Carlos Bustamante (biophysicist)
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Carlos José Bustamante (born 1951 in
Lima Lima ( ; ), originally founded as Ciudad de Los Reyes (City of The Kings) is the capital and the largest city of Peru. It is located in the valleys of the Chillón River, Chillón, Rímac River, Rímac and Lurín Rivers, in the desert zone of t ...
,
Peru , image_flag = Flag of Peru.svg , image_coat = Escudo nacional del Perú.svg , other_symbol = Great Seal of the State , other_symbol_type = Seal (emblem), National seal , national_motto = "Fi ...
) is a Peruvian-American
scientist A scientist is a person who conducts Scientific method, scientific research to advance knowledge in an Branches of science, area of the natural sciences. In classical antiquity, there was no real ancient analog of a modern scientist. Instead, ...
. He is a member of the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...
.


Biography

Carlos Bustamante is a
Howard Hughes Medical Institute The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, fil ...
(HHMI) investigator,
professor Professor (commonly abbreviated as Prof.) is an Academy, academic rank at university, universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a "person who pr ...
of
molecular A molecule is a group of two or more atoms held together by attractive forces known as chemical bonds; depending on context, the term may or may not include ions which satisfy this criterion. In quantum physics, organic chemistry, and bioche ...
and cell biology,
physics Physics is the natural science that studies matter, its fundamental constituents, its motion and behavior through space and time, and the related entities of energy and force. "Physical science is that department of knowledge which r ...
, and
chemistry Chemistry is the science, scientific study of the properties and behavior of matter. It is a natural science that covers the Chemical element, elements that make up matter to the chemical compound, compounds made of atoms, molecules and ions ...
at the
University of California, Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California) is a public land-grant research university in Berkeley, California. Established in 1868 as the University of California, it is the state's first land-grant u ...
, and Biophysicist Faculty Scientist at the
Lawrence Berkeley National Laboratory Lawrence Berkeley National Laboratory (LBNL), commonly referred to as the Berkeley Lab, is a United States Department of Energy National Labs, United States national laboratory that is owned by, and conducts scientific research on behalf of, t ...
.
Bustamante studied medicine at
National University of San Marcos The National University of San Marcos ( es, Universidad Nacional Mayor de San Marcos, link=no, UNMSM) is a public research university located in Lima, the capital of Peru. It is considered the most important, recognized and representative educ ...
before discovering his true interest in biochemistry. He received his BSc from
Cayetano Heredia University Cayetano Heredia University ( es, link=no, Universidad Peruana Cayetano Heredia, UPCH; or simply ''Cayetano Heredia'') is a private nonprofit university located in Lima, Peru. It was named in honor of Cayetano Heredia, one of the eminent Peruv ...
in Lima, his MSc in
biochemistry Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and ...
from
National University of San Marcos The National University of San Marcos ( es, Universidad Nacional Mayor de San Marcos, link=no, UNMSM) is a public research university located in Lima, the capital of Peru. It is considered the most important, recognized and representative educ ...
in Lima, and his PhD in
biophysics Biophysics is an interdisciplinary science that applies approaches and methods traditionally used in physics to study biological phenomena. Biophysics covers all scales of biological organization, from molecular to organismic and populations. ...
from
UC Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California) is a public university, public land-grant university, land-grant research university in Berkeley, California. Established in 1868 as the University of Californi ...
, where he studied with Ignacio Tinoco, Jr. As a postdoctoral fellow at the
Lawrence Berkeley National Laboratory Lawrence Berkeley National Laboratory (LBNL), commonly referred to as the Berkeley Lab, is a United States Department of Energy National Labs, United States national laboratory that is owned by, and conducts scientific research on behalf of, t ...
, Bustamante studied with
Marcos Maestre Marcos may refer to: People with the given name ''Marcos'' *Marcos (given name) Sports ;Surnamed * Dayton Marcos, Negro league baseball team from Dayton, Ohio (early twentieth-century) * Dimitris Markos, Greek footballer * Nélson Marcos, Portugue ...
. Before moving to Berkeley, he was an
HHMI The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, fil ...
investigator at the
University of Oregon The University of Oregon (UO, U of O or Oregon) is a public research university in Eugene, Oregon. Founded in 1876, the institution is well known for its strong ties to the sports apparel and marketing firm Nike, Inc, and its co-founder, billion ...
.


