Chinese Coptis
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Chinese Coptis
''Coptis chinensis'', the Chinese goldthread, is a species of goldthread flowering plant native to China. Etymology *''Coptis chinensis'' Franch. var. ''chinensis''''Coptis chinensis''
in BoDD – Botanical Dermatology Database
**(syn. ''Coptis teeta'' Wallich var. ''chinensis'')


Chemical constituents

The of ''Coptis chinensis'' contain the

Franch
Franch is a surname. Notable persons with that surname include: * Adrianna Franch (born 1990), American football (soccer) player * Josep Franch (born 1991), Spanish basketball player * Pau Franch (born 1988), Spanish football (soccer) player See also * French (other) *France France (), officially the French Republic ( ), is a country primarily located in Western Europe. It also comprises of Overseas France, overseas regions and territories in the Americas and the Atlantic Ocean, Atlantic, Pacific Ocean, Pac ... {{surname Catalan-language surnames ...
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Species
In biology, a species is the basic unit of classification and a taxonomic rank of an organism, as well as a unit of biodiversity. A species is often defined as the largest group of organisms in which any two individuals of the appropriate sexes or mating types can produce fertile offspring, typically by sexual reproduction. Other ways of defining species include their karyotype, DNA sequence, morphology, behaviour or ecological niche. In addition, paleontologists use the concept of the chronospecies since fossil reproduction cannot be examined. The most recent rigorous estimate for the total number of species of eukaryotes is between 8 and 8.7 million. However, only about 14% of these had been described by 2011. All species (except viruses) are given a two-part name, a "binomial". The first part of a binomial is the genus to which the species belongs. The second part is called the specific name or the specific epithet (in botanical nomenclature, also sometimes i ...
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Coptis
''Coptis'' (goldthread or canker root) is a genus of between 10–15 species of flowering plants in the family Ranunculaceae, native to Asia and North America. Species ;Selected species *''Coptis aspleniifolia'' - fernleaf goldthread, spleenwort-leaf goldthread *''Coptis chinensis'' - Chinese goldthread, ''Huang lian'' in Chinese () *''Coptis deltoidea'' *''Coptis trifolia'' (syn. Coptis groenlandica) *''Coptis japonica'' - Japanese goldthread, ''Riben huang lian'' in Chinese () *''Coptis laciniata'' - Oregon goldthread: California, Oregon, Washington State *''Coptis occidentalis'' - Idaho goldthread: Idaho, Montana, Washington *''Coptis omeiensis'' *''Coptis quinquefolia'' *''Coptis quinquesecta'' *''Coptis teeta'' - Yunnan goldthread, ''Yunnan huang lian'' in Chinese () *''Coptis trifolia'' - threeleaf goldthread, savoyane, canker-root (Eastern Eurasia, Greenland, Saint Pierre and Miquelon, Canada, USA) Uses ''Coptis teeta'' is used as a medicinal herb in China and the Easter ...
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China
China, officially the People's Republic of China (PRC), is a country in East Asia. It is the world's most populous country, with a population exceeding 1.4 billion, slightly ahead of India. China spans the equivalent of five time zones and borders fourteen countries by land, the most of any country in the world, tied with Russia. Covering an area of approximately , it is the world's third largest country by total land area. The country consists of 22 provinces, five autonomous regions, four municipalities, and two Special Administrative Regions (Hong Kong and Macau). The national capital is Beijing, and the most populous city and financial center is Shanghai. Modern Chinese trace their origins to a cradle of civilization in the fertile basin of the Yellow River in the North China Plain. The semi-legendary Xia dynasty in the 21st century BCE and the well-attested Shang and Zhou dynasties developed a bureaucratic political system to serve hereditary monarchies, or dyna ...
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Nathaniel Wallich
Nathaniel Wolff Wallich FRS FRSE (28 January 1786 – 28 April 1854) was a surgeon and botanist of Danish origin who worked in India, initially in the Danish settlement near Calcutta and later for the Danish East India Company and the British East India Company. He was involved in the early development of the Calcutta Botanical Garden, describing many new plant species and developing a large herbarium collection which was distributed to collections in Europe. Several of the plants that he collected were named after him. Early life and education Nathaniel Wallich was born in Copenhagen in 1786 as Nathan Wulff Wallich. His father Wulff Lazarus Wallich (1756–1843) was a Sephardic Jewish merchant originally from the Holsatian town Altona near Hamburg, who settled in Copenhagen late in the 18th century. His mother was Hanne née Jacobson (1757–1839). Wallich attended the Royal Academy of Surgeons in Copenhagen, where his professors trained in the botanical science included ...
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Rhizomes
In botany and dendrology, a rhizome (; , ) is a modified subterranean plant stem that sends out roots and shoots from its nodes. Rhizomes are also called creeping rootstalks or just rootstalks. Rhizomes develop from axillary buds and grow horizontally. The rhizome also retains the ability to allow new shoots to grow upwards. A rhizome is the main stem of the plant that runs underground horizontally. A stolon is similar to a rhizome, but a stolon sprouts from an existing stem, has long internodes, and generates new shoots at the end, such as in the strawberry The garden strawberry (or simply strawberry; ''Fragaria × ananassa'') is a widely grown hybrid species of the genus '' Fragaria'', collectively known as the strawberries, which are cultivated worldwide for their fruit. The fruit is widely ap ... plant. In general, rhizomes have short internodes, send out roots from the bottom of the nodes, and generate new upward-growing shoots from the top of the nodes. A stem tub ...
