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Carlos Bustamante (biophysicist)
Carlos José Bustamante (born 1951 in Lima, Peru) is a Peruvian-American scientist. He is a member of the National Academy of Sciences. Biography Carlos Bustamante is a Howard Hughes Medical Institute (HHMI) investigator, professor of molecular and cell biology, physics, and chemistry at the University of California, Berkeley, and Biophysicist Faculty Scientist at the Lawrence Berkeley National Laboratory. Bustamante studied medicine at National University of San Marcos before discovering his true interest in biochemistry. He received his BSc from Cayetano Heredia University in Lima, his MSc in biochemistry from National University of San Marcos in Lima, and his PhD in biophysics from UC Berkeley, where he studied with Ignacio Tinoco, Jr. As a postdoctoral fellow at the Lawrence Berkeley National Laboratory, Bustamante studied with Marcos Maestre. Before moving to Berkeley, he was an HHMI investigator at the University of Oregon. Research focus Carlos Bustamante uses novel metho ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lima
Lima ( ; ), originally founded as Ciudad de Los Reyes (City of The Kings) is the capital and the largest city of Peru. It is located in the valleys of the Chillón River, Chillón, Rímac River, Rímac and Lurín Rivers, in the desert zone of the central coastal part of the country, overlooking the Pacific Ocean. Together with the seaside city of Callao, it forms a contiguous urban area known as the Lima Metropolitan Area. With a population of more than 9.7 million in its urban area and more than 10.7 million in its metropolitan area, Lima is one of the largest cities in the Americas. Lima was named by natives in the agricultural region known by native Peruvians as ''Limaq''. It became the capital and most important city in the Viceroyalty of Peru. Following the Peruvian War of Independence, it became the capital of the Republic of Peru (República del Perú). Around one-third of the national population now lives in its Lima Metropolitan Area, metropolitan area. The city of Li ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physics
Physics is the natural science that studies matter, its fundamental constituents, its motion and behavior through space and time, and the related entities of energy and force. "Physical science is that department of knowledge which relates to the order of nature, or, in other words, to the regular succession of events." Physics is one of the most fundamental scientific disciplines, with its main goal being to understand how the universe behaves. "Physics is one of the most fundamental of the sciences. Scientists of all disciplines use the ideas of physics, including chemists who study the structure of molecules, paleontologists who try to reconstruct how dinosaurs walked, and climatologists who study how human activities affect the atmosphere and oceans. Physics is also the foundation of all engineering and technology. No engineer could design a flat-screen TV, an interplanetary spacecraft, or even a better mousetrap without first understanding the basic laws of physic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecules
A molecule is a group of two or more atoms held together by attractive forces known as chemical bonds; depending on context, the term may or may not include ions which satisfy this criterion. In quantum physics, organic chemistry, and biochemistry, the distinction from ions is dropped and ''molecule'' is often used when referring to polyatomic ions. A molecule may be homonuclear, that is, it consists of atoms of one chemical element, e.g. two atoms in the oxygen molecule (O2); or it may be heteronuclear, a chemical compound composed of more than one element, e.g. water (molecule), water (two hydrogen atoms and one oxygen atom; H2O). In the kinetic theory of gases, the term ''molecule'' is often used for any gaseous particle regardless of its composition. This relaxes the requirement that a molecule contains two or more atoms, since the noble gases are individual atoms. Atoms and complexes connected by non-covalent interactions, such as hydrogen bonds or ionic bonds, are typic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Optical Tweezers
Optical tweezers (originally called single-beam gradient force trap) are scientific instruments that use a highly focused laser beam to hold and move microscopic and sub-microscopic objects like atoms, nanoparticles and droplets, in a manner similar to tweezers. If the object is held in air or vacuum without additional support, it can be called optical levitation. The laser light provides an attractive or repulsive force (typically on the order of pico newtons), depending on the relative refractive index between particle and surrounding medium. Levitation is possible if the force of the light counters the force of gravity. The trapped particles are usually micron-sized, or even smaller. Dielectric and absorbing particles can be trapped, too. Optical tweezers are used in biology and medicine (for example to grab and hold a single bacterium, a cell like a sperm cell or a blood cell, or a molecule like DNA), nanoengineering and nanochemistry (to study and build materials from sing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Single-molecule Experiment
A single-molecule experiment is an experiment that investigates the properties of individual molecules. Single-molecule studies may be contrasted with measurements on an ensemble or bulk collection of molecules, where the individual behavior of molecules cannot be distinguished, and only average characteristics can be measured. Since many measurement techniques in biology, chemistry, and physics are not sensitive enough to observe single molecules, single-molecule fluorescence techniques (that have emerged since the 1990s for probing various processes on the level of individual molecules) caused a lot of excitement, since these supplied many new details on the measured processes that were not accessible in the past. Indeed, since the 1990s, many techniques for probing individual molecules have been developed. The first single-molecule experiments were patch clamp experiments performed in the 1970s, but these were limited to studying ion channels. Today, systems investigated using s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nucleoprotein
