Clear-cell Tumor

	Clear-cell Tumor Clear-cell tumor (any with clear cells) can refer to: * clear-cell sarcoma, including ** clear-cell sarcoma of the kidney * clear-cell carcinoma, mostly ** clear-cell adenocarcinoma Clear-cell adenocarcinoma is a type of adenocarcinoma that shows clear cells. Types include: * Clear-cell adenocarcinoma of the vagina * Clear-cell ovarian carcinoma * Uterine clear-cell carcinoma Uterine clear-cell carcinoma (CC) is a rare ... {{disambig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
picture info	Clear Cell In histology, a clear cell is a cell that shows a clear cytoplasm when stained with hematoxylin and eosin (H&E). Normal histology In the skin, some secretory cells in the epithelium appear as clear cells, and are one of the components of eccrine sweat glands. A clear cell's plasma membrane is highly folded, more so on the apical and lateral surfaces. The cytoplasm of clear cells contains large amounts of glycogen and many mitochondria. Melanocytes appear as clear cells when in the stratum basale of the skin, and Langerhans' cells appear as clear cells in the stratum spinosum. C cells, more commonly referred to as parafollicular cells are type of cell found in the thyroid gland which stain clear using H&E. Clear cell cancers Clear-cell adenocarcinoma Clear-cell adenocarcinoma is a type of adenocarcinoma that shows clear cells. Types include: * Clear-cell adenocarcinoma of the vagina * Clear-cell ovarian carcinoma * Uterine clear-cell carcinoma Uterine clear-cell c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Clear-cell Sarcoma Clear cell sarcoma is a rare form of cancer called a sarcoma. It is known to occur mainly in the soft tissues and dermis. Rare forms were thought to occur in the gastrointestinal tract before they were discovered to be different and redesignated as GNET. Recurrence is common. Clear cell sarcoma's neoplastic cells express the ''EWSR1-ATF1'' fusion gene in a majority of cases or a ''EWSR1-CREB1'', ''EWSR1-CREM'', or ''EWSR1-DDIT3'' fusion gene in a small subset of cases (see FET gene family of fusion genes). Clear cell sarcoma of the soft tissues in adults is not related to the pediatric tumor known as clear cell sarcoma of the kidney. Signs and symptoms It presents as a slow growing mass that especially affects tendons and aponeuroses and it is deeply situated. Patients often perceive it as a lump or hard mass. It causes either pain or tenderness but only until it becomes large enough. This kind of tumor is commonly found in the extremities especially around the knee, feet and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Clear-cell Sarcoma Of The Kidney Clear cell sarcoma of the kidney (CCSK) is an extremely rare type of kidney cancer comprising 3% of all pediatric renal tumours. Clear cell sarcoma of the kidney can spread from the kidney to other organs, most commonly the bone, but also including the lungs, brain, and soft tissues of the body. Despite the similarities in names, clear cell sarcoma of the kidney is unrelated to clear cell sarcoma of soft tissue, also known as malignant melanoma of soft parts. Signs and symptoms Typical gross features include large size (mean diameter 11.3 cm), a mucoid texture, foci of necrosis, and prominent cyst formation. Cause Research in 2005 showed that CCSK can arise within a renal mesenchymal cell that shows a wide variety of neural markers. Typical presentation is between 1 and 4 years of age, and a 2:1 male-to-female ratio is observed. Treatment 2004 research showed that CCSK patients exhibit an improved relapse-free survival from a longer course of therapy when using vincristine, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]
	Clear-cell Carcinoma Clear-cell carcinoma, also known as clear-cell adenocarcinoma and mesonephroma, is an epithelial-cell-derived carcinoma characterized by the presence of clear cells observed during histological, diagnostic assessment. This form of cancer is classified as a rare cancer with an incidence of 4.8% in white patients, 3.1% in black patients, and 11.1% in Asian patients. Clear-cell carcinoma may arise in multiple tissue types including the kidney ( clear-cell renal-cell carcinoma), ovary (ovarian clear-cell carcinoma), uterus (uterine clear-cell carcinoma) or gastrointestinal tract (colorectal clear-cell carcinoma). Treatment options for clear cell carcinoma vary by the tissue type affected. It may include a combination of chemotherapy (paclitaxel and carboplatin or irinotecan plus cisplatin) and surgical resection in ovarian clear-cell carcinoma; debulking or resection paired with chemotherapy ( cisplatin) in ovarian clear-cell carcinoma; cytokine therapy (IL-2, interferon), kinase ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu]