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Daphnoretin
Daphnoretin is a protein kinase C activator isolated from ''Wikstroemia indica'' C.A. Mey, one of the 50 fundamental herbs in traditional Chinese medicine Traditional Chinese medicine (TCM) is an alternative medical practice drawn from traditional medicine in China. It has been described as "fraught with pseudoscience", with the majority of its treatments having no logical mechanism of action .... It has also been found to occur in '' Stellera chamaejasme'' - the single species in a genus closely related to ''Wikstroemia'' within the family Thymelaceae.''Medicinal Plants in Mongolia'' pub. World Health Organization, Regional Office for the Western Pacific Region 2013/ref> References Wikstroemia Coumarins Protein kinase C activators Resorcinol ethers {{organic-compound-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein Kinase C
In cell biology, Protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins, or a member of this family. PKC enzymes in turn are activated by signals such as increases in the concentration of diacylglycerol (DAG) or calcium ions (Ca2+). Hence PKC enzymes play important roles in several signal transduction cascades. In biochemistry, the PKC family consists of fifteen isozymes in humans. They are divided into three subfamilies, based on their second messenger requirements: conventional (or classical), novel, and atypical. Conventional (c)PKCs contain the isoforms α, βI, βII, and γ. These require Ca2+, DAG, and a phospholipid such as phosphatidylserine for activation. Novel (n)PKCs include the δ, ε, η, and θ isoforms, and require DAG, but do not require Ca2+ for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wikstroemia Indica
''Wikstroemia indica'', also known as tie bush, Indian stringbush, bootlace bush, or small-leaf salago () is a small shrub with glossy leaves, small greenish-yellow flowers and toxic red fruits. It grows in forests and on rocky, shrubby slopes in central and southeastern China, Vietnam, India, Australia and the Philippines. Toxicity ''W. indica'' is toxic and the poisoning caused by ''W. indica'' leads to dizziness, blurred vision, nausea, vomiting, abdominal distension, abdominal pain and diarrhea. Medicinal uses It is one of the 50 fundamental herbs used in traditional Chinese medicine. As a traditional Chinese herb, this plant has long been employed as an antipyretic, detoxicant, expectorant, vermifuge, and abortifacient in clinical practice in China. Chemicals An alcoholic extract of the plant was found to contain daphnoretin, chrysophanol, myricitrime and rutin. The extract of ''W. indica'' displays antimicrobial and anti-inflammatory activities ''in vitro ''In vi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Traditional Chinese Medicine
Traditional Chinese medicine (TCM) is an alternative medical practice drawn from traditional medicine in China. It has been described as "fraught with pseudoscience", with the majority of its treatments having no logical mechanism of action. Medicine in traditional China encompassed a range of sometimes competing health and healing practices, folk beliefs, literati theory and Confucian philosophy, herbal remedies, food, diet, exercise, medical specializations, and schools of thought. In the early twentieth century, Chinese cultural and political modernizers worked to eliminate traditional practices as backward and unscientific. Traditional practitioners then selected elements of philosophy and practice and organized them into what they called "Chinese medicine" (''Zhongyi''). In the 1950s, the Chinese government sponsored the integration of Chinese and Western medicine, and in the Great Proletarian Cultural Revolution of the 1960s, promoted Chinese medicine as inexpensive a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stellera Chamaejasme
''Stellera'' is a genus of flowering plant in the family Thymelaeaceae, with a single species ''Stellera chamaejasme'' found in mountainous regions of Central Asia, China, Siberia and South Asia. ''S. chamaejasme'' is a herbaceous perennial plant with heads of white, pink or yellow flowers, grown as an ornamental plant in rock gardens and alpine houses, but considered a weed playing a rôle in the desertification of grasslands in parts of its native range. Like many others of its family, it is a poisonous plant with medicinal and other useful properties. Common names Two common names recorded for the plant in Mongolian are одои далан туруу ''odoi dalan turuu'' and чонын Чолбодос ''choniin'' (="of the wolf") ''cholbodos'' (="?"), and a common name for the plant in Tibetan is ''rejag''.Medicinal Plants in Mongolia pub. World Health Organization, Regional Office for the Western Pacific Region 2013/ref> Description ''Stellera chamaejasme'' i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thymelaceae
The Thymelaeaceae are a cosmopolitan family of flowering plants composed of 50 genera (listed below) and 898 species.Zachary S. Rogers (2009 onwards)A World Checklist of Thymelaeaceae (version 1) Missouri Botanical Garden Website, St. Louis. It was established in 1789 by Antoine Laurent de Jussieu.Antoine Laurent de Jussieu ''Genera Plantarum'', page 76. Herrisant & Barrois, Paris. The Thymelaeaceae are mostly trees and shrubs, with a few vines and herbaceous plants. Description This is not intended as a full botanical description, but only as a few notes on some of the conspicuous or unusual traits of the family when ''Tepuianthus'' is excluded. The bark is usually shiny and fibrous. Attempts to break the stem often result in a strip of bark peeling down the side.Ernst Schmidt, Mervyn Lotter and Warren McCleland The number of stamens is usually once or twice the number of calyx lobes. If twice, then they often occur in two well separated series. Exceptions include ''Gonys ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wikstroemia
''Wikstroemia'' is a genus of 55-70 species of flowering shrubs and small trees in the mezereon family, Thymelaeaceae. Hawaiian species are known by the common name ‘ākia. Medicinal uses '' Wikstroemia indica'' () is one of the 50 fundamental herbs used in traditional Chinese medicine. Paper making The bark fibres of several species of ''Wikstroemia'' are used to make paper. Species *'' Wikstroemia albiflora'' *'' Wikstroemia alternifolia'' *'' Wikstroemia angustifolia'' *'' Wikstroemia australis'' – Norfolk Island *'' Wikstroemia balansae'' *'' Wikstroemia bicornuta'' Hillebr. – alpine false ohelo ( Lānai and Maui, Hawaii) *'' Wikstroemia chuii'' *'' Wikstroemia coriacea'' Sol. ex Seem. *'' Wikstroemia elliptica'' *'' Wikstroemia forbesii'' Skottsb. – Molokai false ohelo ( Molokai, Hawaii) *'' Wikstroemia fruticosa'' *'' Wikstroemia furcata'' (Hillebr.) Rock – forest false ohelo ( Kauai, Hawaii) *''Wikstroemia ganpi'' *'' Wikstroemia gracilis'' *'' Wikstroem ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coumarins
Coumarin () or 2''H''-chromen-2-one is an aromatic organic chemical compound with formula . Its molecule can be described as a benzene molecule with two adjacent hydrogen atoms replaced by a lactone-like chain , forming a second six-membered heterocycle that shares two carbons with the benzene ring. It can be placed in the benzopyrone chemical class and considered as a lactone. Coumarin is a colorless crystalline solid with a sweet odor resembling the scent of vanilla and a bitter taste. It is found in many plants, where it may serve as a chemical defense against predators. By inhibiting synthesis of vitamin K, a related compound is used as the prescription drug warfarin – an anticoagulant – to inhibit formation of blood clots, deep vein thrombosis, and pulmonary embolism. Etymology Coumarin is derived from ''coumarou'', the French word for the tonka bean. The word ''tonka'' for the tonka bean is taken from the Galibi (Carib) tongue spoken by natives of French Guia ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein Kinase C Activators
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residues in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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