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Isoquinoline Alkaloids
Isoquinoline alkaloids are natural products of the group of alkaloids, which are chemically derived from isoquinoline. They form the largest group among the alkaloids. Isoquinoline alkaloids can be further classified based on their different chemical basic structures. The most common structural types are the benzylisoquinolines and the aporphines.Bettina Ruff: ''Chemische und biochemische Methoden zur stereoselektiven Synthese von komplexen Naturstoffen.'' Verlag Logos, Berlin 2012, , S. 8. () According to current knowledge, a total of about 2500 isoquinoline alkaloids are known nowadays, which are mainly formed by plants.Jennifer M. Finefield, David H. Sherman, Martin Kreitman, Robert M. Williams: ''Enantiomere Naturstoffe: Vorkommen und Biogenese.'' In: ''Angewandte Chemie.'' Wiley-VCH, Weinheim 2012, doi:10.1002/ange.201107204, S. 4905–4915. Known examples Morphin - Morphine.svg, Morphine Codein - Codeine.svg, Codeine Papaverin - Papaverine.svg, Papaverine Berbe ...
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Berberine
Berberine is a quaternary ammonium salt from the protoberberine group of benzylisoquinoline alkaloids found in such plants as ''Berberis vulgaris'' (barberry), ''Berberis aristata'' (tree turmeric), ''Mahonia aquifolium'' (Oregon grape), ''Hydrastis canadensis'' (goldenseal), ''Xanthorhiza simplicissima'' (yellowroot), ''Phellodendron amurense'' (Amur cork tree), ''Coptis chinensis'' (Chinese goldthread), ''Tinospora cordifolia'', ''Argemone mexicana'' (prickly poppy), and ''Eschscholzia californica'' (Californian poppy). Berberine is usually found in the roots, rhizomes, stems, and bark. Due to its yellow color, ''Berberis'' species were used to dye wool, leather, and wood. Under ultraviolet light, berberine shows a strong yellow fluorescence, making it useful in histology for staining heparin in mast cells. As a natural dye, berberine has a color index of 75160. Research and adverse effects The safety of using berberine for any condition is not adequately defined by high-qua ...
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Palmatine
Palmatine is a protoberberine alkaloid found in several plants including ''Phellodendron amurense'', ''Coptis Chinensis'' (Rhizoma coptidis, chinese goldthread) and '' Corydalis yanhusuo'', ''Tinospora cordifolia'' (gurjo, heart-leaved moonseed), ''Tinospora sagittata'', ''Phellodendron amurense'' (amur cork tree), '' Stephania yunnanensis.'' It is the major component of the protoberberine extract from ''Enantia chlorantha''. It has been studied for its potential use in the treatment of jaundice, dysentery, hypertension, inflammation, and liver-related diseases. This compound also has weak ''in vitro'' activity against flavivirus. Pharmacology Neuroprotective activity Palmatine can be used to treat Alzheimer’s disease, mainly by inhibiting the activity of acetylcholinesterase (AChE), butyrylcholinesterase (BChE) and neuraminidase-1 (NA-1). It was found, that the positively charged nitrogen on palmatine binds in the gorge of active sire of AChE. Research show that palma ...
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Coptisine
Coptisine is an alkaloid found in Chinese goldthread (''Coptis chinensis''), greater celandine, and opium. Famous for the bitter taste that it produces, it is used in Chinese herbal medicine along with the related compound berberine Berberine is a quaternary ammonium salt from the protoberberine group of benzylisoquinoline alkaloids found in such plants as ''Berberis vulgaris'' (barberry), '' Berberis aristata'' (tree turmeric), '' Mahonia aquifolium'' (Oregon grape), '' Hyd ... for digestive disorders caused by bacterial infections. References Isoquinoline alkaloids Benzodioxoles Quaternary ammonium compounds {{alkaloid-stub ...
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Chinese Herbology
Chinese herbology () is the theory of traditional Chinese herbal therapy, which accounts for the majority of treatments in traditional Chinese medicine (TCM). A ''Nature'' editorial described TCM as "fraught with pseudoscience", and said that the most obvious reason why it has not delivered many cures is that the majority of its treatments have no logical mechanism of action. The term herbology is misleading in the sense that, while plant elements are by far the most commonly used substances, animal, human, and mineral products are also utilized, among which some are poisonous. In the ''Huangdi Neijing'' they are referred to as () which means toxin, poison, or medicine. Paul U. Unschuld points out that this is similar etymology to the Greek '' pharmakon'' and so he uses the term "pharmaceutic". Thus, the term "medicinal" (instead of herb) is usually preferred as a translation for (). Research into the effectiveness of traditional Chinese herbal therapy is of poor quality and ...
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Traditional Chinese Medicine
Traditional Chinese medicine (TCM) is an alternative medical practice drawn from traditional medicine in China. It has been described as "fraught with pseudoscience", with the majority of its treatments having no logical mechanism of action. Medicine in traditional China encompassed a range of sometimes competing health and healing practices, folk beliefs, literati theory and Confucian philosophy, herbal remedies, food, diet, exercise, medical specializations, and schools of thought. In the early twentieth century, Chinese cultural and political modernizers worked to eliminate traditional practices as backward and unscientific. Traditional practitioners then selected elements of philosophy and practice and organized them into what they called "Chinese medicine" (''Zhongyi''). In the 1950s, the Chinese government sponsored the integration of Chinese and Western medicine, and in the Great Proletarian Cultural Revolution of the 1960s, promoted Chinese medicine as inexpensive a ...
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