Nucleoproteins are proteins conjugated with nucleic acids (either DNA or RNA). Typical nucleoproteins include ribosomes, nucleosomes and viral nucleocapsid proteins. Structures Nucleoproteins tend to be positively charged, facilitating interaction with the negatively charged nucleic acid chains. The tertiary structures and biological functions of many nucleoproteins are understood.Graeme K. Hunter G. K. (2000): Vital Forces. The discovery of the molecular basis of life. Academic Press, London 2000, . Important techniques for determining the structures of nucleoproteins include X-ray diffraction, nuclear magnetic resonance and cryo-electron microscopy. Viruses Virus genomes (either DNA virus, DNA or RNA virus, RNA) are extremely tightly packed into the Capsid, viral capsid. Many viruses are therefore little more than an organised collection of nucleoproteins with their binding sites pointing inwards. Structurally characterised viral nucleoproteins include Influenza A virus, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Imaging
Chemical imaging (as quantitative – ''chemical mapping'') is the analytical capability to create a visual image of components distribution from simultaneous measurement of spectra and spatial, time information. Hyperspectral imaging measures contiguous spectral bands, as opposed to multispectral imaging which measures spaced spectral bands. The main idea - for chemical imaging, the analyst may choose to take as many data spectrum measured at a particular chemical component in spatial location at time; this is useful for chemical identification and quantification. Alternatively, selecting an image plane at a particular data spectrum ( PCA - multivariable data of wavelength, spatial location at time) can map the spatial distribution of sample components, provided that their spectral signatures are different at the selected data spectrum. Software for chemical imaging is most specific and distinguished from chemical methods such as chemometrics. Imaging instrumentation has three co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Single-molecule
A single-molecule experiment is an experiment that investigates the properties of individual molecules. Single-molecule studies may be contrasted with measurements on an ensemble or bulk collection of molecules, where the individual behavior of molecules cannot be distinguished, and only average characteristics can be measured. Since many measurement techniques in biology, chemistry, and physics are not sensitive enough to observe single molecules, single-molecule fluorescence techniques (that have emerged since the 1990s for probing various processes on the level of individual molecules) caused a lot of excitement, since these supplied many new details on the measured processes that were not accessible in the past. Indeed, since the 1990s, many techniques for probing individual molecules have been developed. The first single-molecule experiments were patch clamp experiments performed in the 1970s, but these were limited to studying ion channels. Today, systems investigated using ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Oregon
The University of Oregon (UO, U of O or Oregon) is a public research university in Eugene, Oregon. Founded in 1876, the institution is well known for its strong ties to the sports apparel and marketing firm Nike, Inc, and its co-founder, billionaire Phil Knight. UO is also known for serving as the filming location for the 1978 cult classic ''National Lampoon's Animal House''. UO's 295-acre campus is situated along the Willamette River. The school also has a satellite campus in Portland; a marine station, called the Oregon Institute of Marine Biology, in Charleston; and an observatory, called Pine Mountain Observatory, in Central Oregon. UO's colors are green and yellow. The University of Oregon is organized into nine colleges and schools: the College of Arts and Sciences, Charles H. Lundquist College of Business, College of Design, College of Education, Robert D. Clark Honors College, School of Journalism and Communication; School of Law; School of Music and Dance; and the Gra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
HHMI
The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, film director, and philanthropist, known during his lifetime as one of the most financially successful individuals in the world. It is one of the largest private funding organizations for biological and medical research in the United States. HHMI spends about $1 million per HHMI Investigator per year, which amounts to annual investment in biomedical research of about $825 million. The institute has an endowment of $22.6 billion, making it the second-wealthiest philanthropic organization in the United States and the second-best endowed medical research foundation in the world. HHMI is the former owner of the Hughes Aircraft Company – an American aerospace firm which was divested to various firms over time. History The institute was fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marcos Maestre
Marcos may refer to: People with the given name ''Marcos'' *Marcos (given name) Sports ;Surnamed * Dayton Marcos, Negro league baseball team from Dayton, Ohio (early twentieth-century) * Dimitris Markos, Greek footballer * Nélson Marcos, Portuguese footballer * Randa Markos, Iraqi-Canadian female mixed martial artist ;Nicknamed * Marcos Joaquim dos Santos (born 1975), Brazilian footballer known as ''Marcos'' * Marcos de Paula (born 1983), Brazilian footballer known as ''Marcos'' playing for ''A.C. ChievoVerona'' * Marcos Alonso Peña (born 1959), Spanish footballer known as ''Marcos'' ;Named * Marcos Ambrose, Australian racing driver currently competing in ''NASCAR'' * Marcos Baghdatis, Cypriot tennis player * Marcos Hernández (swimmer), Cuban freestyle swimmer * Marcos Pizzelli, Brazilian-Armenian footballer * Marcos (footballer, born 1973), Brazilian football goalkeeper * Marcos García Barreno, Spanish footballer * Marcos Mazzaron, Brazilian cyclist * Marcos Carneiro de Mendo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biophysics
Biophysics is an interdisciplinary science that applies approaches and methods traditionally used in physics to study biological phenomena. Biophysics covers all scales of biological organization, from molecular to organismic and populations. Biophysical research shares significant overlap with biochemistry, molecular biology, physical chemistry, physiology, nanotechnology, bioengineering, computational biology, biomechanics, developmental biology and systems biology. The term ''biophysics'' was originally introduced by Karl Pearson in 1892.Roland Glaser. Biophysics: An Introduction'. Springer; 23 April 2012. . The term ''biophysics'' is also regularly used in academia to indicate the study of the physical quantities (e.g. electric current, temperature, stress, entropy) in biological systems. Other biological sciences also perform research on the biophysical properties of living organisms including molecular biology, cell biology, chemical biology, and biochemistry. Overview ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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