Research focus

Carlos Bustamante uses novel methods of
single-molecule A single-molecule experiment is an experiment that investigates the properties of individual molecules. Single-molecule studies may be contrasted with measurements on an ensemble or bulk collection of molecules, where the individual behavior of mo ...
visualization Visualization or visualisation may refer to: *Visualization (graphics), the physical or imagining creation of images, diagrams, or animations to communicate a message * Data visualization, the graphic representation of data * Information visualiz ...
, such as scanning force microscopy, to study the structure and function of
nucleoprotein Nucleoproteins are proteins conjugated with nucleic acids (either DNA or RNA). Typical nucleoproteins include ribosomes, nucleosomes and viral nucleocapsid proteins. Structures Nucleoproteins tend to be positively charged, facilitating inte ...
assemblies. His laboratory is developing methods of single-molecule manipulation, such as
optical tweezers Optical tweezers (originally called single-beam gradient force trap) are scientific instruments that use a highly focused laser beam to hold and move microscopic and sub-microscopic objects like atoms, nanoparticles and droplets, in a manner simila ...
, to characterize the elasticity of DNA, to induce the mechanical unfolding of individual
protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
molecules A molecule is a group of two or more atoms held together by attractive forces known as chemical bonds; depending on context, the term may or may not include ions which satisfy this criterion. In quantum physics, organic chemistry, and bioche ...
, and to investigate the machine-like behavior of molecular motors.


Positions

* Research Assistant,
UC Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California) is a public university, public land-grant university, land-grant research university in Berkeley, California. Established in 1868 as the University of Californi ...
(1976–1981) * Postdoctoral Fellow, Lawrence Berkeley Laboratory,
UC Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California) is a public university, public land-grant university, land-grant research university in Berkeley, California. Established in 1868 as the University of Californi ...
(1981–1982) * Assistant Professor, Department of Chemistry,
University of New Mexico The University of New Mexico (UNM; es, Universidad de Nuevo México) is a public research university in Albuquerque, New Mexico. Founded in 1889, it is the state's flagship academic institution and the largest by enrollment, with over 25,400 ...
(1982–1986) * Associate Professor, Department of Chemistry,
University of New Mexico The University of New Mexico (UNM; es, Universidad de Nuevo México) is a public research university in Albuquerque, New Mexico. Founded in 1889, it is the state's flagship academic institution and the largest by enrollment, with over 25,400 ...
(1986–1989) * Professor of Chemistry, Department of Chemistry,
University of New Mexico The University of New Mexico (UNM; es, Universidad de Nuevo México) is a public research university in Albuquerque, New Mexico. Founded in 1889, it is the state's flagship academic institution and the largest by enrollment, with over 25,400 ...
(1989–1990) * Professor of Chemistry and Member of the Institute of Molecular Biology,
University of Oregon The University of Oregon (UO, U of O or Oregon) is a public research university in Eugene, Oregon. Founded in 1876, the institution is well known for its strong ties to the sports apparel and marketing firm Nike, Inc, and its co-founder, billion ...
(1991–1998) * Professor in Molecular and Cell Biology, Chemistry, and Physics,
UC Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California) is a public university, public land-grant university, land-grant research university in Berkeley, California. Established in 1868 as the University of Californi ...
(1998–present) * Honorary Professor,
National University of San Marcos The National University of San Marcos ( es, Universidad Nacional Mayor de San Marcos, link=no, UNMSM) is a public research university located in Lima, the capital of Peru. It is considered the most important, recognized and representative educ ...
, Lima, Peru


