor but also s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
European Journal Of Physiology
European, or Europeans, or Europeneans, may refer to: In general * ''European'', an adjective referring to something of, from, or related to Europe ** Ethnic groups in Europe ** Demographics of Europe ** European cuisine, the cuisines of Europe and other Western countries * ''European'', an adjective referring to something of, from, or related to the European Union ** Citizenship of the European Union ** Demographics of the European Union In publishing * ''The European'' (1953 magazine), a far-right cultural and political magazine published 1953–1959 * ''The European'' (newspaper), a British weekly newspaper published 1990–1998 * ''The European'' (2009 magazine), a German magazine first published in September 2009 *''The European Magazine'', a magazine published in London 1782–1826 *''The New European'', a British weekly pop-up newspaper first published in July 2016 Other uses * * Europeans (band), a British post-punk group, from Bristol See also * * * Europe (disambi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Lancet
''The Lancet'' is a weekly peer-reviewed general medical journal and one of the oldest of its kind. It is also the world's highest-impact academic journal. It was founded in England in 1823. The journal publishes original research articles, review articles ("seminars" and "reviews"), editorials, book reviews, correspondence, as well as news features and case reports. ''The Lancet'' has been owned by Elsevier since 1991, and its editor-in-chief since 1995 has been Richard Horton. The journal has editorial offices in London, New York City, and Beijing. History ''The Lancet'' was founded in 1823 by Thomas Wakley, an English surgeon who named it after the surgical instrument called a lancet (scalpel). Members of the Wakley family retained editorship of the journal until 1908. In 1921, ''The Lancet'' was acquired by Hodder & Stoughton. Elsevier acquired ''The Lancet'' from Hodder & Stoughton in 1991. Impact According to the ''Journal Citation Reports'', the journal has a 202 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinical Cardiology
''Clinical Cardiology'' is a monthly peer-reviewed medical journal covering cardiology that was established in 1978. It is published by John Wiley & Sons and the editor-in-chief is A. John Camm (St George's, University of London). It is an official journal of the American Society for Preventive Cardiology. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 2.882. References External links * Publications established in 1978 Cardiology journals Monthly journals English-language journals Wiley (publisher) academic journals {{Cardiology-journal-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heart (journal)
''Heart'' is a biweekly peer-reviewed medical journal covering all areas of cardiovascular medicine and surgery. It is the official journal of the British Cardiovascular Society. It was established in 1939 as the ''British Heart Journal'' and is published by the BMJ Group. The name was changed from ''British Heart Journal'' to ''Heart'' in 1996 with the start of volume 75. The editor-in-chief is Catherine Otto (University of Washington). A sister journal, '' Open Heart'', was established in 2010 with the aim of covering cardiovascular research with less emphasis on novelty or priority. History In 2010, ''Heart'' established a sister journal, ''Heart Asia''. It was the official journal of the Asia Pacific Heart Association and aimed to focus on cardiovascular research in the Asia Pacific region. In 2019, the journal ceased publication. Abstracting and indexing The journal is abstracted and indexed by Index Medicus, Science Citation Index Expanded, EMBASE, and Scopus. According ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
James Mackenzie (cardiologist)
Sir James Mackenzie (12 April 1853 – 26 January 1925) was a Scottish Cardiology, cardiologist who was a pioneer in the study of cardiac arrhythmias. Due to his work in the cardiac field he is known as a research giant in primary care, and was knighted by King George V in 1915 Birthday Honours, 1915. Biography James Mackenzie was born at Pictonhill in Scone, Scotland, Scone, where his father was a farmer. He left school at Perth Academy aged 14 and was apprenticed to a chemist. In 1873 he was offered a partnership in the chemist's firm but turned it down in order to study medicine. After private tuition in Latin he passed his entrance examination for the University of Edinburgh in October 1874 and qualified as a doctor in 1878. After completing his residency in Edinburgh, Mackenzie became a general practitioner in borough of Burnley in Lancashire, England where he continued to practice medicine for more than a quarter of a century. While he was engaged in a busy practice, he ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Purkinje Fibers
The Purkinje fibers (; often incorrectly ; Purkinje tissue or subendocardial branches) are located in the inner ventricular walls of the heart, just beneath the endocardium in a space called the subendocardium. The Purkinje fibers are specialized conducting fibers composed of electrically excitable cells. They are larger than cardiomyocytes with fewer myofibrils and many mitochondria. They conduct cardiac action potentials more quickly and efficiently than any of the other cells in the heart's electrical conduction system. Purkinje fibers allow the heart's conduction system to create synchronized contractions of its ventricles, and are essential for maintaining a consistent heart rhythm. Histology Purkinje fibers are a unique cardiac end-organ. Further histologic examination reveals that these fibers are split in ventricles walls. The electrical origin of atrial Purkinje fibers arrives from the sinoatrial node. Given no aberrant channels, the Purkinje fibers are distinct ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bundle Branch
The bundle branches, or Tawara branches, are offshoots of the bundle of His in the heart's ventricle. They play an integral role in the electrical conduction system of the heart by transmitting cardiac action potentials from the bundle of His to the Purkinje fibers. Structure There are two branches of the bundle of His: the left bundle branch and the right bundle branch, both of which are located along the interventricular septum. The left bundle branch further divides into the left anterior fascicle and the left posterior fascicle. These structures lead to a network of thin filaments known as Purkinje fibers. They play an integral role in the electrical conduction system of the heart by transmitting cardiac action potentials to the Purkinje fibers. Clinical significance When a bundle branch or their fascicles becomes injured (by underlying heart disease, myocardial infarction, or cardiac surgery), it may cease to conduct electrical impulses appropriately, resulting in alte ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Septum
In biology, a septum (Latin for ''something that encloses''; plural septa) is a wall, dividing a cavity or structure into smaller ones. A cavity or structure divided in this way may be referred to as septate. Examples Human anatomy * Interatrial septum, the wall of tissue that is a sectional part of the left and right atria of the heart * Interventricular septum, the wall separating the left and right ventricles of the heart * Lingual septum, a vertical layer of fibrous tissue that separates the halves of the tongue. *Nasal septum: the cartilage wall separating the nostrils of the nose * Alveolar septum: the thin wall which separates the alveoli from each other in the lungs * Orbital septum, a palpebral ligament in the upper and lower eyelids * Septum pellucidum or septum lucidum, a thin structure separating two fluid pockets in the brain * Uterine septum, a malformation of the uterus * Vaginal septum, a lateral or transverse partition inside the vagina * Intermuscular sep ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