Fellowships and awards

* Kellogg Foundation scholarship during the Master in Biochemistry (1973–1975) *
Fulbright Commission The Fulbright Program, including the Fulbright–Hays Program, is one of several United States Cultural Exchange Programs with the goal of improving intercultural relations, cultural diplomacy, and intercultural competence between the people of ...
and
Institute of International Education The Institute of International Education (IIE) is a 501(c) organization which focuses on international student exchange and aid, foreign affairs, and international peace and security. IIE creates programs of study and training for students, educa ...
Fellow (1975–1976) *
Abraham Rosenberg Abraham, ; ar, , , name=, group= (originally Abram) is the common Hebrew patriarch of the Abrahamic religions, including Judaism, Christianity, and Islam. In Judaism, he is the founding father of the special relationship between the Jew ...
scholarship, UC Berkeley (1975–1976) *
Searle Scholar The Searle Scholars Program is a career development award made annually to the 15 young US professionals in biomedical research and chemistry considered most promising. The award was established in 1980 by a donation from the Searle family, and is ...
(1984) * Alfred P. Sloan Foundation Fellow (1985) * Presidential Lecturer in Chemistry, University of New Mexico (1986) * State of New Mexico Eminent Scholar (1989) *
Howard Hughes Medical Institute The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, fil ...
Investigator (1994–1998, 2000–present) * Elected Fellow of the
American Physical Society The American Physical Society (APS) is a not-for-profit membership organization of professionals in physics and related disciplines, comprising nearly fifty divisions, sections, and other units. Its mission is the advancement and diffusion of k ...
(1995), Citation: ''For pioneering the application of optical methods and scanning probes in measurements of the properties of single DNA molecules.'' * Member of the Science Advisory Board of the Searle Scholars Program (1997–2000) * Member of the Board of Trustees at the
IMDEA IMDEA () is a project founded by the Madrid Regional Government, included in the ''IV Regional Plan of Scientific Research and Technological Innovation 2005-2008 (PRICIT)'', for the purpose of setting up advanced research centers and higher educat ...
Nanoscience Institute * Elected member, National Academy of Sciences,
Biophysics Biophysics is an interdisciplinary science that applies approaches and methods traditionally used in physics to study biological phenomena. Biophysics covers all scales of biological organization, from molecular to organismic and populations. ...
2002 *
Max Delbrück Max Ludwig Henning Delbrück (; September 4, 1906 – March 9, 1981) was a German–American biophysicist who participated in launching the molecular biology research program in the late 1930s. He stimulated physical science, physical scientist ...
Prize in Biological Physics (2002) * Hans Neurath Award of the Protein Society (2004) * In 2005 he received the
Richtmyer Memorial Award The Richtmyer Memorial Award is an award for physics education, named for physicist Floyd K. Richtmyer and given annually by the American Association of Physics Teachers. Its recipients include over 15 Nobel Prize winners. Establishment and award c ...
given annually by the
American Association of Physics Teachers The American Association of Physics Teachers (AAPT) was founded in 1930 for the purpose of "dissemination of knowledge of physics, particularly by way of teaching." There are more than 10,000 members in over 30 countries. AAPT publications includ ...
. *
Alexander Hollaender Award in Biophysics The Alexander Hollaender Award in Biophysics is awarded by the U.S. National Academy of Sciences "for outstanding contributions in biophysics". Named in honor of Alexander Hollaender, it has been awarded every three years since 1998. Recipien ...
(2004) * Doctor Honoris Causa of
National University of San Marcos The National University of San Marcos ( es, Universidad Nacional Mayor de San Marcos, link=no, UNMSM) is a public research university located in Lima, the capital of Peru. It is considered the most important, recognized and representative educ ...
, Lima, Peru *
Vilcek Prize in Biomedical Science The Vilcek Foundation raises awareness of immigrant contributions to the United States, and fosters appreciation of the arts and sciences. The foundation's flagship programs include the Vilcek Foundation Prizes, which recognize and support immigr ...
(2012) * Raymond and Beverly Sackler International Prize in the Physical Sciences (2012)


References


External links

* {{DEFAULTSORT:Bustamante, Carlos 1951 births Members of the United States National Academy of Sciences Living people People from Lima Peruvian chemists American chemists Peruvian emigrants to the United States National University of San Marcos alumni University of California, Berkeley alumni Howard Hughes Medical Investigators University of Oregon faculty Fellows of the American Physical Society UC Berkeley College of Chemistry faculty Hispanic and Latino American scientists Hispanic and Latino American physicists